Page last updated: 2024-08-22

camptothecin and Necrosis

camptothecin has been researched along with Necrosis in 47 studies

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (6.38)18.2507
2000's18 (38.30)29.6817
2010's24 (51.06)24.3611
2020's2 (4.26)2.80

Authors

AuthorsStudies
Büttner-Herold, M; Distel, L; Fietkau, R; Gottwald, D; Hecht, M; Hohmann, N; Putz, F1
Doğanlar, O; Doğanlar, ZB; Güçlü, O; Yüksel, V1
Albares, MP; del Carmen Leiva-Salinas, M; Frances, L; Guijarro, J; Ramon, R1
Jakubczak, M; Kontek, R; Matlawska-Wasowska, K1
Gilbert, CW; Hukuoka, Y; Kichikawa, K; Masada, T; Nishiofuku, H; Obayashi, C; Sato, T; Takano, M; Tanaka, T1
Alcocer-Gómez, E; Cordero, MD; Cotán, D; de la Mata, M; de Lavera, I; Fernández-Vega, A; Garrido-Maraver, J; Lema, R; Oropesa-Ávila, M; Pavón, AD; Paz, MV; Sánchez-Alcázar, JA; Zaderenko, AP1
Kaku, Y; Kanno, T; Nishizaki, T; Tsuchiya, A1
Gruenberger, B; Gruenberger, T; Singh, J; Starlinger, P; Stift, J; Stremitzer, S; Tamandl, D1
Almeida, GS; deSouza, NM; Jamin, Y; Papaevangelou, E; Robinson, SP1
Ghegediban, SH; Laurent, A; Maeda, N; Namur, J; Osuga, K; Paci, A; Pascale, F; Reb, P; Seck, A; Sterba, M; Verret, V; Wassef, M1
Elson, KM; Fisher, J; Fox, N; Hall, RM; Ingham, E; Kirkham, J; Tipper, JL1
Abrey, LE; Aftab, DT; Cloughesy, TF; Ellingson, BM; Harris, RJ; Hessel, C; Lai, A; Leu, K; Mason, WP; Nghiemphu, PL; Pope, WB; Sahebjam, S; Schwab, GM; Wen, PY; Woodworth, DC; Zaw, O1
Fukuoka, Y; Kichikawa, K; Masada, T; Matsushima, S; Nishiofuku, H; Ohbayashi, C; Sato, T; Sho, M; Takano, M; Tanaka, T; Tatsumoto, S; Yamato, I; Yasuda, S1
Grasso, F; Han, SH; Han, YS; Kim, IS; Kim, J; Tran, AHV1
Arumugam, P; Ki, J; Samson, A; Song, JM1
Amano, F; Kanai-Mori, A; Koike, A; Morishige, Y; Tamaki, R; Yanagihara, K1
Bielawska, A; Bielawski, K; Drozdowska, D; Gudej, J; Tomczyk, M1
Fritsch, G; Geyeregger, R; Printz, D; Stemberger, J; Witt, V1
Brugge, W; Cizginer, S; Kambadakone, A; Karaca, C; Konuk, Y; Macfarlane, C; Mino-Kenudson, M; Sahani, DV; Turner, BG1
Falcoz, PE; Massard, G; Renaud, S; Santelmo, N1
Azzariti, A; Cantore, M; Cassano, G; Colabufo, NA; Gasparre, G; Iannelli, G; Panaro, MA; Paradiso, A; Porcelli, L; Quatrale, AE; Tommasi, S1
Feng, G; Liang, B; Liang, H; Qian, J; Wang, Y; Zhao, H; Zheng, C1
Brinker, T; Glage, S; Hedrich, HJ; Held, N; Lewis, AL1
Fourcade, S; Gaudy-Marqueste, C; Grob, JJ; Richard, MA; Tasei, AM1
Chen, G; Feng, JM; He, JX; Huan, XJ; Jiang, Y; Li, JX; Li, XH; Miao, ZH; Wang, W; Wang, YQ; Xu, L; Yu, B1
Allen, PJ; Bao, F; D'Angelica, MI; DeMatteo, RP; Fong, Y; Hernandez-Boussard, T; Jarnagin, WR; Kemeny, NE; Klimstra, DS; Poultsides, GA; Saltz, LB; Servais, EL; Shia, J1
Herbst, RS; Isobe, T; Itasaka, S; Jacoby, JJ; Koo, PJ; Morgensztern, D; O'Reilly, MS; Onn, A; Shibuya, K; Shintani, T; Wu, W1
Bergamaschi, A; Darzynkiewicz, Z; De Nicola, M; Ghibelli, L; Grabarek, J; Smolewski, P; Teodori, L1
Chan, PJ; Jacobson, JD; King, A; Patton, WC; Rowland, SC1
Carano, RA; Koeppen, H; Ross, AL; Ross, J; Schwall, RH; Van Bruggen, N; Williams, SP1
Ishii, T; Matsuse, T; Teramoto, S1
Goldstein, NB; Norris, DA; Ribble, D; Shellman, YG1
Bhonde, MR; Daniel, PT; Gillissen, BF; Hanski, C; Hanski, ML; Notter, M; Zeitz, M1
Biasco, G; Brandi, G; Bridonneau, C; Dabard, J; De Vivo, A; Di Battista, M; Morselli Labate, AM; Pantaleo, MA; Pisi, AM; Raibaud, P1
He, F; Liang, PY; Lin, Y; Wang, T; Xing, FY; Zeng, YY; Zhao, JX1
Berrocal, DH; Gelpi, RJ; González, GE; Grinfeld, LR; Morales, C1
Horváth, V; Ondrousková, E; Smarda, J; Soucek, K1
Bar-Eli, M; Fan, D; Fidler, IJ; Kerbel, RS; Kim, SJ; Kuwai, T; Nakamura, T; Sasaki, T; Villares, GJ; Wang, H; Zigler, M1
Cotter, TG; Fernandes, RS1
Bertrand, R; Sané, AT1
Barbier, M; Boutonnat, J; Grunwald, D; Mousseau, M; Muirhead, K; Ronot, X; Seigneurin, D1
Bradbury, DA; Crouch, SP; Simmons, TD; Slater, KJ1
Kong, JY; Rabkin, SW1
Aller, P; de Blas, E; Fernández, C; Sancho, P; Troyano, A1
Hradcová, M; Marinov, I; Nemcová, J; Novák, JT; Stöckbauer, P1
Ng, CE; Quto b, SS1
Cotter, TG1

