camptothecin has been researched along with Leukemia, Promyelocytic, Acute in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.23) | 18.7374 |
| 1990's | 24 (77.42) | 18.2507 |
| 2000's | 3 (9.68) | 29.6817 |
| 2010's | 3 (9.68) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, YL; Chiang, JH; Chueh, FS; Chung, JG; Hsueh, SC; Lee, CS; Lu, CC; Lu, HF; Yang, JS | 1 |
| Bernardi, R; Coltella, N; Ponente, M; Ponzoni, M; Valsecchi, R | 1 |
| Ahn, JH; Boo, JH; Jeon, GS; Kang, DE; Kim, C; Kim, KH; Kim, YE; Mook-Jung, I; Ryu, H; Song, H | 1 |
| Cahn, JY; Merrouche, Y; Mugneret, F | 1 |
| Chen, GQ; Guo, M; Liu, W; Yu, Y; Zhu, YS | 1 |
| Darzynkiewicz, Z; Del Bino, G; Li, X; Traganos, F | 1 |
| Jakob, F; Köhrle, J; Sarrazin, C; Schneider, D; Seufert, J; Tony, HP | 1 |
| Darzynkiewicz, Z; Gorczyca, W; Melamed, MR; Pizzolo, JG; Qiao, L | 1 |
| Boothman, DA; Church, DR; Frydman, B; Hutson, P; Planchon, SM; Wilding, G; Witiak, DT; Wuerzberger, S | 1 |
| Bertrand, R; Jenkins, J; Pommier, Y; Solary, E | 1 |
| Kohn, KW; O'Connor, PM; Pommier, Y; Shimizu, T | 1 |
| Bicknell, GR; Cohen, GM; Snowden, RT | 1 |
| Darzynkiewicz, Z; Li, X; Traganos, F | 1 |
| Darzynkiewicz, Z; Gong, J; Traganos, F | 1 |
| Darzynkiewicz, Z; Gong, J; Hotz, MA; Traganos, F | 1 |
| Averboukh, L; Li, CJ; Pardee, AB | 1 |
| Darzynkiewicz, Z; Gong, J; Li, X | 1 |
| Bertrand, R; Kohn, KW; Pommier, Y; Solary, E | 1 |
| Nakamura, T; Ueda, T; Wano, Y; Yoshida, A | 1 |
| Ardelt, B; Darzynkiewicz, RJ; Darzynkiewicz, Z; Gong, J; Kapuscinski, J; Traganos, F | 1 |
| Darzynkiewicz, Z; Gorczyca, W; Lassota, P; Traganos, F | 1 |
| Shellhaas, JL; Zuckerman, SH | 1 |
| Bertrand, R; Cimoli, G; Schmitt, E; Steyaert, A | 1 |
| Ayabe, H; Darzynkiwicz, Z; Hara, S; Tagawa, Y | 1 |
| Baldini, G; Bareggi, R; Bortul, R; Grill, V; Martelli, AM; Narducci, P; Tabellini, G | 1 |
| Pandolfi, PP; Rasheed, ZA; Ravee, Y; Rubin, EH; Saleem, A | 1 |
| Bruno, S; Darzynkiewicz, Z; Gorczyca, W; Melamed, MR | 1 |
| Ling, YH; Nelson, JA; Tseng, MT | 1 |
| Kaufmann, SH | 1 |
| Andersson, BS; Ling, YH; Nelson, JA | 1 |
| Cross, SM; Gorsky, LD; Morin, MJ | 1 |
31 other study(ies) available for camptothecin and Leukemia, Promyelocytic, Acute
| Article | Year |
|---|---|
Antitumor effects with apoptotic death in human promyelocytic leukemia HL-60 cells and suppression of leukemia xenograft tumor growth by irinotecan HCl.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Camptothecin; Caspase 3; Cell Cycle Proteins; Disease Models, Animal; DNA Damage; Endoplasmic Reticulum Chaperone BiP; G1 Phase Cell Cycle Checkpoints; HL-60 Cells; Humans; Irinotecan; Leukemia, Promyelocytic, Acute; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Confocal; Transplantation, Heterologous | 2015 |
Synergistic Leukemia Eradication by Combined Treatment with Retinoic Acid and HIF Inhibition by EZN-2208 (PEG-SN38) in Preclinical Models of PML-RARα and PLZF-RARα-Driven Leukemia.
