camptothecin has been researched along with Necrosis in 47 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (6.38) | 18.2507 |
2000's | 18 (38.30) | 29.6817 |
2010's | 24 (51.06) | 24.3611 |
2020's | 2 (4.26) | 2.80 |
Authors | Studies |
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Büttner-Herold, M; Distel, L; Fietkau, R; Gottwald, D; Hecht, M; Hohmann, N; Putz, F | 1 |
Doğanlar, O; Doğanlar, ZB; Güçlü, O; Yüksel, V | 1 |
Albares, MP; del Carmen Leiva-Salinas, M; Frances, L; Guijarro, J; Ramon, R | 1 |
Jakubczak, M; Kontek, R; Matlawska-Wasowska, K | 1 |
Gilbert, CW; Hukuoka, Y; Kichikawa, K; Masada, T; Nishiofuku, H; Obayashi, C; Sato, T; Takano, M; Tanaka, T | 1 |
Alcocer-Gómez, E; Cordero, MD; Cotán, D; de la Mata, M; de Lavera, I; Fernández-Vega, A; Garrido-Maraver, J; Lema, R; Oropesa-Ávila, M; Pavón, AD; Paz, MV; Sánchez-Alcázar, JA; Zaderenko, AP | 1 |
Kaku, Y; Kanno, T; Nishizaki, T; Tsuchiya, A | 1 |
Gruenberger, B; Gruenberger, T; Singh, J; Starlinger, P; Stift, J; Stremitzer, S; Tamandl, D | 1 |
Almeida, GS; deSouza, NM; Jamin, Y; Papaevangelou, E; Robinson, SP | 1 |
Ghegediban, SH; Laurent, A; Maeda, N; Namur, J; Osuga, K; Paci, A; Pascale, F; Reb, P; Seck, A; Sterba, M; Verret, V; Wassef, M | 1 |
Elson, KM; Fisher, J; Fox, N; Hall, RM; Ingham, E; Kirkham, J; Tipper, JL | 1 |
Abrey, LE; Aftab, DT; Cloughesy, TF; Ellingson, BM; Harris, RJ; Hessel, C; Lai, A; Leu, K; Mason, WP; Nghiemphu, PL; Pope, WB; Sahebjam, S; Schwab, GM; Wen, PY; Woodworth, DC; Zaw, O | 1 |
Fukuoka, Y; Kichikawa, K; Masada, T; Matsushima, S; Nishiofuku, H; Ohbayashi, C; Sato, T; Sho, M; Takano, M; Tanaka, T; Tatsumoto, S; Yamato, I; Yasuda, S | 1 |
Grasso, F; Han, SH; Han, YS; Kim, IS; Kim, J; Tran, AHV | 1 |
Arumugam, P; Ki, J; Samson, A; Song, JM | 1 |
Amano, F; Kanai-Mori, A; Koike, A; Morishige, Y; Tamaki, R; Yanagihara, K | 1 |
Bielawska, A; Bielawski, K; Drozdowska, D; Gudej, J; Tomczyk, M | 1 |
Fritsch, G; Geyeregger, R; Printz, D; Stemberger, J; Witt, V | 1 |
Brugge, W; Cizginer, S; Kambadakone, A; Karaca, C; Konuk, Y; Macfarlane, C; Mino-Kenudson, M; Sahani, DV; Turner, BG | 1 |
Falcoz, PE; Massard, G; Renaud, S; Santelmo, N | 1 |
Azzariti, A; Cantore, M; Cassano, G; Colabufo, NA; Gasparre, G; Iannelli, G; Panaro, MA; Paradiso, A; Porcelli, L; Quatrale, AE; Tommasi, S | 1 |
Feng, G; Liang, B; Liang, H; Qian, J; Wang, Y; Zhao, H; Zheng, C | 1 |
Brinker, T; Glage, S; Hedrich, HJ; Held, N; Lewis, AL | 1 |
Fourcade, S; Gaudy-Marqueste, C; Grob, JJ; Richard, MA; Tasei, AM | 1 |
Chen, G; Feng, JM; He, JX; Huan, XJ; Jiang, Y; Li, JX; Li, XH; Miao, ZH; Wang, W; Wang, YQ; Xu, L; Yu, B | 1 |
Allen, PJ; Bao, F; D'Angelica, MI; DeMatteo, RP; Fong, Y; Hernandez-Boussard, T; Jarnagin, WR; Kemeny, NE; Klimstra, DS; Poultsides, GA; Saltz, LB; Servais, EL; Shia, J | 1 |
Herbst, RS; Isobe, T; Itasaka, S; Jacoby, JJ; Koo, PJ; Morgensztern, D; O'Reilly, MS; Onn, A; Shibuya, K; Shintani, T; Wu, W | 1 |
Bergamaschi, A; Darzynkiewicz, Z; De Nicola, M; Ghibelli, L; Grabarek, J; Smolewski, P; Teodori, L | 1 |
Chan, PJ; Jacobson, JD; King, A; Patton, WC; Rowland, SC | 1 |
Carano, RA; Koeppen, H; Ross, AL; Ross, J; Schwall, RH; Van Bruggen, N; Williams, SP | 1 |
Ishii, T; Matsuse, T; Teramoto, S | 1 |
Goldstein, NB; Norris, DA; Ribble, D; Shellman, YG | 1 |
Bhonde, MR; Daniel, PT; Gillissen, BF; Hanski, C; Hanski, ML; Notter, M; Zeitz, M | 1 |
Biasco, G; Brandi, G; Bridonneau, C; Dabard, J; De Vivo, A; Di Battista, M; Morselli Labate, AM; Pantaleo, MA; Pisi, AM; Raibaud, P | 1 |
He, F; Liang, PY; Lin, Y; Wang, T; Xing, FY; Zeng, YY; Zhao, JX | 1 |
Berrocal, DH; Gelpi, RJ; González, GE; Grinfeld, LR; Morales, C | 1 |
Horváth, V; Ondrousková, E; Smarda, J; Soucek, K | 1 |
