Page last updated: 2024-08-22

camptothecin and Bladder Cancer

camptothecin has been researched along with Bladder Cancer in 48 studies

Research

Studies (48)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (4.17)	18.7374
1990's	8 (16.67)	18.2507
2000's	17 (35.42)	29.6817
2010's	12 (25.00)	24.3611
2020's	9 (18.75)	2.80

Authors

Authors	Studies
Bandrés, E; Chozas, H; Cordeu, L; Cubedo, E; Echeverría, M; Font, M; García-Foncillas, J; Mendivil, B; Palop, JA; Rebollo, A; Sáenz, X; Sanmartin, C; Victoria Domínguez, M	1
Boudreau, J; Bulin, J; Hanna, KS; Larson, S; Nguyen, J; Rolf, M	1
Agarwal, N; Mathew Thomas, V; Swami, U; Tripathi, N	1
Cao, M; Fan, M; Hu, Z; Huang, W; Jin, X; Wang, F; Wu, H; Zhang, Y	1
Al-Ahmadie, H; Almassi, N; Alvim, R; Audenet, F; Bagrodia, A; Chen, Z; Clinton, TN; Cocco, E; Coleman, JA; Dason, S; Dong, Y; Elzein, A; Gao, J; Gao, SP; Gordon, B; Hakimi, AA; Hanrahan, AJ; Hsieh, JJ; Hu, W; Hughes, C; Iyer, G; Jebiwott, S; Kim, K; Mohan, V; Murray, K; Nagar, K; Ostrovnaya, I; Penson, A; Pietzak, EJ; Rosenberg, JE; Sagi, I; Santin, AD; Scaltriti, M; Solit, DB; Vargas, HA; Watson, PA; Wong, N	1
Cookson, E	1
Gross-Goupil, M; Thibault, C	1
Bednova, O; Leyton, JV	1
Ding, D; Gao, Z; Li, C; Liu, Q; Ou, H; Zeng, S; Zhang, J	1
Agarwal, N; Grivas, P; Pal, SK; Swami, U	1
Gu, CX; Mo, DL; Pan, CX; Peng, Y; Qian, G; Qin, JK; Su, GF; Wei, K; Yuan, JM; Zhang, GH; Zhou, ZP	1
Ding, Y; Gao, W; Li, D; Sun, Y; Wang, T; Wang, Z; Wei, J; Yang, Y	1
Hasegawa, M; Hattori, S; Ide, H; Kikuchi, E; Miyajima, A; Oya, M; Yasumizu, Y	1
Faltas, B; Goldenberg, DM; Govindan, SV; Hajdenberg, J; Hodes, G; Nanus, DM; Ocean, AJ; Sharkey, RM; Tagawa, ST; Wilhelm, F	1
Chang, IH; Chi, BH; Choi, SS; Kim, KD; Kim, SU; Lee, HJ; Lee, SR	1
Chen, J; Chen, X; Ding, J; Guo, H; Hou, Y; Xu, W; Yan, L	1
Bolognese, A; Caputo, M; Di Cello, P; Izzo, L; Izzo, P; Meloni, P; Pietrasanta, D	1
Jin, HS; Wang, XW; Yan, ZL; Ye, G; Yi, SH; Zhang, YN	1
Chen, KC; Prijovich, ZM; Roffler, SR	1
