Page last updated: 2024-08-22

camptothecin and Lymphoma

camptothecin has been researched along with Lymphoma in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.50)18.7374
1990's17 (42.50)18.2507
2000's13 (32.50)29.6817
2010's8 (20.00)24.3611
2020's1 (2.50)2.80

Authors

AuthorsStudies
Difilippantonio, S; Huang, SN; James, A; Marzi, L; Pommier, Y; Sun, Y1
Colcher, D; Jacobs, RE; Ng, TS; Procissi, D; Raubitschek, AA; Sohi, H; Wert, D1
Boku, N; Fujiki, T; Fujino, K; Gemma, A; Kakihata, K; Masatani, S; Morita, S; Shiozawa, T; Tadokoro, J1
Jin, J; Joo, KM; Kang, W; Kim, KH; Kim, SU; Lee, JI; Nam, DH; Seol, HJ; Yang, H1
Abraham, WD; Bustamante López, SC; Huang, B; Irvine, DJ; Luo, SS; Zheng, Y1
Adelman, CA; Borel, V; Boulton, SJ; Matsuzaki, K; Schindler, D1
Colcher, D; Davis, ME; Duringer, J; Forman, SJ; Kretzner, L; Numbenjapon, T; Raubitschek, A; Schluep, T; Wang, J; Yen, Y1
Burckhardt, G; Gupta, S; Hagos, Y; Henjakovic, M; Koepsell, H; Wulf, G1
Manabe, S; Matsumura, Y; Tarin, D; Yasunaga, M1
Kiguchi, T; Nakata, Y; Niiya, K; Shibakura, M; Tanimoto, M1
Aibe, H; Asayama, Y; Honda, H; Irie, H; Kakihara, D; Matake, K; Nakamura, K; Nakayama, T; Nishie, A; Ohga, S; Tajima, T; Yamamoto, N; Yoshimitsu, K1
Maeda, K; Okamura, S; Shibuya, T; Suzumiya, J; Suzushima, H; Tamura, K; Utsunomiya, A1
Innocenti, F; Mani, S; Prado, M; Ramírez, J; Ratain, MJ; Schilsky, RL; Undevia, SD; Vogelzang, NJ1
Anderson, KC; Burger, R; Catley, L; Chauhan, D; Denis, L; Hideshima, T; Munshi, NC; Podar, K; Richardson, P; Shringarpure, R; Son, MT; Tai, YT; Tassone, P1
Carlisle, R; Goetz, A; Kwiatek, J; Posey, JA; Rizzo, J; Rowinsky, EK; Rudoltz, MS; Saif, MW; Simmons, P; Stevenson, S; Takimoto, CH; Tolcher, AW1
Earnshaw, WC; Kaufmann, SH; Loegering, DA; Ruchaud, S1
Duncan, J; McLeod, HL; Scheffer, GL; Scheper, RJ; Shannon, WD; Zhang, W1
Akutsu, M; Furukawa, Y; Izumi, T; Kano, Y; Kobayashi, H; Mano, H; Tsunoda, S1
Booth, BP; Gobburu, JV; Ibrahim, A; Innocenti, F; Johnson, JR; Mehta, M; Rahman, A; Ramchandani, RP; Ratain, MJ; Wang, Y1
Adams, DJ; Giles, F; Jacobsen, TF; Myhren, F; Rizzieri, DA; Sandvold, ML1
Ariyoshi, Y; Ogawa, M1
Aboud, M; Aflalo, E; Benharroch, D; Chechelnitsky, G; Priel, E; Segal, S1
Pantazis, P1
Cheson, BD; Phillips, PH; Wilson, WH1
Ghetie, MA; Gordon, BE; Pantazis, P; Podar, EM; Uhr, JW; Vitetta, ES1
Kizaki, H; Onishi, Y1
Joshi, B; Li, L; Tang, DG; Zhu, Z1
Guan, LL; Lown, JW; Oreski, B; Zhao, R1
Kizaki, H; Oguro, M; Onishi, Y1
Cheson, BD; Elwood, P; Humphrey, R; Jaffe, ES; Kohler, DR; Little, R; Pearson, D; Steinberg, SM; Wilson, WH1
Hashimoto, S; Kizaki, H; Onishi, Y1
Rosen, LS1
Hunter, N; Meyn, RE; Mirkovic, N; Story, MD1
Smart, T1
Adams, DJ; Bass, AJ; Davis, P; DeCastro, CM; Foster, T; Gockerman, JP; Hammett, E; Moore, JO; Payne, N; Rizzieri, DA; Rosner, GL1
Allen, JW; Backer, LC; Campbell, JA; DeMarini, DM; Doerr, CL; Harrington-Brock, K; Howard, DR; Kligerman, AD; Moore, MM1
Arima, T; Ariyoshi, H; Ichimaru, M; Kuramoto, A; Masaoka, T; Oguro, M; Ohno, R; Okada, K; Sakai, Y; Yoshida, Y1
Drewinko, B; Freireich, EJ; Gottlieb, JA1

