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camptothecin and Leukemia P388

camptothecin has been researched along with Leukemia P388 in 34 studies

Research

Studies (34)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (14.71)	18.7374
1990's	18 (52.94)	18.2507
2000's	10 (29.41)	29.6817
2010's	1 (2.94)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gunatilaka, AA; Hoffmann, G; Johnson, RK; Kingston, DG; Samaranayake, G	1
Lindley, JT; Ronman, PE; Wall, ME; Wani, MC	1
Ejima, A; Kawato, Y; Matsumoto, K; Mitsui, I; Ohsuki, S; Sato, K; Sugimori, M; Tagawa, H; Uoto, K; Yasuoka, M	1
Bisagni, E; Croisy, A; Janin, YL; Riou, JF	1
Bodo, B; Cosson, JP; Jossang, A; Provost, J; Sévenet, T; Zahir, A	1
Ejima, A; Hirota, Y; Kawato, Y; Mitsui, I; Ohsuki, S; Sato, K; Sugimori, M; Terasawa, H; Uoto, K	1
Baguley, BC; Bu, X; Deady, LW; Denny, WA; Finlay, GJ	1
Choe, YH; Greenwald, RB; Wu, D	1
Fairchild, CR; Farnsworth, NR; Garcia, R; Graf, TN; Izydore, RA; Jiménez, F; Kim, NC; Kinghorn, AD; Kroll, DJ; Lee, D; Navarro, HA; Oberlies, NH; Phifer, SS; Rose, WC; Seo, EK; Soejarto, DD; Wall, ME; Wani, MC; Wild, R	1
Baltas, M; Bedos-Belval, F; Delomenède, M; Duran, H; Gornitzka, H; Negre-Salvayre, A; Rakotondramanana, DL; Rasoanaivo, P	1
Chrisafi, S; Digkas, E; Hatzimichail, A; Kareli, D; Lialiaris, T; Mantadakis, E; Passadaki, T; Vargemezis, V	1
Dupon, C; Gabut, M; Kohlhagen, G; Pommier, Y; Soret, J; Stévenin, J; Tazi, J	1
Antony, S; Gmeiner, WH; Kohlhagen, G; Liao, ZY; Pommier, Y; Sordet, O; Zhang, HL	1
Bailly, C; Beauvillain, JC; Cuevas, C; Gallego, MA; Kluza, J; Loyens, A; Marchetti, P; Sousa-Faro, JM	1
Creasey, WA; Gil, D; Richards, M; Tsou, KC	1
Funk, LR; Hofmann, GA; Johnson, RK; Mattern, MR; McCabe, FL; Polsky, RM	1
Comoe, L; Couprie, J; Desoize, B; Grondard, L; Jardillier, JC; Larsen, AK; Riou, JF	1
Kumi, R; Perez-Soler, R; Poirot, K; Reddy, S; Sugarman, SM; Wasan, K; Zou, Y	1
Choe, YH; Conover, CD; Gilbert, C; Greenwald, RB; Hsue, M; Lee, C; Martinez, A; Pendri, A; Wu, D; Xia, J	1
Dodds, HM; Haaz, MC; Riou, JF; Rivory, LP; Robert, J	1
Fukasawa, K; Komatani, H; Morita, M; Nishimura, S; Okura, A; Sakaizumi, N; Yoshida, E; Yoshinari, T	1
Bailly, C; Bigg, DC; Coulomb, H; Dassonneville, L; Demarquay, D; Huchet, M; Lansiaux, A; Lavergne, O	1
Bailly, C; Dassonneville, L; Facompré, M; Goossens, JF; Hénichart, JP	1
Karaberis, E; Mourelatos, D	1
Conover, CD; Greenwald, RB; Pendri, A; Shum, KL	1
Pommier, Y; Takebayashi, Y; Urasaki, Y	1
Ejima, A; Kawato, Y; Matsumoto, K; Ohsuki, S; Sugimori, M; Tagawa, H; Terasawa, H; Yasuoka, M	1
Aonuma, M; Hirota, Y; Kawato, Y; Kuga, H; Sato, K	1
Hofmann, GA; Johnson, RK; Mattern, MR; McCabe, FL	1
Ross, WE; Sullivan, DM	1
Eng, WK; Hertzberg, RP; Hofmann, GA; Johnson, RK; Mattern, MR; McCabe, FL; Tan, KB; Woessner, RD	1
Eng, WK; Johnson, RK; Mattern, MR; McCabe, FL; Tan, KB	1
Ejima, A; Kawato, Y; Matsumoto, K; Ohsuki, S; Sugimori, M; Tagawa, H; Terasawa, H	1
Matsushita, M; Matsuzaki, T; Saito, H; Tsuruo, T; Yokokura, T	1