Bar-Eli, M; Fan, D; Fidler, IJ; Kerbel, RS; Kim, SJ; Kuwai, T; Nakamura, T; Sasaki, T; Villares, GJ; Wang, H; Zigler, M | 1 |
Cotter, TG; Fernandes, RS | 1 |
Bertrand, R; Sané, AT | 1 |
Barbier, M; Boutonnat, J; Grunwald, D; Mousseau, M; Muirhead, K; Ronot, X; Seigneurin, D | 1 |
Bradbury, DA; Crouch, SP; Simmons, TD; Slater, KJ | 1 |
Kong, JY; Rabkin, SW | 1 |
Aller, P; de Blas, E; Fernández, C; Sancho, P; Troyano, A | 1 |
Hradcová, M; Marinov, I; Nemcová, J; Novák, JT; Stöckbauer, P | 1 |
Ng, CE; Quto b, SS | 1 |
Cotter, TG | 1 |
1 review(s) available for camptothecin and Necrosis
Article | Year |
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Induction of apoptosis in cells of the immune system by cytotoxic stimuli.
Topics: Animals; Aphidicolin; Apoptosis; Camptothecin; Cell Cycle; Dactinomycin; Humans; Immune System; Necrosis | 1992 |
2 trial(s) available for camptothecin and Necrosis
Article | Year |
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Histological response, pattern of tumor destruction and clinical outcome after neoadjuvant chemotherapy including bevacizumab or cetuximab in patients undergoing liver resection for colorectal liver metastases.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Hepatectomy; Humans; Irinotecan; Kaplan-Meier Estimate; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Necrosis; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Proportional Hazards Models; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Tomography, X-Ray Computed; Treatment Outcome | 2015 |
Baseline pretreatment contrast enhancing tumor volume including central necrosis is a prognostic factor in recurrent glioblastoma: evidence from single and multicenter trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Brain Neoplasms; Camptothecin; Contrast Media; Female; Follow-Up Studies; Glioblastoma; Humans; Irinotecan; Male; Middle Aged; Molecular Imaging; Necrosis; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Retrospective Studies; Survival Rate; Tumor Burden | 2017 |
44 other study(ies) available for camptothecin and Necrosis
Article | Year |
---|---|
Role of tumor cell senescence in non-professional phagocytosis and cell-in-cell structure formation.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Cadherins; Camptothecin; Cell Line, Tumor; Cell Survival; Cell-in-Cell Formation; Cellular Senescence; Cohort Studies; Female; Fibroblasts; Heat-Shock Response; Histones; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Methylation; Middle Aged; Necrosis; Phagocytosis; Prognosis; Rectal Neoplasms | 2020 |
FOLFIRI-Mediated Toxicity in Human Aortic Smooth Muscle Cells and Possible Amelioration with Curcumin and Quercetin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aorta; Apoptosis; Apoptosis Regulatory Proteins; Camptothecin; Cells, Cultured; Curcumin; DNA Damage; Fluorouracil; Humans; Leucovorin; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Necrosis; Oxidative Stress; Quercetin; Signal Transduction | 2020 |
Localized skin necrosis by bevacizumab.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Bevacizumab; Brain Neoplasms; Camptothecin; Drug Eruptions; Humans; Irinotecan; Male; Middle Aged; Necrosis; Skin | 2013 |
The antioxidants, vitamin A and E but not vitamin C and melatonin enhance the proapoptotic effects of irinotecan in cancer cells in vitro.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Ascorbic Acid; Camptothecin; Cell Line, Tumor; Coloring Agents; Flow Cytometry; HT29 Cells; Humans; In Situ Nick-End Labeling; Irinotecan; Melatonin; Necrosis; Vitamin A; Vitamin E | 2014 |
Pharmacokinetics and antitumor efficacy of chemoembolization using 40 µm irinotecan-loaded microspheres in a rabbit liver tumor model.
