Page last updated: 2024-08-22

camptothecin and Cancer of Gastrointestinal Tract

camptothecin has been researched along with Cancer of Gastrointestinal Tract in 67 studies

Research

Studies (67)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	10 (14.93)	18.2507
2000's	33 (49.25)	29.6817
2010's	20 (29.85)	24.3611
2020's	4 (5.97)	2.80

Authors

Authors	Studies
Hu, X; Jiang, W; Li, J; Li, S; Peng, Y; Wang, Z; Xiong, Y; Zhang, H	1
Bassali, F; Book, A; Bruckner, HW; De Jager, R; Dusowitz, E; Gurell, D	1
Kitagawa, C; Nishibori, R; Nozawa, K; Sato, M; Shiraishi, K; Sugiyama, K	1
Barra, WF; Burbano, RMR; da Costa Silva, AL; da Costa, DF; de Assumpção, PB; de Assumpção, PP; Dobbin, EAF; Dos Santos, NPC; Dos Santos, SEB; Fernandes, MR; Modesto, AAC; Pastana, LF; Rodrigues, JCG	1
Cervantes, A; Moreno Vera, S; Peeters, M; Taieb, J	1
De Marchis, ML; Ferroni, P; Formica, V; Guadagni, F; La Farina, F; Laudisi, A; Ludovici, G; Palmirotta, R; Peeters, M; Rolfo, C; Roselli, M; Russo, A	1
Duffy, AG; Greten, TF	1
Bendell, JC; Burris, HA; Hoh, CK; Infante, JR; Kim, S; Reid, TR; Rosbrook, B; Tarazi, J	1
Boku, N; Furuse, J; Ishido, K; Kasuga, A; Machida, N; Morizane, C; Nishina, T; Okusaka, T; Sudo, K; Takahashi, H; Tobimatsu, K; Yamaguchi, T	1
Bouquié, R; Boyer, JC; Broly, F; Etienne-Grimaldi, MC; Gagnieu, MC; Gaub, MP; Ged, C; Ghiringhelli, F; Le Guellec, C; Le Morvan, V; Loriot, MA; Philibert, L; Picard, N; Poncet, D; Quaranta, S; Thomas, F	1
Gao, SR; Li, LM; Wang, AR; Wang, GM; Xia, HP; Xu, HY	1
Almhanna, K; Fulp, W; Kim, R; Mahipal, A; Shibata, D; Siegel, E; Springett, G; Williams-Elson, I	1
Borad, MJ; Erlichman, C; Grothey, A; Hubbard, JM; Johnson, E; Kim, G; Lensing, J; Puttabasavaiah, S; Qin, R; Wright, J	1
Lee, JR; Oh, PJ	1
Ahrendt, SA; Bahary, N; Bartlett, DL; Choudry, HA; Dhir, M; Hogg, ME; Holtzman, MP; Pingpank, JF; Singhi, AD; Zeh, HJ; Zureikat, AH	1
Gress, TM; Rinke, A	1
Becerra, CR; Frenkel, EP; Tavana, D; Tran, HT; Verma, UN; Williams, NS	1
Davies, A; Gandara, D; Huynh, M; Johl, J; Lara, P; Lau, D; Tanaka, M	1
Ilson, DH; Kelsen, DP; Kepler, S; O'Reilly, E; Radovich, D; Saltz, LB; Schrag, D; Schwartz, G; Tew, WP	1
Chen, K; Gong, J; Wang, T; Wang, Z; Zheng, Y	1
Akashi, I; Ashizawa, T; Hama, K; Hirano, T; Iwahori, T; Iwamoto, H; Jyojima, Y; Kihara, Y; Konnno, O; Nagao, T; Nakamura, Y; Segawa, M; Takeuchi, H; Yokoyama, T	1
Gallagher, M; Giantonio, B; Haller, DG; Metz, JM; O'Dwyer, PJ; Sun, W; Whittington, R	1
Berglund, A; Byström, P; Einarsson, R; Glimelius, B; Johansson, B; Larsson, A; Nygren, P; Wernroth, L	1
Esaki, T; Hyodo, I; Ishizuka, N; Kakeji, Y; Koizumi, W; Munakata, M; Nishina, T; Okamura, S; Sakata, Y; Sasaki, Y; Satoh, T; Tsujinaka, T; Ura, T; Yamada, Y; Yamazaki, K	1
Chen, L; Duan, G; Huang, C; Jiang, Y; Li, Z; Wang, X	1
