camptothecin has been researched along with Leukemia, Myeloid, Acute in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 10 (62.50) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akiyama, H; Kurosu, T; Miura, O; Murakami, N; Sakashita, C; Umezawa, Y; Yamamoto, M | 1 |
| Bredholt, T; Dimba, EA; Fossan, KO; Gjertsen, BT; Hagland, HR; Johannessen, AC; Skavland, J; Tronstad, KJ; Vintermyr, OK; Wergeland, L | 1 |
| Bourhis, JH; Damaj, G; Dreyfus, F; Fenaux, P; Feremans, W; Guerci, A; Ravoet, C; Ribrag, V; Suzan, F; Vantelon, JM | 1 |
| Bendele, R; Brown, E; Emerson, DL; Giles, FJ; Gray, A; Hart, K; LeRay, JD; Meyer, D; Pelanne, M; Tomkinson, B | 1 |
| Baer, MR; Conroy, JM; Li, S; McQuaid, D; Minderman, H; Nowak, NJ; O'Loughlin, KL; Pendyala, L; Quinn, P | 1 |
| Caron, P; Liu, D; Patel, S; Seiter, K | 1 |
| Chen, GQ; Shen, SM; Wang, LS; Xia, L; Yu, Y; Zhang, L; Zhu, YS | 1 |
| Masaoka, T; Ohashi, Y; Ohno, R; Okada, K; Ota, K; Shirakawa, S; Taguchi, T | 1 |
| Ariyoshi, Y; Furue, H; Kimura, I; Masaoka, T; Ogawa, M; Oguro, M; Ohno, R; Saito, H; Sakai, Y; Yoshida, Y | 1 |
| Ahmed, T; Darzynkiewicz, Z; Feldman, EJ; Halicka, HD; Lake, D; Seiter, K; Traganos, F | 1 |
| Arbuck, S; Beran, M; Bivins, C; Cheson, B; Cortes, J; Estey, E; Giles, F; Kantarjian, H; O'Brien, S; Tran, H; Vey, N | 1 |
| Austin, CA; Carr, R; Padget, K; Pearson, AD; Tilby, MJ | 1 |
| Beran, M; Giles, FJ; Jeha, S; Kantarjian, H; Smith, TL; Vey, N | 1 |
| Choi, CH; Chung, MH; Jeong, JH; Kim, HS; Kim, MS; Kweon, OS; Lee, TB; Lim, DY; Min, YD; Rha, HS; You, HJ | 1 |
| Cortes, J; Estey, E; Garcia-Manero, G; Giles, F; Kantarjian, H; Kornblau, S; Kwari, M; Murgo, A | 1 |
| Kaufmann, SH | 1 |
5 trial(s) available for camptothecin and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Phase II trial of CPT-11 in myelodysplastic syndromes with excess of marrow blasts.
Topics: Aged; Anemia, Refractory, with Excess of Blasts; Antineoplastic Agents, Phytogenic; Blast Crisis; Bone Marrow; Camptothecin; Disease Progression; Female; Humans; Infusions, Intravenous; Irinotecan; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Survival Analysis; Time Factors | 2003 |
[Late phase II clinical study of irinotecan hydrochloride (CPT-11) in the treatment of malignant lymphoma and acute leukemia. The CPT-11 Research Group for Hematological Malignancies].
Topics: Adolescent; Adult; Aged; Anorexia; Antineoplastic Agents, Phytogenic; Camptothecin; Diarrhea; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Irinotecan; Leukemia, Myeloid, Acute; Leukemia, T-Cell; Lymphoma, Non-Hodgkin; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1994 |
[An early phase II study of CPT-11 (irinotecan hydrochloride) in patients with hematological malignancies].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Diarrhea; Drug Administration Schedule; Female; Hodgkin Disease; Humans; Irinotecan; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Nausea; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1994 |
Phase I and pharmacologic study of 9-aminocamptothecin colloidal dispersion formulation in patients with refractory or relapsed acute leukemia.