Reviews

3 review(s) available for camptothecin and Lymphoma

ArticleYear
[Clinical trials of new antitumor drugs in hematopoietic malignancies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21 Suppl 3

    Topics: Acute Disease; Antineoplastic Agents, Phytogenic; Camptothecin; Clinical Trials as Topic; Doxorubicin; Ethics, Medical; Humans; Idarubicin; Irinotecan; Leukemia; Lymphoma

1994
The water-insoluble camptothecin analogues: promising drugs for the effective treatment of haematological malignancies.
    Leukemia research, 1995, Volume: 19, Issue:11

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biotransformation; Camptothecin; Cell Differentiation; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Humans; Leukemia; Leukemia, Experimental; Lymphoma; Mice; Phosphorylation; Solubility; Topoisomerase I Inhibitors; Tumor Cells, Cultured

1995
Irinotecan in lymphoma, leukemia, and breast, pancreatic, ovarian, and small-cell lung cancers.
    Oncology (Williston Park, N.Y.), 1998, Volume: 12, Issue:8 Suppl 6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Carcinoma, Non-Small-Cell Lung; Female; Humans; Irinotecan; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms

1998

Trials

5 trial(s) available for camptothecin and Lymphoma

ArticleYear
Phase I study of the combination of irinotecan hydrochloride, carboplatin, and dexamethasone for the treatment of relapsed or refractory malignant lymphoma.
    International journal of hematology, 2004, Volume: 79, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Dexamethasone; Female; Humans; Irinotecan; Lymphoma; Male; Maximum Tolerated Dose; Middle Aged; Salvage Therapy; Treatment Outcome

2004
A phase I trial of pharmacologic modulation of irinotecan with cyclosporine and phenobarbital.
    Clinical pharmacology and therapeutics, 2004, Volume: 76, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Area Under Curve; Camptothecin; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Neoplasm; Drug Therapy, Combination; Endpoint Determination; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Half-Life; Humans; Hypnotics and Sedatives; Immunosuppressive Agents; Irinotecan; Lymphoma; Male; Middle Aged; Neoplasms; Phenobarbital

2004
Phase 1 study of weekly polyethylene glycol-camptothecin in patients with advanced solid tumors and lymphomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Nov-01, Volume: 11, Issue:21

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Camptothecin; Dose-Response Relationship, Drug; Female; Humans; Lymphoma; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Polyethylene Glycols; Time Factors

2005
Phase II and dose-escalation with or without granulocyte colony-stimulating factor study of 9-aminocamptothecin in relapsed and refractory lymphomas.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Camptothecin; Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Granulocyte Colony-Stimulating Factor; Humans; Infusions, Intravenous; Lymphoma; Male; Maximum Allowable Concentration; Middle Aged; Recurrence