Bachmann, E; Galle, PR; Khillimberger, K; Linnig, M; Moehler, M; Mueller, A; Schimanski, CC	1
Bekaii-Saab, T; Blazer, M; Efries, D; Griffith, N; Juergens, K; Phillips, G; Reardon, J; Rose, J; Smith, Y; Weatherby, L	1
Sakata, Y; Satoh, T	1
Höffken, K; Kliche, KO; Kubsch, K; Masri-Zada, R; Raida, M	1
Baker, C; Chun, HG; Fehn, K; Goel, S; Hoffman, A; Hopkins, U; Jhawer, M; Landau, L; Makower, D; Mani, S; Rajdev, L; Wadler, S	1
Armand, JP; Boige, V; Ducreux, M; Faivre, S; Gatineau, M; Jacques, C; Raymond, E; Rixe, O; Sanderink, GJ; Vernillet, L	1
Avallone, A; Casaretti, R; Comella, G; Comella, P; De Rosa, V; Fiore, F; Izzo, F; Lapenta, L	1
Beach, J; Benjamin, RS; Burgess, MA; Jenkins, J; Papadopoulos, N; Patel, SR; Trent, J	1
Pizzolato, JF; Saltz, LB	1
Fanucchi, MP; Giblin, J; Khuri, F; Richards, S; Umbreit, JN	1
Grothey, A; Jordan, K; Kegel, T; Kellner, O; Schmoll, HJ	1
King, CR; Marsh, S; McLeod, HL	1
Fenske, A; Hribaschek, A; Krüger, S; Lippert, H; Meyer, F; Pross, M; Ridwelski, K	1
Gallagher, M; Giantonio, B; Haller, D; Metz, J; O'Dwyer, P; Sun, W; Whittington, R	1
Bertheault-Cvitkovic, F; Bugat, R; Canal, P; Chatelut, E; Cornen, X; Delord, JP; Dieras, V; Guimbaud, R; Lochon, I; Lokiec, F; Mery-Mignard, D; Mouri, Z; Pierga, JY; Turpin, FL	1
Susman, E	1
Berdzik, J; Creaven, PJ; Hoffman, JL; Intengan, ME; Javle, MM; Khushalani, N; Litwin, AM; Pendyala, L; Ramnath, N; Rustum, YM; Slocum, HK; Smith, PF; Stewart, CC; Toth, K	1
Baudin, E; Boige, V; de Baere, T; Dromain, C; Ducreux, MP; Duvillard, P; Elias, D; Kergoat, P; Lasser, P; Leboulleux, S; Malka, D; Sabourin, JC; Schlumberger, M	1
Brunet Vidal, J; Cabezas Montero, I; Gumà Padró, J; Llobera Serentill, M; Manzano Alemany, H; Salud Salvia, A; Servitja Tormo, S; Sopena Bert, E; Valentí Moreno, V	1
Meric, JB	1
Arnold, D; Lordick, F	1
Kono, A; Matsuoka, H; Saito, T; Seo, Y; Takiguchi, S; Tomoda, H; Yano, K	1
Geoffroy, F; Grem, JL	1
Akiyaya, S; Ito, K; Kodera, Y; Kondou, K; Nagai, S; Satta, T; Takagi, H; Yamauchi, M	1
Ogawa, M	1
Sasaki, T	1
Enzinger, PC; Ilson, DH; Kelsen, DP; O'Reilly, EM; Saltz, LB	1
Taguchi, T	2
Armand, JP; Cunningham, D; Kohne, CH; Misset, JL; van Cutsem, E	1
Adenis, A; Conroy, T; Paillot, B	1
Aherne, GW; Benepal, TS; Cunningham, D; Ford, HE; Gruia, G; Massey, A; Price, T; Rao, S; Ross, PJ; Vernillet, L	1
Kajiyama, Y; Tsurumaru, M	1
Cvitkovic, E; Di Palma, M; Goldwasser, F; Gross-Goupil, M; Marceau-Suissa, J; Misset, JL; Tigaud, JM; Wasserman, E; Yovine, A	1
Saltz, LB	1
Rothenberg, ML	1
Ilson, DH; O'Reilly, EM	1
Adam, R; Antoine, EC; Bassot, V; Benhammonda, A; Bismuth, H; Castaing, D; Gil-Delgado, MA; Grapin, JP; Guinet, F; Khayat, D	1
Choy, H; MacRae, R	1
Ajani, JA; Lozano, R; Pro, B	1
Furue, H; Hasegawa, K; Hattori, T; Niitani, H; Ohta, K; Taguchi, T; Wakui, A	1

