Page last updated: 2024-08-22

camptothecin and Experimental Mammary Neoplasms

camptothecin has been researched along with Experimental Mammary Neoplasms in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's8 (27.59)18.2507
2000's7 (24.14)29.6817
2010's12 (41.38)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Hwang, SY; Jeon, YH; Jeong, TC; Jo, H; Kadayat, TM; Katila, P; Kim, KS; Kim, SK; Koh, WS; Kwon, Y; Lee, ES; Nepal, MR; Noh, K; Park, S; Shrestha, A; Shrestha, R1
Chen, Q; Cui, H; Qian, M; Wang, J; Zeng, S; Zhang, L1
Guo, X; Jing, Y; Ming, Y; Xiong, X; Yang, G; Zhao, J; Zhou, S1
Hou, C; Jia, D; Kang, Y; Lu, Y; Ma, X; Wang, Y; Xu, Z; Xue, P; Zhang, T; Zu, M1
Cheng, L; Feng, L; Gong, H; Gu, X; Liu, T; Liu, Z; Shi, X; Sun, B; Wang, C1
Atyabi, F; Dinarvand, R; Ghahremani, MH; Khoshayand, MR; Montazeri, H; Ostad, SN; Rouhani, H; Sepehri, N; Tavassolian, F1
Baker, TL; Burnett, JP; Clouthier, SG; Conley, SJ; Eliasof, S; Lazarus, D; Peters, CG; Theisen, RL; Wicha, MS1
Bateman, E; Keefe, D; Mayo, B; Stringer, A; Thorpe, D; Vanhoecke, B; Vanlancker, E1
Chia, WT; Chung, MF; Lin, KJ; Liu, HY; Sung, HW1
Cui, H; Lock, LL; Mao, W; Shen, Y; Sui, M; Sun, W; Tang, J; Wang, J; Xu, D1
Abe, Y; Ashida, S; Honda, T; Kasuya, Y; Masuda, T; Miyazaki, H; Morita, K; Naito, H; Nakada, T; Ogitani, Y; Yamaguchi, J; Yoshida, M1
Bathula, SR; Conwell, C; Huang, L; Liu, F; Liu, Y; Park, JY; Zhang, Y1
Aboody, KS; Annala, AJ; Garcia, E; Gilchrist, M; Glackin, CA; Gutova, M; Kim, SU; Metz, MZ; Najbauer, J; Polewski, MD; Zhao, D1
Greenwald, RB; Xia, J; Zhao, H1
Balasubramanian, BN; Fairchild, CR; Jang, GR; Long, B; Marathe, PH; Monticello, TM; Rose, WC; Wall, ME; Wani, MC1
Kiselyov, A1
Bowen, JM; Cummins, AG; Gibson, RJ; Keefe, DM; Tyskin, A1
Herman, TS; Holden, SA; Khandakar, V; Teicher, BA1
Kirichenko, AV; Rich, TA; Travis, EL1
Tannock, IF; Vukovic, V1
Kirichenko, AV; Newman, RA; Rich, TA; Travis, EL1
Andoh, T; Aogi, K; Fujiwara, Y; Hirabayashi, N; Kim, R; Kusano, T; Mizutani, A; Nishiyama, M; Okada, K; Sumiyoshi, H; Toge, T; Yamakido, M1
Ara, G; Chan, V; Eder, JP; Northey, D; Rizvi, N; Teicher, BA; Wong, J; Wong, YW1
Brem, H; Ewend, MG; Sampath, P; Tyler, BM; Williams, JA1
Cvitkovic, E; Goldwasser, F; Raymond, E; Zeghari-Squalli, N1
Gilbert, BE; Giovanella, BC; Kleinerman, ES; Knight, V; Koshkina, NV; Waldrep, JC1
Chow, DS; Giovanella, BC; Gong, L; Wolfe, MD1
Kirichenko, AV; Rich, TA1
DiAngelo, S; Garg, LC; Jacob, ST1

Reviews

1 review(s) available for camptothecin and Experimental Mammary Neoplasms

ArticleYear
Dark Agouti rat model of chemotherapy-induced mucositis: establishment and current state of the art.
    Experimental biology and medicine (Maywood, N.J.), 2015, Volume: 240, Issue:6