Topics: Animals; Arsenic Trioxide; Arsenicals; Camptothecin; Cell Differentiation; Cell Movement; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Leukemia, Promyelocytic, Acute; Mice; Mutation; Neoplasm Proteins; Oncogene Proteins, Fusion; Oxides; Polyethylene Glycols; Tretinoin | 2015 |
Critical role of presenilin-dependent γ-secretase activity in DNA damage-induced promyelocytic leukemia protein expression and apoptosis.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Apoptosis; Brain; Camptothecin; Carbamates; Cell Line; Dipeptides; DNA Damage; Gene Expression; Gene Knockout Techniques; HEK293 Cells; Humans; Leukemia, Promyelocytic, Acute; Mice; Nuclear Proteins; Presenilins; Promyelocytic Leukemia Protein; RNA Interference; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Transcription Factors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Up-Regulation | 2013 |
Secondary acute promyelocytic leukemia following irinotecan and oxaliplatin for advanced colon cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Female; Humans; Irinotecan; Leukemia, Promyelocytic, Acute; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin | 2006 |
Therapeutic efficacy of NSC606985, a novel camptothecin analog, in a mouse model of acute promyelocytic leukemia.
Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Disease Models, Animal; Leukemia, Promyelocytic, Acute; Mice | 2007 |
Altered susceptibility of differentiating HL-60 cells to apoptosis induced by antitumor drugs.
Topics: Antineoplastic Agents; Apoptosis; Azacitidine; Camptothecin; Cell Cycle; Cell Differentiation; Dimethyl Sulfoxide; DNA, Neoplasm; Humans; Hyperthermia, Induced; Leukemia, Promyelocytic, Acute; Nuclear Proteins; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 1994 |
Topoisomerase I-inhibition enhances vitamin D-responsive expression of the receptor for lipopolysaccharide binding protein CD 14.
Topics: Acute-Phase Proteins; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Calcitriol; Camptothecin; Carrier Proteins; Cell Line; Cell Nucleus; Dose-Response Relationship, Drug; Flow Cytometry; Gene Expression; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Lipopolysaccharide Receptors; Membrane Glycoproteins; RNA, Messenger; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1994 |
Flow cytometric characterization of proliferation-associated nuclear antigen (p105) during the cell cycle in normal lymphocytes and promyelocytic leukemia cells (HL-60).
Topics: Camptothecin; Cell Cycle; Cycloheximide; DNA Damage; DNA, Neoplasm; Flow Cytometry; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Lymphocyte Activation; Lymphocytes; Methotrexate; Phytohemagglutinins; Proliferating Cell Nuclear Antigen; Teniposide; Vinblastine | 1995 |
Beta-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: a p53-independent response.
Topics: Apoptosis; Breast Neoplasms; Camptothecin; Cell Division; Dimethyl Sulfoxide; Drug Screening Assays, Antitumor; G1 Phase; Humans; Leukemia, Promyelocytic, Acute; Male; Naphthoquinones; Prostatic Neoplasms; Resting Phase, Cell Cycle; Time Factors; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1995 |
Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminoquinolines; Aphidicolin; Apoptosis; Benzamides; Calcium; Calmodulin; Camptothecin; Cell Cycle; Chromatin; Cyclosporine; DNA; Egtazic Acid; Ethers, Cyclic; Humans; Isoquinolines; Leukemia, Experimental; Leukemia, Promyelocytic, Acute; Microscopy, Electron; Naphthalenes; Okadaic Acid; Phosphoprotein Phosphatases; Piperazines; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Polycyclic Compounds; Protein Kinase C; Spermine; Staurosporine; Teniposide; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Zinc | 1993 |
Unscheduled activation of cyclin B1/Cdc2 kinase in human promyelocytic leukemia cell line HL60 cells undergoing apoptosis induced by DNA damage.
