camptothecin has been researched along with Leukemia, Myeloid in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.57) | 18.7374 |
| 1990's | 16 (57.14) | 18.2507 |
| 2000's | 9 (32.14) | 29.6817 |
| 2010's | 2 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cui, L; Ji, Q; Kai, G; Ni, X; Teng, X; Wu, C; Yang, Y; Zekria, D; Zhang, D | 1 |
| Chen, GQ; Cheng, JK; Shen, SM; Wang, LS; Wu, YL; Yu, Y | 1 |
| Cortes, JE; De Jager, RL; Faderl, S; Garcia-Manero, G; Giles, FJ; Jeha, S; Kantarjian, HM; Thomas, DA | 1 |
| Bates, PJ; Casson, LK; Mi, Y; Miller, DM; Thomas, SD; Xu, X | 1 |
| Albitar, M; Barrett, E; Cortes, JE; Garcia-Manero, G; Giles, FJ; Hamilton, M; Kantarjian, HM; Tallman, MS; Thomas, DA; Verstovsek, S; Wierda, WG | 1 |
| Haskovec, C; Ullmannová, V | 1 |
| Adams, DJ; Colvin, OM; Flowers, JL; Rizzieri, DA; Shanks, RH | 1 |
| Baer, MR; Ford, LA; Greco, WR; Minderman, H; O'Loughlin, KL; Pendyala, L; Smith, PF; Sweeney, KG; Wetzler, M | 1 |
| Kataoka, S; Kawai, H; Mashima, T; Naito, M; Tsuruo, T | 1 |
| Hashimoto, S; Jing, Y; Nakajo, S; Nakaya, K | 1 |
| Bharti, A; Giovanella, B; Kufe, D; Pantazis, P; Rubin, E; Toppmeyer, D | 1 |
| Early, JA; Giovanella, BC; Kozielski, AJ; Mendoza, JT; Natelson, EA; Pantazis, P | 1 |
| Emoto, Y; Kharbanda, S; Kisaki, H; Kufe, D; Manome, Y | 1 |
| Abiko, Y; Shibata, Y; Takiguchi, H; Tamura, K; Tezuka, M; Yamanaka, K | 1 |
| Crump, M; Hedley, DW; Nicklee, T | 1 |
| Mashima, T; Miller, DK; Naito, M; Nicholson, DW; Noguchi, K; Tsuruo, T | 1 |
| DeJesus, A; Early, J; Giovanella, B; Pantazis, P | 1 |
| Beran, M; Jeha, S; Kantarjian, H; O'Brien, S; Vitek, L | 1 |
| Barbier, M; Boutonnat, J; Grunwald, D; Mousseau, M; Muirhead, K; Ronot, X; Seigneurin, D | 1 |
| Bargonetti, J; Gopen, T; Houser, S; Koshlatyi, S; Lu, T | 1 |
| Chauvier, D; Manfait, M; Morjani, H | 1 |
| Aller, P; Bellón, T; Bernabeu, C; Cabañas, C; Mata, F; Rius, C; Zorrilla, A | 1 |
| Giovanella, B; Gunji, H; Hinz, H; Kharbanda, S; Kufe, D; Pantazis, P; Rubin, E | 1 |
| Chou, S; Kaneko, M; Nakamura, Y; Nakaya, K | 1 |
| Darzynkiewicz, Z; Del Bino, G; Lassota, P | 1 |
| Darzynkiewicz, Z; Del Bino, G | 1 |
| Darzynkiewicz, Z; Del Bino, G; Skierski, JS | 1 |
| Hamada, H; Naito, M; Tsuruo, T | 1 |
3 trial(s) available for camptothecin and Leukemia, Myeloid
| Article | Year |
|---|---|
Phase I and pharmacokinetic study of DX-8951f (exatecan mesylate), a hexacyclic camptothecin, on a daily-times-five schedule in patients with advanced leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy; Stomatitis; Topoisomerase I Inhibitors | 2002 |
Phase I and pharmacokinetic study of a low-clearance, unilamellar liposomal formulation of lurtotecan, a topoisomerase 1 inhibitor, in patients with advanced leukemia.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Area Under Curve; Camptothecin; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid; Male; Metabolic Clearance Rate; Middle Aged; Mouth Mucosa; Topoisomerase I Inhibitors; Treatment Outcome | 2004 |
Sequential administration of irinotecan and cytarabine in the treatment of relapsed and refractory acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cytarabine; DNA Damage; DNA Topoisomerases, Type I; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Synergism; Female; HL-60 Cells; Humans; Irinotecan; Leukemia, Myeloid; Male; Middle Aged; Recurrence | 2006 |
25 other study(ies) available for camptothecin and Leukemia, Myeloid
| Article | Year |
|---|---|
Co-overexpression of geraniol-10-hydroxylase and strictosidine synthase improves anti-cancer drug camptothecin accumulation in Ophiorrhiza pumila.