Reviews

1 review(s) available for camptothecin and Necrosis

ArticleYear
Induction of apoptosis in cells of the immune system by cytotoxic stimuli.
    Seminars in immunology, 1992, Volume: 4, Issue:6

    Topics: Animals; Aphidicolin; Apoptosis; Camptothecin; Cell Cycle; Dactinomycin; Humans; Immune System; Necrosis

1992

Trials

2 trial(s) available for camptothecin and Necrosis

ArticleYear
Histological response, pattern of tumor destruction and clinical outcome after neoadjuvant chemotherapy including bevacizumab or cetuximab in patients undergoing liver resection for colorectal liver metastases.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2015, Volume: 41, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Hepatectomy; Humans; Irinotecan; Kaplan-Meier Estimate; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Necrosis; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Proportional Hazards Models; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Tomography, X-Ray Computed; Treatment Outcome

2015
Baseline pretreatment contrast enhancing tumor volume including central necrosis is a prognostic factor in recurrent glioblastoma: evidence from single and multicenter trials.
    Neuro-oncology, 2017, Volume: 19, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Brain Neoplasms; Camptothecin; Contrast Media; Female; Follow-Up Studies; Glioblastoma; Humans; Irinotecan; Male; Middle Aged; Molecular Imaging; Necrosis; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Retrospective Studies; Survival Rate; Tumor Burden

2017

Other Studies

44 other study(ies) available for camptothecin and Necrosis

ArticleYear
Role of tumor cell senescence in non-professional phagocytosis and cell-in-cell structure formation.
    BMC molecular and cell biology, 2020, Nov-07, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Cadherins; Camptothecin; Cell Line, Tumor; Cell Survival; Cell-in-Cell Formation; Cellular Senescence; Cohort Studies; Female; Fibroblasts; Heat-Shock Response; Histones; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Methylation; Middle Aged; Necrosis; Phagocytosis; Prognosis; Rectal Neoplasms

2020
FOLFIRI-Mediated Toxicity in Human Aortic Smooth Muscle Cells and Possible Amelioration with Curcumin and Quercetin.
    Cardiovascular toxicology, 2020, Volume: 20, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aorta; Apoptosis; Apoptosis Regulatory Proteins; Camptothecin; Cells, Cultured; Curcumin; DNA Damage; Fluorouracil; Humans; Leucovorin; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Necrosis; Oxidative Stress; Quercetin; Signal Transduction

2020
Localized skin necrosis by bevacizumab.
    European journal of dermatology : EJD, 2013, Apr-01, Volume: 23, Issue:2

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Bevacizumab; Brain Neoplasms; Camptothecin; Drug Eruptions; Humans; Irinotecan; Male; Middle Aged; Necrosis; Skin

2013
The antioxidants, vitamin A and E but not vitamin C and melatonin enhance the proapoptotic effects of irinotecan in cancer cells in vitro.
    Toxicology in vitro : an international journal published in association with BIBRA, 2014, Volume: 28, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Ascorbic Acid; Camptothecin; Cell Line, Tumor; Coloring Agents; Flow Cytometry; HT29 Cells; Humans; In Situ Nick-End Labeling; Irinotecan; Melatonin; Necrosis; Vitamin A; Vitamin E

2014
Pharmacokinetics and antitumor efficacy of chemoembolization using 40 µm irinotecan-loaded microspheres in a rabbit liver tumor model.
    Journal of vascular and interventional radiology : JVIR, 2014, Volume: 25, Issue:7

    Topics: Alkaline Phosphatase; Animals; Antineoplastic Agents, Phytogenic; Aspartate Aminotransferases; Camptothecin; Chemistry, Pharmaceutical; Chemoembolization, Therapeutic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Monitoring; Irinotecan; Liver Neoplasms, Experimental; Microspheres; Necrosis; Particle Size; Rabbits

2014
Apoptotic cells subjected to cold/warming exposure disorganize apoptotic microtubule network and undergo secondary necrosis.
    Apoptosis : an international journal on programmed cell death, 2014, Volume: 19, Issue:9

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Calcium; Camptothecin; Caspases; Cell Line, Tumor; Cell Membrane; Cell Membrane Permeability; Cold Temperature; Hot Temperature; Humans; Macrophages; Membrane Proteins; Microtubules; Necrosis; Oligopeptides; Paclitaxel; Phosphatidylserines

2014
Irinotecan induces cell cycle arrest, but not apoptosis or necrosis, in Caco-2 and CW2 colorectal cancer cell lines.
    Pharmacology, 2015, Volume: 95, Issue:3-4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Caco-2 Cells; Camptothecin; Cell Cycle Checkpoints; Cell Line, Tumor; Humans; Irinotecan; Male; Mice, Nude; Necrosis; Neoplasms; Tumor Burden

2015
Diffusion-weighted MRI for imaging cell death after cytotoxic or apoptosis-inducing therapy.
    British journal of cancer, 2015, Apr-28, Volume: 112, Issue:9

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Camptothecin; Cell Proliferation; Colorectal Neoplasms; Diffusion Magnetic Resonance Imaging; Dipeptides; Female; Humans; Immunoenzyme Techniques; Indoles; Irinotecan; Lymphatic Metastasis; Mice; Mice, Nude; Necrosis; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2015
Safety and efficacy compared between irinotecan-loaded microspheres HepaSphere and DC bead in a model of VX2 liver metastases in the rabbit.
    Journal of vascular and interventional radiology : JVIR, 2015, Volume: 26, Issue:7

    Topics: Activation, Metabolic; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Chemoembolization, Therapeutic; Drug Carriers; Gene Expression Regulation, Neoplastic; Hepatic Artery; Injections, Intra-Arterial; Irinotecan; Liver Neoplasms, Experimental; Male; Microspheres; Necrosis; Particle Size; Rabbits; Tissue Distribution