Reviews

1 review(s) available for camptothecin and Leukemia P388

Article	Year
Resistance to inhibitors of DNA topoisomerases. Cancer treatment and research, 1991, Volume: 57 Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Camptothecin; Carrier Proteins; Cell Cycle; Cell Line; Cricetinae; Cricetulus; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Circular; DNA, Neoplasm; DNA, Single-Stranded; Drug Resistance; Humans; Intercalating Agents; Leukemia P388; Membrane Glycoproteins; Mice; Protein Binding; Subcellular Fractions; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors	1991

Article

Year

Resistance to inhibitors of DNA topoisomerases.

Cancer treatment and research, 1991, Volume: 57

Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Camptothecin; Carrier Proteins; Cell Cycle; Cell Line; Cricetinae; Cricetulus; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Circular; DNA, Neoplasm; DNA, Single-Stranded; Drug Resistance; Humans; Intercalating Agents; Leukemia P388; Membrane Glycoproteins; Mice; Protein Binding; Subcellular Fractions; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1991

Other Studies

33 other study(ies) available for camptothecin and Leukemia P388

Article	Year
Bioactive ergost-5-ene-3 beta, 7 alpha-diol derivatives from Pseudobersama mossambicensis. Journal of natural products, 1992, Volume: 55, Issue:11 Topics: Animals; Antineoplastic Agents, Phytogenic; DNA Repair; Drug Screening Assays, Antitumor; Ergosterol; Leukemia P388; Mice; Plants; Saccharomyces cerevisiae	1992
Plant antitumor agents. 18. Synthesis and biological activity of camptothecin analogues. Journal of medicinal chemistry, 1980, Volume: 23, Issue:5 Topics: Animals; Camptothecin; Cells, Cultured; Chemical Phenomena; Chemistry; Leukemia P388; Mice	1980
Antitumor agents. 7. Synthesis and antitumor activity of novel hexacyclic camptothecin analogues. Journal of medicinal chemistry, 1994, Sep-16, Volume: 37, Issue:19 Topics: Animals; Antineoplastic Agents; Camptothecin; Drug Screening Assays, Antitumor; Leukemia P388; Mice; Neoplasms, Experimental; Polycyclic Compounds; Structure-Activity Relationship; Tumor Cells, Cultured	1994
Synthesis and evaluation of new 6-amino-substituted benzo[c]phenanthridine derivatives. Journal of medicinal chemistry, 1993, Nov-12, Volume: 36, Issue:23 Topics: Adenocarcinoma; Alkaloids; Animals; Antineoplastic Agents; Benzophenanthridines; Breast Neoplasms; Humans; Leukemia L1210; Leukemia P388; Mice; Molecular Structure; Phenanthridines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured	1993
DNA topoisomerase I inhibitors: cytotoxic flavones from Lethedon tannaensis. Journal of natural products, 1996, Volume: 59, Issue:7 Topics: Animals; Antineoplastic Agents, Phytogenic; Flavonoids; Humans; KB Cells; Leukemia P388; Magnetic Resonance Spectroscopy; Mice; New Caledonia; Plants, Medicinal; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Topoisomerase I Inhibitors	1996
Synthesis and antitumor activity of ring A- and F-modified hexacyclic camptothecin analogues. Journal of medicinal chemistry, 1998, Jun-18, Volume: 41, Issue:13 Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Division; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Irinotecan; Leukemia P388; Mice; Structure-Activity Relationship; Topoisomerase I Inhibitors; Tumor Cells, Cultured	1998
Synthesis and cytotoxic activity of 7-oxo-7H-dibenz[f,ij]isoquinoline and 7-oxo-7H-benzo[e]perimidine derivatives. Journal of medicinal chemistry, 2001, Jun-07, Volume: 44, Issue:12 Topics: Animals; Antineoplastic Agents; Cell Survival; Colonic Neoplasms; Doxorubicin; Drug Design; Drug Resistance, Neoplasm; Humans; Indicators and Reagents; Isoquinolines; Jurkat Cells; Leukemia P388; Lung Neoplasms; Mice; Mice, Inbred Strains; Models, Molecular; Molecular Conformation; Molecular Structure; Quinazolines; Structure-Activity Relationship; Tumor Cells, Cultured	2001
