camptothecin has been researched along with Experimental Leukemia in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (38.89) | 18.7374 |
| 1990's | 11 (61.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adamovics, JA; Hutchinson, CR | 1 |
| Creasey, WA; Gil, D; Richards, M; Tsou, KC | 1 |
| Fujimori, A; Harker, WG; Kapoor, R; Pommier, Y; Slade, DL | 1 |
| Bertrand, R; Jenkins, J; Pommier, Y; Solary, E | 1 |
| DeJesus, A; Early, J; Giovanella, BC; Mendoza, J; Pantazis, P; Shaw, M | 1 |
| Aboud, M; Aflalo, E; Benharroch, D; Chechelnitsky, G; Priel, E; Segal, S | 1 |
| Early, JA; Giovanella, BC; Kozielski, AJ; Mendoza, JT; Natelson, EA; Pantazis, P | 1 |
| Pantazis, P | 1 |
| Bissery, MC; Chabot, GG; Lavelle, F; Vrignaud, P | 1 |
| Beran, M; Jeha, S; Kantarjian, H; O'Brien, S; Vitek, L | 1 |
| Bailly, C; Bigg, DC; Camara, J; Dassonneville, L; Demarquay, D; Kasprzyk, PG; Kiss, R; Lavergne, O; Lesueur-Ginot, L | 1 |
| Adamson, RH; Mead, JA; Sieber, SM | 1 |
| Taylor, H; Wall, ME; Wani, MC | 1 |
| Andoh, T; Okada, K | 1 |
| Chou, S; Kaneko, M; Nakamura, Y; Nakaya, K | 1 |
| Bartus, JO; Drake, FH; Hertzberg, RP; Hofmann, GA; Johnson, RK; Mattern, MR; Mirabelli, CK; Mong, SM | 1 |
| Eng, WK; Johnson, RK; Mattern, MR; McCabe, FL; Tan, KB | 1 |
| Bosmann, HB | 1 |
3 review(s) available for camptothecin and Experimental Leukemia
| Article | Year |
|---|---|
The water-insoluble camptothecin analogues: promising drugs for the effective treatment of haematological malignancies.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biotransformation; Camptothecin; Cell Differentiation; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Humans; Leukemia; Leukemia, Experimental; Lymphoma; Mice; Phosphorylation; Solubility; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1995 |
Pharmacology of antitumor agents from higher plants.
Topics: Animals; Antineoplastic Agents, Phytogenic; Aporphines; Camptothecin; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Etoposide; Humans; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Maytansine; Melanoma; Naphthoquinones; Nasopharyngeal Neoplasms; Neoplasms; Neoplasms, Experimental; Phenanthrenes; Structure-Activity Relationship; Teniposide; Vinblastine; Vincristine | 1976 |
[Mechanisms of acquired resistance to DNA topoisomerase I inhibitors].
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Doxorubicin; Drug Resistance; Humans; Irinotecan; Leukemia, Experimental; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1991 |
15 other study(ies) available for camptothecin and Experimental Leukemia
| Article | Year |
|---|---|
Prodrug analogues of the antitumor alkaloid camptothecin.
Topics: Animals; Antineoplastic Agents; Camptothecin; Leukemia L1210; Leukemia, Experimental; Lung Neoplasms; Melanoma; Mice; Neoplasms, Experimental | 1979 |
Action of (S)-10-hydroxycamptothecin on P388 leukemia and distribution of the drug in mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; DNA, Neoplasm; Flow Cytometry; Leukemia P388; Leukemia, Experimental; Mice; Tissue Distribution | 1983 |
Altered topoisomerase I expression in two subclones of human CEM leukemia selected for resistance to camptothecin.
Topics: Acute Disease; Base Sequence; Camptothecin; Catalysis; DNA Damage; DNA Topoisomerases, Type I; DNA, Neoplasm; Drug Resistance; Humans; Leukemia, Experimental; Leukemia, T-Cell; Molecular Sequence Data; Neoplasm Proteins; RNA, Messenger; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1995 |
Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminoquinolines; Aphidicolin; Apoptosis; Benzamides; Calcium; Calmodulin; Camptothecin; Cell Cycle; Chromatin; Cyclosporine; DNA; Egtazic Acid; Ethers, Cyclic; Humans; Isoquinolines; Leukemia, Experimental; Leukemia, Promyelocytic, Acute; Microscopy, Electron; Naphthalenes; Okadaic Acid; Phosphoprotein Phosphatases; Piperazines; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Polycyclic Compounds; Protein Kinase C; Spermine; Staurosporine; Teniposide; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Zinc | 1993 |
Development of resistance to 9-nitro-camptothecin by human leukemia U-937 cells in vitro correlates with altered sensitivities to several anticancer drugs.