2015
Non-destructive monitoring of viability in an ex vivo organ culture model of osteochondral tissue.
    European cells & materials, 2015, Jun-30, Volume: 29

    Topics: Alkaline Phosphatase; Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cartilage, Articular; Cell Survival; Culture Media, Conditioned; Detergents; Femur; Glucose; Glycosaminoglycans; L-Lactate Dehydrogenase; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Models, Biological; Necrosis; Octoxynol; Organ Culture Techniques; Swine; Time Factors

2015
Intraarterial Therapy Using Micellar Nanoparticles Incorporating SN-38 in a Rabbit Liver Tumor Model.
    Journal of vascular and interventional radiology : JVIR, 2017, Volume: 28, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Area Under Curve; Camptothecin; Drug Carriers; Drug Compounding; Female; Femoral Vein; Hepatic Artery; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Liver Neoplasms, Experimental; Micelles; Nanoparticles; Necrosis; Rabbits; Tissue Distribution

2017
MutY DNA Glycosylase Protects Cells From Tumor Necrosis Factor Alpha-Induced Necroptosis.
    Journal of cellular biochemistry, 2017, Volume: 118, Issue:7

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Blotting, Western; Camptothecin; Caspase 8; Cell Line; Cells, Cultured; DNA Glycosylases; Fluorescent Antibody Technique; Immunoprecipitation; Mice; Necrosis; Protein Binding; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; TNF Receptor-Associated Death Domain Protein; Tumor Necrosis Factor-alpha

2017
Knockdown of clusterin alters mitochondrial dynamics, facilitates necrosis in camptothecin-induced cancer stem cells.
    Cell biology and toxicology, 2017, Volume: 33, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Cell Line, Tumor; Clusterin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Mitochondrial Dynamics; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Necrosis; Neoplastic Stem Cells

2017
Effects of 5-fluorouracil, adriamycin and irinotecan on HSC-39, a human scirrhous gastric cancer cell line.
    Oncology reports, 2017, Volume: 37, Issue:4

    Topics: Adenocarcinoma, Scirrhous; Apoptosis; Camptothecin; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Necrosis; Reactive Oxygen Species; Stomach Neoplasms

2017
Human DNA topoisomerase inhibitors from Potentilla argentea and their cytotoxic effect against MCF-7.
    Die Pharmazie, 2008, Volume: 63, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzopyrans; Camptothecin; Cell Line, Tumor; DNA; DNA, Neoplasm; Enzyme Inhibitors; Ethidium; Female; Flavonoids; Humans; Necrosis; Poly dA-dT; Poly G; Potentilla; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

2008
Novel single-platform multiparameter FCM analysis of apoptosis: Significant differences between wash and no-wash procedure.
    Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2010, Volume: 77, Issue:11

    Topics: Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Count; Cell Separation; Flow Cytometry; Humans; Jurkat Cells; Leukemia, T-Cell; Necrosis; Photopheresis; Reproducibility of Results; Solutions

2010
Feasibility of EUS-guided injection of irinotecan-loaded microspheres into the swine pancreas.
    Gastrointestinal endoscopy, 2011, Volume: 73, Issue:3

    Topics: Animals; Camptothecin; Feasibility Studies; Injections; Irinotecan; Microspheres; Necrosis; Pancreas; Swine; Tomography, X-Ray Computed; Topoisomerase I Inhibitors; Ultrasonography, Interventional

2011
Mediastinal infusion with tracheal necrosis: an unusual complication of Port-a-cath devices.
    Interactive cardiovascular and thoracic surgery, 2011, Volume: 12, Issue:6

    Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Bronchoscopy; Camptothecin; Catheters, Indwelling; Equipment Design; Equipment Failure; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Middle Aged; Necrosis; Sigmoid Neoplasms; Surgical Flaps; Thoracotomy; Tomography, X-Ray Computed; Trachea; Tracheal Diseases

