Page last updated: 2024-10-24

candesartan and Glomerulonephritis

candesartan has been researched along with Glomerulonephritis in 7 studies

candesartan: a nonpeptide angiotensin II receptor antagonist
candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.

Glomerulonephritis: Inflammation of the renal glomeruli (KIDNEY GLOMERULUS) that can be classified by the type of glomerular injuries including antibody deposition, complement activation, cellular proliferation, and glomerulosclerosis. These structural and functional abnormalities usually lead to HEMATURIA; PROTEINURIA; HYPERTENSION; and RENAL INSUFFICIENCY.

Research Excerpts

ExcerptRelevanceReference
"Japanese patients with renal insufficiency were randomly assigned to receive either an ACE inhibitor (benazepril 1."5.12A five-year comparison of the renal protective effects of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in patients with non-diabetic nephropathy. ( Kanno, Y; Shoda, J; Suzuki, H, 2006)
"Candesartan promotes a complementary antiproteinuric and a small antihypertensive effect after a treatment period of 8 weeks in patients with chronic glomerulonephritis when given in conjunction with an ACEI."5.10Reduction of proteinuria; combined effects of receptor blockade and low dose angiotensin-converting enzyme inhibition. ( Bader, BD; Berger, ED; Ebert, C; Erley, CM; Risler, T, 2002)
"The antifibrotic substance pirfenidone and the angiotensin II type I receptor antagonist candesartan cilexetil, given alone and in combination, were tested in rats with chronic anti-glomerular basement membrane glomerulonephritis (anti-GBM GN)."3.73Pirfenidone and candesartan ameliorate morphological damage in mild chronic anti-GBM nephritis in rats. ( Forslund, T; Iversen, BM; Leh, S; Margolin, SB; Vaagnes, Ø, 2005)
"5-year prospective study compared the effects of angiotensin II receptor blocker, candesartan(n = 21), and ACE inhibitor(ACEI, n = 23) on proteinuria and renal function in patients with moderate renal impairment due to chronic glomerulonephritis."3.71[Comparison of ARB and ACEI for renoprotection in chronic glomerulonephritis]. ( Iigaya, K; Imai, M; Kumagai, H; Matsuura, T; Onami, T; Sakata, K; Saruta, T, 2002)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's6 (85.71)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kumagai, H1
Sakata, K1
Matsuura, T1
Imai, M1
Onami, T1
Iigaya, K1
Saruta, T1
Hollenberg, NK1
Leh, S1
Vaagnes, Ø1
Margolin, SB1
Iversen, BM1
Forslund, T1
Chang, A1
Logar, CM1
Finn, LS1
Alpers, CE1
Seliger, SL1
Shoda, J1
Kanno, Y1
Suzuki, H1
Kurokawa, K1
Berger, ED1
Bader, BD1
Ebert, C1
Risler, T1
Erley, CM1

Trials

3 trials available for candesartan and Glomerulonephritis

ArticleYear
Reduction of proteinuria; combined effects of receptor blockade and low dose angiotensin-converting enzyme inhibition.
    Current hypertension reports, 2003, Volume: 5, Issue:4

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents;

2003
A five-year comparison of the renal protective effects of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in patients with non-diabetic nephropathy.
    Internal medicine (Tokyo, Japan), 2006, Volume: 45, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Ben

2006
Reduction of proteinuria; combined effects of receptor blockade and low dose angiotensin-converting enzyme inhibition.
    Journal of hypertension, 2002, Volume: 20, Issue:4

    Topics: Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihyperte

2002

Other Studies

4 other studies available for candesartan and Glomerulonephritis

ArticleYear
[Comparison of ARB and ACEI for renoprotection in chronic glomerulonephritis].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60, Issue:10

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl

2002
Pirfenidone and candesartan ameliorate morphological damage in mild chronic anti-GBM nephritis in rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2005, Volume: 20, Issue:1

    Topics: Analysis of Variance; Animals; Antibodies; Autoantibodies; Base Sequence; Benzimidazoles; Biopsy, Ne

2005
A rare cause of necrotizing and crescentic glomerulonephritis in a young adult male.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 45, Issue:5

    Topics: Adolescent; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Autoa

2005
Effects of candesartan on the proteinuria of chronic glomerulonephritis.
    Journal of human hypertension, 1999, Volume: 13 Suppl 1

    Topics: Adult; Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Arterioles; Benzimidazoles;

1999