He, QJ; Jiang, H; Li, LJ; Yang, B; Zhang, C; Zhu, H; Zhu, Y	1
Cao, M; Chen, HG; Ma, CK; Ma, J; Xue, W	1
Bhattacharyya, M; Mutsvangwa, K; Oliver, T; Powles, T; Shamash, J; Wilson, P	1
Albanes, D; Baris, D; Black, A; Burdett, L; Carrato, A; Chanock, SJ; Chatterjee, N; De Vivo, I; Diver, WR; Figueroa, JD; Fraumeni, JF; Fu, YP; Gapstur, SM; Garcia-Closas, M; Garcia-Closas, R; Hall, JL; Hunter, DJ; Hutchinson, A; Jacobs, EJ; Johnson, A; Karagas, MR; Kogevinas, M; Liu, L; Lloreta, J; Malats, N; Myers, T; Porter-Gill, P; Prokunina-Olsson, L; Purdue, MP; Rothman, N; Schned, A; Schwenn, M; Serra, C; Silverman, DT; Tang, W; Tardón, A; Thun, M; Virtamo, J	1
Li, J; Liu, Y; Ye, G; Zhang, J	1
Chaudhary, UB; Gudena, V; Keane, T; Verma, N	1
Fu, Q; Gao, JY; Gao, XP; Lei, YH; Li, JQ; Li, YM; Shao, C; Shi, CH; Shi, JG; Wang, H; Wang, JY; Wang, Y; Xu, P; Xue, W; Yuan, JL; Zhang, W; Zhang, YT	1
Austin, RC; Baumeister, P; Kaufman, RJ; Lee, AS; Mao, C; Reddy, RK	1
Beretta, GL; Brigliadori, G; Corna, E; De Cesare, M; Fabbri, F; Ricotti, L; Rosetti, M; Supino, R; Tesei, A; Ulivi, P; Zoli, W; Zunino, F	1
Hasegawa, Y; Hayashi, N; Kato, Y; Wakita, T	1
Kamoto, T; Kawahara, T; Nishiyama, H; Ogawa, O; Yamamoto, S	1
Goi, T; Hirono, Y; Iida, A; Ishida, M; Katayama, K; Maeda, H; Murakami, M; Obata, S; Yamaguchi, A	1
Funahashi, M; Murayama, T; Yamada, T	1
Huang, H; Liang, ZK; Tan, WL; Zhu, WH	1
Cao, Y; Chen, F; Payne, R; See, WA; Zhang, G	1
Mohile, SG; Petrylak, DP; Schleicher, L	1
Evans, A; Johnson, RT; Ryan, AJ; Squires, S; Strutt, HL	1
Asakuno, K; Kohno, K; Kotoh, S; Kumazawa, J; Kuwano, M; Naito, S; Yokomizo, A	1
Abi-Aad, AS	1
Tannock, IF; Vukovic, V	1
Dillahey, D; El-Galley, RE; Gomaa, A; Graham, SD; Keane, TE; McGuire, WP; Petros, JA; Sun, C	1
Fan, J; Tang, X; Zhang, X	1
Firby, PS; Horn, L; Li, ML; Moore, MJ	1
Wang, X; Xu, A; Yu, M	1
Fan, J; Ling, G; Tang, X; Wang, X; Wang, Y; Xu, D; Zhang, X	1
Misset, JL	1
Ching-chiang, Y; Hsien-you, C; Kui-ming, L; Pao-hua, C; Tung, H	1
Musk, SR; Steel, GG	1
Feng, T; Gu, FL; Shi, T; Wu, JP	1