2011
MC70 potentiates doxorubicin efficacy in colon and breast cancer in vitro treatment.
    European journal of pharmacology, 2011, Nov-16, Volume: 670, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biphenyl Compounds; Breast Neoplasms; Camptothecin; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neoplasms; Doxorubicin; Drug Synergism; Female; Genomics; Humans; Irinotecan; Kinetics; Multidrug Resistance-Associated Proteins; Necrosis; Neoplasm Proteins; Signal Transduction; Tetrahydroisoquinolines; Topotecan

2011
Hepatocellular necrosis, apoptosis, and proliferation after transcatheter arterial embolization or chemoembolization in a standardized rabbit model.
    Journal of vascular and interventional radiology : JVIR, 2011, Volume: 22, Issue:11

    Topics: Alanine Transaminase; Angiography, Digital Subtraction; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Aspartate Aminotransferases; Camptothecin; Carcinoma, Hepatocellular; Cell Proliferation; Chemoembolization, Therapeutic; Embolization, Therapeutic; Hepatic Artery; In Situ Nick-End Labeling; Iodized Oil; Ki-67 Antigen; Liver Function Tests; Liver Neoplasms, Experimental; Liver Regeneration; Magnetic Resonance Imaging; Necrosis; Polyvinyl Alcohol; Rabbits; Time Factors; Tomography, X-Ray Computed; Tumor Necrosis Factor-alpha

2011
A safety and toxicity assessment of the administration of multiple intracerebral injections of irinotecan or doxorubicin drug-eluting beads.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2011, Volume: 13, Issue:10

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin; Cats; Doxorubicin; Female; Glioma; Infusion Pumps, Implantable; Injections, Intraventricular; Irinotecan; Male; Microspheres; Necrosis; Safety; Treatment Outcome

2011
Localized skin necrosis of steroid-induced striae distensae: an unusual complication of bevacizumab and irinotecan therapy.
    Archives of dermatology, 2011, Volume: 147, Issue:10

    Topics: Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Camptothecin; Chemoradiotherapy; Fatal Outcome; Glioblastoma; Humans; Irinotecan; Male; Methylprednisolone Hemisuccinate; Necrosis; Skin; Striae Distensae

2011
Differential sensitivity of RIP3-proficient and deficient murine fibroblasts to camptothecin anticancer drugs.
    Acta pharmacologica Sinica, 2012, Volume: 33, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Fibroblasts; Mice; Necrosis; NIH 3T3 Cells; Receptor-Interacting Protein Serine-Threonine Kinases

2012
Pathologic response to preoperative chemotherapy in colorectal liver metastases: fibrosis, not necrosis, predicts outcome.
    Annals of surgical oncology, 2012, Volume: 19, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Female; Fibrosis; Hepatectomy; Humans; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Mucins; Multivariate Analysis; Necrosis; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Prognosis; Retrospective Studies; Single-Blind Method

2012
Evaluation of novel orthotopic nude mouse models for human small-cell lung cancer.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2013, Volume: 8, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Proliferation; Cisplatin; Etoposide; Humans; Irinotecan; Lung Neoplasms; Mice; Mice, Nude; Necrosis; Paclitaxel; Small Cell Lung Carcinoma; Tumor Cells, Cultured

2013
Exposure of cells to static magnetic field accelerates loss of integrity of plasma membrane during apoptosis.
    Cytometry, 2002, Nov-01, Volume: 49, Issue:3

    Topics: Apoptosis; Camptothecin; Cell Count; Cell Membrane; Cell Survival; Flow Cytometry; HL-60 Cells; Humans; Image Cytometry; Leukemia; Magnetics; Necrosis

2002
Dual fluorescence analysis of DNA apoptosis in sperm.
    American journal of obstetrics and gynecology, 2003, Volume: 188, Issue:5

    Topics: Apoptosis; Benzimidazoles; Camptothecin; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Dyes; Genistein; Humans; Male; Microscopy, Fluorescence; Necrosis; Propidium; Spermatozoa; Staining and Labeling

2003
Quantification of tumor tissue populations by multispectral analysis.
    Magnetic resonance in medicine, 2004, Volume: 51, Issue:3