Topics: Antineoplastic Agents; Camptothecin; Cell Cycle; Cell Division; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Leukemia, Experimental; Microscopy; Tumor Cells, Cultured | 1994 |
Inhibition of retrovirus-induced disease in mice by camptothecin.
Topics: 3T3 Cells; Acute Disease; Animals; Animals, Newborn; Camptothecin; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Lymphoma; Mice; Mice, Inbred BALB C; Moloney murine leukemia virus; Neoplasms, Experimental; Retroviridae Infections; Spleen; Spleen Focus-Forming Viruses; Virus Replication | 1993 |
9-Nitro-camptothecin delays growth of U-937 leukemia tumors in nude mice and is cytotoxic or cytostatic for human myelomonocytic leukemia lines in vitro.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Cycle; Cell Death; DNA, Neoplasm; Growth Inhibitors; Humans; In Vitro Techniques; Leukemia, Experimental; Leukemia, Myeloid; Mice; Mice, Nude; Neoplasm Transplantation; Tumor Cells, Cultured | 1993 |
Experimental antitumor activity and pharmacokinetics of the camptothecin analog irinotecan (CPT-11) in mice.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Docetaxel; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Irinotecan; Leukemia, Experimental; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Paclitaxel; Sensitivity and Specificity; Taxoids; Vincristine | 1996 |
Activity of oral and intravenous 9-aminocamptothecin in SCID mice engrafted with human leukemia.
Topics: Acute Disease; Administration, Oral; Animals; Camptothecin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; HLA-DQ alpha-Chains; HLA-DQ Antigens; Humans; Injections, Intravenous; Leukemia, Experimental; Leukemia, Myeloid; Mice; Mice, SCID; Neoplasm Transplantation; Survival Rate | 1998 |
Homocamptothecin, an E-ring modified camptothecin with enhanced lactone stability, retains topoisomerase I-targeted activity and antitumor properties.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Division; Disease Models, Animal; DNA; Drug Screening Assays, Antitumor; Drug Stability; Enzyme Inhibitors; HT29 Cells; Humans; K562 Cells; Lactones; Leukemia L1210; Leukemia, Experimental; Neoplasm Transplantation; Topoisomerase I Inhibitors; Transplantation, Heterologous; Tumor Cells, Cultured | 1999 |
Isolation and chemical characterization of antitumor agents from plants.
Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carubicin; Chemical Fractionation; Chemical Phenomena; Chemistry; Chromatography; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Countercurrent Distribution; Humans; Leukemia L1210; Leukemia, Experimental; Longevity; Mice; Neoplasms; Plant Extracts; Spectrum Analysis | 1976 |
Induction of differentiation of human and mouse myeloid leukemia cells by camptothecin.
Topics: Animals; Biomarkers; Camptothecin; Cell Differentiation; Cell Line; Humans; Kinetics; Leukemia; Leukemia, Experimental; Mice; Phagocytosis; Receptors, Fc; Time Factors; Tumor Cells, Cultured | 1990 |
In vitro and intracellular inhibition of topoisomerase II by the antitumor agent merbarone.
Topics: Amsacrine; Animals; Antineoplastic Agents; Camptothecin; DNA; DNA Damage; Leukemia, Experimental; Mice; Teniposide; Thiobarbiturates; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 1989 |
Nonproductive rearrangement of DNA topoisomerase I and II genes: correlation with resistance to topoisomerase inhibitors.
Topics: Alleles; Amsacrine; Animals; Camptothecin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Resistance; Gene Expression Regulation; Gene Rearrangement; Leukemia P388; Leukemia, Experimental; Methylation; Methyltransferases; Mice; RNA, Messenger; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transcription, Genetic | 1989 |
Antineoplastic drug activity in the mitotic cycle--effects of six agents on macromolecular synthesis in synchronous mammalian leukemic cells.
Topics: Animals; Antineoplastic Agents; Asparaginase; Azaserine; Camptothecin; Culture Media; DNA, Neoplasm; Ethidium; Fucose; Glucosamine; Glycoproteins; Hydroxyurea; Leucine; Leukemia, Experimental; Mice; Mitosis; Neoplasm Proteins; RNA, Neoplasm; Thymidine; Time Factors; Tritium; Uridine | 1972 |