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Fluorouracil; Humans; Irinotecan; Mammary Neoplasms, Experimental; Methotrexate; Mice; Mucositis; Rats

2015

Other Studies

28 other study(ies) available for camptothecin and Experimental Mammary Neoplasms

ArticleYear
Discovery and Biological Evaluations of Halogenated 2,4-Diphenyl Indeno[1,2-
    Journal of medicinal chemistry, 2019, 09-12, Volume: 62, Issue:17

    Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Breast Neoplasms; Cell Proliferation; Cell Survival; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Female; Humans; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred ICR; Microwaves; Molecular Structure; Pyridines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tumor Cells, Cultured

2019
Spatiotemporal Concurrent Liberation of Cytotoxins from Dual-Prodrug Nanomedicine for Synergistic Antitumor Therapy.
    ACS applied materials & interfaces, 2021, Feb-10, Volume: 13, Issue:5

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Cycle; Cell Proliferation; Cytotoxins; Drug Liberation; Drug Screening Assays, Antitumor; Female; Humans; Hydrogen-Ion Concentration; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Nanomedicine; Organoplatinum Compounds; Particle Size; Prodrugs; Surface Properties; Tumor Cells, Cultured

2021
A Multifunctional Micellar Nanoplatform with pH-Triggered Cell Penetration and Nuclear Targeting for Effective Cancer Therapy and Inhibition to Lung Metastasis.
    Advanced healthcare materials, 2018, Volume: 7, Issue:7

    Topics: A549 Cells; Animals; Camptothecin; Delayed-Action Preparations; Drug Carriers; Female; Humans; Hydrogen-Ion Concentration; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Nanoparticles; Neoplasm Metastasis

2018
Mitochondria-Specific Anticancer Drug Delivery Based on Reduction-Activated Polyprodrug for Enhancing the Therapeutic Effect of Breast Cancer Chemotherapy.
    ACS applied materials & interfaces, 2019, Aug-14, Volume: 11, Issue:32

    Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Camptothecin; Delayed-Action Preparations; Female; HeLa Cells; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice, Inbred BALB C; Micelles; Mitochondria; Prodrugs; Reactive Oxygen Species

2019
Drug delivery with PEGylated MoS2 nano-sheets for combined photothermal and chemotherapy of cancer.
    Advanced materials (Deerfield Beach, Fla.), 2014, Jun-04, Volume: 26, Issue:21

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Survival; Chlorophyllides; Combined Modality Therapy; Disulfides; Doxorubicin; Drug Carriers; Female; HeLa Cells; Humans; Irinotecan; KB Cells; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Molybdenum; Nanostructures; Phototherapy; Pilot Projects; Polyethylene Glycols; Porphyrins; Radiation-Sensitizing Agents

2014
SN38 polymeric nanoparticles: in vitro cytotoxicity and in vivo antitumor efficacy in xenograft balb/c model with breast cancer versus irinotecan.
    International journal of pharmaceutics, 2014, Aug-25, Volume: 471, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Liberation; Female; Humans; Irinotecan; Lactic Acid; Mammary Neoplasms, Experimental; Mice, Inbred BALB C; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Surface Properties; Tissue Distribution; Xenograft Model Antitumor Assays

2014
CRLX101, an investigational camptothecin-containing nanoparticle-drug conjugate, targets cancer stem cells and impedes resistance to antiangiogenic therapy in mouse models of breast cancer.
    Breast cancer research and treatment, 2015, Volume: 150, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cell Line, Tumor; Cyclodextrins; Drug Resistance, Neoplasm; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Neoplastic Stem Cells; Xenograft Model Antitumor Assays

2015
A pH-Responsive Carrier System that Generates NO Bubbles to Trigger Drug Release and Reverse P-Glycoprotein-Mediated Multidrug Resistance.
    Angewandte Chemie (International ed. in English), 2015, Aug-17, Volume: 54, Issue:34

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Camptothecin; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Hydrogen-Ion Concentration; Irinotecan; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Nude; Nitric Oxide

2015
The Role of Micelle Size in Tumor Accumulation, Penetration, and Treatment.
    ACS nano, 2015, Jul-28, Volume: 9, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Female; Humans; Irinotecan; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Micelles

