candesartan has been researched along with Aging in 10 studies
candesartan: a nonpeptide angiotensin II receptor antagonist
candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We hypothesized that aging results in enhanced early reperfusion injury and left ventricular remodeling after reperfused ST-segment-elevation myocardial infarction and that early therapy initiated at the time of reperfusion with an angiotensin II type 1 receptor blocker such as candesartan attenuates age-related increases in reperfusion injury and remodeling." | 3.76 | Aging-related early changes in markers of ventricular and matrix remodeling after reperfused ST-segment elevation myocardial infarction in the canine model: effect of early therapy with an angiotensin II type 1 receptor blocker. ( Idikio, H; Jelani, A; Jugdutt, BI; Jugdutt, CE; Menon, V; Palaniyappan, A; Uweira, RE, 2010) |
| "Candesartan treatment completely suppressed the increases of p21, p27, p53 and Rb." | 1.33 | Angiotensin II receptor antagonist attenuates expression of aging markers in diabetic mouse heart. ( Izumi, T; Kosugi, R; Machida, Y; Shioi, T; Takahashi, K; Watanabe-Maeda, K; Yoshida, Y, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elkahloun, AG | 1 |
| Saavedra, JM | 1 |
| Jugdutt, BI | 1 |
| Jelani, A | 1 |
| Palaniyappan, A | 1 |
| Idikio, H | 1 |
| Uweira, RE | 1 |
| Menon, V | 1 |
| Jugdutt, CE | 1 |
| Villar-Cheda, B | 1 |
| Valenzuela, R | 1 |
| Rodriguez-Perez, AI | 1 |
| Guerra, MJ | 1 |
| Labandeira-Garcia, JL | 1 |
| Chugh, G | 1 |
| Lokhandwala, MF | 1 |
| Asghar, M | 1 |
| Reverte, V | 1 |
| Tapia, A | 1 |
| Baile, G | 1 |
| Gambini, J | 1 |
| Gíménez, I | 1 |
| Llinas, MT | 1 |
| Salazar, FJ | 1 |
| Fujii, K | 1 |
| Abe, I | 1 |
| Sakima, A | 2 |
| Averill, DB | 1 |
| Gallagher, PE | 1 |
| Kasper, SO | 1 |
| Tommasi, EN | 1 |
| Ferrario, CM | 2 |
| Diz, DI | 2 |
| Stevanovic, RD | 1 |
| Price, DA | 1 |
| Lansang, MC | 1 |
| Fisher, ND | 1 |
| Laffel, LM | 1 |
| Hollenberg, NK | 1 |
| Kosugi, R | 1 |
| Shioi, T | 1 |
| Watanabe-Maeda, K | 1 |
| Yoshida, Y | 1 |
| Takahashi, K | 1 |
| Machida, Y | 1 |
| Izumi, T | 1 |
| Arnold, AC | 1 |
| Ganten, D | 1 |
1 review available for candesartan and Aging
| Article | Year |
|---|---|
[Angiotensin II receptor antagonist improves age-related impairment of EDHF-mediated hyperpolarization].
Topics: Aging; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biological Factors; Biphenyl Compo | 2002 |
1 trial available for candesartan and Aging
| Article | Year |
|---|---|
Renin release in response to Renin system blockade: activation of the Renin system in type 1 diabetes mellitus.
Topics: Adult; Aged; Aging; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Ca | 2005 |
8 other studies available for candesartan and Aging
| Article | Year |
|---|---|
Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis.
Topics: Aging; Animals; Benzimidazoles; Biphenyl Compounds; Cellular Senescence; Glutamic Acid; Hippocampus; | 2020 |
Aging-related early changes in markers of ventricular and matrix remodeling after reperfused ST-segment elevation myocardial infarction in the canine model: effect of early therapy with an angiotensin II type 1 receptor blocker.
Topics: Aging; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; A | 2010 |
Aging-related changes in the nigral angiotensin system enhances proinflammatory and pro-oxidative markers and 6-OHDA-induced dopaminergic degeneration.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Co | 2012 |
Oxidative stress alters renal D1 and AT1 receptor functions and increases blood pressure in old rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Antioxidants; Benzimidaz | 2011 |
Role of angiotensin II in arterial pressure and renal hemodynamics in rats with altered renal development: age- and sex-dependent differences.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arterial Pressure; Benzimid | 2013 |
Impaired heart rate baroreflex in older rats: role of endogenous angiotensin-(1-7) at the nucleus tractus solitarii.
Topics: Aging; Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Animals; Baroreflex; Benzimidazoles; | 2005 |
Angiotensin II receptor antagonist attenuates expression of aging markers in diabetic mouse heart.
Topics: Aging; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biomarkers; Biphenyl Compou | 2006 |
Modulation of reflex function by endogenous angiotensins in older transgenic rats with low glial angiotensinogen.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Angi | 2008 |