Reviews

19 review(s) available for camptothecin and Cancer of Gastrointestinal Tract

Article	Year
Trifluridine/tipiracil: an emerging strategy for the management of gastrointestinal cancers. Future oncology (London, England), 2018, Volume: 14, Issue:16 Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Clinical Trials as Topic; Colonic Neoplasms; Docetaxel; Drug Combinations; Fluorouracil; Gastrointestinal Neoplasms; Humans; Immunotherapy; Indoles; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Pyrrolidines; Quality of Life; Taxoids; Thymine; Trifluridine; Uracil	2018
Immunological off-target effects of standard treatments in gastrointestinal cancers. Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:1 Topics: Animals; Antineoplastic Agents; Camptothecin; Cytotoxicity, Immunologic; Deoxycytidine; Fluorouracil; Gastrointestinal Neoplasms; Gemcitabine; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Taxoids; Tumor Escape; Tumor Microenvironment	2014
[Interest of UGT1A1 genotyping within digestive cancers treatment by irinotecan]. Bulletin du cancer, 2014, Volume: 101, Issue:6 Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Asian People; Camptothecin; Colorectal Neoplasms; France; Gastrointestinal Neoplasms; Genotype; Gilbert Disease; Glucuronosyltransferase; Humans; Irinotecan; Pharmacovigilance; Phenotype; Polymorphism, Genetic; Treatment Outcome; United States; White People	2014
Neuroendocrine Cancer, Therapeutic Strategies in G3 Cancers. Digestion, 2017, Volume: 95, Issue:2 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Carcinoma, Neuroendocrine; Cisplatin; Etoposide; Gastrointestinal Neoplasms; Humans; Irinotecan; Ki-67 Antigen; Neoplasm Grading; Neuroendocrine Tumors; Practice Guidelines as Topic; Prognosis; Treatment Outcome	2017
S-1 for the treatment of gastrointestinal cancer. Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:13 Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Combinations; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Practice Guidelines as Topic; Tegafur	2012
The camptothecins. Lancet (London, England), 2003, Jun-28, Volume: 361, Issue:9376 Topics: Animals; Antineoplastic Agents, Phytogenic; Bone Marrow; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Diarrhea; Female; Gastrointestinal Neoplasms; Humans; Lung Neoplasms; Ovarian Neoplasms; Structure-Activity Relationship; Topoisomerase I Inhibitors	2003
Prevention of irinotecan associated diarrhea by intestinal alkalization. A pilot study in gastrointestinal cancer patients. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2006, Volume: 8, Issue:3 Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Diarrhea; Female; Gastrointestinal Neoplasms; Humans; Irinotecan; Male; Middle Aged; Pilot Projects; Prospective Studies; Sodium Bicarbonate	2006
[Angiogenesis targeting in gastro-intestinal cancers]. Bulletin du cancer, 2007, Volume: 94, Issue:7 Suppl Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Carcinoma, Hepatocellular; Colorectal Neoplasms; Esophageal Neoplasms; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Neovascularization, Pathologic; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Stomach Neoplasms	2007
Chemotherapy of advanced gastrointestinal cancer. Current opinion in oncology, 1994, Volume: 6, Issue:4 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Clinical Trials as Topic; Combined Modality Therapy; Digestive System Neoplasms; Double-Blind Method; Drugs, Investigational; Gastrointestinal Neoplasms; Humans; Immunologic Factors; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Neoplasm Metastasis; Pancreatic Neoplasms; Prospective Studies; Survival Rate; Treatment Outcome	1994
New systemic drugs in the treatment of gastrointestinal cancer. Current opinion in oncology, 1996, Volume: 8, Issue:4 Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Clinical Trials as Topic; Docetaxel; Gastrointestinal Neoplasms; Humans; Irinotecan; Paclitaxel; Quinazolines; Taxoids; Thiophenes; Thymidylate Synthase	1996
[New anti-cancer drugs for gastrointestinal cancers]. Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:13 Topics: Amino Acids; Antidotes; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Clinical Trials, Phase II as Topic; Docetaxel; Drug Administration Schedule; Fluorouracil; Gastrointestinal Neoplasms; Humans; Interferons; Irinotecan; Leucovorin; Paclitaxel; Taxoids	1997
Irinotecan and cisplatin in upper gastrointestinal malignancies. Oncology (Williston Park, N.Y.), 1998, Volume: 12, Issue:8 Suppl 6 Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Cisplatin; Drug Therapy, Combination; Gastrointestinal Neoplasms; Humans; Irinotecan	1998
[Gastrointestinal cancer and oral anticancer agents]. Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:3 Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Agents; Camptothecin; Drug Combinations; Floxuridine; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Organoplatinum Compounds; Oxonic Acid; Prodrugs; Pyridines; Tegafur; Uracil	1999
Clinical advances with topoisomerase I inhibitors in gastrointestinal malignancies. Anti-cancer drugs, 1999, Volume: 10 Suppl 1 Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Docetaxel; Enzyme Inhibitors; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Platinum; Quinazolines; Taxoids; Thiophenes; Topoisomerase I Inhibitors	1999
[New drugs in gastrointestinal oncology. Current status and future directions]. Gastroenterologie clinique et biologique, 1999, Volume: 23, Issue:11 Topics: Antineoplastic Agents; Camptothecin; Capecitabine; Deoxycytidine; Docetaxel; Floxuridine; Fluorouracil; Gastrointestinal Neoplasms; Gemcitabine; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Quinazolines; Taxoids; Tegafur; Thiophenes; Vinblastine; Vinorelbine	1999
[Outpatient treatment for gastrointestinal tract cancer in the Department of Surgery]. Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:11 Topics: Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Cisplatin; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Lymphatic Metastasis; Quality of Life	2000
Irinotecan (CPT-11): recent developments and future directions--colorectal cancer and beyond. The oncologist, 2001, Volume: 6, Issue:1 Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Clinical Trials as Topic; Colorectal Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Drug Therapy, Combination; Gastrointestinal Neoplasms; Humans; Irinotecan; Lung Neoplasms	2001
Cisplatin and irinotecan in upper gastrointestinal malignancies. Oncology (Williston Park, N.Y.), 2001, Volume: 15, Issue:3 Suppl 5 Topics: Antineoplastic Agents; Camptothecin; Cisplatin; Drug Therapy, Combination; Gastrointestinal Neoplasms; Humans; Irinotecan	2001
Irinotecan and radiation in combined-modality therapy for solid tumors. Oncology (Williston Park, N.Y.), 2001, Volume: 15, Issue:7 Suppl 8 Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Non-Small-Cell Lung; Drug Administration Schedule; Enzyme Inhibitors; Female; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Irinotecan; Lung Neoplasms; Male; Neoplasms; Radiotherapy, Adjuvant; Topoisomerase I Inhibitors; Uterine Cervical Neoplasms	2001

