candesartan has been researched along with Acute Liver Injury, Drug-Induced in 9 studies
candesartan: a nonpeptide angiotensin II receptor antagonist
candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Candesartan was withdrawn, with a progressive improvement in cholestasis and complete normalization of liver biochemistry at 6 months." | 5.56 | Candesartan-induced cholestatic hepatitis: a case report. ( García López, R; Hermida Pérez, B; Izquierdo Romero, M, 2020) |
| "Arterial hypertension is a highly manageable disorder due to a variety of drugs available for its treatment." | 2.58 | Noncholestatic acute hepatocellular injury following candesartan administration. ( DeObeso-Gonzalez, E; Flores-Villalba, E; Lammel-Lindemann, JA; Martagón, AJ; Puente-Gallegos, F, 2018) |
| "Candesartan was withdrawn, with a progressive improvement in cholestasis and complete normalization of liver biochemistry at 6 months." | 1.56 | Candesartan-induced cholestatic hepatitis: a case report. ( García López, R; Hermida Pérez, B; Izquierdo Romero, M, 2020) |
| " An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems." | 1.36 | Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Greene, N | 1 |
| Fisk, L | 1 |
| Naven, RT | 1 |
| Note, RR | 1 |
| Patel, ML | 1 |
| Pelletier, DJ | 1 |
| Ekins, S | 1 |
| Williams, AJ | 1 |
| Xu, JJ | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Hermida Pérez, B | 1 |
| Izquierdo Romero, M | 1 |
| García López, R | 1 |
| Lammel-Lindemann, JA | 1 |
| Flores-Villalba, E | 1 |
| Martagón, AJ | 1 |
| DeObeso-Gonzalez, E | 1 |
| Puente-Gallegos, F | 1 |
| Jiménez-Sáenz, M | 1 |
| Arroyo, Q | 1 |
| Sanjuan, M | 1 |
| Herrerías, JM | 1 |
| Vallejo, I | 1 |
| García Morillo, S | 1 |
| Pamies, E | 1 |
| González-Jiménez, D | 1 |
| Varela, JM | 1 |
| Calderón, E | 1 |
| Galindo, J | 1 |
| González de la Puente, MA | 1 |
2 reviews available for candesartan and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
Noncholestatic acute hepatocellular injury following candesartan administration.
Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; | 2018 |
7 other studies available for candesartan and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Candesartan-induced cholestatic hepatitis: a case report.
Topics: Benzimidazoles; Biphenyl Compounds; Chemical and Drug Induced Liver Injury; Cholestasis; Hepatitis; | 2020 |
[Candesartan-induced cholestatic hepatitis: a case report].
Topics: Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Chem | 2010 |
[Acute hepatitis induced by candesartan].
Topics: Acute Disease; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Chemica | 2000 |
Candesartan and acute liver injury.
Topics: Acute Disease; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazol | 2000 |