Topics: Antineoplastic Agents, Phytogenic; Biosynthetic Pathways; Camptothecin; Carbon-Nitrogen Lyases; Cell Line, Tumor; Cell Survival; Cytochrome P-450 Enzyme System; Gene Expression; Humans; Leukemia, Myeloid; Plant Roots; Plants, Genetically Modified; Rubiaceae; Transcription, Genetic | 2015 |
Downregulation of ANP32B, a novel substrate of caspase-3, enhances caspase-3 activation and apoptosis induction in myeloid leukemic cells.
Topics: Acetophenones; Antineoplastic Agents; Apoptosis; Benzopyrans; Camptothecin; Carcinoma; Caspase 3; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Down-Regulation; Enzyme Activation; Female; Humans; Leukemia, Myeloid; Male; Neoplasm Proteins; Neoplasms; Nuclear Proteins; Recombinant Fusion Proteins; RNA Interference; RNA, Small Interfering; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity | 2010 |
Apoptosis in leukemia cells is accompanied by alterations in the levels and localization of nucleolin.
Topics: Apoptosis; Benzamides; Camptothecin; Enzyme Inhibitors; Humans; In Situ Nick-End Labeling; Leukemia, Myeloid; Nucleolin; Phosphoproteins; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Precipitin Tests; RNA-Binding Proteins; U937 Cells; Ultraviolet Rays | 2003 |
Gene expression during camptothecin-induced apoptosis in human myeloid leukemia cell line ML-2.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Camptothecin; Cell Cycle; Cell Differentiation; Cell Division; Down-Regulation; Gene Expression Profiling; Humans; Leukemia, Myeloid; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2004 |
Preclinical evaluation of gemcitabine combination regimens for application in acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Agents; Apoptosis; Camptothecin; Caspase 3; Caspase 7; Caspases; Cell Cycle; Chlorambucil; Deoxycytidine; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation, Preclinical; Drug Interactions; Enzyme Activation; Flow Cytometry; Gemcitabine; Humans; Irinotecan; Leukemia, Myeloid; Mitoxantrone; Paclitaxel; U937 Cells; Vidarabine | 2005 |
Aspartate-based inhibitor of interleukin-1 beta-converting enzyme prevents antitumor agent-induced apoptosis in human myeloid leukemia U937 cells.
Topics: Antineoplastic Agents; Apoptosis; Aspartic Acid; Camptothecin; Caspase 1; Cell Cycle; Cell Line; Cysteine Endopeptidases; Cytarabine; DNA, Neoplasm; Doxorubicin; Etoposide; Humans; Kinetics; Leukemia, Myeloid; Time Factors; Tumor Cells, Cultured | 1995 |
Topoisomerase inhibitors potentiate the effect of retinoic acid on cell growth inhibition and induction of differentiation of leukemia HL-60 cells.
Topics: Camptothecin; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Cycle; Cell Differentiation; DNA, Neoplasm; Drug Synergism; Etoposide; Growth Inhibitors; Humans; In Vitro Techniques; Leukemia, Myeloid; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tretinoin; Tumor Cells, Cultured | 1994 |
Identification of a mutant human topoisomerase I with intact catalytic activity and resistance to 9-nitro-camptothecin.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Base Sequence; Camptothecin; Cell Line; Cell Nucleus; Cell Survival; Clone Cells; Codon; DNA Primers; DNA Topoisomerases, Type I; DNA, Complementary; Drug Resistance; Humans; Kinetics; Leukemia, Myeloid; Mice; Molecular Sequence Data; Molecular Weight; Point Mutation; Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Tumor Cells, Cultured | 1994 |
9-Nitro-camptothecin delays growth of U-937 leukemia tumors in nude mice and is cytotoxic or cytostatic for human myelomonocytic leukemia lines in vitro.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Cycle; Cell Death; DNA, Neoplasm; Growth Inhibitors; Humans; In Vitro Techniques; Leukemia, Experimental; Leukemia, Myeloid; Mice; Mice, Nude; Neoplasm Transplantation; Tumor Cells, Cultured | 1993 |
Activation of protein kinase Cdelta in human myeloid leukemia cells treated with 1-beta-D-arabinofuranosylcytosine.
Topics: Amino Acid Sequence; Apoptosis; Camptothecin; Cytarabine; DNA Damage; Endopeptidases; Enzyme Activation; Genes, jun; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; Leukemia, Myeloid; Lymphoma, Large B-Cell, Diffuse; Membrane Proteins; Mitomycin; Molecular Sequence Data; Myelin Basic Protein; Myristoylated Alanine-Rich C Kinase Substrate; Neoplasm Proteins; Neoplastic Stem Cells; Nucleosomes; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Processing, Post-Translational; Proteins; Signal Transduction; Substrate Specificity; Tumor Cells, Cultured | 1996 |
Stimulation of interleukin-1beta-converting enzyme activity during growth inhibition by CPT-11 in the human myeloid leukemia cell line K562.
Topics: Apoptosis; Base Sequence; Camptothecin; Caspase 1; Cysteine Endopeptidases; Gene Expression Regulation, Leukemic; Humans; In Situ Hybridization; Irinotecan; Leukemia, Myeloid; Molecular Sequence Data; Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 1996 |
Effects of topoisomerase I inhibition on the expression of topoisomerase II alpha measured with fluorescence image cytometry.
