Page last updated: 2024-08-22

camptothecin and Leukemia L 1210

camptothecin has been researched along with Leukemia L 1210 in 53 studies

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	25 (47.17)	18.7374
1990's	23 (43.40)	18.2507
2000's	4 (7.55)	29.6817
2010's	1 (1.89)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Adamovics, JA; Hutchinson, CR	1
Boehm, JC; Caranfa, MJ; Faucette, LF; Gallagher, G; Hecht, SM; Holden, KG; Jakas, DR; Johnson, RK; Kingsbury, WD; McCabe, FL	1
Kohn, KW; Manikumar, G; Nicholas, AW; Pommier, Y; Wall, ME; Wani, MC	1
Bartus, JO; Caranfa, MJ; Gallagher, G; Hertzberg, RP; Holden, KG; Jakas, DR; Johnson, RK; Kingsbury, WD; Mattern, MR; Mong, SM	1
Natschke, SM; Nicholas, AW; Wall, ME; Wani, MC	1
Nicholas, AW; Wall, ME; Wani, MC	1
Bisagni, E; Croisy, A; Janin, YL; Riou, JF	1
Besterman, JM; Leitner, P; Manikumar, G; Moore, L; Nicholas, AW; Tele, C; Truesdale, A; Wall, ME; Wani, MC	1
Alajarín, R; Alvarez-Builla, J; Benito, EJ; Caignard, D; Fontana, A; Lambel-Giraudet, S; Leonce, S; Martín, MJ; Pierré, A; Sánchez, N; Vaquero, JJ	1
Lang, M; Wang, Y; Xia, L; Yu, P; Zhang, G; Zhang, Z; Zhao, J	1
Broggini, M; Colombo, T; Geroni, C; Marchini, S; Sabatino, MA	1
Jiang, W; Larrick, JW; Li, L; Wang, Y	1
Furuta, T; Miyasaka, T; Nagata, H; Sawada, S; Yaegashi, T; Yokokura, T	1
Furue, H	1
Furuta, T; Miyasaka, T; Sawada, S; Yaegashi, T; Yamaguchi, K; Yokokura, T	1
Furuta, T; Miyasaka, T; Sawada, S; Yaegashi, T; Yokokura, T	1
Kumi, R; Perez-Soler, R; Poirot, K; Reddy, S; Sugarman, SM; Wasan, K; Zou, Y	1
Ganapathi, R; Grabowski, D	1
Aalders, M; El-Gawly, H; Gabr, A; Kuin, A; Smets, LA	1
Duraj, J; Novotný, L; Rauko, P; Sedlák, J; Szekeres, MF	1
Bailly, C; Bigg, DC; Camara, J; Dassonneville, L; Demarquay, D; Kasprzyk, PG; Kiss, R; Lavergne, O; Lesueur-Ginot, L	1
Bowman, KJ; Calvert, AH; Curtin, NJ; Newell, DR	1
Adamson, RH; Mead, JA; Sieber, SM	1
Taylor, H; Wall, ME; Wani, MC	1
Bristol, JA; Comins, DL; Davenport, RW; Horwitz, SB; Kane, MJ; Lyle, RE; Maloney, JR; Portlock, DE	1
Sugasawa, T; Toyoda, T; Uchida, N; Yamaguchi, K	1
Furuta, T; Miyasaka, T; Nokata, K; Sawada, S; Yaegashi, T; Yokokura, T	1
Capranico, G; Jaxel, C; Kerrigan, D; Kohn, KW; Pommier, Y	1
Beerman, TA; McHugh, MM; Sigmund, RD	1
Furuta, T; Miyasaka, T; Nokata, K; Sawada, S; Yokokura, T	1
Furuta, T; Matsuoka, S; Miyasaka, T; Nagata, H; Nokata, K; Sawada, S; Yokokura, T	1
Furuta, T; Yokokura, T	2
Aiyama, R; Furuta, T; Miyasaka, T; Nokata, K; Okajima, S; Sawada, S; Sugino, E; Yamaguchi, K; Yokokura, T	1
Darzynkiewicz, Z; Del Bino, G; Skierski, JS	1
Furuta, T; Kaneda, N; Nagata, H; Yokokura, T	1
Hsiang, YH; Kirschenbaum, S; Liu, LF; Manikumar, G; Nicholas, AW; Potmesil, M; Silber, R; Wall, ME; Wani, MC	1
Hsiang, YH; Lihou, MG; Liu, LF	1
Hsiang, YH; Liu, LF	1
Bartus, HF; Crooke, ST; Johnson, RK; Mattern, MR; Mirabelli, CK; Mong, SM	1
Baba, H; Kunimoto, T; Miyasaka, T; Mutai, M; Nitta, K; Sawada, S; Takeuchi, M; Tanaka, T; Uehara, N; Yokokura, T	2
Manikumar, G; Nicholas, AW; Wall, ME; Wani, MC	1
Fukada, M; Furuta, T; Kaneda, N; Miyasaka, T; Nagata, H; Notake, K; Sawada, S; Yokokura, T	1
Kann, HE; Kohn, KW	1
Gang, M; Kline, I; Sirica, AE; Venditti, JM; Woodman, RJ	1
Kline, I	1
Brockman, RW	1
Horwitz, SB	1
Bhuyan, BK; Fraser, TJ; Li, LH; Olin, EJ	1
Homan, ER; Neil, GL	1
Bhuyan, BK; Fraser, TJ; Gray, LG; Kuentzel, SL; Neil, GL	1
Dysard, R; Kessel, D	1

Reviews

4 review(s) available for camptothecin and Leukemia L 1210

Article	Year
[Irinotecan hydrochloride (CPT-11)]. Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:5 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Female; Humans; Irinotecan; Leukemia L1210; Lung Neoplasms; Ovarian Neoplasms; Uterine Cervical Neoplasms	1994
Pharmacology of antitumor agents from higher plants. Cancer treatment reports, 1976, Volume: 60, Issue:8 Topics: Animals; Antineoplastic Agents, Phytogenic; Aporphines; Camptothecin; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Etoposide; Humans; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Maytansine; Melanoma; Naphthoquinones; Nasopharyngeal Neoplasms; Neoplasms; Neoplasms, Experimental; Phenanthrenes; Structure-Activity Relationship; Teniposide; Vinblastine; Vincristine	1976
Biochemical aspects of drug combinations. Cancer chemotherapy reports. Part 2, 1974, Volume: 4, Issue:1 Topics: Alkylating Agents; Animals; Antineoplastic Agents; Bleomycin; Camptothecin; Cell Division; Cytarabine; Deferoxamine; Diamines; DNA, Neoplasm; Doxorubicin; Drug Therapy, Combination; Leukemia L1210; Macromolecular Substances; Mice; Neoplasms; Neoplasms, Experimental; Nitrosourea Compounds; Purine Nucleotides; Ribonucleotide Reductases; Thioguanine; Triazoles	1974
Novel inhibitors of RNA synthesis. Federation proceedings, 1974, Volume: 33, Issue:11 Topics: Acrylamides; Animals; Antibiotics, Antineoplastic; Benzoates; Benzodiazepinones; Bleomycin; Camptothecin; Centrifugation, Density Gradient; Cycloparaffins; Depression, Chemical; DNA; DNA Replication; DNA-Directed RNA Polymerases; Escherichia coli; HeLa Cells; Lactones; Leukemia L1210; Mitosis; Nucleic Acid Denaturation; Pyrroles; RNA; RNA, Ribosomal; RNA, Viral; Structure-Activity Relationship; Templates, Genetic; Uracil Nucleotides; Uridine; Vaccinia virus; Virus Replication; Xanthenes	1974

Other Studies

49 other study(ies) available for camptothecin and Leukemia L 1210

Article	Year
Prodrug analogues of the antitumor alkaloid camptothecin. Journal of medicinal chemistry, 1979, Volume: 22, Issue:3 Topics: Animals; Antineoplastic Agents; Camptothecin; Leukemia L1210; Leukemia, Experimental; Lung Neoplasms; Melanoma; Mice; Neoplasms, Experimental	1979
Synthesis of water-soluble (aminoalkyl)camptothecin analogues: inhibition of topoisomerase I and antitumor activity. Journal of medicinal chemistry, 1991, Volume: 34, Issue:1 Topics: Animals; Antineoplastic Agents; Camptothecin; Cattle; Cell Line; Colonic Neoplasms; DNA, Superhelical; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Leukemia L1210; Lung Neoplasms; Melanoma, Experimental; Mice; Molecular Structure; Plasmids; Structure-Activity Relationship; Thymus Gland; Topoisomerase I Inhibitors; Transplantation, Heterologous	1991
Plant antitumor agents. 29. Synthesis and biological activity of ring D and ring E modified analogues of camptothecin. Journal of medicinal chemistry, 1990, Volume: 33, Issue:3 Topics: Animals; Camptothecin; Leukemia L1210; Mice; Structure-Activity Relationship; Topoisomerase I Inhibitors	1990
Modification of the hydroxy lactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity. Journal of medicinal chemistry, 1989, Volume: 32, Issue:3 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chemical Phenomena; Chemistry; Drug Screening Assays, Antitumor; Leukemia L1210; Mice; Structure-Activity Relationship; Topoisomerase I Inhibitors	1989
Plant antitumor agents. 22. Isolation of 11-hydroxycamptothecin from Camptotheca acuminata Decne: total synthesis and biological activity. Journal of medicinal chemistry, 1986, Volume: 29, Issue:8 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Isomerism; Leukemia L1210; Mice; Structure-Activity Relationship	1986
Plant antitumor agents. 23. Synthesis and antileukemic activity of camptothecin analogues. Journal of medicinal chemistry, 1986, Volume: 29, Issue:11 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Leukemia L1210; Solubility; Structure-Activity Relationship	1986
Synthesis and evaluation of new 6-amino-substituted benzo[c]phenanthridine derivatives. Journal of medicinal chemistry, 1993, Nov-12, Volume: 36, Issue:23 Topics: Adenocarcinoma; Alkaloids; Animals; Antineoplastic Agents; Benzophenanthridines; Breast Neoplasms; Humans; Leukemia L1210; Leukemia P388; Mice; Molecular Structure; Phenanthridines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured	1993
Plant antitumor agents. 30. Synthesis and structure activity of novel camptothecin analogs. Journal of medicinal chemistry, 1993, Sep-03, Volume: 36, Issue:18 Topics: Animals; Antineoplastic Agents; Camptothecin; Female; Humans; Leukemia L1210; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred DBA; Molecular Conformation; Molecular Structure; Plants, Medicinal; Stereoisomerism; Structure-Activity Relationship; Topoisomerase I Inhibitors; Tumor Cells, Cultured	1993
Synthesis and cytotoxic activity of pyridazino[1',6':1,2]pyrido[3,4-b]indol-5-inium derivatives as anti-cancer agents. Bioorganic & medicinal chemistry letters, 2002, Sep-16, Volume: 12, Issue:18 Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Indoles; Leukemia L1210; Tumor Cells, Cultured	2002
Synthesis and preliminary anticancer evaluation of 10-hydroxycamptothecin analogs. Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:8 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptotheca; Camptothecin; Cell Line, Tumor; Leukemia L1210; Phytotherapy; Plant Extracts; Treatment Outcome	2012
Enhancement of in vivo antitumor activity of classical anticancer agents by combination with the new, glutathione-interacting DNA minor groove-binder, brostallicin. Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Nov-01, Volume: 9, Issue:14 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Colonic Neoplasms; DNA; Doxorubicin; Female; Glutathione; Glutathione Transferase; Guanidines; Irinotecan; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred DBA; Mice, Nude; Pyrroles; Transplantation, Heterologous	2003
Synthesis and evaluation of a DHA and 10-hydroxycamptothecin conjugate. Bioorganic & medicinal chemistry, 2005, Oct-01, Volume: 13, Issue:19 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Lewis Lung; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Disease Models, Animal; Docosahexaenoic Acids; Drug Design; Drug Screening Assays, Antitumor; Humans; Leukemia L1210; Mice; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship	2005
Synthesis and antitumor activity of 20(S)-camptothecin derivatives. A-ring-substituted 7-ethylcamptothecins and their E-ring-modified water-soluble derivatives. Chemical & pharmaceutical bulletin, 1994, Volume: 42, Issue:12 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chemical Phenomena; Chemistry, Physical; Drug Screening Assays, Antitumor; Female; Humans; KB Cells; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Plants, Medicinal; Topoisomerase I Inhibitors	1994
Chemical modification of antitumor alkaloids, 20(S)-camptothecin and 7-ethylcamptothecin: reaction of the E-lactone ring portion with hydrazine hydrate. Chemical & pharmaceutical bulletin, 1993, Volume: 41, Issue:5 Topics: Animals; Camptothecin; Female; Hydrazines; Leukemia L1210; Mice	1993
Chemical modification of an antitumor alkaloid, 20(S)-camptothecin: E-lactone ring-modified water-soluble derivatives of 7-ethylcamptothecin. Chemical & pharmaceutical bulletin, 1993, Volume: 41, Issue:2 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Lactones; Leukemia L1210; Mice; Solubility; Water	1993
Lipid-complexed camptothecin: formulation and initial biodistribution and antitumor activity studies. Cancer chemotherapy and pharmacology, 1996, Volume: 37, Issue:6 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Survival; Humans; Leukemia L1210; Leukemia P388; Lipids; Metabolic Clearance Rate; Mice; Tissue Distribution; Tumor Cells, Cultured	1996
Cytotoxic efficacy with combinations of topoisomerase I and topoisomerase II inhibitors in sensitive and multidrug-resistant L1210 mouse leukemia cells. Annals of the New York Academy of Sciences, 1996, Dec-13, Volume: 803 Topics: Amsacrine; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Resistance, Multiple; Drug Synergism; Enzyme Inhibitors; Etoposide; Leukemia L1210; Mice; Mitoxantrone; Topoisomerase I Inhibitors; Topotecan	1996
Cellular pharmacokinetics and cytotoxicity of camptothecin and topotecan at normal and acidic pH. Cancer research, 1997, Nov-01, Volume: 57, Issue:21 Topics: Animals; Antineoplastic Agents; Camptothecin; DNA, Neoplasm; Hydrogen-Ion Concentration; Leukemia L1210; Mice; Mice, Inbred C3H; Topotecan	1997
Pentoxifylline stimulates drug-induced apoptosis in leukemic cells. Neoplasma, 1998, Volume: 45, Issue:5 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Cell Cycle; Cell Division; Cisplatin; DNA Damage; DNA, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; G2 Phase; Leukemia L1210; Mice; Pentoxifylline; Stimulation, Chemical	1998
Homocamptothecin, an E-ring modified camptothecin with enhanced lactone stability, retains topoisomerase I-targeted activity and antitumor properties. Cancer research, 1999, Jun-15, Volume: 59, Issue:12 Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Division; Disease Models, Animal; DNA; Drug Screening Assays, Antitumor; Drug Stability; Enzyme Inhibitors; HT29 Cells; Humans; K562 Cells; Lactones; Leukemia L1210; Leukemia, Experimental; Neoplasm Transplantation; Topoisomerase I Inhibitors; Transplantation, Heterologous; Tumor Cells, Cultured	1999
Differential effects of the poly (ADP-ribose) polymerase (PARP) inhibitor NU1025 on topoisomerase I and II inhibitor cytotoxicity in L1210 cells in vitro. British journal of cancer, 2001, Jan-05, Volume: 84, Issue:1 Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; DNA Damage; DNA, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Etoposide; Leukemia L1210; Nucleic Acid Synthesis Inhibitors; Proteins; Quinazolines; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors	2001
Isolation and chemical characterization of antitumor agents from plants. Cancer treatment reports, 1976, Volume: 60, Issue:8 Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carubicin; Chemical Fractionation; Chemical Phenomena; Chemistry; Chromatography; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Countercurrent Distribution; Humans; Leukemia L1210; Leukemia, Experimental; Longevity; Mice; Neoplasms; Plant Extracts; Spectrum Analysis	1976
Analogs of camptothecin. Journal of medicinal chemistry, 1975, Volume: 18, Issue:5 Topics: Animals; Camptothecin; Carcinoma; Cell Line; Leukemia L1210; Mouth Neoplasms	1975
Experiments of synthesis of dl-camptothecin. 4. Synthesis and antileukemic activity of dl-camptothecin analogues. Journal of medicinal chemistry, 1976, Volume: 19, Issue:5 Topics: Animals; Camptothecin; Female; Leukemia L1210; Mice; Mice, Inbred Strains; Stereoisomerism; Structure-Activity Relationship	1976
Chemical modification of an antitumor alkaloid, 20(S)-camptothecin: glycosides, phosphates and sulfates of 7-ethyl-10-hydroxycamptothecin. Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:1 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Female; Glycosides; Irinotecan; Leukemia L1210; Mice; Mice, Inbred Strains; Phosphates; Sulfates	1992
Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin. The Journal of biological chemistry, 1991, Oct-25, Volume: 266, Issue:30 Topics: Animals; Base Sequence; Camptothecin; DNA Topoisomerases, Type I; DNA, Neoplasm; Hydrolysis; Leukemia L1210; Mice; Molecular Sequence Data; Substrate Specificity	1991
Effects of minor groove binding drugs on camptothecin-induced DNA lesions in L1210 nuclei. Biochemical pharmacology, 1990, Feb-15, Volume: 39, Issue:4 Topics: Animals; Benzimidazoles; Bisbenzimidazole; Camptothecin; Cell Nucleus; Distamycins; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Interactions; Indoles; Leukemia L1210; Molecular Structure; Pyrroles; Topoisomerase I Inhibitors	1990
Chemical modification of an antitumor alkaloid camptothecin: synthesis and antitumor activity of 7-C-substituted camptothecins. Chemical & pharmaceutical bulletin, 1991, Volume: 39, Issue:10 Topics: Animals; Antineoplastic Agents; Camptothecin; Female; Leukemia L1210; Mice; Structure-Activity Relationship	1991
Synthesis and antitumor activity of 20(S)-camptothecin derivatives: A-ring modified and 7,10-disubstituted camptothecins. Chemical & pharmaceutical bulletin, 1991, Volume: 39, Issue:12 Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Survival; Female; Humans; KB Cells; Leukemia L1210; Mice; Mice, Inbred Strains	1991
[Combination therapy of CPT-11, a camptothecin derivative, with various antitumor drugs against L 1210 leukemia]. Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:3 Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Cyclophosphamide; Female; Irinotecan; Leukemia L1210; Methotrexate; Mice; Mitomycin; Mitomycins; Thioinosine	1991
Synthesis and antitumor activity of 20(S)-camptothecin derivatives: carbamate-linked, water-soluble derivatives of 7-ethyl-10-hydroxycamptothecin. Chemical & pharmaceutical bulletin, 1991, Volume: 39, Issue:6 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carbamates; Female; Irinotecan; Leukemia L1210; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Solubility; Water	1991
Diverse effects of camptothecin, an inhibitor of topoisomerase I, on the cell cycle of lymphocytic (L1210, MOLT-4) and myelogenous (HL-60, KG1) leukemic cells. Cancer research, 1990, Sep-15, Volume: 50, Issue:18 Topics: Animals; Camptothecin; DNA, Neoplasm; Humans; Interphase; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid; Mice; Topoisomerase I Inhibitors; Tumor Cells, Cultured	1990
[Effect of administration schedules on the antitumor activity of CPT-11, a camptothecin derivative]. Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:1 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Female; Fibrosarcoma; Injections, Intraperitoneal; Injections, Intravenous; Irinotecan; Leukemia L1210; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental	1990
Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse. Cancer research, 1990, Mar-15, Volume: 50, Issue:6 Topics: Animals; Antineoplastic Agents, Phytogenic; Biotransformation; Camptothecin; Cell Division; Irinotecan; Kinetics; Leukemia L1210; Mice; Mice, Inbred Strains; Tissue Distribution; Tumor Cells, Cultured	1990
DNA topoisomerase I-mediated DNA cleavage and cytotoxicity of camptothecin analogues. Cancer research, 1989, Aug-15, Volume: 49, Issue:16 Topics: Animals; Camptothecin; Cell Survival; DNA Damage; DNA Topoisomerases, Type I; DNA, Circular; DNA, Neoplasm; Dose-Response Relationship, Drug; Leukemia L1210; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Structure-Activity Relationship	1989
Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin. Cancer research, 1989, Sep-15, Volume: 49, Issue:18 Topics: Animals; Aphidicolin; Camptothecin; Cattle; Cell Survival; Diterpenes; DNA Damage; DNA Replication; DNA, Viral; Kinetics; Leukemia L1210; Mice; Simian virus 40; Thymus Gland; Topoisomerase I Inhibitors; Tumor Stem Cell Assay	1989
Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin. Cancer research, 1988, Apr-01, Volume: 48, Issue:7 Topics: Animals; Camptothecin; Cell Line; Cross-Linking Reagents; DNA Damage; DNA, Viral; Leukemia L1210; Mice; Simian virus 40; Topoisomerase I Inhibitors	1988
Relationship between the intracellular effects of camptothecin and the inhibition of DNA topoisomerase I in cultured L1210 cells. Cancer research, 1987, Apr-01, Volume: 47, Issue:7 Topics: Animals; Camptothecin; DNA Damage; DNA, Neoplasm; Leukemia L1210; Mice; Neoplasm Proteins; Topoisomerase I Inhibitors	1987
[Antitumor activity of new derivatives of camptothecin]. Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:3 Pt 2 Topics: Animals; Antineoplastic Agents; Camptothecin; Doxorubicin; Irinotecan; Lethal Dose 50; Leukemia L1210; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred ICR; Neoplasms, Experimental	1987