Selective phenolic acylation of 10-hydroxycamptothecin using poly (ethylene glycol) carboxylic acid. Bioorganic & medicinal chemistry letters, 2003, Feb-10, Volume: 13, Issue:3 Topics: Acylation; Animals; Antineoplastic Agents; Camptothecin; Carboxylic Acids; Hydrogen Bonding; Hydroxyquinolines; Indicators and Reagents; Leukemia P388; Magnetic Resonance Spectroscopy; Neoplasms; Polyethylene Glycols; Rats; Tumor Cells, Cultured	2003
Alvaradoins E-N, antitumor and cytotoxic anthracenone C-glycosides from the leaves of Alvaradoa haitiensis. Journal of natural products, 2007, Volume: 70, Issue:6 Topics: Animals; Anthracenes; Antineoplastic Agents, Phytogenic; Dominican Republic; Drug Screening Assays, Antitumor; Humans; KB Cells; Leukemia P388; Models, Biological; Molecular Structure; Monosaccharides; Plant Leaves; Plants, Medicinal; Simaroubaceae; Structure-Activity Relationship	2007
Synthesis of ferulic ester dimers, functionalisation and biological evaluation as potential antiatherogenic and antiplasmodial agents. Bioorganic & medicinal chemistry, 2007, Sep-15, Volume: 15, Issue:18 Topics: Animals; Antioxidants; Atherosclerosis; Cell Survival; Coumaric Acids; Dimerization; Endothelium, Vascular; Esters; Humans; Leukemia P388; Lipoproteins, LDL; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Thiobarbituric Acid Reactive Substances	2007
Attenuation of cytogenetic effects by erythropoietin in human lymphocytes in vitro and P388 ascites tumor cells in vivo treated with irinotecan (CPT-11). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:1 Topics: Adolescent; Adult; Animals; Antimutagenic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Proliferation; Cells, Cultured; Erythropoietin; Humans; In Vitro Techniques; Irinotecan; Leukemia P388; Lymphocytes; Mice; Mitosis; Mutagens; Recombinant Proteins; Sister Chromatid Exchange; Young Adult	2010
Altered serine/arginine-rich protein phosphorylation and exonic enhancer-dependent splicing in Mammalian cells lacking topoisomerase I. Cancer research, 2003, Dec-01, Volume: 63, Issue:23 Topics: Alternative Splicing; Animals; Antineoplastic Agents; Camptothecin; DNA Topoisomerases, Type I; Down-Regulation; Drug Resistance, Neoplasm; Exons; Gene Expression Regulation, Leukemic; Green Fluorescent Proteins; Leukemia P388; Luminescent Proteins; Mice; Nuclear Proteins; Phosphoproteins; Phosphorylation; Recombinant Fusion Proteins; RNA Splicing; RNA-Binding Proteins; Serine-Arginine Splicing Factors; Transcriptional Activation	2003
A novel polypyrimidine antitumor agent FdUMP[10] induces thymineless death with topoisomerase I-DNA complexes. Cancer research, 2005, Jun-01, Volume: 65, Issue:11 Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Death; DNA Damage; DNA Topoisomerases, Type I; DNA, Neoplasm; DNA, Single-Stranded; Drug Screening Assays, Antitumor; Fluorodeoxyuridylate; Fluorouracil; Leukemia P388; Mice; Quinazolines; Thiophenes; Thymidine; Thymidylate Synthase; Topoisomerase I Inhibitors	2005
Cancer cell mitochondria are direct proapoptotic targets for the marine antitumor drug lamellarin D. Cancer research, 2006, Mar-15, Volume: 66, Issue:6 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Camptothecin; Cell Line, Tumor; Cell Membrane Permeability; Cell-Free System; Coumarins; Cytochromes c; Heterocyclic Compounds, 4 or More Rings; Humans; Isoquinolines; Leukemia P388; Lung Neoplasms; Membrane Potentials; Mice; Mitochondria; Mitochondrial Membranes; NIH 3T3 Cells; Rats	2006
Action of (S)-10-hydroxycamptothecin on P388 leukemia and distribution of the drug in mice. Cancer treatment reports, 1983, Volume: 67, Issue:2 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; DNA, Neoplasm; Flow Cytometry; Leukemia P388; Leukemia, Experimental; Mice; Tissue Distribution	1983
In vitro and in vivo effects of clinically important camptothecin analogues on multidrug-resistant cells. Oncology research, 1993, Volume: 5, Issue:12 Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Survival; CHO Cells; Cricetinae; DNA Damage; Drug Resistance; Female; Irinotecan; Leukemia P388; Mice; Topotecan	1993
The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerases I and II. Biochemical pharmacology, 1993, Oct-19, Volume: 46, Issue:8 Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Benzophenanthridines; Camptothecin; Catalysis; Cattle; Cricetinae; Cricetulus; DNA; DNA Topoisomerases, Type II; Drug Resistance; Fibrosarcoma; Intercalating Agents; Leukemia P388; Mice; Phenanthridines; Topoisomerase II Inhibitors; Tumor Cells, Cultured	1993
Lipid-complexed camptothecin: formulation and initial biodistribution and antitumor activity studies. Cancer chemotherapy and pharmacology, 1996, Volume: 37, Issue:6 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Survival; Humans; Leukemia L1210; Leukemia P388; Lipids; Metabolic Clearance Rate; Mice; Tissue Distribution; Tumor Cells, Cultured	1996
Camptothecin-20-PEG ester transport forms: the effect of spacer groups on antitumor activity. Bioorganic & medicinal chemistry, 1998, Volume: 6, Issue:5 Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Biological Transport; Camptothecin; Colorectal Neoplasms; Humans; Leukemia P388; Magnetic Resonance Spectroscopy; Mice; Neoplasm Transplantation; Rats; Spectrometry, Mass, Fast Atom Bombardment; Tumor Cells, Cultured	1998
Identification of a new metabolite of CPT-11 (irinotecan): pharmacological properties and activation to SN-38. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:1 Topics: Animals; Antineoplastic Agents, Phytogenic; Biotransformation; Camptothecin; Humans; Irinotecan; Leukemia P388; Microsomes, Liver; Tumor Cells, Cultured	1998
A new mechanism of acquisition of drug resistance by partial duplication of topoisomerase I. Cancer research, 1999, Jun-01, Volume: 59, Issue:11 Topics: Animals; Antineoplastic Agents; Camptothecin; Carbazoles; DNA Damage; DNA Topoisomerases, Type I; DNA, Complementary; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gene Rearrangement; Glucosides; Humans; Leukemia P388; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; Topoisomerase I Inhibitors	1999
Homocamptothecin, an E-ring-modified camptothecin analogue, generates new topoisomerase I-mediated DNA breaks. Biochemistry, 1999, Nov-23, Volume: 38, Issue:47 Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Survival; DNA Topoisomerases, Type I; DNA, Superhelical; Drug Resistance, Neoplasm; Enzyme Inhibitors; Leukemia P388; Mice; Structure-Activity Relationship; Topoisomerase I Inhibitors; Tumor Cells, Cultured	1999
Relation between intracellular acidification and camptothecin-induced apoptosis in leukemia cells. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2000, Volume: 10, Issue:2 Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Calcium; Camptothecin; Cell Cycle; Cell Survival; DNA Fragmentation; Electrophoresis, Agar Gel; Enzyme Inhibitors; HL-60 Cells; Humans; Hydrogen-Ion Concentration; Leukemia P388; Topoisomerase II Inhibitors	2000
Enhanced cytogenetic and antitumor effects by 9-nitrocamptothecin and antineoplastics. Teratogenesis, carcinogenesis, and mutagenesis, 2000, Volume: 20, Issue:3 Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Division; Drug Screening Assays, Antitumor; Epirubicin; Humans; Leukemia P388; Lymphocytes; Melphalan; Mice; Sister Chromatid Exchange	2000