Topics: Alkaline Phosphatase; Animals; Antineoplastic Agents, Phytogenic; Aspartate Aminotransferases; Camptothecin; Chemistry, Pharmaceutical; Chemoembolization, Therapeutic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Monitoring; Irinotecan; Liver Neoplasms, Experimental; Microspheres; Necrosis; Particle Size; Rabbits | 2014 |
Apoptotic cells subjected to cold/warming exposure disorganize apoptotic microtubule network and undergo secondary necrosis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Calcium; Camptothecin; Caspases; Cell Line, Tumor; Cell Membrane; Cell Membrane Permeability; Cold Temperature; Hot Temperature; Humans; Macrophages; Membrane Proteins; Microtubules; Necrosis; Oligopeptides; Paclitaxel; Phosphatidylserines | 2014 |
Irinotecan induces cell cycle arrest, but not apoptosis or necrosis, in Caco-2 and CW2 colorectal cancer cell lines.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Caco-2 Cells; Camptothecin; Cell Cycle Checkpoints; Cell Line, Tumor; Humans; Irinotecan; Male; Mice, Nude; Necrosis; Neoplasms; Tumor Burden | 2015 |
Diffusion-weighted MRI for imaging cell death after cytotoxic or apoptosis-inducing therapy.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Camptothecin; Cell Proliferation; Colorectal Neoplasms; Diffusion Magnetic Resonance Imaging; Dipeptides; Female; Humans; Immunoenzyme Techniques; Indoles; Irinotecan; Lymphatic Metastasis; Mice; Mice, Nude; Necrosis; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2015 |
Safety and efficacy compared between irinotecan-loaded microspheres HepaSphere and DC bead in a model of VX2 liver metastases in the rabbit.
Topics: Activation, Metabolic; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Chemoembolization, Therapeutic; Drug Carriers; Gene Expression Regulation, Neoplastic; Hepatic Artery; Injections, Intra-Arterial; Irinotecan; Liver Neoplasms, Experimental; Male; Microspheres; Necrosis; Particle Size; Rabbits; Tissue Distribution | 2015 |
Non-destructive monitoring of viability in an ex vivo organ culture model of osteochondral tissue.
Topics: Alkaline Phosphatase; Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cartilage, Articular; Cell Survival; Culture Media, Conditioned; Detergents; Femur; Glucose; Glycosaminoglycans; L-Lactate Dehydrogenase; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Models, Biological; Necrosis; Octoxynol; Organ Culture Techniques; Swine; Time Factors | 2015 |
Intraarterial Therapy Using Micellar Nanoparticles Incorporating SN-38 in a Rabbit Liver Tumor Model.
Topics: Animals; Antineoplastic Agents; Apoptosis; Area Under Curve; Camptothecin; Drug Carriers; Drug Compounding; Female; Femoral Vein; Hepatic Artery; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Liver Neoplasms, Experimental; Micelles; Nanoparticles; Necrosis; Rabbits; Tissue Distribution | 2017 |
MutY DNA Glycosylase Protects Cells From Tumor Necrosis Factor Alpha-Induced Necroptosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Blotting, Western; Camptothecin; Caspase 8; Cell Line; Cells, Cultured; DNA Glycosylases; Fluorescent Antibody Technique; Immunoprecipitation; Mice; Necrosis; Protein Binding; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; TNF Receptor-Associated Death Domain Protein; Tumor Necrosis Factor-alpha | 2017 |
Knockdown of clusterin alters mitochondrial dynamics, facilitates necrosis in camptothecin-induced cancer stem cells.
Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Cell Line, Tumor; Clusterin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Mitochondrial Dynamics; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Necrosis; Neoplastic Stem Cells | 2017 |
Effects of 5-fluorouracil, adriamycin and irinotecan on HSC-39, a human scirrhous gastric cancer cell line.
Topics: Adenocarcinoma, Scirrhous; Apoptosis; Camptothecin; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Necrosis; Reactive Oxygen Species; Stomach Neoplasms | 2017 |
Human DNA topoisomerase inhibitors from Potentilla argentea and their cytotoxic effect against MCF-7.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzopyrans; Camptothecin; Cell Line, Tumor; DNA; DNA, Neoplasm; Enzyme Inhibitors; Ethidium; Female; Flavonoids; Humans; Necrosis; Poly dA-dT; Poly G; Potentilla; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 2008 |
Novel single-platform multiparameter FCM analysis of apoptosis: Significant differences between wash and no-wash procedure.
Topics: Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Count; Cell Separation; Flow Cytometry; Humans; Jurkat Cells; Leukemia, T-Cell; Necrosis; Photopheresis; Reproducibility of Results; Solutions | 2010 |
Feasibility of EUS-guided injection of irinotecan-loaded microspheres into the swine pancreas.
Topics: Animals; Camptothecin; Feasibility Studies; Injections; Irinotecan; Microspheres; Necrosis; Pancreas; Swine; Tomography, X-Ray Computed; Topoisomerase I Inhibitors; Ultrasonography, Interventional | 2011 |
Mediastinal infusion with tracheal necrosis: an unusual complication of Port-a-cath devices.
Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Bronchoscopy; Camptothecin; Catheters, Indwelling; Equipment Design; Equipment Failure; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Middle Aged; Necrosis; Sigmoid Neoplasms; Surgical Flaps; Thoracotomy; Tomography, X-Ray Computed; Trachea; Tracheal Diseases | 2011 |
MC70 potentiates doxorubicin efficacy in colon and breast cancer in vitro treatment.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biphenyl Compounds; Breast Neoplasms; Camptothecin; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neoplasms; Doxorubicin; Drug Synergism; Female; Genomics; Humans; Irinotecan; Kinetics; Multidrug Resistance-Associated Proteins; Necrosis; Neoplasm Proteins; Signal Transduction; Tetrahydroisoquinolines; Topotecan | 2011 |
Hepatocellular necrosis, apoptosis, and proliferation after transcatheter arterial embolization or chemoembolization in a standardized rabbit model.
Topics: Alanine Transaminase; Angiography, Digital Subtraction; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Aspartate Aminotransferases; Camptothecin; Carcinoma, Hepatocellular; Cell Proliferation; Chemoembolization, Therapeutic; Embolization, Therapeutic; Hepatic Artery; In Situ Nick-End Labeling; Iodized Oil; Ki-67 Antigen; Liver Function Tests; Liver Neoplasms, Experimental; Liver Regeneration; Magnetic Resonance Imaging; Necrosis; Polyvinyl Alcohol; Rabbits; Time Factors; Tomography, X-Ray Computed; Tumor Necrosis Factor-alpha | 2011 |
A safety and toxicity assessment of the administration of multiple intracerebral injections of irinotecan or doxorubicin drug-eluting beads.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin; Cats; Doxorubicin; Female; Glioma; Infusion Pumps, Implantable; Injections, Intraventricular; Irinotecan; Male; Microspheres; Necrosis; Safety; Treatment Outcome | 2011 |
Localized skin necrosis of steroid-induced striae distensae: an unusual complication of bevacizumab and irinotecan therapy.
Topics: Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Camptothecin; Chemoradiotherapy; Fatal Outcome; Glioblastoma; Humans; Irinotecan; Male; Methylprednisolone Hemisuccinate; Necrosis; Skin; Striae Distensae | 2011 |
Differential sensitivity of RIP3-proficient and deficient murine fibroblasts to camptothecin anticancer drugs.
Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Fibroblasts; Mice; Necrosis; NIH 3T3 Cells; Receptor-Interacting Protein Serine-Threonine Kinases | 2012 |
Pathologic response to preoperative chemotherapy in colorectal liver metastases: fibrosis, not necrosis, predicts outcome.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Female; Fibrosis; Hepatectomy; Humans; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Mucins; Multivariate Analysis; Necrosis; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Prognosis; Retrospective Studies; Single-Blind Method | 2012 |
Evaluation of novel orthotopic nude mouse models for human small-cell lung cancer.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Proliferation; Cisplatin; Etoposide; Humans; Irinotecan; Lung Neoplasms; Mice; Mice, Nude; Necrosis; Paclitaxel; Small Cell Lung Carcinoma; Tumor Cells, Cultured | 2013 |
Exposure of cells to static magnetic field accelerates loss of integrity of plasma membrane during apoptosis.
Topics: Apoptosis; Camptothecin; Cell Count; Cell Membrane; Cell Survival; Flow Cytometry; HL-60 Cells; Humans; Image Cytometry; Leukemia; Magnetics; Necrosis | 2002 |
Dual fluorescence analysis of DNA apoptosis in sperm.
Topics: Apoptosis; Benzimidazoles; Camptothecin; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Dyes; Genistein; Humans; Male; Microscopy, Fluorescence; Necrosis; Propidium; Spermatozoa; Staining and Labeling | 2003 |
Quantification of tumor tissue populations by multispectral analysis.
Topics: Adipose Tissue; Animals; Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Disease Models, Animal; fas Receptor; Female; Humans; Irinotecan; Ligands; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Mice; Mice, Nude; Necrosis; Neoplasm Transplantation; Remission Induction; Skin Neoplasms; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Topoisomerase I Inhibitors; Transplantation, Heterologous; Tumor Necrosis Factor-alpha | 2004 |
GSTP1 affects chemoresistance against camptothecin in human lung adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Non-Small-Cell Lung; Down-Regulation; Drug Resistance, Neoplasm; Glutathione Transferase; Humans; Lung Neoplasms; Necrosis | 2004 |
A simple technique for quantifying apoptosis in 96-well plates.
Topics: Acridine Orange; Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Biotechnology; Camptothecin; Caspase 3; Caspase 7; Caspases; Cell Adhesion; Cell Line, Tumor; Chromatin; Enzyme Inhibitors; Ethidium; False Positive Reactions; Fluorescent Dyes; Humans; In Situ Nick-End Labeling; Jurkat Cells; Necrosis; Time Factors | 2005 |
Equivalent effect of DNA damage-induced apoptotic cell death or long-term cell cycle arrest on colon carcinoma cell proliferation and tumour growth.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Camptothecin; Cell Cycle; Cell Proliferation; Colonic Neoplasms; DNA Damage; Female; Flow Cytometry; Humans; Irinotecan; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Necrosis; Ploidies; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2006 |
Intestinal microflora and digestive toxicity of irinotecan in mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cecum; Colon; Diarrhea; Dose-Response Relationship, Drug; Ileum; Intestinal Mucosa; Intestines; Irinotecan; Jejunum; Mice; Mice, Inbred C3H; Microscopy, Electron, Scanning; Necrosis; Specific Pathogen-Free Organisms; Survival Analysis; Time Factors | 2006 |
[Change of mitochondria during apoptosis of HL-60 cells induced by camptothecine].
Topics: Annexin A5; Apoptosis; Camptothecin; Cell Line, Tumor; Fluorescein-5-isothiocyanate; HL-60 Cells; Humans; Membrane Potential, Mitochondrial; Mitochondria; Necrosis | 2006 |
Irinotecan-eluting stents inhibited neointimal proliferation in hypercholesterolemic rabbit aortas.
Topics: Animals; Aorta, Abdominal; Atherosclerosis; Camptothecin; Cell Proliferation; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Carriers; Hypercholesterolemia; Inflammation; Irinotecan; Necrosis; Phosphorylcholine; Rabbits; Research Design; Stents; Tunica Intima | 2006 |
Alternative pathways of programmed cell death are activated in cells with defective caspase-dependent apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Autophagy; Blotting, Western; Camptothecin; Caspases; Cell Line, Transformed; Cell Transformation, Neoplastic; Chickens; Cycloheximide; Genes, myb; Humans; Microscopy, Fluorescence; Necrosis; Oxides; Signal Transduction; U937 Cells | 2008 |
Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitors.