1998
Phase I evaluation of prolonged-infusion gemcitabine with irinotecan for relapsed or refractory leukemia or lymphoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Jul-01, Volume: 20, Issue:13

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Camptothecin; Deoxycytidine; Drug Administration Schedule; Esophagitis; Evaluation Studies as Topic; Female; Gemcitabine; Humans; Infusions, Intravenous; Irinotecan; Leukemia; Lymphoma; Male; Middle Aged; Nausea; Neutropenia; Recurrence; Stomatitis; Treatment Outcome; Vomiting

2002

Other Studies

32 other study(ies) available for camptothecin and Lymphoma

ArticleYear
The Indenoisoquinoline LMP517: A Novel Antitumor Agent Targeting both TOP1 and TOP2.
    Molecular cancer therapeutics, 2020, Volume: 19, Issue:8

    Topics: Animals; Camptothecin; Carcinoma, Small Cell; Cell Line, Tumor; Chickens; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Etoposide; Female; Histones; Humans; Indans; Isoquinolines; Lung Neoplasms; Lymphoma; Mice; Mice, Nude; Molecular Targeted Therapy; Neoplasm Proteins; Poultry Diseases; Random Allocation; Recombinant Proteins; Substrate Specificity; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Xenograft Model Antitumor Assays

2020
Serial diffusion MRI to monitor and model treatment response of the targeted nanotherapy CRLX101.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, May-01, Volume: 19, Issue:9

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cyclodextrins; Diffusion Magnetic Resonance Imaging; Female; Humans; Lymphoma; Mice; Mice, Nude; Models, Biological; Nanomedicine; Treatment Outcome; Tumor Burden; Xenograft Model Antitumor Assays

2013
Risk factors for severe adverse effects and treatment-related deaths in Japanese patients treated with irinotecan-based chemotherapy: a postmarketing survey.
    Japanese journal of clinical oncology, 2013, Volume: 43, Issue:5

    Topics: Aged; Analysis of Variance; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Asian People; Breast Neoplasms; Camptothecin; Colorectal Neoplasms; Death; Diarrhea; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Irinotecan; Japan; Leukopenia; Logistic Models; Lung Neoplasms; Lymphoma; Male; Middle Aged; Neoplasms; Ovarian Neoplasms; Product Surveillance, Postmarketing; Risk Assessment; Risk Factors; Sex Factors; Skin Neoplasms; Stomach Neoplasms; Thrombocytopenia

2013
Genetically-engineered human neural stem cells with rabbit carboxyl esterase can target CNS lymphoma.
    Anticancer research, 2013, Volume: 33, Issue:12

    Topics: Animals; Antineoplastic Agents, Phytogenic; Base Sequence; Bystander Effect; Camptothecin; Carboxylesterase; Central Nervous System Neoplasms; DNA Primers; Genetic Engineering; Humans; Irinotecan; Lymphoma; Male; Mice; Mice, Inbred BALB C; Neural Stem Cells; Rabbits; Reverse Transcriptase Polymerase Chain Reaction

2013
Active targeting of chemotherapy to disseminated tumors using nanoparticle-carrying T cells.
    Science translational medicine, 2015, Jun-10, Volume: 7, Issue:291

    Topics: Animals; Antineoplastic Agents; Bystander Effect; Camptothecin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cytotoxicity, Immunologic; Drug Delivery Systems; Humans; Interleukin-2; Irinotecan; Lymph Nodes; Lymphoma; Mice; Nanocapsules; Nanoparticles; Receptors, Lymphocyte Homing; Sirolimus; T-Lymphocytes; Treatment Outcome

2015
Cellular backpackers deliver lymphoma drugs.
    Cancer discovery, 2015, Volume: 5, Issue:8

    Topics: Animals; Antineoplastic Agents; Camptothecin; Drug Delivery Systems; Humans; Irinotecan; Lymphoma; T-Lymphocytes

2015
FANCJ suppresses microsatellite instability and lymphomagenesis independent of the Fanconi anemia pathway.
    Genes & development, 2015, Dec-15, Volume: 29, Issue:24