Trials

28 trial(s) available for camptothecin and Cancer of Gastrointestinal Tract

Article	Year
Intermittent dosing of axitinib combined with chemotherapy is supported by (18)FLT-PET in gastrointestinal tumours. British journal of cancer, 2014, Feb-18, Volume: 110, Issue:4 Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Axitinib; Bevacizumab; Camptothecin; Female; Fluorodeoxyglucose F18; Fluorouracil; Gastrointestinal Neoplasms; Humans; Imidazoles; Indazoles; Leucovorin; Male; Maximum Tolerated Dose; Middle Aged; Organoplatinum Compounds; Positron-Emission Tomography; Protein Kinase Inhibitors; Radiopharmaceuticals; Withholding Treatment	2014
Multicenter retrospective analysis of systemic chemotherapy for advanced neuroendocrine carcinoma of the digestive system. Cancer science, 2014, Volume: 105, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Carcinoma, Neuroendocrine; Cisplatin; Deoxycytidine; Disease-Free Survival; Etoposide; Female; Fluorouracil; Gastrointestinal Neoplasms; Gemcitabine; Humans; Irinotecan; Kaplan-Meier Estimate; Leucovorin; Male; Organoplatinum Compounds; Oxaliplatin; Prognosis; Proportional Hazards Models; Retrospective Studies; Treatment Outcome	2014
Phase I trial of combination of FOLFIRI and pasireotide, a somatostatin analogue, in advanced gastrointestinal malignancies. Investigational new drugs, 2015, Volume: 33, Issue:5 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Dose-Response Relationship, Drug; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Insulin-Like Growth Factor I; Leucovorin; Male; Maximum Tolerated Dose; Middle Aged; Somatostatin; Survival Analysis	2015
Phase I trial of FOLFIRI in combination with sorafenib and bevacizumab in patients with advanced gastrointestinal malignancies. Investigational new drugs, 2016, Volume: 34, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Leucovorin; Male; Maximum Tolerated Dose; Middle Aged; Niacinamide; Phenylurea Compounds; Sorafenib; Treatment Outcome	2016
Phase I dose escalation study with irinotecan, capecitabine, epirubicin, and granulocyte colony-stimulating factor support for patients with solid malignancies. American journal of clinical oncology, 2008, Volume: 31, Issue:3 Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Breast Neoplasms; Camptothecin; Capecitabine; Deoxycytidine; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Administration Schedule; Drug Resistance, Neoplasm; Drug Synergism; Epirubicin; Female; Fluorouracil; Gastrointestinal Diseases; Gastrointestinal Neoplasms; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Humans; Infusions, Intravenous; Irinotecan; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Topoisomerase II Inhibitors; Treatment Outcome	2008
Population-based phase I trial of irinotecan and epirubicin. American journal of clinical oncology, 2008, Volume: 31, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Asthenia; Camptothecin; Carcinoma, Non-Small-Cell Lung; Diarrhea; Drug Administration Schedule; Drug Synergism; Epirubicin; Female; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Irinotecan; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Nausea; Neutropenia; Topoisomerase I Inhibitors	2008
Phase I trial of weekly cisplatin, irinotecan and paclitaxel in patients with advanced gastrointestinal cancer. Investigational new drugs, 2009, Volume: 27, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Dose-Response Relationship, Drug; Female; Gastrointestinal Neoplasms; Humans; Irinotecan; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Neutropenia; Paclitaxel	2009
Irinotecan hydrochloride (CPT-11) in dialysis patients with gastrointestinal cancer. Acta medica Okayama, 2010, Volume: 64, Issue:1 Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Female; Gastrointestinal Neoplasms; Humans; Irinotecan; Kidney Failure, Chronic; Leukopenia; Male; Middle Aged; Rectal Neoplasms; Renal Dialysis; Stomach Neoplasms	2010
Two phase I studies of concurrent radiation therapy with continuous-infusion 5-fluorouracil plus epirubicin, and either cisplatin or irinotecan for locally advanced upper gastrointestinal adenocarcinomas. Cancer chemotherapy and pharmacology, 2011, Volume: 67, Issue:3 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Combined Modality Therapy; Dose-Response Relationship, Drug; Epirubicin; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Infusions, Intravenous; Irinotecan; Male; Maximum Tolerated Dose; Middle Aged	2011
