Page last updated: 2024-10-24

candesartan and Aortic Stenosis

candesartan has been researched along with Aortic Stenosis in 6 studies

candesartan: a nonpeptide angiotensin II receptor antagonist
candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to evaluate whether treatment with candesartan on top of conventional treatment could prevent new onset AF in patients with aortic valve stenosis (AS) after aortic valve replacement."9.17Prevention of atrial fibrillation in patients with aortic valve stenosis with candesartan treatment after aortic valve replacement. ( Andersen, LI; Dahl, JS; Haghfelt, T; Møller, JE; Pellikka, PA; Poulsen, MK; Veien, K; Videbæk, L, 2013)
" The aim of this study was to evaluate whether treatment with candesartan on top of conventional treatment could prevent new onset AF in patients with aortic valve stenosis (AS) after aortic valve replacement."5.17Prevention of atrial fibrillation in patients with aortic valve stenosis with candesartan treatment after aortic valve replacement. ( Andersen, LI; Dahl, JS; Haghfelt, T; Møller, JE; Pellikka, PA; Poulsen, MK; Veien, K; Videbæk, L, 2013)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Helske-Suihko, S1
Laine, M1
Lommi, J1
Kaartinen, M1
Werkkala, K1
Kovanen, PT1
Kupari, M1
Dahl, JS3
Videbaek, L1
Poulsen, MK3
Pellikka, PA3
Veien, K2
Andersen, LI2
Haghfelt, T2
Møller, JE3
Benedetto, U1
Melina, G1
Refice, S1
di Bartolomeo, R1
Roscitano, A1
Angeloni, E1
Sinatra, R1
Pocock, SJ1
Ariti, CA1
Collier, TJ1
Wang, D1
Videbæk, L2
Rudbæk, TR1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Potential of Candesartan to Retard the Progression of Aortic Stenosis Influences of Medical Therapy to the Atheroinflammatory Process in Stenotic Aortic Valves[NCT00699452]Phase 3120 participants (Anticipated)Interventional2009-05-31Recruiting
Beneficio Del Bloqueo Del Sistema Renina-angiotensina Sobre la evolución clínica y el Remodelado Ventricular Tras la colocación de Una prótesis percutánea aórtica (RASTAVI)[NCT03201185]Phase 4194 participants (Actual)Interventional2018-02-10Active, not recruiting
Efficacy and Safety of Treatment With Convalescent Plasma for Adults With COVID-19 Pneumonia. A Double-blinded, Randomized, Multicenter Placebo-controlled Trial[NCT04345289]Phase 3147 participants (Actual)Interventional2020-05-01Terminated (stopped due to DSMB advise due to high probability of futility)
Left Ventricular Reverse Remodelling After Aortic Valve Replacement in Severe Valvular Aortic Stenosis - Effect of Blockade of the Angiotensin-II Receptor[NCT00294775]Phase 3140 participants (Anticipated)Interventional2006-02-28Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for candesartan and Aortic Stenosis

ArticleYear
Is blockade of the Renin-Angiotensin system able to reverse the structural and functional remodeling of the left ventricle in severe aortic stenosis?
    Journal of cardiovascular pharmacology, 2015, Volume: 65, Issue:3

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Aortic Valve Stenosis; Benzimidazo

2015
Effect of candesartan treatment on left ventricular remodeling after aortic valve replacement for aortic stenosis.
    The American journal of cardiology, 2010, Sep-01, Volume: 106, Issue:5

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Aortic Valve Stenosis; Benzimidazo

2010
Dual renin-angiotensin system blockade for patients with prosthesis-patient mismatch.
    The Annals of thoracic surgery, 2010, Volume: 90, Issue:6

    Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-C

2010
Prevention of atrial fibrillation in patients with aortic valve stenosis with candesartan treatment after aortic valve replacement.
    International journal of cardiology, 2013, May-10, Volume: 165, Issue:2

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Aortic Valve Stenosis; Atrial Fibr

2013
Global strain in severe aortic valve stenosis: relation to clinical outcome after aortic valve replacement.
    Circulation. Cardiovascular imaging, 2012, Sep-01, Volume: 5, Issue:5

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Aortic Valve; Aortic Valve Stenosi

2012

Other Studies

1 other study available for candesartan and Aortic Stenosis

ArticleYear
The win ratio: a new approach to the analysis of composite endpoints in clinical trials based on clinical priorities.
    European heart journal, 2012, Volume: 33, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Aortic Valve Stenosis; Benzimidazoles; Biphenyl Compounds;

2012