Topics: Aphidicolin; Apoptosis; Camptothecin; CDC2 Protein Kinase; Cyclins; DNA Damage; Enzyme Activation; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Mechlorethamine; Phosphorylation; S Phase; Tumor Cells, Cultured | 1995 |
Formation of high molecular mass DNA fragments is a marker of apoptosis in the human leukaemic cell line, U937.
Topics: Apoptosis; Biomarkers; Camptothecin; Cycloheximide; Dactinomycin; DNA Damage; DNA, Neoplasm; Emetine; Flow Cytometry; Humans; Leukemia, Promyelocytic, Acute; Molecular Weight; Neoplasm Proteins; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Zinc | 1994 |
Simultaneous analysis of DNA replication and apoptosis during treatment of HL-60 cells with camptothecin and hyperthermia and mitogen stimulation of human lymphocytes.
Topics: Apoptosis; Bromodeoxyuridine; Camptothecin; DNA Replication; DNA, Neoplasm; Humans; Hyperthermia, Induced; Idoxuridine; Leukemia, Promyelocytic, Acute; Lymphocyte Activation; Tumor Cells, Cultured | 1994 |
A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry.
Topics: Apoptosis; Bone Marrow; Camptothecin; DNA, Neoplasm; Electrophoresis; Ethanol; Flow Cytometry; Humans; Leukemia; Leukemia, Promyelocytic, Acute; Time Factors; Tumor Cells, Cultured | 1994 |
Flow cytometric detection of apoptosis: comparison of the assays of in situ DNA degradation and chromatin changes.
Topics: Apoptosis; Camptothecin; Chromosomes; DNA Damage; DNA, Neoplasm; Flow Cytometry; Fluorescent Dyes; G1 Phase; Humans; Indoles; Leukemia, Promyelocytic, Acute; Propidium; S Phase; Tumor Cells, Cultured | 1994 |
beta-Lapachone, a novel DNA topoisomerase I inhibitor with a mode of action different from camptothecin.
Topics: Animals; Camptothecin; Cattle; Cell Line; DNA, Kinetoplast; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Models, Structural; Molecular Structure; Naphthoquinones; Nucleic Acid Conformation; Plasmids; Protein Binding; Substrate Specificity; Thymus Gland; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1993 |
Different patterns of apoptosis of HL-60 cells induced by cycloheximide and camptothecin.
Topics: Apoptosis; Camptothecin; Cell Cycle; Cycloheximide; Electrophoresis, Agar Gel; Flow Cytometry; Humans; Leukemia, Promyelocytic, Acute; S Phase; Tosyllysine Chloromethyl Ketone; Tumor Cells, Cultured | 1993 |
Differential induction of apoptosis in undifferentiated and differentiated HL-60 cells by DNA topoisomerase I and II inhibitors.
Topics: Amsacrine; Apoptosis; Camptothecin; Cell Differentiation; DNA; DNA Damage; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tretinoin; Tumor Cells, Cultured | 1993 |
DNA damage and cell killing by camptothecin and its derivative in human leukemia HL-60 cells.
Topics: Camptothecin; Cell Death; DNA Damage; DNA Repair; DNA, Neoplasm; DNA, Single-Stranded; Humans; Irinotecan; Leukemia, Promyelocytic, Acute; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Zinc | 1993 |
Caffeine prevents apoptosis and cell cycle effects induced by camptothecin or topotecan in HL-60 cells.
Topics: Antineoplastic Agents; Apoptosis; Caffeine; Camptothecin; Cell Cycle; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Topotecan; Tumor Cells, Cultured | 1993 |
Altered sensitivity of DNA in situ to denaturation in apoptotic cells.
Topics: Apoptosis; Camptothecin; DNA, Neoplasm; Electrophoresis, Agar Gel; Flow Cytometry; Leukemia, Promyelocytic, Acute; Molecular Weight; Nucleic Acid Denaturation; S Phase; Tumor Cells, Cultured | 1993 |
In vitro detection of apoptotic stimuli by use of the HL-60 myeloid leukemic cell line.