An explorative study on the clinical utility of baseline and serial serum tumour marker measurements in advanced upper gastrointestinal cancer. Oncology reports, 2010, Volume: 24, Issue:6 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Pharmacological; Biomarkers, Tumor; Blood Chemical Analysis; Camptothecin; Disease Progression; Docetaxel; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Predictive Value of Tests; Prognosis; Taxoids; Upper Gastrointestinal Tract	2010
Genotype-directed, dose-finding study of irinotecan in cancer patients with UGT1A128 and/or UGT1A16 polymorphisms. Cancer science, 2011, Volume: 102, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Alleles; Antineoplastic Agents, Phytogenic; Camptothecin; Female; Gastrointestinal Neoplasms; Genotype; Glucuronosyltransferase; Humans; Irinotecan; Male; Maximum Tolerated Dose; Middle Aged; Polymorphism, Single Nucleotide	2011
Effects of sequential chemotherapy of FOLFIRI/FOLFOX on the endocrine axes of ACTH-cortisol and renin-angiotensin-aldosterone. Journal of neuro-oncology, 2012, Volume: 108, Issue:3 Topics: Adrenocorticotropic Hormone; Aged; Aldosterone; Angiotensins; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Case-Control Studies; Fluorouracil; Gastrointestinal Neoplasms; Humans; Hydrocortisone; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Prognosis; Renin	2012
Antiemetic control with palonosetron in patients with gastrointestinal cancer receiving a fluoropyrimidine-based regimen in addition to either irinotecan or oxaliplatin: a retrospective study. Oncology, 2012, Volume: 83, Issue:3 Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Deoxycytidine; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Isoquinolines; Male; Middle Aged; Nausea; Ondansetron; Organoplatinum Compounds; Oxaliplatin; Palonosetron; Quinuclidines; Retrospective Studies; Treatment Outcome	2012
Chronomodulated chemotherapy in metastatic gastrointestinal cancer combining 5-FU and sodium folinate with oxaliplatin, irinotecan or gemcitabine: the Jena experience in 79 patients. Journal of cancer research and clinical oncology, 2002, Volume: 128, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Camptothecin; Colorectal Neoplasms; Deoxycytidine; Female; Fluorouracil; Folic Acid; Gastrointestinal Neoplasms; Gemcitabine; Humans; Irinotecan; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Stomach Neoplasms	2002
Phase I clinical trial of irinotecan with oral capecitabine in patients with gastrointestinal and other solid malignancies. American journal of clinical oncology, 2002, Volume: 25, Issue:5 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Deoxycytidine; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Infusions, Intravenous; Irinotecan; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged	2002
Dosage adjustment and pharmacokinetic profile of irinotecan in cancer patients with hepatic dysfunction. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Nov-01, Volume: 20, Issue:21 Topics: Adult; Aged; Alkaline Phosphatase; Antineoplastic Agents, Phytogenic; Bilirubin; Camptothecin; Dose-Response Relationship, Drug; Female; Gastrointestinal Neoplasms; Humans; Hyperbilirubinemia; Irinotecan; Male; Middle Aged; Predictive Value of Tests	2002
Oxaliplatin plus irinotecan and leucovorin-modulated 5-fluorouracil triplet regimen every other week: a dose-finding study in patients with advanced gastrointestinal malignancies. Annals of oncology : official journal of the European Society for Medical Oncology, 2002, Volume: 13, Issue:12 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Camptothecin; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Infusions, Intravenous; Irinotecan; Leucovorin; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Prognosis; Pyridines; Survival Analysis; Treatment Outcome	2002
Results of a 2-arm Phase II study of 9-nitrocamptothecin in patients with advanced soft-tissue sarcomas. Cancer, 2003, Jun-01, Volume: 97, Issue:11 Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Camptothecin; Female; Gastrointestinal Neoplasms; Humans; Leiomyosarcoma; Male; Middle Aged; Sarcoma; Soft Tissue Neoplasms; Topoisomerase I Inhibitors; Treatment Outcome	2003