    Topics: Adipose Tissue; Animals; Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Disease Models, Animal; fas Receptor; Female; Humans; Irinotecan; Ligands; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Mice; Mice, Nude; Necrosis; Neoplasm Transplantation; Remission Induction; Skin Neoplasms; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Topoisomerase I Inhibitors; Transplantation, Heterologous; Tumor Necrosis Factor-alpha

2004
GSTP1 affects chemoresistance against camptothecin in human lung adenocarcinoma cells.
    Cancer letters, 2004, Dec-08, Volume: 216, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Non-Small-Cell Lung; Down-Regulation; Drug Resistance, Neoplasm; Glutathione Transferase; Humans; Lung Neoplasms; Necrosis

2004
A simple technique for quantifying apoptosis in 96-well plates.
    BMC biotechnology, 2005, May-10, Volume: 5

    Topics: Acridine Orange; Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Biotechnology; Camptothecin; Caspase 3; Caspase 7; Caspases; Cell Adhesion; Cell Line, Tumor; Chromatin; Enzyme Inhibitors; Ethidium; False Positive Reactions; Fluorescent Dyes; Humans; In Situ Nick-End Labeling; Jurkat Cells; Necrosis; Time Factors

2005
Equivalent effect of DNA damage-induced apoptotic cell death or long-term cell cycle arrest on colon carcinoma cell proliferation and tumour growth.
    Oncogene, 2006, Jan-12, Volume: 25, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Camptothecin; Cell Cycle; Cell Proliferation; Colonic Neoplasms; DNA Damage; Female; Flow Cytometry; Humans; Irinotecan; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Necrosis; Ploidies; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2006
Intestinal microflora and digestive toxicity of irinotecan in mice.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Feb-15, Volume: 12, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cecum; Colon; Diarrhea; Dose-Response Relationship, Drug; Ileum; Intestinal Mucosa; Intestines; Irinotecan; Jejunum; Mice; Mice, Inbred C3H; Microscopy, Electron, Scanning; Necrosis; Specific Pathogen-Free Organisms; Survival Analysis; Time Factors

2006
[Change of mitochondria during apoptosis of HL-60 cells induced by camptothecine].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2006, Volume: 22, Issue:2

    Topics: Annexin A5; Apoptosis; Camptothecin; Cell Line, Tumor; Fluorescein-5-isothiocyanate; HL-60 Cells; Humans; Membrane Potential, Mitochondrial; Mitochondria; Necrosis

2006
Irinotecan-eluting stents inhibited neointimal proliferation in hypercholesterolemic rabbit aortas.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2006, Volume: 68, Issue:1

    Topics: Animals; Aorta, Abdominal; Atherosclerosis; Camptothecin; Cell Proliferation; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Carriers; Hypercholesterolemia; Inflammation; Irinotecan; Necrosis; Phosphorylcholine; Rabbits; Research Design; Stents; Tunica Intima

2006
Alternative pathways of programmed cell death are activated in cells with defective caspase-dependent apoptosis.
    Leukemia research, 2008, Volume: 32, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Autophagy; Blotting, Western; Camptothecin; Caspases; Cell Line, Transformed; Cell Transformation, Neoplastic; Chickens; Cycloheximide; Genes, myb; Humans; Microscopy, Fluorescence; Necrosis; Oxides; Signal Transduction; U937 Cells

2008
Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitors.
    Neoplasia (New York, N.Y.), 2008, Volume: 10, Issue:5

    Topics: Animals; Apoptosis; Blotting, Western; Camptothecin; Cecum; Cell Proliferation; Colonic Neoplasms; Drug Therapy, Combination; Endothelial Cells; Enzyme Inhibitors; ErbB Receptors; Humans; Immunoenzyme Techniques; In Situ Nick-End Labeling; Irinotecan; Lymphatic Metastasis; Male; Mice; Mice, Nude; Necrosis; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Receptor, ErbB-2; RNA, Small Interfering; Topoisomerase I Inhibitors; Transforming Growth Factor alpha

2008
Apoptosis or necrosis: intracellular levels of glutathione influence mode of cell death.
    Biochemical pharmacology, 1994, Aug-17, Volume: 48, Issue:4

