candesartan has been researched along with Acute Brain Injuries in 5 studies
candesartan: a nonpeptide angiotensin II receptor antagonist
candesartan : A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Candesartan treatment reduced the lesion volume after CCI injury by approximately 50%, decreased the number of dying neurons, lessened the number of activated microglial cells, protected cerebral blood flow (CBF), and reduced the expression of the cytokine TGFβ1 while increasing expression of TGFβ3." | 1.38 | Candesartan, an angiotensin II AT₁-receptor blocker and PPAR-γ agonist, reduces lesion volume and improves motor and memory function after traumatic brain injury in mice. ( Logan, TT; Saavedra, JM; Sánchez-Lemus, E; Symes, AJ; Villapol, S; Yaszemski, AK, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Timaru-Kast, R | 1 |
| Coronel-Castello, SP | 1 |
| Krämer, TJ | 1 |
| Hugonnet, AV | 1 |
| Schäfer, MKE | 1 |
| Sebastiani, A | 1 |
| Thal, SC | 1 |
| Panahpour, H | 1 |
| Nekooeian, AA | 1 |
| Dehghani, GA | 1 |
| Villapol, S | 2 |
| Balarezo, MG | 1 |
| Affram, K | 1 |
| Saavedra, JM | 2 |
| Symes, AJ | 2 |
| Yaszemski, AK | 1 |
| Logan, TT | 1 |
| Sánchez-Lemus, E | 1 |
| Ozacmak, VH | 1 |
| Sayan, H | 1 |
| Cetin, A | 1 |
| Akyildiz-Igdem, A | 1 |
5 other studies available for candesartan and Acute Brain Injuries
| Article | Year |
|---|---|
AT 1 inhibition mediated neuroprotection after experimental traumatic brain injury is dependent on neutrophils in male mice.
Topics: Animals; Brain; Brain Injuries; Brain Injuries, Traumatic; Homeodomain Proteins; Inflammation; Male; | 2023 |
Candesartan attenuates ischemic brain edema and protects the blood-brain barrier integrity from ischemia/reperfusion injury in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood-Brain Ba | 2014 |
Neurorestoration after traumatic brain injury through angiotensin II receptor blockage.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Benzamides; Benzimidazoles; Benzoates; | 2015 |
Candesartan, an angiotensin II AT₁-receptor blocker and PPAR-γ agonist, reduces lesion volume and improves motor and memory function after traumatic brain injury in mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Brain Injuries | 2012 |
AT1 receptor blocker candesartan-induced attenuation of brain injury of rats subjected to chronic cerebral hypoperfusion.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; | 2007 |