Phase II trial of capecitabine/irinotecan and capecitabine/oxaliplatin in advanced gastrointestinal cancers. Clinical colorectal cancer, 2004, Volume: 4, Issue:1 Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Deoxycytidine; Diarrhea; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Salvage Therapy; Treatment Outcome	2004
Concurrent RT with 5-FU/epirubicin and cisplatin or irinotecan for locally advanced upper GI adenocarcinoma. Oncology (Williston Park, N.Y.), 2004, Volume: 18, Issue:14 Suppl 1 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Cisplatin; Dose-Response Relationship, Drug; Epirubicin; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Male; Middle Aged; Radiotherapy, Adjuvant; Treatment Outcome; Upper Gastrointestinal Tract	2004
A phase I clinical and pharmacokinetic study of capecitabine (Xeloda) and irinotecan combination therapy (XELIRI) in patients with metastatic gastrointestinal tumours. British journal of cancer, 2005, Mar-14, Volume: 92, Issue:5 Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Camptothecin; Capecitabine; Deoxycytidine; Dose-Response Relationship, Drug; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Middle Aged; Neoplasm Metastasis; Patient Selection; Prodrugs; Safety	2005
S-phase modulation by irinotecan: pilot studies in advanced solid tumors. Cancer chemotherapy and pharmacology, 2005, Volume: 56, Issue:5 Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cyclin A; Deoxycytidine; Female; Fluorouracil; Gastrointestinal Neoplasms; Gemcitabine; Humans; Irinotecan; Male; Maximum Tolerated Dose; Respiratory Tract Neoplasms; S Phase	2005
A phase II study of irinotecan with 5-fluorouracil and leucovorin in patients with pretreated gastroenteropancreatic well-differentiated endocrine carcinomas. Oncology, 2006, Volume: 70, Issue:2 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma; Drug Administration Schedule; Enteroendocrine Cells; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Infusions, Intravenous; Irinotecan; Leucovorin; Lung Neoplasms; Male; Middle Aged; Pancreatic Neoplasms; Prospective Studies; Survival Analysis; Treatment Failure; Treatment Outcome	2006
Prevention of irinotecan associated diarrhea by intestinal alkalization. A pilot study in gastrointestinal cancer patients. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2006, Volume: 8, Issue:3 Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Diarrhea; Female; Gastrointestinal Neoplasms; Humans; Irinotecan; Male; Middle Aged; Pilot Projects; Prospective Studies; Sodium Bicarbonate	2006
Phase I study of irinotecan and raltitrexed in patients with advanced gastrointestinal tract adenocarcinoma. British journal of cancer, 2000, Volume: 83, Issue:2 Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Gastrointestinal Neoplasms; Humans; Irinotecan; Male; Middle Aged; Quinazolines; Survival Rate; Thiophenes; Treatment Outcome	2000
Dose escalation of CPT-11 in combination with oxaliplatin using an every two weeks schedule: a phase I study in advanced gastrointestinal cancer patients. Annals of oncology : official journal of the European Society for Medical Oncology, 2000, Volume: 11, Issue:11 Topics: Adult; Aged; Alopecia; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Diarrhea; Drug Administration Schedule; Drug Resistance, Neoplasm; Esophageal Neoplasms; Female; Fluorouracil; Gastrointestinal Neoplasms; Hematologic Diseases; Humans; Infections; Irinotecan; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Neutropenia; Organoplatinum Compounds; Oxaliplatin; Salvage Therapy; Sensation Disorders; Treatment Outcome	2000
Phase I-II study of irinotecan in combination with mitomycin C in patients with advanced gastrointestinal cancer. American journal of clinical oncology, 2001, Volume: 24, Issue:3 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Gastrointestinal Neoplasms; Humans; Irinotecan; Male; Middle Aged; Mitomycin; Neoplasm Staging	2001
[Phase I clinical study of CPT-11. Research group of CPT-11]. Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:1 Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Drug Evaluation; Female; Gastrointestinal Neoplasms; Humans; Irinotecan; Japan; Lung Neoplasms; Male; Middle Aged; Multicenter Studies as Topic; Neoplasms	1990