    Topics: Animals; Antineoplastic Agents; Basic-Leucine Zipper Transcription Factors; Camptothecin; Cell Line; Cells, Cultured; DNA Damage; Fanconi Anemia; Fanconi Anemia Complementation Group D2 Protein; Fanconi Anemia Complementation Group Proteins; Female; Fibroblasts; Genetic Predisposition to Disease; Humans; Lymphoma; Male; Mice, Knockout; Microsatellite Instability; Mitomycin; Neoplasms, Glandular and Epithelial; RNA Helicases; Ultraviolet Rays

2015
Preclinical results of camptothecin-polymer conjugate (IT-101) in multiple human lymphoma xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jul-01, Volume: 15, Issue:13

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cyclodextrins; Female; Humans; Irinotecan; Lymphoma; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, SCID; Polymers; Topoisomerase I Inhibitors; Treatment Outcome; Xenograft Model Antitumor Assays

2009
Human organic cation transporter 1 is expressed in lymphoma cells and increases susceptibility to irinotecan and paclitaxel.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 341, Issue:1

    Topics: Animals; Camptothecin; Cell Line, Tumor; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Lymphoma; Organic Cation Transporter 1; Paclitaxel

2012
Tailored immunoconjugate therapy depending on a quantity of tumor stroma.
    Cancer science, 2013, Volume: 104, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Collagen; Female; Humans; Immunoconjugates; Irinotecan; Lymphoma; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Pancreatic Neoplasms; Topoisomerase I Inhibitors

2013
Camptothecin induces urokinase-type plasminogen activator gene-expression in human RC-K8 malignant lymphoma and H69 small cell lung cancer cells.
    Acta medica Okayama, 2002, Volume: 56, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Small Cell; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Lymphoma; RNA, Messenger; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

2002
[A case of isolated hepatic malignant lymphoma representing characteristic findings on radiological imaging].
    Fukuoka igaku zasshi = Hukuoka acta medica, 2003, Volume: 94, Issue:11

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Irinotecan; L-Lactate Dehydrogenase; Liver Neoplasms; Lymphoma; Magnetic Resonance Imaging; Male; Neoplasm Recurrence, Local; Prednisolone; Tomography, X-Ray Computed; Treatment Outcome; Vincristine

2003
Proteasomal degradation of topoisomerase I is preceded by c-Jun NH2-terminal kinase activation, Fas up-regulation, and poly(ADP-ribose) polymerase cleavage in SN38-mediated cytotoxicity against multiple myeloma.
    Cancer research, 2004, Dec-01, Volume: 64, Issue:23

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Marrow Cells; Boronic Acids; Bortezomib; Camptothecin; Cell Communication; Cell Line, Tumor; DNA Topoisomerases, Type I; DNA, Neoplasm; Doxorubicin; Drug Synergism; Enzyme Activation; fas Receptor; Humans; Irinotecan; JNK Mitogen-Activated Protein Kinases; Lymphoma; Multiple Myeloma; Poly(ADP-ribose) Polymerases; Proteasome Endopeptidase Complex; Pyrazines; Signal Transduction; Stromal Cells; Up-Regulation

2004
Evaluation of the role of caspase-6 in anticancer drug-induced apoptosis.
    Cell death and differentiation, 2006, Volume: 13, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Caspase 6; Caspases; Cell Line, Tumor; Chickens; Etoposide; Gene Expression Regulation, Neoplastic; Lymphoma

2006
Expression of drug pathway proteins is independent of tumour type.
    The Journal of pathology, 2006, Volume: 209, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Breast Neoplasms; Camptothecin; Colonic Neoplasms; Cytochrome P-450 Enzyme System; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Humans; Immunohistochemistry; Irinotecan; Lung Neoplasms; Lymphoma; Male; Melanoma; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Neoplasms; Ovarian Neoplasms; Prostatic Neoplasms; Tissue Array Analysis