Topics: Animals; Antibody Specificity; Camptothecin; Cell Cycle; DNA Topoisomerases, Type II; Enzyme Inhibitors; Fluorescence; Humans; Image Cytometry; Leukemia, Myeloid; Rabbits; Topoisomerase I Inhibitors; Topotecan; Tumor Cells, Cultured | 1996 |
Actin cleavage by CPP-32/apopain during the development of apoptosis.
Topics: Actins; Apoptosis; Camptothecin; Caspase 1; Caspase 3; Caspases; Cysteine Endopeptidases; Etoposide; Humans; Leukemia, Myeloid; Oligopeptides; Protease Inhibitors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Altered sensitivities to anticancer and differentiation agents in etoposide-resistant human myeloid leukemia U-937 cells.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Camptothecin; Cell Differentiation; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Humans; Leukemia, Myeloid; Lymphotoxin-alpha; Mice; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
Activity of oral and intravenous 9-aminocamptothecin in SCID mice engrafted with human leukemia.
Topics: Acute Disease; Administration, Oral; Animals; Camptothecin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; HLA-DQ alpha-Chains; HLA-DQ Antigens; Humans; Injections, Intravenous; Leukemia, Experimental; Leukemia, Myeloid; Mice; Mice, SCID; Neoplasm Transplantation; Survival Rate | 1998 |
Response of chemosensitive and chemoresistant leukemic cell lines to drug therapy: simultaneous assessment of proliferation, apoptosis, and necrosis.
Topics: Annexin A5; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Camptothecin; Cell Division; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescent Dyes; Humans; Irinotecan; Leukemia, Myeloid; Necrosis; Propidium; Tranexamic Acid; Tumor Cells, Cultured; Vincristine | 2000 |
Camptothecin and Zeocin can increase p53 levels during all cell cycle stages.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Bleomycin; Camptothecin; Cell Cycle; DNA Damage; DNA, Neoplasm; Drug Stability; Humans; Leukemia, Myeloid; Phosphorylation; Serine; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
Homocamptothecin-daunorubicin association overcomes multidrug-resistance in breast cancer MCF7 cells.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Camptothecin; Carcinoma; Colonic Neoplasms; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Leukemia, Myeloid; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Polymerase Chain Reaction; RNA, Neoplasm; Treatment Outcome; Tumor Cells, Cultured | 2002 |
Camptothecin induces differentiation and stimulates the expression of differentiation-related genes in U-937 human promonocytic leukemia cells.
Topics: Camptothecin; Cell Differentiation; DNA, Neoplasm; Eflornithine; Gene Expression Regulation, Leukemic; Genes, myc; Humans; Hydrogen Peroxide; Integrins; Leukemia, Myeloid; RNA, Messenger; Tumor Cells, Cultured; Vimentin | 1992 |
Camptothecin and its derivatives induce expression of the c-jun protooncogene in human myeloid leukemia cells.
Topics: Camptothecin; Cell Division; DNA Damage; Gene Expression; Genes, fos; Genes, jun; Humans; In Vitro Techniques; Leukemia, Myeloid; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic; Tumor Cells, Cultured | 1991 |
Topoisomerase inhibitors have potent differentiation-inducing activity for human and mouse myeloid leukemia cells.
Topics: Animals; Biomarkers, Tumor; Camptothecin; Cell Differentiation; DNA; DNA Damage; Drug Synergism; Etoposide; Humans; In Vitro Techniques; Leukemia, Myeloid; Mice; Time Factors; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1991 |
The S-phase cytotoxicity of camptothecin.
Topics: Camptothecin; Cell Cycle; Cell Nucleus; DNA, Neoplasm; Electrophoresis, Agar Gel; Flow Cytometry; Fluorescent Dyes; Humans; Indoles; Leukemia, Myeloid; Lysosomes; Mitochondria; S Phase; Time Factors; Tumor Cells, Cultured | 1991 |
Camptothecin, teniposide, or 4'-(9-acridinylamino)-3-methanesulfon-m-anisidide, but not mitoxantrone or doxorubicin, induces degradation of nuclear DNA in the S phase of HL-60 cells.
Topics: Amsacrine; Camptothecin; Cell Line; DNA; Doxorubicin; Humans; In Vitro Techniques; Leukemia, Myeloid; Mitoxantrone; S Phase; Teniposide | 1991 |
Diverse effects of camptothecin, an inhibitor of topoisomerase I, on the cell cycle of lymphocytic (L1210, MOLT-4) and myelogenous (HL-60, KG1) leukemic cells.
Topics: Animals; Camptothecin; DNA, Neoplasm; Humans; Interphase; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid; Mice; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1990 |
ATP/Mg2+-dependent binding of vincristine to the plasma membrane of multidrug-resistant K562 cells.
Topics: Adenosine Triphosphate; Binding Sites; Biological Transport; Camptothecin; Cell Membrane; Dactinomycin; Doxorubicin; Drug Resistance; Fluorouracil; Kinetics; Leukemia, Myeloid; Magnesium; Tumor Cells, Cultured; Verapamil; Vinblastine; Vincristine | 1988 |