2015
Novel antibody drug conjugates containing exatecan derivative-based cytotoxic payloads.
    Bioorganic & medicinal chemistry letters, 2016, Mar-15, Volume: 26, Issue:6

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Injections, Intraventricular; Mammary Neoplasms, Experimental; Mice; Molecular Conformation; Structure-Activity Relationship; Trastuzumab

2016
Targeted cancer therapy with novel high drug-loading nanocrystals.
    Journal of pharmaceutical sciences, 2010, Volume: 99, Issue:8

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Carrier Proteins; Chemistry, Pharmaceutical; Drug Delivery Systems; Excipients; Female; Folate Receptors, GPI-Anchored; Glycerol; Hemolysis; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron, Transmission; Nanoparticles; Neoplasm Transplantation; Neoplasms; Paclitaxel; Poloxamer; Receptors, Cell Surface; Surface-Active Agents

2010
Human neural stem cell tropism to metastatic breast cancer.
    Stem cells (Dayton, Ohio), 2012, Volume: 30, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biotransformation; Camptothecin; Carboxylesterase; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Delivery Systems; Female; Humans; Interleukin-6; Irinotecan; Lung Neoplasms; Lymphatic Metastasis; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasm Invasiveness; Neural Stem Cells; Prodrugs; Rabbits; Xenograft Model Antitumor Assays

2012
Tripartate poly(ethylene glycol) prodrugs of the open lactone form of camptothecin.
    Bioorganic & medicinal chemistry, 2003, Jun-12, Volume: 11, Issue:12

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Half-Life; Humans; Injections, Intravenous; Lactones; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasm Transplantation; Polyethylene Glycols; Prodrugs; Rats; Solubility

2003
Novel fluoro-substituted camptothecins: in vivo antitumor activity, reduced gastrointestinal toxicity and pharmacokinetic characterization.
    Cancer chemotherapy and pharmacology, 2006, Volume: 58, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Female; Gastrointestinal Tract; Humans; Irinotecan; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Mice, Nude; Ovarian Neoplasms; Prodrugs; Rats; Rats, Sprague-Dawley; Tumor Burden; Xenograft Model Antitumor Assays

2006
Drug Discovery Technology and Development 2005 - IBC's Tenth World Congress. Cancer mouse models and other techniques for improved prediction of efficacy.
    IDrugs : the investigational drugs journal, 2005, Volume: 8, Issue:10

    Topics: Angiogenesis Inhibitors; Animals; Boronic Acids; Bortezomib; Camptothecin; Deoxycytidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Forecasting; Gemcitabine; Green Fluorescent Proteins; Humans; Image Enhancement; Irinotecan; Luminescent Proteins; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Pyrazines; Red Fluorescent Protein; Technology, Pharmaceutical; Treatment Outcome

2005
Irinotecan changes gene expression in the small intestine of the rat with breast cancer.
    Cancer chemotherapy and pharmacology, 2007, Volume: 59, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Caspase 1; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Irinotecan; Jejunum; Mammary Neoplasms, Experimental; Mitogen-Activated Protein Kinase Kinases; Mucositis; Oligonucleotide Array Sequence Analysis; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation

2007
Addition of a topoisomerase I inhibitor to trimodality therapy [cis-diamminedichloroplatinum(II)/heat/radiation] in a murine tumor.
    Journal of cancer research and clinical oncology, 1993, Volume: 119, Issue:11

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Camptothecin; Cell Hypoxia; Cell Survival; Cisplatin; Combined Modality Therapy; Female; Fibrosarcoma; Hydrogen-Ion Concentration; Hyperthermia, Induced; Mammary Neoplasms, Experimental; Mice; Topoisomerase I Inhibitors; Topotecan; Tumor Cells, Cultured

1993
Radiation enhancement by 9-aminocamptothecin. Evidence for improved therapeutic ratio with a multiple dose schedule.
    Annals of the New York Academy of Sciences, 1996, Dec-13, Volume: 803

    Topics: Animals; Camptothecin; Combined Modality Therapy; Drug Administration Schedule; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H

1996
Influence of low pH on cytotoxicity of paclitaxel, mitoxantrone and topotecan.
    British journal of cancer, 1997, Volume: 75, Issue:8

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Cycle; Cell Survival; DNA, Neoplasm; Female; Humans; Hydrogen-Ion Concentration; Mammary Neoplasms, Experimental; Mice; Mitoxantrone; Paclitaxel; Topotecan; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1997
Potentiation of murine MCa-4 carcinoma radioresponse by 9-amino-20(S)-camptothecin.
    Cancer research, 1997, May-15, Volume: 57, Issue:10

    Topics: Animals; Antineoplastic Agents; Camptothecin; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Radiation-Sensitizing Agents

1997
Overcoming CPT-11 resistance by using a biscoclaurine alkaloid, cepharanthine, to modulate plasma trans-membrane potential.
    International journal of cancer, 1997, Jul-17, Volume: 72, Issue:2

    Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Benzylisoquinolines; Biological Transport; Camptothecin; Cell Membrane; Drug Interactions; Drug Resistance, Neoplasm; Drug Therapy, Combination; Female; Irinotecan; Mammary Neoplasms, Experimental; Mice; Tumor Cells, Cultured

1997
Sequence effect of irinotecan (CPT-11) and topoisomerase II inhibitors in vivo.
    Cancer chemotherapy and pharmacology, 1998, Volume: 42, Issue:4

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Death; DNA, Neoplasm; Doxorubicin; Drug Interactions; Etoposide; Female; Irinotecan; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; RNA, Messenger; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1998
Local delivery of chemotherapy prolongs survival in experimental brain metastases from breast carcinoma.
    Neurosurgery, 1998, Volume: 43, Issue:5

    Topics: Animals; Antineoplastic Agents; Brain; Brain Neoplasms; Camptothecin; Carboplatin; Carmustine; Combined Modality Therapy; Cranial Irradiation; Delayed-Action Preparations; Drug Implants; Female; Injections, Intralesional; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Polymers; Tumor Cells, Cultured

1998
Cellular pharmacology of the combination of the DNA topoisomerase I inhibitor SN-38 and the diaminocyclohexane platinum derivative oxaliplatin.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:5

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Cell Cycle; Colonic Neoplasms; Cross-Linking Reagents; DNA Adducts; DNA Damage; DNA, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Mammary Neoplasms, Experimental; Nucleic Acid Synthesis Inhibitors; Organoplatinum Compounds; Oxaliplatin; RNA, Neoplasm; Topoisomerase I Inhibitors; Tumor Cells, Cultured

1999
9-Nitrocamptothecin liposome aerosol treatment of human cancer subcutaneous xenografts and pulmonary cancer metastases in mice.
    Annals of the New York Academy of Sciences, 2000, Volume: 922

    Topics: Aerosols; Animals; Antineoplastic Agents; Bone Neoplasms; Camptothecin; Colonic Neoplasms; Drug Carriers; Female; Humans; Liposomes; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; Microscopy, Electron; Osteosarcoma; Particle Size; Phosphatidylcholines; Xenograft Model Antitumor Assays

2000
Modified lactone/carboxylate salt equilibria in vivo by liposomal delivery of 9-nitro-camptothecin.
    Annals of the New York Academy of Sciences, 2000, Volume: 922

    Topics: Animals; Antineoplastic Agents; Camptothecin; Carboxylic Acids; Chemistry, Pharmaceutical; Colonic Neoplasms; Delayed-Action Preparations; Drug Stability; Humans; Lactones; Liposomes; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Rats; Rats, Sprague-Dawley; Solubility; Tissue Distribution; Xenograft Model Antitumor Assays

2000
Camptothecin dose, schedule, and timing of administration for clinical radiation sensitization.
    Annals of the New York Academy of Sciences, 2000, Volume: 922

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Division; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Administration Schedule; Mammary Neoplasms, Experimental; Mice; Radiation-Sensitizing Agents

2000
Role of DNA topoisomerase I in the transcription of supercoiled rRNA gene.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:10

    Topics: Adenocarcinoma; Animals; Camptothecin; DNA Topoisomerases, Type I; DNA, Superhelical; Genes; Mammary Neoplasms, Experimental; Rats; RNA Polymerase I; RNA, Ribosomal; Transcription Factors; Transcription, Genetic

1987