2006
Cytotoxic effects of histone deacetylase inhibitor FK228 (depsipeptide, formally named FR901228) in combination with conventional anti-leukemia/lymphoma agents against human leukemia/lymphoma cell lines.
    Investigational new drugs, 2007, Volume: 25, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Benzamides; Camptothecin; Carboplatin; Cell Line, Tumor; Cell Survival; Cyclophosphamide; Cytarabine; Depsipeptides; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Imatinib Mesylate; Irinotecan; K562 Cells; Leukemia; Lymphoma; Mercaptopurine; Piperazines; Pyrimidines; Time Factors

2007
The role of SN-38 exposure, UGT1A1*28 polymorphism, and baseline bilirubin level in predicting severe irinotecan toxicity.
    Journal of clinical pharmacology, 2007, Volume: 47, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Area Under Curve; Bilirubin; Camptothecin; Female; Glucuronosyltransferase; Humans; Irinotecan; Lymphoma; Male; Models, Biological; Neutropenia; Polymorphism, Genetic; Regression Analysis

2007
Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells.
    Leukemia & lymphoma, 2008, Volume: 49, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Cytarabine; Deoxycytidine; Drug Interactions; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Hydrazines; Idarubicin; Irinotecan; Leukemia; Lymphoma; Sulfonamides; Topotecan

2008
Clinical trials referral resource. Clinical trials with 9-aminocamptothecin.
    Oncology (Williston Park, N.Y.), 1995, Volume: 9, Issue:8

    Topics: Antineoplastic Agents; Camptothecin; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Colonic Neoplasms; Humans; Lung Neoplasms; Lymphoma; Neutropenia

1995
Inhibition of retrovirus-induced disease in mice by camptothecin.
    Journal of virology, 1993, Volume: 67, Issue:6

    Topics: 3T3 Cells; Acute Disease; Animals; Animals, Newborn; Camptothecin; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Lymphoma; Mice; Mice, Inbred BALB C; Moloney murine leukemia virus; Neoplasms, Experimental; Retroviridae Infections; Spleen; Spleen Focus-Forming Viruses; Virus Replication

1993
Clinical trials at the medicine branch of the NCI-part 2.
    Oncology (Williston Park, N.Y.), 1995, Volume: 9, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Central Nervous System Neoplasms; Clinical Trials as Topic; Eye Neoplasms; Humans; Immunotherapy; Lymphoma; Lymphoma, Non-Hodgkin; Recurrence

1995
Combination immunotoxin treatment and chemotherapy in SCID mice with advanced, disseminated Daudi lymphoma.
    International journal of cancer, 1996, Sep-27, Volume: 68, Issue:1

    Topics: Animals; Antigens, CD; Antigens, CD19; Antigens, Differentiation, B-Lymphocyte; Antineoplastic Agents; Camptothecin; Cell Adhesion Molecules; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Immunotoxins; Lectins; Lymphoma; Mice; Mice, SCID; Ricin; Sialic Acid Binding Ig-like Lectin 2

1996
Molecular cloning of the genes suppressed in RVC lymphoma cells by topoisomerase inhibitors.
    Biochemical and biophysical research communications, 1996, Nov-01, Volume: 228, Issue:1

    Topics: Amino Acid Sequence; Animals; Antineoplastic Agents, Phytogenic; Base Sequence; Camptothecin; Cloning, Molecular; DNA, Neoplasm; Down-Regulation; Etoposide; Gene Expression Regulation, Neoplastic; Heterogeneous Nuclear Ribonucleoprotein A1; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Heterogeneous-Nuclear Ribonucleoproteins; Lymphoma; Mice; Molecular Sequence Data; Neoplasm Proteins; Radiation Leukemia Virus; Ribonucleoproteins; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1996
Apoptosis in the absence of cytochrome c accumulation in the cytosol.
    Biochemical and biophysical research communications, 1998, Jan-14, Volume: 242, Issue:2

