Page last updated: 2024-08-22

camptothecin and Experimental Hepatoma

camptothecin has been researched along with Experimental Hepatoma in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19909 (20.93)18.7374
1990's8 (18.60)18.2507
2000's3 (6.98)29.6817
2010's20 (46.51)24.3611
2020's3 (6.98)2.80

Authors

AuthorsStudies
Cai, B; Huang, M; Jiang, J; Li, Z; Luo, M; Wang, L; Wu, L1
Liang, GB; Ma, XL; Su, D; Wei, JH; Xin, M; Yang, CH; Zhang, Y1
Cai, K; Li, B; Li, K; Lin, C; Liu, G; Lu, L; Luo, Z; Xia, Z1
Huang, S; Li, M; Nie, X; Ren, D; Wang, Y; Wu, X; Yu, X1
Chen, M; Chen, Z; Li, X; Liu, W; Wang, T; Xie, S; Zhao, L1
He, W; Jiang, Y; Li, Q; Li, Z; Luan, Y; Zhang, D1
Du, FF; Hu, ZY; Li, C; Li, XX; Niu, W; Sun, Y; Wang, FQ; Xu, F; Yang, JL1
Delaunay, F; Dulong, S; Dumitru, M; Filipski, E; Guettier, C; Lévi, F; Li, XM; Mohammad-Djafari, A; Mteyrek, A; Scaglione, F; Siffroi-Fernandez, S1
Adams, R; Becker, M; Bhargava, A; Ellinghaus, P; Hoffmann, J; Kahmann, N; Müller, T; Rosenthal, A; Schmieder, R; Scholz, A; Thierauch, KH; Wilhelm, SM; Zopf, D1
Hu, HH; Song, HX1
Gilbert, CW; Hukuoka, Y; Kichikawa, K; Masada, T; Nishiofuku, H; Obayashi, C; Sato, T; Takano, M; Tanaka, T1
Hayashi, A; Higashi, Y; Hori, Y; Kishimoto, K; Maeda, N; Morii, E; Ohashi, F; Osuga, K; Tanaka, K; Tomiyama, N1
Ghegediban, SH; Laurent, A; Maeda, N; Namur, J; Osuga, K; Paci, A; Pascale, F; Reb, P; Seck, A; Sterba, M; Verret, V; Wassef, M1
Caine, M; Dreher, MR; Dunn, A; Fowers, KD; Grey, D; Hall, B; Johnson, CG; Lewis, AL; O'Byrne, V; Sharma, KV; Tang, Y; Wood, BJ1
Fukuoka, Y; Kichikawa, K; Masada, T; Matsushima, S; Nishiofuku, H; Ohbayashi, C; Sato, T; Sho, M; Takano, M; Tanaka, T; Tatsumoto, S; Yamato, I; Yasuda, S1
Li, J; Oupický, D; Ping, Q; Qiao, H; Su, Z; Sun, M; Xie, Y; Zhang, C1
Gu, J; Han, HB; Hu, MH; Li, JY; Wang, Y; Xie, Y; Xing, BC; Xu, XL; Xu, ZL; Zhang, ZQ; Zhao, W1
Gong, T; Liu, J; Ren, K; Shi, SJ; Sun, X; Wei, W; Zhang, XN; Zhang, ZR; Zhao, D1
Kenmotsu, H; Kinoshita, T; Koga, Y; Kuroda, J; Matsumura, Y; Ohkohchi, N; Takahashi, A; Yasunaga, M1
Feng, G; Liang, B; Liang, H; Qian, J; Wang, Y; Zhao, H; Zheng, C1
Auperin, A; Bize, P; de Baere, T; Denys, A; Deschamps, F; Drouard-Troalen, L; Paci, A; Pascale, F; Rao, PP; Seck, A; Teriitheau, C1
Fu, H; Grieves, JL; La Perle, KM; McCarty, DM; Rosas, LE; Zaraspe, K1
Jia, G; Li, X; Luo, X; Song, H; Xu, G; Yan, S; Yang, S1
Evans, JF; Kargman, S; Kelly, CR; Kwong, E; Lam, EC; Luk, P; Wolfe, MM; Yao, M; Zheng, Y1
Aoyagi, Y; Enomoto, T; Nakajima, M; Noguchi, M; Oda, T; Ohkohchi, N; Satake, M; Sugiura, S1
Ling, YH; Xu, B; Yu, WJ2
Han, JX; Shen, ZM; Xu, B; Yang, JL1
Lo, KW; Miller, EE; Tsou, KC; Xu, B1
Ling, YH; Xu, B2
Chan, J; Roffler, SR; Yeh, MY1
Brumfield, A; Dookeran, KA; Rubin, JT1
Fidler, IJ; Killion, JJ; Kumar, R; Kuniyasu, H; Shinohara, H1
Hashimoto, A; Matsuura, T; Murakami, K; Saiki, I; Sakukawa, R; Sano, M; Yamada, Y; Yonekura, K1
Qing, C; Xu, B; Zhang, XW1
Bucci, F; Capocasa, F; Carenini, N; Carminati, P; De Cesare, M; Merlini, L; Pace, S; Penco, S; Perego, P; Pisano, C; Pratesi, G; Tinelli, S; Vesci, L; Zunino, F1
Shu, RS; Wang, ZW; Xu, B1
Liu, J; Xu, B; Yang, SL1
Wu, XJ2
Ling, YH; Xu, B; Zhao, CS1