Camptothecin delivery systems: the utility of amino acid spacers for the conjugation of camptothecin with polyethylene glycol to create prodrugs. Anti-cancer drug design, 1999, Volume: 14, Issue:6 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Drug Delivery Systems; Drug Design; Drug Screening Assays, Antitumor; Female; Humans; Hydrolysis; Leukemia P388; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Polyethylene Glycols; Prodrugs; Rats; Solvents; Tumor Cells, Cultured	1999
Activity of a novel camptothecin analogue, homocamptothecin, in camptothecin-resistant cell lines with topoisomerase I alterations. Cancer research, 2000, Dec-01, Volume: 60, Issue:23 Topics: Animals; Antineoplastic Agents; Camptothecin; Cricetinae; DNA Topoisomerases, Type I; DNA, Neoplasm; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Enzyme Stability; Humans; Inhibitory Concentration 50; Leukemia P388; Male; Mice; Point Mutation; Prostatic Neoplasms; Topoisomerase I Inhibitors; Tumor Cells, Cultured	2000
Antitumor agents. V. Synthesis and antileukemic activity of E-ring-modified (RS)-camptothecin analogues. Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:3 Topics: Animals; Antineoplastic Agents; Camptothecin; Drug Screening Assays, Antitumor; Leukemia P388; Magnetic Resonance Spectroscopy; Mice; Tumor Cells, Cultured	1992
Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11. Cancer research, 1991, Aug-15, Volume: 51, Issue:16 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Survival; DNA Damage; DNA Replication; DNA, Single-Stranded; Irinotecan; Kinetics; Leukemia P388; Mice; RNA, Neoplasm; Thymidine; Topoisomerase I Inhibitors; Uridine	1991
Synergistic cell killing by ionizing radiation and topoisomerase I inhibitor topotecan (SK&F 104864). Cancer research, 1991, Nov-01, Volume: 51, Issue:21 Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Survival; CHO Cells; Cricetinae; Dose-Response Relationship, Radiation; Drug Screening Assays, Antitumor; Gamma Rays; Leukemia P388; Mice; Topoisomerase I Inhibitors; Topotecan; Tumor Cells, Cultured	1991
Development of a stable camptothecin-resistant subline of P388 leukemia with reduced topoisomerase I content. Molecular pharmacology, 1990, Volume: 38, Issue:4 Topics: Animals; Camptothecin; DNA; DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Resistance; Gene Rearrangement; Leukemia P388; Mice; Mice, Inbred DBA; RNA, Messenger; Tumor Cells, Cultured	1990
Nonproductive rearrangement of DNA topoisomerase I and II genes: correlation with resistance to topoisomerase inhibitors. Journal of the National Cancer Institute, 1989, Nov-15, Volume: 81, Issue:22 Topics: Alleles; Amsacrine; Animals; Camptothecin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Resistance; Gene Expression Regulation; Gene Rearrangement; Leukemia P388; Leukemia, Experimental; Methylation; Methyltransferases; Mice; RNA, Messenger; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transcription, Genetic	1989
Synthesis and antileukemic activity of (+-)-20-deoxyaminocamptothecin analogues. Chemical & pharmaceutical bulletin, 1989, Volume: 37, Issue:8 Topics: Animals; Antineoplastic Agents; Camptothecin; Leukemia P388; Mice	1989
Antitumor effect of CPT-11, a new derivative of camptothecin, against pleiotropic drug-resistant tumors in vitro and in vivo. Cancer chemotherapy and pharmacology, 1988, Volume: 21, Issue:1 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Doxorubicin; Drug Resistance; Irinotecan; Leukemia P388; Neoplasms, Experimental; Tumor Cells, Cultured; Vincristine	1988