Other Studies

21 other study(ies) available for camptothecin and Cancer of Gastrointestinal Tract

Article	Year
Journal of medicinal chemistry, 2022, 08-11, Volume: 65, Issue:15 Topics: Animals; Anti-Inflammatory Agents; Benzamides; Cyclooxygenase 2; Dinoprostone; DNA Topoisomerases, Type I; Enzyme Inhibitors; Gastrointestinal Neoplasms; Inflammation; Lipopolysaccharides; Mice; NF-kappa B; Signal Transduction; Topoisomerase I Inhibitors	2022
Actionable tests and treatments for patients with gastrointestinal cancers and historically short median survival times. PloS one, 2022, Volume: 17, Issue:11 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colorectal Neoplasms; Fluorouracil; Gastrointestinal Neoplasms; Humans; Leucovorin	2022
Salvage Chemotherapy by FOLFIRI Regimen for Poorly Differentiated Gastrointestinal Neuroendocrine Carcinoma. Journal of gastrointestinal cancer, 2021, Volume: 52, Issue:3 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Neuroendocrine; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Japan; Leucovorin; Male; Middle Aged; Retrospective Studies; Salvage Therapy; Treatment Outcome	2021
Influence of FPGS, ABCC4, SLC29A1, and MTHFR genes on the pharmacogenomics of fluoropyrimidines in patients with gastrointestinal cancer from the Brazilian Amazon. Cancer chemotherapy and pharmacology, 2021, Volume: 88, Issue:5 Topics: Antineoplastic Combined Chemotherapy Protocols; Brazil; Camptothecin; Equilibrative Nucleoside Transporter 1; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Leucovorin; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multidrug Resistance-Associated Proteins; Organoplatinum Compounds; Peptide Synthases; Pharmacogenomic Variants; Polymorphism, Single Nucleotide	2021
TNF-α gene promoter polymorphisms and risk of venous thromboembolism in gastrointestinal cancer patients undergoing chemotherapy. Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Case-Control Studies; Female; Fluorouracil; Gastrointestinal Neoplasms; Genetic Predisposition to Disease; Haplotypes; Humans; Irinotecan; Male; Middle Aged; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Retrospective Studies; Risk; Tumor Necrosis Factor-alpha; Venous Thromboembolism	2013
Clinical observation on recombinant human endostatin combined with chemotherapy for advanced gastrointestinal cancer. Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:9 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Therapy; Endostatins; Female; Fluorouracil; Follow-Up Studies; Gastrointestinal Neoplasms; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Recombinant Proteins; Survival Rate	2015
[Effect of Cancer Symptoms and Fatigue on Chemotherapy-related Cognitive Impairment and Depression in People with Gastrointestinal Cancer]. Journal of Korean Academy of Nursing, 2016, Volume: 46, Issue:3 Topics: Adult; Aged; Anemia; Antineoplastic Agents; Anxiety; Camptothecin; Cognitive Dysfunction; Depression; Drug Therapy, Combination; Fatigue; Female; Fluorouracil; Gastrointestinal Neoplasms; Hemoglobins; Humans; Irinotecan; Male; Memory; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Surveys and Questionnaires; Translating	2016
Impact of genomic profiling on the treatment and outcomes of patients with advanced gastrointestinal malignancies. Cancer medicine, 2017, Volume: 6, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Female; Fluorouracil; Gastrointestinal Neoplasms; Genomics; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Molecular Targeted Therapy; Organoplatinum Compounds; Pancreatectomy; Precision Medicine; Sequence Analysis, DNA; Survival Analysis; Treatment Outcome	2017
Combined arterial infusion and stent implantation compared with metal stent alone in treatment of malignant gastroduodenal obstruction. Cardiovascular and interventional radiology, 2009, Volume: 32, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Angiography; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Therapy; Doxorubicin; Duodenal Obstruction; Female; Femoral Artery; Fluoroscopy; Fluorouracil; Gastrointestinal Neoplasms; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Palliative Care; Prosthesis Design; Radiography, Interventional; Retrospective Studies; Statistics, Nonparametric; Stents; Survival Rate; Treatment Outcome	2009
