candesartan has been researched along with Brain Swelling in 8 studies
candesartan: a nonpeptide angiotensin II receptor antagonist
candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neurovascular protection against cerebral ischemia is not consistently observed with a postischemia hypotensive dose of candesartan." | 7.77 | Therapeutic effects of postischemic treatment with hypotensive doses of an angiotensin II receptor blocker on transient focal cerebral ischemia. ( Fu, H; Hosomi, N; Itano, T; Kohno, M; Liu, G; Masugata, H; Matsumoto, M; Miki, T; Nakano, D; Nishiyama, A; Pelisch, N; Sueda, Y; Ueno, M, 2011) |
| "To determine whether BP lowering with candesartan, initiated at reperfusion, can reduce neurovascular damage and improve outcome in a model of hypertension after experimental ischemic stroke." | 7.73 | Hypertension after experimental cerebral ischemia: candesartan provides neurovascular protection. ( Ergul, A; Fagan, SC; Hess, DC; Hill, WD; Johnson, MH; Kozak, A; Pollock, DM; Xu, L, 2006) |
| "Candesartan treatment normalized blood pressure and the shift toward higher blood pressures at both the upper and lower limits of cerebrovascular autoregulation in SHR." | 5.31 | Angiotensin II AT(1) blockade normalizes cerebrovascular autoregulation and reduces cerebral ischemia in spontaneously hypertensive rats. ( Ito, T; Nishimura, Y; Saavedra, JM, 2000) |
| "Neurovascular protection against cerebral ischemia is not consistently observed with a postischemia hypotensive dose of candesartan." | 3.77 | Therapeutic effects of postischemic treatment with hypotensive doses of an angiotensin II receptor blocker on transient focal cerebral ischemia. ( Fu, H; Hosomi, N; Itano, T; Kohno, M; Liu, G; Masugata, H; Matsumoto, M; Miki, T; Nakano, D; Nishiyama, A; Pelisch, N; Sueda, Y; Ueno, M, 2011) |
| "To determine whether BP lowering with candesartan, initiated at reperfusion, can reduce neurovascular damage and improve outcome in a model of hypertension after experimental ischemic stroke." | 3.73 | Hypertension after experimental cerebral ischemia: candesartan provides neurovascular protection. ( Ergul, A; Fagan, SC; Hess, DC; Hill, WD; Johnson, MH; Kozak, A; Pollock, DM; Xu, L, 2006) |
| "Candesartan (0·05 mg/kg) was administered just after initiation of ischaemia followed by a repeat administration at 24 h while 1, 5 isoquinolinediol (0·1 mg/kg) was given one-hour after of ischaemia." | 1.40 | A comparative study of neuroprotective effect of single and combined blockade of AT1 receptor and PARP-1 in focal cerebral ischaemia in rat. ( Hanif, K; Sharma, G; Singh, N, 2014) |
| "Focal cerebral ischemia, induced by middle cerebral artery occlusion/reperfusion (MCAO), was conducted at 4 wk after STZ injection." | 1.32 | Role of AT1 receptors and NAD(P)H oxidase in diabetes-aggravated ischemic brain injury. ( Granger, DN; Ishikawa, M; Kusaka, G; Kusaka, I; Nanda, A; Tang, J; Zhang, JH; Zhou, C, 2004) |
| "Candesartan treatment normalized blood pressure and the shift toward higher blood pressures at both the upper and lower limits of cerebrovascular autoregulation in SHR." | 1.31 | Angiotensin II AT(1) blockade normalizes cerebrovascular autoregulation and reduces cerebral ischemia in spontaneously hypertensive rats. ( Ito, T; Nishimura, Y; Saavedra, JM, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Panahpour, H | 1 |
| Nekooeian, AA | 1 |
| Dehghani, GA | 1 |
| Fu, H | 1 |
| Hosomi, N | 1 |
| Pelisch, N | 1 |
| Nakano, D | 1 |
| Liu, G | 1 |
| Ueno, M | 1 |
| Miki, T | 1 |
| Masugata, H | 1 |
| Sueda, Y | 1 |
| Itano, T | 1 |
| Matsumoto, M | 1 |
| Nishiyama, A | 1 |
| Kohno, M | 1 |
| Singh, N | 2 |
| Sharma, G | 1 |
| Hanif, K | 1 |
| Yamakawa, H | 1 |
| Jezova, M | 1 |
| Ando, H | 1 |
| Saavedra, JM | 2 |
| Kusaka, I | 1 |
| Kusaka, G | 1 |
| Zhou, C | 1 |
| Ishikawa, M | 1 |
| Nanda, A | 1 |
| Granger, DN | 1 |
| Zhang, JH | 1 |
| Tang, J | 1 |
| Fagan, SC | 1 |
| Kozak, A | 1 |
| Hill, WD | 1 |
| Pollock, DM | 1 |
| Xu, L | 1 |
| Johnson, MH | 1 |
| Ergul, A | 1 |
| Hess, DC | 1 |
| Brdon, J | 1 |
| Kaiser, S | 1 |
| Hagemann, F | 1 |
| Zhao, Y | 1 |
| Culman, J | 1 |
| Gohlke, P | 1 |
| Nishimura, Y | 1 |
| Ito, T | 1 |
8 other studies available for candesartan and Brain Swelling
| Article | Year |
|---|---|
Candesartan attenuates ischemic brain edema and protects the blood-brain barrier integrity from ischemia/reperfusion injury in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood-Brain Ba | 2014 |
Therapeutic effects of postischemic treatment with hypotensive doses of an angiotensin II receptor blocker on transient focal cerebral ischemia.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Benzimidazoles; B | 2011 |
A comparative study of neuroprotective effect of single and combined blockade of AT1 receptor and PARP-1 in focal cerebral ischaemia in rat.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Brain; Brain E | 2014 |
Normalization of endothelial and inducible nitric oxide synthase expression in brain microvessels of spontaneously hypertensive rats by angiotensin II AT1 receptor inhibition.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Arterial Occlusive Diseases; Ben | 2003 |
Role of AT1 receptors and NAD(P)H oxidase in diabetes-aggravated ischemic brain injury.
Topics: Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Blood Pressure; | 2004 |
Hypertension after experimental cerebral ischemia: candesartan provides neurovascular protection.
Topics: Animals; Antihypertensive Agents; Behavior, Animal; Benzimidazoles; Biphenyl Compounds; Blood Pressu | 2006 |
Comparison between early and delayed systemic treatment with candesartan of rats after ischaemic stroke.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure | 2007 |
Angiotensin II AT(1) blockade normalizes cerebrovascular autoregulation and reduces cerebral ischemia in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; | 2000 |