Other Studies

43 other study(ies) available for camptothecin and Experimental Hepatoma

ArticleYear
Design, synthesis, biological evaluation and structure-activity relationship of sophoridine derivatives bearing pyrrole or indole scaffold as potential antitumor agents.
    European journal of medicinal chemistry, 2018, Sep-05, Volume: 157

    Topics: Alkaloids; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Indoles; Liver Neoplasms, Experimental; Matrines; Mice; Molecular Docking Simulation; Molecular Structure; Pyrroles; Quinolizines; Structure-Activity Relationship

2018
Design, synthesis and biological evaluation of 3-nitro-1,8-naphthalimides as potential antitumor agents.
    Bioorganic & medicinal chemistry letters, 2020, 04-15, Volume: 30, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Liver Neoplasms, Experimental; Mice; Molecular Structure; Naphthalimides; Structure-Activity Relationship

2020
Redox-responsive amphiphilic camptothecin prodrug nanoparticles for targeted liver tumor therapy.
    Journal of materials chemistry. B, 2020, 05-06, Volume: 8, Issue:17

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Proliferation; Cell Survival; Cells, Cultured; Drug Screening Assays, Antitumor; Female; Hep G2 Cells; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Nanoparticles; Optical Imaging; Oxidation-Reduction; Particle Size; Prodrugs; Surface Properties; Surface-Active Agents

2020
Glycyrrhetinic Acid and TAT Peptide Modified Dual-functional Liposomes for Treatment of Hepatocellular Cancer.
    Current topics in medicinal chemistry, 2020, Volume: 20, Issue:27

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Glycyrrhetinic Acid; Hep G2 Cells; Humans; Liposomes; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Nanoparticles; Particle Size; Peptide Fragments; Surface Properties; tat Gene Products, Human Immunodeficiency Virus; Tumor Cells, Cultured

2020
Acid-Labile Degradation of Injectable Fiber Fragments to Release Bioreducible Micelles for Targeted Cancer Therapy.
    Biomacromolecules, 2018, 04-09, Volume: 19, Issue:4

    Topics: Animals; Apoptosis; Camptothecin; Cell Aggregation; Cell Proliferation; Hep G2 Cells; Humans; Hyaluronic Acid; Liver Neoplasms, Experimental; Mice; Micelles; Polyesters; Stilbenes

2018
A versatile strategy to create an active tumor-targeted chemo-photothermal therapy nanoplatform: A case of an IR-780 derivative co-assembled with camptothecin prodrug.
    Acta biomaterialia, 2019, 01-15, Volume: 84

    Topics: Animals; Camptothecin; Drug Delivery Systems; Hep G2 Cells; Humans; Hyperthermia, Induced; Indoles; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Phototherapy; Prodrugs

2019
Pharmacokinetic evaluation of the anticancer prodrug simmitecan in different experimental animals.
    Acta pharmacologica Sinica, 2013, Volume: 34, Issue:11

    Topics: Animals; Antineoplastic Agents; Camptothecin; Carboxylesterase; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Half-Life; Humans; Injections, Intravenous; Liver Neoplasms, Experimental; Male; Mice; Mice, Nude; Microsomes, Liver; Prodrugs; Rats; Rats, Sprague-Dawley; Species Specificity; Tissue Distribution; Xenograft Model Antitumor Assays

2013
A circadian clock transcription model for the personalization of cancer chronotherapy.
    Cancer research, 2013, Dec-15, Volume: 73, Issue:24

    Topics: Animals; ARNTL Transcription Factors; Camptothecin; Chronotherapy; Circadian Clocks; Colonic Neoplasms; Female; Gene Expression Regulation, Neoplastic; Irinotecan; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Models, Biological; Nuclear Receptor Subfamily 1, Group D, Member 1; Period Circadian Proteins; Precision Medicine; RNA, Messenger; Topoisomerase I Inhibitors

2013
Regorafenib (BAY 73-4506): antitumor and antimetastatic activities in preclinical models of colorectal cancer.
    International journal of cancer, 2014, Sep-15, Volume: 135, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Growth Processes; Cell Line, Tumor; Colorectal Neoplasms; Drug Resistance, Neoplasm; Female; Humans; Irinotecan; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Phenylurea Compounds; Pyridines; Random Allocation; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factor Receptor-3; Xenograft Model Antitumor Assays

2014
[Efficacy of treatment with siRNA targeting Bcl-2 in combination with HCPT against transplanted H₂₂ hepatoma in mice].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2013, Volume: 35, Issue:12

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Cycle; Drug Synergism; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Proto-Oncogene Proteins c-bcl-2; Random Allocation; RNA, Messenger; RNA, Small Interfering; Transfection; Tumor Burden

2013
Pharmacokinetics and antitumor efficacy of chemoembolization using 40 µm irinotecan-loaded microspheres in a rabbit liver tumor model.
    Journal of vascular and interventional radiology : JVIR, 2014, Volume: 25, Issue:7

    Topics: Alkaline Phosphatase; Animals; Antineoplastic Agents, Phytogenic; Aspartate Aminotransferases; Camptothecin; Chemistry, Pharmaceutical; Chemoembolization, Therapeutic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Monitoring; Irinotecan; Liver Neoplasms, Experimental; Microspheres; Necrosis; Particle Size; Rabbits

2014
In vivo evaluation of irinotecan-loaded QuadraSphere microspheres for use in chemoembolization of VX2 liver tumors.
    Journal of vascular and interventional radiology : JVIR, 2014, Volume: 25, Issue:11

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chemoembolization, Therapeutic; Disease Models, Animal; Female; Irinotecan; Liver Neoplasms, Experimental; Microspheres; Rabbits; Tomography, X-Ray Computed; Treatment Outcome

2014
Safety and efficacy compared between irinotecan-loaded microspheres HepaSphere and DC bead in a model of VX2 liver metastases in the rabbit.
    Journal of vascular and interventional radiology : JVIR, 2015, Volume: 26, Issue:7

    Topics: Activation, Metabolic; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Chemoembolization, Therapeutic; Drug Carriers; Gene Expression Regulation, Neoplastic; Hepatic Artery; Injections, Intra-Arterial; Irinotecan; Liver Neoplasms, Experimental; Male; Microspheres; Necrosis; Particle Size; Rabbits; Tissue Distribution

2015
DC BeadM1™: towards an optimal transcatheter hepatic tumour therapy.
    Journal of materials science. Materials in medicine, 2016, Volume: 27, Issue:1

    Topics: Animals; Antineoplastic Agents; Camptothecin; Catheters; Doxorubicin; Drug Carriers; Irinotecan; Liver Neoplasms, Experimental; Rabbits; X-Ray Microtomography

2016
Intraarterial Therapy Using Micellar Nanoparticles Incorporating SN-38 in a Rabbit Liver Tumor Model.
    Journal of vascular and interventional radiology : JVIR, 2017, Volume: 28, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Area Under Curve; Camptothecin; Drug Carriers; Drug Compounding; Female; Femoral Vein; Hepatic Artery; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Liver Neoplasms, Experimental; Micelles; Nanoparticles; Necrosis; Rabbits; Tissue Distribution