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Biotin; Bleomycin; Blotting, Western; Camptothecin; Cytochrome c Group; Cytosol; Enzyme Inhibitors; Etoposide; Humans; Hydroxamic Acids; Lymphoma; Microscopy, Fluorescence; Mitochondria; Phalloidine; Poly(ADP-ribose) Polymerases; Staurosporine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vinblastine

1998
Synthesis, topoisomerase I inhibitory activity and in vitro cytotoxicity of camptothecin derivatives bearing five-membered heterocycle containing 10-substituents.
    Anti-cancer drug design, 1998, Volume: 13, Issue:2

    Topics: Animals; Antineoplastic Agents; Base Sequence; Camptothecin; DNA; DNA Topoisomerases, Type I; DNA, Superhelical; Electrophoresis; Enzyme Inhibitors; Humans; KB Cells; Lymphoma; Mice; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Structure-Activity Relationship; Topoisomerase I Inhibitors; Tumor Cells, Cultured

1998
4-Piperidinopiperidine-resistant lymphoma cells were resistant to dexamethasone- and A23187-induced apoptosis.
    Cancer letters, 1998, May-15, Volume: 127, Issue:1-2

    Topics: Apoptosis; Calcimycin; Camptothecin; Dexamethasone; DNA Fragmentation; Drug Resistance; Humans; Irinotecan; Lymphoma; Piperidines; Tumor Cells, Cultured

1998
Cloning of the TIS gene suppressed by topoisomerase inhibitors.
    Gene, 1998, Jul-30, Volume: 215, Issue:2

    Topics: Amino Acid Sequence; Animals; Apoptosis Regulatory Proteins; Base Sequence; Camptothecin; Cloning, Molecular; COS Cells; DNA, Complementary; Exons; Genes, Reporter; Genomic Library; Liver; Lymphoma; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Promoter Regions, Genetic; Protein Biosynthesis; Proteins; Recombinant Proteins; Restriction Mapping; RNA-Binding Proteins; Sequence Deletion; TATA Box; Topoisomerase I Inhibitors; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1998
Bcl-2 expression correlates with apoptosis induction but not tumor growth delay in transplantable murine lymphomas treated with different chemotherapy drugs.
    Cancer chemotherapy and pharmacology, 1999, Volume: 44, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Cisplatin; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Lymphoma; Male; Mice; Mice, Inbred C3H; Proto-Oncogene Proteins c-bcl-2

1999
Topotecan research moves forward at last.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:4

    Topics: Antineoplastic Agents; Antiviral Agents; Camptothecin; Clinical Trials as Topic; HIV Long Terminal Repeat; HIV-1; Humans; Leukoencephalopathy, Progressive Multifocal; Lymphoma; Mutation; Sarcoma, Kaposi; Topoisomerase I Inhibitors; Topotecan; Virus Replication

1995
Genotoxicity of inhibitors of DNA topoisomerases I (camptothecin) and II (m-AMSA) in vivo and in vitro.
    Mutagenesis, 1990, Volume: 5, Issue:6

    Topics: Amsacrine; Animals; Bone Marrow; Bone Marrow Cells; Camptothecin; Cell Line; Chromatids; Chromosome Aberrations; Dose-Response Relationship, Drug; Gene Rearrangement; In Vitro Techniques; Lymphocytes; Lymphoma; Male; Mice; Mice, Inbred C57BL; Mutagens; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1990
An early phase II study of CPT-11: a new derivative of camptothecin, for the treatment of leukemia and lymphoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Agents, Phytogenic; Camptothecin; Drug Evaluation; Female; Humans; Irinotecan; Leukemia; Lymphoma; Male; Middle Aged

1990
Lethal activity of camptothecin sodium on human lymphoma cells.
    Cancer research, 1974, Volume: 34, Issue:4

    Topics: Camptothecin; Cell Division; Cell Line; Cell Survival; Humans; Lymphoma; Time Factors

1974