Topics: Apoptosis; Camptothecin; DNA, Neoplasm; Enzyme-Linked Immunosorbent Assay; fas Receptor; Flow Cytometry; Humans; Leukemia, Promyelocytic, Acute; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1995 |
Bcl-xL modulates apoptosis induced by anticancer drugs and delays DEVDase and DNA fragmentation-promoting activities.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-X Protein; Camptothecin; Cell-Free System; Cysteine Proteinase Inhibitors; DNA Fragmentation; Endopeptidases; Enzyme Activation; Humans; Leukemia, Promyelocytic, Acute; Oligopeptides; Peptide Hydrolases; Proto-Oncogene Proteins c-bcl-2; Serine Proteinase Inhibitors; Tosylphenylalanyl Chloromethyl Ketone; Transfection; Tumor Cells, Cultured | 1998 |
[Analysis of drug-induced apoptosis in human leukemic cell line (HL-60)].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Azacitidine; Camptothecin; Cell Cycle; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Tosylphenylalanyl Chloromethyl Ketone | 1998 |
The pro-apoptotic drug camptothecin stimulates phospholipase D activity and diacylglycerol production in the nucleus of HL-60 human promyelocytic leukemia cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Diglycerides; Enzyme Activation; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Phospholipase D | 1999 |
The topoisomerase I-binding RING protein, topors, is associated with promyelocytic leukemia nuclear bodies.
Topics: Amino Acid Sequence; Animals; Binding Sites; Camptothecin; Carrier Proteins; Cell Nucleus; Chromosome Mapping; Dichlororibofuranosylbenzimidazole; Dimethyl Sulfoxide; DNA Topoisomerases, Type I; DNA-Binding Proteins; HeLa Cells; Humans; Leukemia, Promyelocytic, Acute; Mice; Molecular Sequence Data; Neoplasm Proteins; Nuclear Proteins; Nucleic Acid Synthesis Inhibitors; Promyelocytic Leukemia Protein; Rabbits; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Topoisomerase I Inhibitors; Transcription Factors; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Zinc Fingers | 2002 |
Cell cycle-related expression of p120 nucleolar antigen in normal human lymphocytes and in cells of HL-60 and MOLT-4 leukemic lines: effects of methotrexate, camptothecin, and teniposide.
Topics: Antigens, Neoplasm; Camptothecin; Cell Cycle; Humans; Leukemia, Promyelocytic, Acute; Lymphocytes; Methotrexate; Nuclear Proteins; Teniposide; tRNA Methyltransferases; Tumor Cells, Cultured; Vinblastine | 1992 |
Differentiation induction of human promyelocytic leukemia cells by 10-hydroxycamptothecin, a DNA topoisomerase I inhibitor.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Differentiation; DNA Topoisomerases, Type I; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; RNA, Neoplasm; Time Factors; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1991 |
Antagonism between camptothecin and topoisomerase II-directed chemotherapeutic agents in a human leukemia cell line.
Topics: Amsacrine; Aphidicolin; Blotting, Western; Camptothecin; Colony-Forming Units Assay; Cycloheximide; Daunorubicin; Deoxyadenosines; Dichlororibofuranosylbenzimidazole; Diterpenes; DNA Polymerase II; DNA Replication; Drug Synergism; Etoposide; Female; Humans; Leukemia, Promyelocytic, Acute; Mutagens; RNA; Topoisomerase II Inhibitors; Topotecan; Tumor Cells, Cultured | 1991 |
DNA topoisomerase I as a site of action for 10-hydroxycamptothecin in human promyelocytic leukemia cells.
Topics: Amsacrine; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Division; DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Resistance; Enzyme Inhibitors; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Mutation; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1990 |
Rapid increase in the activity of DNA topoisomerase I, but not topoisomerase II, in HL-60 promyelocytic leukemia cells treated with a phorbol diester.
Topics: Camptothecin; Cell Line; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Enzyme Activation; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |