Page last updated: 2024-08-22

camptothecin and Cancer of Skin

camptothecin has been researched along with Cancer of Skin in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (12.50)18.2507
2000's11 (34.38)29.6817
2010's11 (34.38)24.3611
2020's6 (18.75)2.80

Authors

AuthorsStudies
Cao, S; Chen, X; Li, J; Li, Y; Lian, C; Peng, C; Su, J; Tao, J; Wu, L; Zeng, W; Zhao, S; Zhou, J1
Li, S; Yu, Y; Zhang, F; Zhang, Q1
Cheng, Q; Liao, L; Pei, F; Ye, S; Zhu, G1
Girardi, M; Griff, S; Hu, JK; Lee, AK; Lewis, JM; Moscato, ZM; Qureshi, M; Saltzman, WM; Suh, HW; Yaqoob, S; Yin, ES1
Bakre, S; Filippov, SK; Krishnan, V; Lujano, O; Mandinova, A; Mitragotri, S; Peng, K; Prakash, S; Pusuluri, A; Sarode, A; Sell, BR; Todorova, K; Tsai, KY; Vogus, D; Zhao, Z1
Hashimoto, H; Ito, T; Kaku-Ito, Y; Murata, M; Oda, Y; Tanaka, Y; Tanegashima, K1
Boku, N; Fujiki, T; Fujino, K; Gemma, A; Kakihata, K; Masatani, S; Morita, S; Shiozawa, T; Tadokoro, J1
Hirano, S; Ikura, Y; Ishimura, M; Iwai, Y; Kadota, C; Kadota, T; Kitami, M; Nakajima, E; Nakata, S; Ogawa, H; Osuga, T; Shigaki, Y; Tamura, T; Ueno, N; Yoshikawa, T1
Mohanraj, S; Murugan, D; Rajiv, S; Rengarajan, A1
Agostinis, P; Annaert, W; Boulanger, C; Carmeliet, P; De Bock, K; Dejana, E; Dewerchin, M; Garmyn, M; Georgiadou, M; Gerhardt, H; Ghesquière, B; Kuchnio, A; Maes, H; Moens, S; Nys, K; Peric, A; Quaegebeur, A; Radtke, F; Schoors, S; Vankelecom, H; Vinckier, S; Vion, AC; Wouters, J1
Cassinelli, G; De Cesare, M; Lanzi, C; Zaffaroni, N; Zuco, V1
Choate, KA; Ko, CJ; Lim, YH; Odell, ID1
Hagihara, K; Hama, N; Hirao, M; Ikeda, M; Maeda, S; Miyake, M; Miyamoto, A; Miyazaki, M; Nakamori, S; Nishikawa, K; Omiya, H; Sekimoto, M; Takami, K; Uemura, M; Yamamoto, K1
Hayashi, Y; Hirato, J; Kuroiwa, M; Park, MJ; Sakamoto, J; Shimada, A; Sotomatsu, M; Suzuki, N1
Bastien, S; Bicaku, E; Daud, AI; Dawson, J; DeConti, RC; Hausheer, FA; Lush, R; Marchion, D; Munster, PN; Neuger, A; Sullivan, DM1
Hida, T; Kimura, T; Saga, K1
Amschler, K; Erpenbeck, L; Pletz, N; Schön, M; Schön, MP; Wallbrecht, K1
Cichorek, M1
Allen, PJ; Brady, MS; Busam, KJ; Chou, JF; Coit, DG; Fields, RC; Kraus, DH; Panageas, KS; Pulitzer, MP1
Aydiner, A; Camlica, H; Kurul, S; Tas, F; Topuz, E1
Akiyama, T; Doi, T; Hirata, K; Homma, H; Iyama, S; Kida, M; Kogawa, K; Mezawa, S; Murakami, K; Murase, K1
Carano, RA; Koeppen, H; Ross, AL; Ross, J; Schwall, RH; Van Bruggen, N; Williams, SP1
Brodsky, I; Rosenbluth, JZ; Styler, MJ; Zak, D1
Akioka, T; Enomoto, U; Hanafusa, T; Hara, S; Higashi, K; Kiyokane, K; Kusakabe, H; Oka, S; Tsuji, M; Yamano, T; Yokote, T1
Amano, S; Enomoto, K; Negishi, N; Sakurai, K1
Bryl, E; Cichorek, M; Kozłowska, K1
Daoud, SS; Fetouh, MI; Giovanella, BC1
Chen, G; Davis, AW; Gao, XM; Hua, DH; Newell, SW; Perchellet, EM; Perchellet, JP1
Davis, AW; Gao, XM; Hua, DH; Newell, SW; Perchellet, EM; Perchellet, JP1
Ho, V; Li, G; Tang, L; Tron, V; Zhou, X1
Arbuck, S; Argiris, A; Cooper, DL; DiStasio, S; Foss, FM; Heald, P; Kuzel, T; Murren, JR1
Bedikian, AY; Ellerhorst, JA; Eton, O; Papadopoulos, NE; Plager, C; Smith, TM1

Reviews

2 review(s) available for camptothecin and Cancer of Skin

ArticleYear
Combination of gemcitabine and irinotecan for recurrent metastatic osteogenic sarcoma.
    Clinical advances in hematology & oncology : H&O, 2005, Volume: 3, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Cisplatin; Combined Modality Therapy; Deoxycytidine; Doxorubicin; Etoposide; Femoral Neoplasms; Gemcitabine; Head and Neck Neoplasms; Humans; Ifosfamide; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Palliative Care; Salvage Therapy; Scalp; Skin Neoplasms; Thoracotomy

2005
[Two cases of postoperative local skin recurrence of breast cancer successfully treated with chemotherapy of irinotecan hydrochloride (CPT-11)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:11

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Carcinoembryonic Antigen; Drug Resistance, Neoplasm; Female; Humans; Irinotecan; Middle Aged; Mucin-1; Neoplasm Recurrence, Local; Skin Neoplasms

2005

Trials

4 trial(s) available for camptothecin and Cancer of Skin

ArticleYear
Potentiation of a topoisomerase I inhibitor, karenitecin, by the histone deacetylase inhibitor valproic acid in melanoma: translational and phase I/II clinical trial.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Apr-01, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Drug Synergism; Enzyme Inhibitors; Female; Histone Deacetylase Inhibitors; Histones; Humans; Male; Melanoma; Mice; Mice, Nude; Middle Aged; Skin Neoplasms; Topoisomerase I Inhibitors; Valproic Acid

2009
Combination chemotherapy with docetaxel and irinotecan in metastatic malignant melanoma.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2003, Volume: 15, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Docetaxel; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Irinotecan; Male; Melanoma; Middle Aged; Paclitaxel; Skin Neoplasms; Survival Analysis; Taxoids; Treatment Outcome

2003
Phase II trial of 9-aminocamptothecin as a 72-h infusion in cutaneous T-cell lymphoma.
    Investigational new drugs, 2001, Volume: 19, Issue:4

    Topics: Adult; Antineoplastic Agents; Camptothecin; Disease Progression; Female; Granulocyte Colony-Stimulating Factor; Humans; Infusions, Intravenous; Lymphoma, T-Cell, Cutaneous; Male; Middle Aged; Neutropenia; Skin Neoplasms; Time Factors; Treatment Outcome

2001
Phase II trial of 9-nitrocamptothecin (RFS 2000) for patients with metastatic cutaneous or uveal melanoma.
    Anti-cancer drugs, 2002, Volume: 13, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Camptothecin; Diarrhea; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Neutropenia; Skin Neoplasms; Treatment Outcome; Uveal Neoplasms

2002

Other Studies

26 other study(ies) available for camptothecin and Cancer of Skin

ArticleYear
RJT-101, a novel camptothecin derivative, is highly effective in the treatment of melanoma through DNA damage by targeting topoisomerase 1.
    Biochemical pharmacology, 2020, Volume: 171

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line; Cell Line, Tumor; Cell Proliferation; DNA Damage; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Female; Humans; Melanoma; Mice, Inbred C57BL; Mice, Nude; Molecular Structure; Skin Neoplasms; Topoisomerase I Inhibitors; Tumor Burden; Xenograft Model Antitumor Assays

2020
A dermatan sulfate-functionalized biomimetic nanocarrier for melanoma targeted chemotherapy.
    Carbohydrate polymers, 2020, May-01, Volume: 235

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biomimetic Materials; Camptothecin; Cell Proliferation; Dermatan Sulfate; Drug Carriers; Drug Liberation; Drug Screening Assays, Antitumor; Melanoma; Mice; Molecular Structure; Nanoparticles; Particle Size; Skin Neoplasms; Surface Properties; Tumor Cells, Cultured

2020
Cutaneous metastasis of ascending colon cancer harboring a BRAF V600E mutation: A rare case report.
    Medicine, 2020, May-22, Volume: 99, Issue:21

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Fatal Outcome; Female; Fluorouracil; Humans; Leucovorin; Middle Aged; Proto-Oncogene Proteins B-raf; Skin Neoplasms

2020
Nonsurgical treatment of skin cancer with local delivery of bioadhesive nanoparticles.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 02-16, Volume: 118, Issue:7

    Topics: Adhesives; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Squamous Cell; Cell Line, Tumor; Glycerol; Mice; Mice, Inbred C57BL; Nanoparticles; Polyesters; Polymers; Skin Neoplasms

2021
Hyaluronic acid conjugates for topical treatment of skin cancer lesions.
    Science advances, 2021, Volume: 7, Issue:24

    Topics: Administration, Topical; Camptothecin; Doxorubicin; Humans; Hyaluronic Acid; Skin Diseases; Skin Neoplasms

2021
Trop2 Expression in Extramammary Paget's Disease and Normal Skin.
    International journal of molecular sciences, 2021, Jul-19, Volume: 22, Issue:14

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antigens, Neoplasm; Apocrine Glands; Biomarkers, Tumor; Camptothecin; Cell Adhesion Molecules; Female; Gene Expression; Gene Expression Regulation; Hair Follicle; Humans; Immunoconjugates; Keratinocytes; Male; Membrane Glycoproteins; Middle Aged; Paget Disease, Extramammary; Sebaceous Glands; Skin; Skin Neoplasms

2021
Risk factors for severe adverse effects and treatment-related deaths in Japanese patients treated with irinotecan-based chemotherapy: a postmarketing survey.
    Japanese journal of clinical oncology, 2013, Volume: 43, Issue:5

    Topics: Aged; Analysis of Variance; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Asian People; Breast Neoplasms; Camptothecin; Colorectal Neoplasms; Death; Diarrhea; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Irinotecan; Japan; Leukopenia; Logistic Models; Lung Neoplasms; Lymphoma; Male; Middle Aged; Neoplasms; Ovarian Neoplasms; Product Surveillance, Postmarketing; Risk Assessment; Risk Factors; Sex Factors; Skin Neoplasms; Stomach Neoplasms; Thrombocytopenia

2013
[A case of multiple skin metastases from cancer of the descending colon responding to FOLFIRI/cetuximab therapy].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2014, Volume: 111, Issue:1

    Topics: Adenocarcinoma; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colonic Neoplasms; Fatal Outcome; Female; Fluorouracil; Humans; Leucovorin; Middle Aged; Skin Neoplasms

2014
Anticancer activity of starch/poly[N-(2-hydroxypropyl)methacrylamide]: biomaterial film to treat skin cancer.
    International journal of biological macromolecules, 2014, Volume: 70

    Topics: Acrylamides; Animals; Antineoplastic Agents, Phytogenic; Biocompatible Materials; Camptothecin; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Delivery Systems; Humans; Nuclear Magnetic Resonance, Biomolecular; Skin Neoplasms; Spectroscopy, Fourier Transform Infrared; Starch; Thermogravimetry; Vero Cells

2014
Tumor vessel normalization by chloroquine independent of autophagy.
    Cancer cell, 2014, Aug-11, Volume: 26, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Autophagy; Autophagy-Related Protein 5; Camptothecin; Cell Line, Tumor; Cell Proliferation; Chloroquine; Drug Synergism; Endothelial Cells; Endothelium, Vascular; Humans; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; Microtubule-Associated Proteins; Neoplasm Invasiveness; Neovascularization, Pathologic; Receptor, Notch1; Skin Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays

2014
PLK1 is a critical determinant of tumor cell sensitivity to CPT11 and its inhibition enhances the drug antitumor efficacy in squamous cell carcinoma models sensitive and resistant to camptothecins.
    Oncotarget, 2015, Apr-20, Volume: 6, Issue:11

    Topics: Activation, Metabolic; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Line, Tumor; Child; Drug Resistance, Neoplasm; Female; G2 Phase Cell Cycle Checkpoints; Humans; Irinotecan; Mice; Mice, Nude; Molecular Targeted Therapy; Neoplasm Proteins; Polo-Like Kinase 1; Prodrugs; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proteolysis; Proto-Oncogene Proteins; Pteridines; Rhabdomyosarcoma, Embryonal; Sarcoma, Ewing; Skin Neoplasms; Topoisomerase I Inhibitors; Ubiquitination; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays

2015
Somatic p.T771R KDR (VEGFR2) Mutation Arising in a Sporadic Angioma During Ramucirumab Therapy.
    JAMA dermatology, 2015, Volume: 151, Issue:11

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Hemangioma; Humans; Irinotecan; Male; Mutation; Ramucirumab; Rectal Neoplasms; Skin Neoplasms; Vascular Endothelial Growth Factor Receptor-2

2015
[Effectiveness of Irinotecan, S-1, and Bevacizumab for Rectal Cancer with Lung and Skin Metastases after Adjuvant Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Chemotherapy, Adjuvant; Drug Combinations; Female; Humans; Irinotecan; Lung Neoplasms; Middle Aged; Oxonic Acid; Rectal Neoplasms; Skin Neoplasms; Tegafur; Treatment Outcome

2016
Manifestation of alveolar rhabdomyosarcoma as primary cutaneous lesions in a neonate with Beckwith-Wiedemann syndrome.
    Journal of pediatric surgery, 2009, Volume: 44, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Beckwith-Wiedemann Syndrome; Bone Marrow Transplantation; Camptothecin; Cyclophosphamide; Dactinomycin; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Infant, Newborn; Irinotecan; Potassium Channels, Voltage-Gated; Rhabdomyosarcoma, Alveolar; Skin Neoplasms; Transcription, Genetic; Vincristine

2009
Cytokeratin expression patterns in multiple infundibulocystic basal cell carcinoma.
    Journal of cutaneous pathology, 2011, Volume: 38, Issue:3

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Carboplatin; Carcinoma, Basal Cell; Docetaxel; Female; Humans; Immunohistochemistry; Irinotecan; Keratins; Lung Neoplasms; Neoplasms, Second Primary; Skin Neoplasms; Taxoids

2011
NF-kappaB inhibition through proteasome inhibition or IKKbeta blockade increases the susceptibility of melanoma cells to cytostatic treatment through distinct pathways.
    The Journal of investigative dermatology, 2010, Volume: 130, Issue:4

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Boronic Acids; Bortezomib; Camptothecin; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; I-kappa B Kinase; Lung Neoplasms; Melanoma; Mice; NF-kappa B; Oxazines; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Kinase Inhibitors; Pyrazines; Pyridines; Skin Neoplasms

2010
Camptothecin-induced death of amelanotic and melanotic melanoma cells in different phases of cell cycle.
    Neoplasma, 2011, Volume: 58, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Cycle; Cricetinae; Male; Melanoma; Melanoma, Amelanotic; Mesocricetus; Skin Neoplasms

2011
Five hundred patients with Merkel cell carcinoma evaluated at a single institution.
    Annals of surgery, 2011, Volume: 254, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Carcinoma, Merkel Cell; Cisplatin; Etoposide; Female; Follow-Up Studies; Humans; Infusion Pumps; Irinotecan; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Staging; Prospective Studies; Research Design; Skin Neoplasms; Treatment Outcome

2011
[A case of gastric carcinoma with multiple skin, bone, and bilateral ovary metastasis; effective treatment by chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:12

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Ovarian Neoplasms; Prognosis; Quality of Life; Skin Neoplasms; Stomach Neoplasms

2003
Quantification of tumor tissue populations by multispectral analysis.
    Magnetic resonance in medicine, 2004, Volume: 51, Issue:3

    Topics: Adipose Tissue; Animals; Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Disease Models, Animal; fas Receptor; Female; Humans; Irinotecan; Ligands; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Mice; Mice, Nude; Necrosis; Neoplasm Transplantation; Remission Induction; Skin Neoplasms; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Topoisomerase I Inhibitors; Transplantation, Heterologous; Tumor Necrosis Factor-alpha

2004
Irinotecan (CPT-11) in the treatment of mycosis fungoides.
    The British journal of dermatology, 2005, Volume: 153, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Female; Humans; Irinotecan; Male; Middle Aged; Mycosis Fungoides; Skin Neoplasms

2005
The activity of caspases in spontaneous and camptothecin-induced death of melanotic and amelanotic melanoma cell.
    Cancer biology & therapy, 2007, Volume: 6, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Caspases; Cell Line, Tumor; Cricetinae; Cytochromes c; Disease Progression; Flow Cytometry; Male; Melanins; Melanoma, Amelanotic; Melanoma, Experimental; Mesocricetus; Microscopy, Confocal; Poly(ADP-ribose) Polymerases; Skin Neoplasms

2007
Antitumor effect of liposome-incorporated camptothecin in human malignant xenografts.
    Anti-cancer drugs, 1995, Volume: 6, Issue:1

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Breast Neoplasms; Camptothecin; Carcinoma; Cholesterol; Drug Carriers; Drug Evaluation, Preclinical; Humans; Liposomes; Melanoma, Experimental; Mice; Mice, Nude; Molecular Structure; Neoplasm Proteins; Neoplasm Transplantation; Phosphatidylinositols; Remission Induction; Skin Neoplasms; Sphingomyelins; Topoisomerase I Inhibitors

1995
Camptothecin post-treatments inhibit the biochemical events linked to the tumor-promoting component of carcinogenesis in mouse epidermis in vivo.
    International journal of cancer, 1996, May-16, Volume: 66, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Camptothecin; DNA; DNA Adducts; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Induction; Enzyme Inhibitors; Epidermis; Female; Mice; Ornithine Decarboxylase; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors

1996
Characterization of the antitumor-promoting activity of camptothecin in SENCAR mouse skin.
    Carcinogenesis, 1996, Volume: 17, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Diterpenes; DNA Replication; Female; Mice; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors

1996
Chemotherapy-induced apoptosis in melanoma cells is p53 dependent.
    Melanoma research, 1998, Volume: 8, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Cell Division; Cell Survival; Cisplatin; DNA Fragmentation; DNA, Neoplasm; Electrophoresis, Agar Gel; Genes, p53; Humans; Melanocytes; Melanoma; Mutation; Skin Neoplasms; Tumor Cells, Cultured; Vincristine

1998