Page last updated: 2024-10-24

candesartan and Cerebral Hemorrhage

candesartan has been researched along with Cerebral Hemorrhage in 5 studies

candesartan: a nonpeptide angiotensin II receptor antagonist
candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.

Cerebral Hemorrhage: Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.

Research Excerpts

ExcerptRelevanceReference
" We assessed the effects of treatment with candesartan in acute ICH and according to different types of hematoma."9.30Effects of Candesartan in the Acute Phase of Intracerebral Hemorrhage. ( Anderson, C; Bath, PM; Berge, E; Berge, TE; Delcourt, C; Guo, R; Jusufovic, M; Karlson, BW; Sandset, EC; You, S, 2019)
"Scandinavian Candesartan Acute Stroke Trial was a randomized controlled and placebo-controlled trial of candesartan within 30 h of ischaemic or haemorrhagic stroke."9.22Early blood pressure lowering treatment in acute stroke. Ordinal analysis of vascular events in the Scandinavian Candesartan Acute Stroke Trial (SCAST). ( Bath, PM; Berge, E; Jusufovic, M; Sandset, EC, 2016)
"There was no indication that careful blood-pressure lowering treatment with the angiotensin-receptor blocker candesartan is beneficial in patients with acute stroke and raised blood pressure."9.15The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind trial. ( Bath, PM; Berge, E; Boysen, G; Jatuzis, D; Kõrv, J; Lüders, S; Murray, GD; Richter, PS; Roine, RO; Sandset, EC; Terént, A; Thijs, V, 2011)
" We assessed the effects of treatment with candesartan in acute ICH and according to different types of hematoma."5.30Effects of Candesartan in the Acute Phase of Intracerebral Hemorrhage. ( Anderson, C; Bath, PM; Berge, E; Berge, TE; Delcourt, C; Guo, R; Jusufovic, M; Karlson, BW; Sandset, EC; You, S, 2019)
"Scandinavian Candesartan Acute Stroke Trial was a randomized controlled and placebo-controlled trial of candesartan within 30 h of ischaemic or haemorrhagic stroke."5.22Early blood pressure lowering treatment in acute stroke. Ordinal analysis of vascular events in the Scandinavian Candesartan Acute Stroke Trial (SCAST). ( Bath, PM; Berge, E; Jusufovic, M; Sandset, EC, 2016)
"The Scandinavian Candesartan Acute Stroke Trial (SCAST) found no benefits of candesartan in acute stroke."5.16Relation between change in blood pressure in acute stroke and risk of early adverse events and poor outcome. ( Bath, PM; Berge, E; Kjeldsen, SE; Murray, GD; Sandset, EC, 2012)
"There was no indication that careful blood-pressure lowering treatment with the angiotensin-receptor blocker candesartan is beneficial in patients with acute stroke and raised blood pressure."5.15The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind trial. ( Bath, PM; Berge, E; Boysen, G; Jatuzis, D; Kõrv, J; Lüders, S; Murray, GD; Richter, PS; Roine, RO; Sandset, EC; Terént, A; Thijs, V, 2011)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jusufovic, M2
Berge, TE1
Guo, R1
You, S1
Delcourt, C1
Anderson, C1
Bath, PM4
Karlson, BW1
Berge, E4
Sandset, EC4
Boysen, G1
Jatuzis, D1
Kõrv, J1
Lüders, S1
Murray, GD2
Richter, PS1
Roine, RO1
Terént, A1
Thijs, V1
Kjeldsen, SE1
Fukui, T1
Rahman, M1
Hayashi, K1
Takeda, K1
Higaki, J1
Sato, T1
Fukushima, M1
Sakamoto, J1
Morita, S1
Ogihara, T1
Fukiyama, K1
Fujishima, M1
Saruta, T1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Scandinavian Candesartan Acute Stroke Trial[NCT00120003]Phase 32,500 participants (Anticipated)Interventional2005-06-30Completed
A Multi-center Randomised Controlled Trial to Explore the Ideal Individualized Anti-hypertension Strategies in Patients With Severe Stroke at Acute Stage[NCT02982655]500 participants (Anticipated)Interventional2017-01-31Completed
Comparison of Peripheral and Cerebral Arterial Flow in Acute Ischemic Stroke: Fimasartan vs. Valsartan vs. Atenolol[NCT02403349]Phase 4105 participants (Actual)Interventional2012-05-31Active, not recruiting
Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) Trial of Cardiovascular Events in High-Risk Hypertensive Patients[NCT00125463]Phase 33,200 participants Interventional2001-09-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for candesartan and Cerebral Hemorrhage

ArticleYear
Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial of cardiovascular events in high-risk hypertensive patients: rationale, design, and methods.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2003, Volume: 26, Issue:12

    Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cerebral Hemorrhage; Cerebral Infarctio

2003

Trials

4 trials available for candesartan and Cerebral Hemorrhage

ArticleYear
Effects of Candesartan in the Acute Phase of Intracerebral Hemorrhage.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2019, Volume: 28, Issue:8

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimida

2019
Early blood pressure lowering treatment in acute stroke. Ordinal analysis of vascular events in the Scandinavian Candesartan Acute Stroke Trial (SCAST).
    Journal of hypertension, 2016, Volume: 34, Issue:8

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure

2016
The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind trial.
    Lancet (London, England), 2011, Feb-26, Volume: 377, Issue:9767

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimida

2011
The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind trial.
    Lancet (London, England), 2011, Feb-26, Volume: 377, Issue:9767

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimida

2011
The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind trial.
    Lancet (London, England), 2011, Feb-26, Volume: 377, Issue:9767

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimida

2011
The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind trial.
    Lancet (London, England), 2011, Feb-26, Volume: 377, Issue:9767

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimida

2011
The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind trial.
    Lancet (London, England), 2011, Feb-26, Volume: 377, Issue:9767

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimida

2011
The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind trial.
    Lancet (London, England), 2011, Feb-26, Volume: 377, Issue:9767

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimida

2011
The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind trial.
    Lancet (London, England), 2011, Feb-26, Volume: 377, Issue:9767

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimida

2011
The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind trial.
    Lancet (London, England), 2011, Feb-26, Volume: 377, Issue:9767

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimida

2011
The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind trial.
    Lancet (London, England), 2011, Feb-26, Volume: 377, Issue:9767

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimida

2011
Relation between change in blood pressure in acute stroke and risk of early adverse events and poor outcome.
    Stroke, 2012, Volume: 43, Issue:8

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Com

2012