Reviews

6 review(s) available for camptothecin and Bladder Cancer

Article	Year
The role of enfortumab vedotin and sacituzumab govitecan in treatment of advanced bladder cancer. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2022, 04-01, Volume: 79, Issue:8 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Camptothecin; Carcinoma, Transitional Cell; Humans; Immunoconjugates; Urinary Bladder Neoplasms	2022
Current and emerging role of sacituzumab govitecan in the management of urothelial carcinoma. Expert review of anticancer therapy, 2022, Volume: 22, Issue:4 Topics: Antibodies, Monoclonal, Humanized; Camptothecin; Carcinoma, Transitional Cell; Clinical Trials, Phase II as Topic; Diarrhea; Humans; Immunoconjugates; Irinotecan; Neutropenia; Urinary Bladder Neoplasms	2022
[Innovations in systemic treatment of urothelial carcinoma]. Bulletin du cancer, 2020, Volume: 107, Issue:5S Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Camptothecin; Carcinoma, Transitional Cell; Humans; Immunoconjugates; Immunotherapy; Receptors, Fibroblast Growth Factor; Therapies, Investigational; Urinary Bladder Neoplasms	2020
Targeted Molecular Therapeutics for Bladder Cancer-A New Option beyond the Mixed Fortunes of Immune Checkpoint Inhibitors? International journal of molecular sciences, 2020, Oct-01, Volume: 21, Issue:19 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, Neoplasm; B7-H1 Antigen; Camptothecin; Cell Adhesion Molecules; Gene Expression Regulation, Neoplastic; Humans; Immune Checkpoint Inhibitors; Immunoconjugates; Immunotherapy; Lymphatic Metastasis; Molecular Targeted Therapy; Programmed Cell Death 1 Receptor; Pyrazoles; Quinoxalines; Urinary Bladder; Urinary Bladder Neoplasms	2020
Chemotherapy for advanced bladder carcinoma: new molecules and regimens. Acta urologica Belgica, 1996, Volume: 64, Issue:2 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Transitional Cell; Cisplatin; Deoxycytidine; Doxorubicin; Folic Acid Antagonists; Gallium; Gemcitabine; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Methotrexate; Paclitaxel; Urinary Bladder Neoplasms; Vinblastine	1996
Brief communication: use of the multitargeted antifolate pemetrexed (Alimta) in genitourinary cancer. Seminars in oncology, 2002, Volume: 29, Issue:1 Suppl 3 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Cisplatin; Clinical Trials, Phase II as Topic; Deoxycytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Folic Acid Antagonists; Gemcitabine; Glutamates; Guanine; Humans; Irinotecan; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Pemetrexed; Survival Analysis; Treatment Outcome; Urinary Bladder Neoplasms; Urogenital Neoplasms	2002

Trials

4 trial(s) available for camptothecin and Bladder Cancer

Article	Year
Sacituzumab Govitecan, a Novel Antibody--Drug Conjugate, in Patients With Metastatic Platinum-Resistant Urothelial Carcinoma. Clinical genitourinary cancer, 2016, Volume: 14, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Transitional Cell; Disease-Free Survival; Drug Resistance, Neoplasm; Humans; Immunoconjugates; Lymphatic Metastasis; Male; Treatment Outcome; Urinary Bladder Neoplasms	2016
[Evaluation of the efficacy and safety of intravesical instillation with gemcitabine after first-line intravesical chemotherapy failure in the treatment of non-muscle-invasive bladder cancer]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2011, Volume: 33, Issue:5 Topics: Administration, Intravesical; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Deoxycytidine; Disease-Free Survival; Dose-Response Relationship, Drug; Epirubicin; Female; Follow-Up Studies; Gemcitabine; Humans; Male; Middle Aged; Mitomycin; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Urinary Bladder Neoplasms	2011
A phase II study of mitomycin, fluorouracil, folinic acid, and irinotecan (MFI) for the treatment of transitional cell carcinoma of the bladder. Urologic oncology, 2013, Volume: 31, Issue:6 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Camptothecin; Carcinoma, Transitional Cell; Cisplatin; Female; Fluorouracil; Humans; Irinotecan; Male; Middle Aged; Mitomycin; Time Factors; Treatment Outcome; Urinary Bladder Neoplasms; Urologic Neoplasms	2013
A phase II study of gemcitabine and irinotecan in patients with locally advanced or metastatic bladder cancer. American journal of clinical oncology, 2014, Volume: 37, Issue:2 Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Deoxycytidine; Disease-Free Survival; Drug Administration Schedule; Female; Gemcitabine; Humans; Irinotecan; Male; Middle Aged; Nausea; Neutropenia; Treatment Outcome; Urinary Bladder Neoplasms	2014