Topics: Adult; Aged; Antineoplastic Agents; Camptothecin; Colloids; Humans; Leukemia, Myeloid, Acute; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1999 |
Phase I study of irofulven (MGI 114), an acylfulvene illudin analog, in patients with acute leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Camptothecin; Drug Administration Schedule; Hematologic Tests; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Maximum Tolerated Dose; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sesquiterpenes; Survival Rate | 2001 |
11 other study(ies) available for camptothecin and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Therapy-related leukemia with Inv(16)(p13.1q22) and type D CBFB/MYH11 developing after exposure to irinotecan-containing chemoradiotherapy.
Topics: Adult; Antineoplastic Agents, Phytogenic; Camptothecin; Chemoradiotherapy; Chromosomes, Human, Pair 16; Female; Humans; Irinotecan; Leukemia, Myeloid, Acute; Oncogene Proteins, Fusion; Treatment Outcome | 2015 |
Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines.
Topics: bcl-2-Associated X Protein; Camptothecin; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 8; Catha; Cell Death; Cell Line, Tumor; Cell Respiration; Cytoprotection; Drug Screening Assays, Antitumor; Enzyme Activation; Humans; Leukemia, Myeloid, Acute; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Phenotype; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-bcl-2 | 2009 |
OSI-211, a novel liposomal topoisomerase I inhibitor, is active in SCID mouse models of human AML and ALL.
Topics: Animals; Antineoplastic Agents; Camptothecin; Disease Models, Animal; Drug Evaluation; Female; Humans; Leukemia, Myeloid, Acute; Mice; Mice, SCID; Neoplasm Transplantation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation, Heterologous; Tumor Cells, Cultured | 2003 |
In vitro and in vivo irinotecan-induced changes in expression profiles of cell cycle and apoptosis-associated genes in acute myeloid leukemia cells.
Topics: Apoptosis; Camptothecin; Cell Cycle; Cluster Analysis; DNA, Complementary; Down-Regulation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Irinotecan; Kinetics; Leukemia, Myeloid, Acute; Oligonucleotide Array Sequence Analysis; Reproducibility of Results; RNA, Messenger; Transcription, Genetic; Up-Regulation | 2005 |
Acute myelogenous leukemia following irinotecan-based chemotherapy for adenocarcinoma of the small intestine.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Fluorouracil; Humans; Intestinal Neoplasms; Intestine, Small; Irinotecan; Leucovorin; Leukemia, Myeloid, Acute; Male; Prognosis; Recurrence; Remission Induction | 2007 |
Subcellular proteome analysis of camptothecin analogue NSC606985-treated acute myeloid leukemic cells.
Topics: Apoptosis; Camptothecin; Cell Line, Tumor; Electrophoresis, Gel, Two-Dimensional; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Protein Kinase C-delta; Proteome; Proteomics; Subcellular Fractions | 2007 |
Phase I clinical and laboratory evaluation of topotecan and cytarabine in patients with acute leukemia.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blast Crisis; Camptothecin; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Topotecan | 1997 |
Camptothecin-stabilised topoisomerase I-DNA complexes in leukaemia cells visualised and quantified in situ by the TARDIS assay (trapped in agarose DNA immunostaining).
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; DNA; DNA Topoisomerases, Type I; Fluorescent Antibody Technique; Humans; K562 Cells; Leukemia, Myeloid, Acute; Tumor Cells, Cultured | 2000 |
The topoisomerase I inhibitor DX-8951f is active in a severe combined immunodeficient mouse model of human acute myelogenous leukemia.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Female; Humans; Leukemia, Myeloid, Acute; Mice; Mice, SCID; Survival Analysis; Time Factors; Topoisomerase I Inhibitors; Transplantation, Heterologous; Tumor Cells, Cultured | 2000 |
Reactive oxygen species-specific mechanisms of drug resistance in paraquat-resistant acute myelogenous leukemia sublines.
Topics: Alkynes; Antineoplastic Agents; Camptothecin; Cell Survival; Cisplatin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Glutathione Transferase; Glycine; Humans; Leukemia, Myeloid, Acute; Metallothionein; Paraquat; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Superoxide Dismutase; Tumor Cells, Cultured; Vincristine | 2000 |
Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note.
Topics: Antineoplastic Agents; Camptothecin; Cell Line; Cell Nucleus; Dinitrophenols; DNA Damage; DNA, Neoplasm; Etoposide; Humans; Kinetics; Leukemia, Myeloid, Acute; Nuclear Proteins; Tumor Cells, Cultured | 1989 |