2017
Arginine-Modified Nanostructured Lipid Carriers with Charge-Reversal and pH-Sensitive Membranolytic Properties for Anticancer Drug Delivery.
    Advanced healthcare materials, 2017, Volume: 6, Issue:8

    Topics: Animals; Antineoplastic Agents; Arginine; Camptothecin; Chitosan; Drug Carriers; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Liver Neoplasms, Experimental; Male; Mice; Nanostructures; Rats; Rats, Sprague-Dawley; Xenograft Model Antitumor Assays

2017
The properties of tumor-initiating cells from a hepatocellular carcinoma patient's primary and recurrent tumor.
    Carcinogenesis, 2010, Volume: 31, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blotting, Western; Camptothecin; Carcinoma, Hepatocellular; Cell Adhesion; Cisplatin; Comparative Genomic Hybridization; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Gene Expression Profiling; Humans; Liver Neoplasms, Experimental; Male; Mice; Mice, SCID; Middle Aged; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Oligonucleotide Array Sequence Analysis; Paclitaxel; Poly(ADP-ribose) Polymerases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2010
Lipid nanoparticles loaded with 10-hydroxycamptothecin-phospholipid complex developed for the treatment of hepatoma in clinical application.
    Journal of drug targeting, 2010, Volume: 18, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Female; Hep G2 Cells; Humans; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Particle Size; Phospholipids; Tissue Distribution

2010
Detailed distribution of NK012, an SN-38-incorporating micelle, in the liver and its potent antitumor effects in mice bearing liver metastases.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Oct-01, Volume: 16, Issue:19

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Proliferation; Chromatography, High Pressure Liquid; Colonic Neoplasms; Disease Models, Animal; Humans; Irinotecan; Kaplan-Meier Estimate; Liver; Liver Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2010
Hepatocellular necrosis, apoptosis, and proliferation after transcatheter arterial embolization or chemoembolization in a standardized rabbit model.
    Journal of vascular and interventional radiology : JVIR, 2011, Volume: 22, Issue:11

    Topics: Alanine Transaminase; Angiography, Digital Subtraction; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Aspartate Aminotransferases; Camptothecin; Carcinoma, Hepatocellular; Cell Proliferation; Chemoembolization, Therapeutic; Embolization, Therapeutic; Hepatic Artery; In Situ Nick-End Labeling; Iodized Oil; Ki-67 Antigen; Liver Function Tests; Liver Neoplasms, Experimental; Liver Regeneration; Magnetic Resonance Imaging; Necrosis; Polyvinyl Alcohol; Rabbits; Time Factors; Tomography, X-Ray Computed; Tumor Necrosis Factor-alpha

2011
Irinotecan loaded in eluting beads: preclinical assessment in a rabbit VX2 liver tumor model.
    Cardiovascular and interventional radiology, 2012, Volume: 35, Issue:6

    Topics: Alanine Transaminase; Animals; Antineoplastic Agents, Phytogenic; Aspartate Aminotransferases; Bilirubin; Camptothecin; Chemoembolization, Therapeutic; Drug Delivery Systems; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Liver Neoplasms, Experimental; Rabbits; Statistics, Nonparametric

2012
Patterns of scAAV vector insertion associated with oncogenic events in a mouse model for genotoxicity.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2012, Volume: 20, Issue:11

    Topics: Animals; Base Sequence; Camptothecin; Carcinoma, Hepatocellular; Dependovirus; DNA Damage; Female; Fibroblast Growth Factor 10; Fibroblast Growth Factor 3; Genetic Vectors; Genome, Viral; Hepatectomy; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C3H; Mice, SCID; Molecular Sequence Data; Mutagenesis, Insertional; Proto-Oncogene Proteins p21(ras); Proto-Oncogenes; SOS1 Protein; Transcriptional Activation; Virus Integration

2012
Promoted antitumor activities of acid-labile electrospun fibers loaded with hydroxycamptothecin via intratumoral implantation.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2012, Volume: 82, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzaldehydes; Camptothecin; Carcinoma, Hepatocellular; Electrochemistry; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Lactates; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Molecular Weight; Polyethylene Glycols; Survival Rate; Tumor Microenvironment

2012
Inhibition of cyclooxygenase-2 by rofecoxib attenuates the growth and metastatic potential of colorectal carcinoma in mice.
    Cancer research, 2003, Feb-01, Volume: 63, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; beta Catenin; Camptothecin; Cell Division; Colorectal Neoplasms; Cyclin D1; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytoskeletal Proteins; Dinoprostone; Drug Synergism; Endothelial Growth Factors; Fluorouracil; Intercellular Signaling Peptides and Proteins; Interleukin-10; Interleukin-12; Irinotecan; Isoenzymes; Lactones; Liver Neoplasms, Experimental; Lymphokines; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Membrane Proteins; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Prostaglandin-Endoperoxide Synthases; Sulfones; Trans-Activators; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2003
Consistent liver metastases in a rat model by portal injection of microencapsulated cancer cells.
    Cancer research, 2006, Dec-01, Volume: 66, Issue:23

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Disease Models, Animal; Gemcitabine; Humans; Injections, Intravenous; Irinotecan; Liver Neoplasms, Experimental; Mice; Mice, Nude; Microspheres; Neoplasm Transplantation; Pancreatic Neoplasms; Portal Vein; Rats; Rats, Nude; Transplantation, Heterologous

2006
[Effect of 10-hydroxycamptothecin on nuclear RNA polymerase activity in hepatoma cells in mice].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1984, Volume: 5, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Nucleus; DNA-Directed RNA Polymerases; Liver Neoplasms, Experimental; Mice

1984
[Effects of 10-hydroxycamptothecin on cAMP and cGMP levels in hepatoma and liver tissue of mice (author's transl)].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1981, Volume: 2, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cyclic AMP; Cyclic GMP; DNA, Neoplasm; Liver; Liver Neoplasms, Experimental; Mice; Mice, Inbred ICR

1981
[Effect of 10-hydroxycamptothecin on adenylate cyclase activity in murine hepatoma cells].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1982, Volume: 3, Issue:4

    Topics: Adenylyl Cyclases; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cyclic AMP; Dopamine; Liver Neoplasms, Experimental; Mice

1982
Anti-tumor effect of (S)-10-hydroxycamptothecin on mouse hepatoma BW7756 and its possible mode of action.
    Anticancer research, 1981, Volume: 1, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Division; Flow Cytometry; Liver Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasm Transplantation

1981
Inhibition of phosphorylation of histone H1 and H3 induced by 10-hydroxycamptothecin, DNA topoisomerase I inhibitor, in murine ascites hepatoma cells.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, Volume: 14, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; DNA, Neoplasm; Histones; Liver Neoplasms, Experimental; Mice; Phosphorylation; Topoisomerase I Inhibitors; Tumor Cells, Cultured

1993
Potentiation of radioimmunotherapy by inhibition of topoisomerase I.
    Cancer research, 1994, Mar-01, Volume: 54, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Camptothecin; Combined Modality Therapy; Female; Gamma Rays; Liver Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Radioimmunotherapy; Rats; Rats, Sprague-Dawley; Topoisomerase I Inhibitors

1994
A comparison of locoregional depot and systemic preparations of 9-aminocamptothecin for treatment of liver metastases in a rat tumor model: superior antitumor activity of sustained-release preparation.
    Annals of surgical oncology, 1997, Volume: 4, Issue:4

    Topics: Animals; Antineoplastic Agents; Camptothecin; Delayed-Action Preparations; Disease Models, Animal; Drug Delivery Systems; Ethiodized Oil; Liver Neoplasms, Experimental; Rats; Rats, Inbred F344

1997
Prevention of intestinal toxic effects and intensification of irinotecan's therapeutic efficacy against murine colon cancer liver metastases by oral administration of the lipopeptide JBT 3002.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:9

    Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Administration Schedule; Drug Synergism; Intestinal Diseases; Irinotecan; Lipopeptides; Lipoproteins; Liver Neoplasms, Experimental; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C

1998
4-[3,5-Bis(trimethylsilyl)benzamido] benzoic acid (TAC-101) inhibits the intrahepatic spread of hepatocellular carcinoma and prolongs the life-span of tumor-bearing animals.
    Clinical & experimental metastasis, 1998, Volume: 16, Issue:7

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Benzoates; Body Weight; Camptothecin; Carcinoma, Hepatocellular; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Mice, Nude; Molecular Structure; Neoplasm Invasiveness; Proto-Oncogene Proteins c-met; Receptors, Retinoic Acid; Reverse Transcriptase Polymerase Chain Reaction; Specific Pathogen-Free Organisms; Survival Rate; Trimethylsilyl Compounds; Tumor Cells, Cultured

1998
Apoptosis induction and cell cycle perturbation in human hepatoma hep G2 cells by 10-hydroxycamptothecin.
    Anti-cancer drugs, 1999, Volume: 10, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Cycle; Cell Division; Cell Nucleus; Cell Survival; DNA Fragmentation; DNA, Neoplasm; Electrophoresis, Agar Gel; Humans; Kinetics; Liver Neoplasms, Experimental; Microscopy, Fluorescence; Tumor Cells, Cultured

1999
Potent antitumor activity and improved pharmacological profile of ST1481, a novel 7-substituted camptothecin.
    Cancer research, 2001, Oct-01, Volume: 61, Issue:19

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Non-Small-Cell Lung; Doxorubicin; Drug Administration Schedule; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2001
[Influence of sodium camptothecin on the concomitant tumor immunity in mice (author's transl)].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1979, Volume: 14, Issue:1

    Topics: Animals; Camptothecin; Liver Neoplasms, Experimental; Mice; Neoplasm Transplantation; Sarcoma, Experimental; Transplantation, Isogeneic

1979
[The influence of 10-hydroxycamptothecin on the ultrastructure of ascitic hepatoma cells in mice (author's transl)].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1979, Volume: 1, Issue:3

    Topics: Animals; Camptothecin; Carcinoma, Ehrlich Tumor; Liver Neoplasms, Experimental; Mice

1979
Effects of lycobetaine on chromatin structure and activity of murine hepatoma cells.
    Science in China. Series B, Chemistry, life sciences & earth sciences, 1990, Volume: 33, Issue:12

    Topics: Alkaloids; Amaryllidaceae Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Chromatin; Dactinomycin; DNA Damage; DNA, Neoplasm; Harringtonines; Homoharringtonine; Indolizines; Liver Neoplasms, Experimental; Mice; Oncogenes; Time Factors; Tumor Cells, Cultured

1990
[An experimental study of the basic properties of drug microspheres and target treatment of rats with liver tumor].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1990, Volume: 28, Issue:4

    Topics: Animals; Camptothecin; Delayed-Action Preparations; Embolization, Therapeutic; Female; Infusions, Intra-Arterial; Liver Neoplasms, Experimental; Male; Microspheres; Rats; Rats, Inbred Strains

1990
[The effect of drug-microsphere embolization of hepatic artery on normal liver and experimental hepatic tumor in rats].
    Zhonghua fang she xue za zhi Chinese journal of radiology, 1989, Volume: 23, Issue:6

    Topics: Animals; Camptothecin; Capsules; Embolization, Therapeutic; Female; Hepatic Artery; Liver Neoplasms, Experimental; Male; Microspheres; Radiography; Rats; Rats, Inbred Strains

1989
[Effects of 10-hydroxycamptothecin on chromatin protein synthesis in murine hepatoma cells].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1986, Volume: 7, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chromatin; Chromosomal Proteins, Non-Histone; Histones; Liver Neoplasms, Experimental; Mice

1986
The effect of hydroxycamptothecin in the activity of RNA and DNA polymerases prepared from murine hepatoma cells.
    The American journal of Chinese medicine, 1985, Volume: 13, Issue:1-4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Nucleus; DNA Polymerase I; DNA Polymerase II; DNA Replication; DNA-Directed RNA Polymerases; In Vitro Techniques; Liver Neoplasms, Experimental; Mice; Nucleic Acid Synthesis Inhibitors

1985