Topics: Animals; Apoptosis; Blotting, Western; Camptothecin; Cecum; Cell Proliferation; Colonic Neoplasms; Drug Therapy, Combination; Endothelial Cells; Enzyme Inhibitors; ErbB Receptors; Humans; Immunoenzyme Techniques; In Situ Nick-End Labeling; Irinotecan; Lymphatic Metastasis; Male; Mice; Mice, Nude; Necrosis; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Receptor, ErbB-2; RNA, Small Interfering; Topoisomerase I Inhibitors; Transforming Growth Factor alpha | 2008 |
Apoptosis or necrosis: intracellular levels of glutathione influence mode of cell death.
Topics: Alkylating Agents; Apoptosis; Camptothecin; Cell Death; Cell Line; Chlorambucil; Dactinomycin; DNA; Glutathione; Humans; Melphalan; Necrosis | 1994 |
Caspase inhibition in camptothecin-treated U-937 cells is coupled with a shift from apoptosis to transient G1 arrest followed by necrotic cell death.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Caspase Inhibitors; Cell Cycle Proteins; DNA Damage; DNA Fragmentation; DNA Repair; DNA Replication; DNA, Neoplasm; Enzyme Activation; Enzyme Inhibitors; G1 Phase; Gene Expression Regulation, Neoplastic; Humans; Necrosis; Neoplasm Proteins; Topoisomerase I Inhibitors; U937 Cells | 1999 |
Response of chemosensitive and chemoresistant leukemic cell lines to drug therapy: simultaneous assessment of proliferation, apoptosis, and necrosis.
Topics: Annexin A5; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Camptothecin; Cell Division; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescent Dyes; Humans; Irinotecan; Leukemia, Myeloid; Necrosis; Propidium; Tranexamic Acid; Tumor Cells, Cultured; Vincristine | 2000 |
Measurement of the ADP:ATP ratio in human leukaemic cell lines can be used as an indicator of cell viability, necrosis and apoptosis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Apoptosis; Camptothecin; Cell Death; Cell Survival; Dexamethasone; Energy Metabolism; HL-60 Cells; Humans; In Situ Nick-End Labeling; Jurkat Cells; Leukemia; Microscopy, Fluorescence; Necrosis; U937 Cells | 2000 |
Angiotensin II does not induce apoptosis but rather prevents apoptosis in cardiomyocytes.
Topics: Angiotensin II; Animals; Animals, Newborn; Apoptosis; Camptothecin; Cell Nucleus; Cell Separation; Cells, Cultured; Chick Embryo; Culture Media, Serum-Free; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Heart; In Situ Nick-End Labeling; Mice; Myocardium; Necrosis; Propidium; Staurosporine; Tetrazolium Salts; Thiazoles; Time Factors | 2000 |
Effect of glutathione depletion on antitumor drug toxicity (apoptosis and necrosis) in U-937 human promonocytic cells. The role of intracellular oxidation.
Topics: Adenosine Triphosphate; Alkylating Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Buthionine Sulfoximine; Camptothecin; Cell Death; Cisplatin; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Doxorubicin; Enzyme Inhibitors; Etoposide; Flow Cytometry; Glutathione; Humans; Hydrogen Peroxide; Hypoxia; Immunoblotting; Melphalan; Membrane Potentials; Mitochondria; Monocytes; Necrosis; Nucleic Acid Synthesis Inhibitors; Oxygen; Radiation-Protective Agents; Reactive Oxygen Species; Spectrometry, Fluorescence; Time Factors; Topoisomerase I Inhibitors; U937 Cells | 2001 |
Monoclonal antibody to human chronic myeloid leukemia cell line MOLM-7 specifically reacts with an antigen of apoptotic cells.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; DNA, Neoplasm; Female; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mice; Mice, Inbred BALB C; Multiple Myeloma; Necrosis; Propidium; Tumor Cells, Cultured | 2002 |
Comparison of apoptotic, necrotic and clonogenic cell death and inhibition of cell growth following camptothecin and X-radiation treatment in a human melanoma and a human fibroblast cell line.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Death; Combined Modality Therapy; Fibroblasts; Humans; Melanoma; Necrosis; Stem Cells; Tumor Cells, Cultured; X-Rays | 2002 |