Antitumor activity of a new camptothecin derivative, SN-22, against various murine tumors. Journal of pharmacobio-dynamics, 1987, Volume: 10, Issue:3 Topics: Animals; Antineoplastic Agents; Camptothecin; Lethal Dose 50; Leukemia L1210; Mice; Mice, Inbred Strains; Neoplasms, Experimental	1987
Plant antitumor agents. 25. Total synthesis and antileukemic activity of ring A substituted camptothecin analogues. Structure-activity correlations. Journal of medicinal chemistry, 1987, Volume: 30, Issue:10 Topics: Animals; Camptothecin; Cell Line; Leukemia L1210; Plant Extracts; Structure-Activity Relationship	1987
Action of 7-ethylcamptothecin on tumor cells and its disposition in mice. Cancer treatment reports, 1987, Volume: 71, Issue:4 Topics: Animals; Camptothecin; Cell Cycle; Cell Division; Chromatography, High Pressure Liquid; Female; Flow Cytometry; Kinetics; Leukemia L1210; Mice; Tissue Distribution	1987
Effects of deoxyribonucleic acid-reactive drugs on ribonucleic acid synthesis in leukemia L1210 cells. Molecular pharmacology, 1972, Volume: 8, Issue:5 Topics: Acridines; Acrylamides; Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Benzazepines; Camptothecin; Carbazoles; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Centrifugation, Density Gradient; Dactinomycin; Daunorubicin; Deoxyadenosines; DNA, Neoplasm; Ethidium; Leukemia L1210; Mechlorethamine; Methionine; Phenanthridines; Pyridines; Pyrroles; RNA, Neoplasm; Tritium; Uridine	1972
The enhanced therapeutic effect of cis-platinum (II) diamminodichloride against L1210 leukemia when combined with cyclophosphamide or 1,2-bis(3,5-dioxopiperazine-1-yl)propane or several other antitumor agents. Chemotherapy, 1973, Volume: 18, Issue:3 Topics: Amines; Animals; Antineoplastic Agents; Azacitidine; Camptothecin; Carmustine; Chlorides; Cyclophosphamide; Cytarabine; Drug Synergism; Emetine; Fluorouracil; Ketones; Leukemia L1210; Male; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Piperazines; Platinum; Propane; Time Factors	1973
Potentially useful combinations of chemotherapy detected in mouse tumor systems. Cancer chemotherapy reports. Part 2, 1974, Volume: 4, Issue:1 Topics: Acetylcysteine; Animals; Antineoplastic Agents; Azauridine; Bleomycin; Camptothecin; Cyclic P-Oxides; Cyclophosphamide; Cytarabine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ethylamines; Fluorouracil; Imidazoles; Leukemia L1210; Lung Neoplasms; Methotrexate; Mice; Neoplasms, Experimental; Oxazines; Piperazines; Procarbazine; Propane; Triazenes	1974
Action of camptothecin on mammalian cells in culture. Cancer research, 1972, Volume: 32, Issue:12 Topics: Animals; Camptothecin; Cell Line; Cell Survival; Cricetinae; Deoxyuridine; DNA Nucleotidyltransferases; DNA Replication; DNA, Neoplasm; Leukemia L1210; Lung; Mitosis; Neoplasms, Experimental; Phosphotransferases; RNA, Neoplasm; Thymidine Kinase; Time Factors; Tritium	1972
The effect of dose interval on the survival of L1210 leukemic mice treated with DNA synthesis inhibitors. Cancer research, 1973, Volume: 33, Issue:4 Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Division; Cell Survival; Cytarabine; DNA, Neoplasm; Formates; Hydroxyurea; Leukemia L1210; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pyridines; Thiosemicarbazones; Thymidine; Time Factors	1973
Cell-kill kinetics of several S-phase-specific drugs. Cancer research, 1973, Volume: 33, Issue:4 Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Division; Cell Line; Cell Survival; Cricetinae; Cytarabine; DNA, Neoplasm; Formates; Hydroxyurea; Kinetics; Leukemia L1210; Lung; Mice; Neoplasms, Experimental; Pyridines; Thiosemicarbazones; Time Factors	1973
Effects of camptothecin on RNA synthesis in L-1210 cells. Biochimica et biophysica acta, 1973, Jul-27, Volume: 312, Issue:4 Topics: Animals; Camptothecin; Carbon Isotopes; Centrifugation, Density Gradient; Clone Cells; Leukemia L1210; Methylation; Mice; Nucleotides; Phosphorus Isotopes; RNA; RNA, Ribosomal; Time Factors; Uridine	1973