Other Studies

38 other study(ies) available for camptothecin and Bladder Cancer

Article	Year
Biological profile of new apoptotic agents based on 2,4-pyrido[2,3-d]pyrimidine derivatives. Bioorganic & medicinal chemistry, 2007, Feb-15, Volume: 15, Issue:4 Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; Dose-Response Relationship, Drug; Humans; Pyrimidines; Signal Transduction; Urinary Bladder Neoplasms	2007
AMPK-mTOR-ULK1 axis activation-dependent autophagy promotes hydroxycamptothecin-induced apoptosis in human bladder cancer cells. Journal of cellular physiology, 2020, Volume: 235, Issue:5 Topics: Adenylate Kinase; Apoptosis; Autophagy; Autophagy-Related Protein-1 Homolog; Benzimidazoles; Camptothecin; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Molecular Structure; TOR Serine-Threonine Kinases; Urinary Bladder Neoplasms	2020
Modeling biological and genetic diversity in upper tract urothelial carcinoma with patient derived xenografts. Nature communications, 2020, 04-24, Volume: 11, Issue:1 Topics: Aged; Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biopsy; Camptothecin; Carcinoma, Transitional Cell; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genetic Variation; High-Throughput Nucleotide Sequencing; Humans; Immunoconjugates; Interleukin Receptor Common gamma Subunit; Male; Mice; Mice, Inbred NOD; Mice, SCID; Middle Aged; Mutation; Neoplasm Metastasis; Neoplasm Transplantation; Phenotype; Precision Medicine; Prospective Studies; Quinolines; Retrospective Studies; Sequence Analysis, RNA; Trastuzumab; Urinary Bladder Neoplasms; Urothelium	2020
2020 ASCO Annual Meeting. The Lancet. Haematology, 2020, Volume: 7, Issue:7 Topics: Anaplastic Lymphoma Kinase; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Brain Neoplasms; Camptothecin; Cholangiocarcinoma; Clinical Trials as Topic; Colorectal Neoplasms; Female; Humans; Immunoconjugates; Neoplasms; Ovarian Neoplasms; Protein Kinase Inhibitors; Societies, Medical; Trastuzumab; Urinary Bladder Neoplasms	2020
HCPT-peptide prodrug with tumor microenvironment -responsive morphology transformable characteristic for boosted bladder tumor chemotherapy. Journal of controlled release : official journal of the Controlled Release Society, 2021, 02-10, Volume: 330 Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Drug Carriers; Humans; Peptides; Prodrugs; Tumor Microenvironment; Urinary Bladder Neoplasms	2021
Utilization of systemic therapy for treatment of advanced urothelial carcinoma: Lessons from real world experience. Cancer treatment and research communications, 2021, Volume: 27 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Carcinoma, Transitional Cell; Chemotherapy, Adjuvant; Cisplatin; Cystectomy; Disease-Free Survival; Drug Administration Schedule; Evidence-Based Medicine; Humans; Immunoconjugates; Medical Oncology; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Practice Patterns, Physicians'; Randomized Controlled Trials as Topic; Urinary Bladder Neoplasms	2021
Phthalazino[1,2-b]quinazolinones as p53 Activators: Cell Cycle Arrest, Apoptotic Response and Bak-Bcl-xl Complex Reorganization in Bladder Cancer Cells. Journal of medicinal chemistry, 2017, 08-24, Volume: 60, Issue:16 Topics: Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Camptothecin; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; Humans; Phthalazines; Quinazolinones; S Phase Cell Cycle Checkpoints; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms	2017
Synergistic antitumour effects of triptolide plus 10-hydroxycamptothecin onbladder cancer. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 115 Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diterpenes; Drug Synergism; Epoxy Compounds; Mice, Inbred BALB C; Mice, Nude; Phenanthrenes; Reactive Oxygen Species; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays	2019
Therapeutic enhancement of S-1 with CPT-11 through down-regulation of thymidylate synthase in bladder cancer. Cancer medicine, 2013, Volume: 2, Issue:4 Topics: Animals; Camptothecin; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drug Combinations; Drug Resistance, Neoplasm; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Mice; Mice, Nude; Oxonic Acid; RNA Interference; RNA, Small Interfering; Tegafur; Thymidylate Synthase; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays	2013
Human Neural Stem Cells Overexpressing a Carboxylesterase Inhibit Bladder Tumor Growth. Molecular cancer therapeutics, 2016, Volume: 15, Issue:6 Topics: Animals; Camptothecin; Carboxylesterase; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Irinotecan; Mice; Neoplasm Transplantation; Neural Stem Cells; Prodrugs; Urinary Bladder Neoplasms	2016
Positively charged polypeptide nanogel enhances mucoadhesion and penetrability of 10-hydroxycamptothecin in orthotopic bladder carcinoma. Journal of controlled release : official journal of the Controlled Release Society, 2017, 08-10, Volume: 259 Topics: Adhesiveness; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Carriers; Drug Liberation; Gels; Humans; Male; Mice, Inbred BALB C; Mucous Membrane; Nanostructures; Peptides; Tissue Distribution; Urinary Bladder Neoplasms	2017
A case of relapsing secondary bladder adenocarcinoma after right colonic cancer. Nature clinical practice. Urology, 2008, Volume: 5, Issue:7 Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cecal Neoplasms; Cetuximab; Chemotherapy, Adjuvant; Colectomy; Female; Fluorouracil; Humans; Immunohistochemistry; Irinotecan; Leucovorin; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Organoplatinum Compounds; Quinazolines; Retroperitoneal Neoplasms; Sacrum; Thiophenes; Tomography, X-Ray Computed; Urinary Bladder Neoplasms	2008
[Prophylactic effect of inductive intravesical instillation of Bacillus Calmette-Guerin on postoperative recurrence of bladder cancer]. Ai zheng = Aizheng = Chinese journal of cancer, 2008, Volume: 27, Issue:11 Topics: Adjuvants, Immunologic; Administration, Intravesical; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; BCG Vaccine; Camptothecin; Carcinoma, Transitional Cell; Cystectomy; Female; Fever; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Urinary Bladder Neoplasms	2008
Local enzymatic hydrolysis of an endogenously generated metabolite can enhance CPT-11 anticancer efficacy. Molecular cancer therapeutics, 2009, Volume: 8, Issue:4 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carboxylesterase; Cell Proliferation; Female; Flow Cytometry; Glucuronates; Glucuronidase; Humans; Irinotecan; Mice; Mice, SCID; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Urinary Bladder Neoplasms	2009
MONCPT exerts anti-cancer activities via inducing G2/M arrest and apoptosis in human bladder cancer. Die Pharmazie, 2009, Volume: 64, Issue:12 Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Camptothecin; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; G2 Phase; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Up-Regulation; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays	2009
Mapping of the UGT1A locus identifies an uncommon coding variant that affects mRNA expression and protects from bladder cancer. Human molecular genetics, 2012, Apr-15, Volume: 21, Issue:8 Topics: Camptothecin; Carcinogens; Case-Control Studies; Chromosome Mapping; Genetic Predisposition to Disease; Genome-Wide Association Study; Glucuronosyltransferase; Humans; Irinotecan; Liver; Phenotype; Polymorphism, Single Nucleotide; Protein Isoforms; Risk Factors; RNA, Messenger; Urinary Bladder; Urinary Bladder Neoplasms	2012
Increased expression of DNA repair gene XPF enhances resistance to hydroxycamptothecin in bladder cancer. Medical science monitor : international medical journal of experimental and clinical research, 2012, Volume: 18, Issue:4 Topics: Apoptosis; Camptothecin; Caspases; Cell Line, Tumor; DNA Repair; DNA-Binding Proteins; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Neoplasm; Humans; RNA, Messenger; RNA, Small Interfering; Urinary Bladder Neoplasms	2012
Genistein sensitizes bladder cancer cells to HCPT treatment in vitro and in vivo via ATM/NF-κB/IKK pathway-induced apoptosis. PloS one, 2013, Volume: 8, Issue:1 Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Camptothecin; Cell Cycle Proteins; Cell Line, Tumor; DNA Fragmentation; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Genistein; Humans; I-kappa B Kinase; Mice; Mice, Nude; NF-kappa B; Protein Serine-Threonine Kinases; Signal Transduction; Topoisomerase I Inhibitors; Tumor Suppressor Proteins; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays	2013
Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation. The Journal of biological chemistry, 2003, Jun-06, Volume: 278, Issue:23 Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Binding Sites; Camptothecin; Carrier Proteins; Caspase 7; Caspases; Cell Membrane; Cricetinae; Doxorubicin; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Precursors; Etoposide; G1 Phase; Gene Expression; Heat-Shock Proteins; Humans; Leukemia; Molecular Chaperones; Protein Structure, Tertiary; Subcellular Fractions; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transfection; Tumor Cells, Cultured; Urinary Bladder Neoplasms	2003
Cellular basis of antiproliferative and antitumor activity of the novel camptothecin derivative, gimatecan, in bladder carcinoma models. Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:2 Topics: Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Camptothecin; Disease Models, Animal; DNA Topoisomerases, Type I; Down-Regulation; Female; Humans; Mice; Mice, Nude; Protease Inhibitors; Pyrazines; RNA, Messenger; S Phase; Topoisomerase I Inhibitors; Topotecan; Transplantation, Heterologous; Tumor Cells, Cultured; Urinary Bladder Neoplasms	2005
[A young patient with invasive small cell carcinoma of the urinary bladder: a case report]. Hinyokika kiyo. Acta urologica Japonica, 2005, Volume: 51, Issue:4 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Cystoscopy; Drug Administration Schedule; Female; Humans; Hysterectomy; Irinotecan; Neoplasm Invasiveness; Urinary Bladder Neoplasms	2005
Protocol consisting of cisplatin, etoposide and irinotecan induced complete pathological remission of primary small cell carcinoma of the bladder. International journal of urology : official journal of the Japanese Urological Association, 2006, Volume: 13, Issue:9 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Etoposide; Humans; Irinotecan; Male; Neoadjuvant Therapy; Remission Induction; Urinary Bladder Neoplasms	2006
[A case of recurrent colon cancer with urinary bladder, para-aortic lymph nodes, and spleen metastases successfully treated with CPT-11]. Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:1 Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Phytogenic; Aorta; Camptothecin; Combined Modality Therapy; Drug Administration Schedule; Female; Humans; Irinotecan; Lymph Nodes; Lymphatic Metastasis; Neoplasm Invasiveness; Quality of Life; Remission Induction; Sigmoid Neoplasms; Splenic Neoplasms; Urinary Bladder Neoplasms	2007
[Small cell carcinoma of the urinary bladder treated with neo-adjuvant cp chemotherapy (CPT-11 and CDDP): a case report]. Hinyokika kiyo. Acta urologica Japonica, 2007, Volume: 53, Issue:2 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Cisplatin; Drug Administration Schedule; Humans; Irinotecan; Male; Urinary Bladder Neoplasms	2007
[Lethal effect of adenovirus-mediated HSV-TK gene in combination with hydroxycamptothecin on human bladder cancer in vitro]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2007, Volume: 27, Issue:4 Topics: Adenoviridae; Apoptosis; Camptothecin; Cell Line, Tumor; Ganciclovir; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; Humans; Thymidine Kinase; Transfection; Urinary Bladder Neoplasms	2007
Bacillus Calmette-Guerin inhibits apoptosis in human urothelial carcinoma cell lines in response to cytotoxic injury. The Journal of urology, 2007, Volume: 178, Issue:5 Topics: Adjuvants, Immunologic; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; BCG Vaccine; Camptothecin; Carcinoma, Transitional Cell; Cell Line, Tumor; Cell Proliferation; Cross-Linking Reagents; DNA Fragmentation; DNA, Neoplasm; Humans; Mitomycin; Urinary Bladder Neoplasms	2007
Treatment of metastatic urachal carcinoma in an elderly woman. Nature clinical practice. Oncology, 2008, Volume: 5, Issue:1 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Signet Ring Cell; Combined Modality Therapy; Cystectomy; Diagnosis, Differential; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Lymph Node Excision; Neoplasm Recurrence, Local; Pelvic Neoplasms; Radiotherapy, Adjuvant; Urachus; Urinary Bladder Neoplasms	2008