    Topics: Alkylating Agents; Apoptosis; Camptothecin; Cell Death; Cell Line; Chlorambucil; Dactinomycin; DNA; Glutathione; Humans; Melphalan; Necrosis

1994
Caspase inhibition in camptothecin-treated U-937 cells is coupled with a shift from apoptosis to transient G1 arrest followed by necrotic cell death.
    Cancer research, 1999, Aug-01, Volume: 59, Issue:15

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Caspase Inhibitors; Cell Cycle Proteins; DNA Damage; DNA Fragmentation; DNA Repair; DNA Replication; DNA, Neoplasm; Enzyme Activation; Enzyme Inhibitors; G1 Phase; Gene Expression Regulation, Neoplastic; Humans; Necrosis; Neoplasm Proteins; Topoisomerase I Inhibitors; U937 Cells

1999
Response of chemosensitive and chemoresistant leukemic cell lines to drug therapy: simultaneous assessment of proliferation, apoptosis, and necrosis.
    Cytometry, 2000, Feb-15, Volume: 42, Issue:1

    Topics: Annexin A5; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Camptothecin; Cell Division; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescent Dyes; Humans; Irinotecan; Leukemia, Myeloid; Necrosis; Propidium; Tranexamic Acid; Tumor Cells, Cultured; Vincristine

2000
Measurement of the ADP:ATP ratio in human leukaemic cell lines can be used as an indicator of cell viability, necrosis and apoptosis.
    Journal of immunological methods, 2000, Jun-23, Volume: 240, Issue:1-2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Apoptosis; Camptothecin; Cell Death; Cell Survival; Dexamethasone; Energy Metabolism; HL-60 Cells; Humans; In Situ Nick-End Labeling; Jurkat Cells; Leukemia; Microscopy, Fluorescence; Necrosis; U937 Cells

2000
Angiotensin II does not induce apoptosis but rather prevents apoptosis in cardiomyocytes.
    Peptides, 2000, Volume: 21, Issue:8

    Topics: Angiotensin II; Animals; Animals, Newborn; Apoptosis; Camptothecin; Cell Nucleus; Cell Separation; Cells, Cultured; Chick Embryo; Culture Media, Serum-Free; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Heart; In Situ Nick-End Labeling; Mice; Myocardium; Necrosis; Propidium; Staurosporine; Tetrazolium Salts; Thiazoles; Time Factors

2000
Effect of glutathione depletion on antitumor drug toxicity (apoptosis and necrosis) in U-937 human promonocytic cells. The role of intracellular oxidation.
    The Journal of biological chemistry, 2001, Dec-14, Volume: 276, Issue:50

    Topics: Adenosine Triphosphate; Alkylating Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Buthionine Sulfoximine; Camptothecin; Cell Death; Cisplatin; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Doxorubicin; Enzyme Inhibitors; Etoposide; Flow Cytometry; Glutathione; Humans; Hydrogen Peroxide; Hypoxia; Immunoblotting; Melphalan; Membrane Potentials; Mitochondria; Monocytes; Necrosis; Nucleic Acid Synthesis Inhibitors; Oxygen; Radiation-Protective Agents; Reactive Oxygen Species; Spectrometry, Fluorescence; Time Factors; Topoisomerase I Inhibitors; U937 Cells

2001
Monoclonal antibody to human chronic myeloid leukemia cell line MOLM-7 specifically reacts with an antigen of apoptotic cells.
    Leukemia research, 2002, Volume: 26, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; DNA, Neoplasm; Female; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mice; Mice, Inbred BALB C; Multiple Myeloma; Necrosis; Propidium; Tumor Cells, Cultured

2002
Comparison of apoptotic, necrotic and clonogenic cell death and inhibition of cell growth following camptothecin and X-radiation treatment in a human melanoma and a human fibroblast cell line.
    Cancer chemotherapy and pharmacology, 2002, Volume: 49, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Death; Combined Modality Therapy; Fibroblasts; Humans; Melanoma; Necrosis; Stem Cells; Tumor Cells, Cultured; X-Rays

2002