Selective PI3K inhibition by BKM120 and BEZ235 alone or in combination with chemotherapy in wild-type and mutated human gastrointestinal cancer cell lines. Cancer chemotherapy and pharmacology, 2012, Volume: 69, Issue:6 Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Caspase 3; Cell Cycle Checkpoints; Cell Survival; Dose-Response Relationship, Drug; Gastrointestinal Neoplasms; HCT116 Cells; HT29 Cells; Humans; Imidazoles; Irinotecan; Morpholines; Mutation; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinolines; Signal Transduction; TOR Serine-Threonine Kinases	2012
Selective serotonin reuptake inhibitor-induced rhabdomyolysis associated with irinotecan. Southern medical journal, 2003, Volume: 96, Issue:10 Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Citalopram; Depressive Disorder; Drug Interactions; Gastrointestinal Neoplasms; Humans; Irinotecan; Male; Rhabdomyolysis; Selective Serotonin Reuptake Inhibitors	2003
Application of pharmacogenomics in the individualization of chemotherapy for gastrointestinal malignancies. Clinical colorectal cancer, 2004, Volume: 4 Suppl 1 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Pharmacogenetics	2004
[Five cytostatic substances in animal studies for prevention and treatment of experimentally induced peritoneal carcinomatosis]. Zentralblatt fur Chirurgie, 2004, Volume: 129, Issue:4 Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Cisplatin; Data Interpretation, Statistical; Fluorouracil; Gastrointestinal Neoplasms; Irinotecan; Male; Mitomycin; Neoplasm Transplantation; Organoplatinum Compounds; Oxaliplatin; Peritoneal Neoplasms; Rats; Time Factors; Tumor Cells, Cultured	2004
Gastrointestinal Cancers--Second Annual Symposium. 27-29 January 2005, Hollywood, FL, USA. IDrugs : the investigational drugs journal, 2005, Volume: 8, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Therapy; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Randomized Controlled Trials as Topic	2005
[New chances in therapy of gastrointestinal tumors]. Krankenpflege Journal, 2005, Volume: 43, Issue:7-10 Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Fluorouracil; Follow-Up Studies; Gastrointestinal Neoplasms; Humans; Irinotecan; Leucovorin; Neoplasm Staging; Randomized Controlled Trials as Topic	2005
[Systemic treatment of peritoneal metastases]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2007, Volume: 78, Issue:12 Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Gastrointestinal Neoplasms; Humans; Infusions, Intravenous; Irinotecan; Leucovorin; Neoplasm Staging; Peritoneal Neoplasms; Prognosis; Quality of Life	2007
Cytotoxicity of CPT-11 for gastrointestinal cancer cells cultured on fixed-contact-sensitive plates. Anti-cancer drugs, 1995, Volume: 6, Issue:3 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Survival; Colony-Forming Units Assay; Gastrointestinal Neoplasms; Humans; Irinotecan; Mice; Mice, Inbred BALB C; Survival Analysis; Thymidine; Tumor Cells, Cultured; Tumor Stem Cell Assay	1995
Growth inhibition of human gastrointestinal cancer xenograft lines by treatment with CPT-11 and VP-16. Journal of surgical oncology, 1993, Volume: 54, Issue:4 Topics: Adult; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Etoposide; Female; Gastrointestinal Neoplasms; Humans; Irinotecan; Male; Mice; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous; Tumor Cells, Cultured	1993
Irinotecan: a new agent comes of age. The oncologist, 2001, Volume: 6, Issue:1 Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Clinical Trials as Topic; Female; Gastrointestinal Neoplasms; Humans; International Cooperation; Irinotecan; Male; Ovarian Neoplasms; Uterine Cervical Neoplasms	2001
Therapeutic response to octreotide in patients with refractory CPT-11 induced diarrhea. Investigational new drugs, 2001, Volume: 19, Issue:4 Topics: Adult; Aged; Antidiarrheals; Antineoplastic Agents, Phytogenic; Camptothecin; Diarrhea; Female; Gastrointestinal Neoplasms; Humans; Irinotecan; Male; Middle Aged; Octreotide; Treatment Outcome	2001
Recent development of anti-cancer drugs for treatment of GI malignancies in Japan. Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29 Suppl 1 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Capecitabine; Deoxycytidine; Drug Combinations; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Pyridines; Tegafur	2002