Different fates of camptothecin-induced replication fork-associated double-strand DNA breaks in mammalian cells. Carcinogenesis, 1994, Volume: 15, Issue:5 Topics: Animals; Caffeine; Camptothecin; Cell Line; CHO Cells; Chromosome Aberrations; Cricetinae; DNA; DNA Damage; DNA Replication; DNA, Neoplasm; Humans; Mitosis; Sensitivity and Specificity; Skin; Skin Physiological Phenomena; Urinary Bladder Neoplasms	1994
Increased expression of DNA topoisomerase I gene and collateral sensitivity to camptothecin in human cisplatin-resistant bladder cancer cells. Cancer research, 1994, Jun-15, Volume: 54, Issue:12 Topics: Blotting, Northern; Camptothecin; Carcinoma, Transitional Cell; Cell Cycle; Cell Division; Cisplatin; DNA Topoisomerases, Type I; Drug Resistance; Drug Screening Assays, Antitumor; Gene Expression; Glutathione; Glutathione Transferase; Humans; Immunoblotting; Intracellular Fluid; RNA, Messenger; Tumor Cells, Cultured; Urinary Bladder Neoplasms	1994
Influence of low pH on cytotoxicity of paclitaxel, mitoxantrone and topotecan. British journal of cancer, 1997, Volume: 75, Issue:8 Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Cycle; Cell Survival; DNA, Neoplasm; Female; Humans; Hydrogen-Ion Concentration; Mammary Neoplasms, Experimental; Mice; Mitoxantrone; Paclitaxel; Topotecan; Tumor Cells, Cultured; Urinary Bladder Neoplasms	1997
Camptothecin analogues/cisplatin: an effective treatment of advanced bladder cancer in a preclinical in vivo model system. The Journal of urology, 1998, Volume: 160, Issue:1 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Screening Assays, Antitumor; Humans; Irinotecan; Mice; Mice, Inbred BALB C; Neoplasm Staging; Tumor Cells, Cultured; Urinary Bladder Neoplasms	1998
[10-Hydroxycamptothecin induces apoptosis in human T24 urinary bladder cancer cells]. Zhonghua yi xue za zhi, 1998, Volume: 78, Issue:4 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Cycle; Humans; Tumor Cells, Cultured; Urinary Bladder Neoplasms	1998
Pharmacological determinants of 9-aminocamptothecin cytotoxicity. Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:1 Topics: Antineoplastic Agents; Breast Neoplasms; Camptothecin; Cell Division; Colonic Neoplasms; Dose-Response Relationship, Drug; Humans; Tumor Cells, Cultured; Urinary Bladder Neoplasms	2001
[Clinical study on super-selective camptothecin microsphere's embolization of internal iliac artery for bladder carcinoma]. Zhonghua yi xue za zhi, 2000, Volume: 80, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Camptothecin; Embolization, Therapeutic; Humans; Iliac Artery; Male; Microspheres; Middle Aged; Urinary Bladder Neoplasms	2000
[Detection of apoptosis exposed to 10-hydroxycamptothecin in T24 human urinary bladder cancer cells]. Zhonghua wai ke za zhi [Chinese journal of surgery], 1999, Volume: 37, Issue:1 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Line, Tumor; Comet Assay; Flow Cytometry; Fluorescent Dyes; Hematoxylin; Humans; Staining and Labeling; Urinary Bladder Neoplasms	1999
Camptothecin instillation and local injection for prevention and treatment of urinary bladder tumors--a preliminary report. Chinese medical journal, 1979, Volume: 92, Issue:1 Topics: Adult; Aged; Camptothecin; Carcinoma in Situ; Carcinoma, Papillary; Female; Humans; Injections; Male; Middle Aged; Urinary Bladder Neoplasms	1979
The inhibition of cellular recovery in human tumour cells by inhibitors of topoisomerase. British journal of cancer, 1990, Volume: 62, Issue:3 Topics: Camptothecin; Cell Survival; DNA; DNA Repair; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Combinations; Etoposide; Humans; Radiation Tolerance; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Urinary Bladder Neoplasms	1990
Factors influencing the absorption of antineoplastic agents in intravesical instillation treatment of bladder tumors. An experimental and clinical study. Chinese medical journal, 1987, Volume: 100, Issue:2 Topics: Absorption; Administration, Intravesical; Adult; Aged; Animals; Camptothecin; Carcinoma, Transitional Cell; Female; Humans; Male; Middle Aged; Rabbits; Thiotepa; Urinary Bladder Neoplasms	1987