camptothecin has been researched along with Ataxia Telangiectasia in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y; Xiong, H; Yang, DQ | 1 |
| Cordell, HJ; Johnson, RT; Leonard, JC; Mullinger, AM; Schmidt, J | 1 |
| Cao, CX; Kohn, KW; Pommier, Y; Shao, RG; Wold, MS; Zhang, H | 1 |
| Piette, J; Piret, B; Schoonbroodt, S | 1 |
| Gotoh, E; Johnson, RT; Mullinger, AM; Ryan, AJ; Shiloh, Y; Squires, S; Ziv, Y | 1 |
| Bryant, PE; Johnson, MA; Jones, NJ | 1 |
| Boyer, JC; Estabrooks, LL; Kaufmann, WK; Wilson, SJ | 1 |
| Ganesh, AN; Thacker, J | 1 |
| Davies, SM; Harris, AL; Hickson, ID | 1 |
| Makinson, TA; Smith, PJ; Watson, JV | 1 |
10 other study(ies) available for camptothecin and Ataxia Telangiectasia
| Article | Year |
|---|---|
Functional switching of ATM: sensor of DNA damage in proliferating cells and mediator of Akt survival signal in post-mitotic human neuron-like cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Camptothecin; Cell Cycle Proteins; Cell Differentiation; Cell Line, Tumor; DNA Damage; DNA-Binding Proteins; Etoposide; Histones; Humans; Morpholines; Neuroblastoma; Neurons; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyrones; Signal Transduction; Topoisomerase Inhibitors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2012 |
Genome instability in ataxia telangiectasia (A-T) families: camptothecin-induced damage to replicating DNA discriminates between obligate A-T heterozygotes, A-T homozygotes and controls.
Topics: Ataxia Telangiectasia; Camptothecin; Cell Line; DNA Damage; DNA Repair; DNA Replication; Genomic Instability; Heterozygote; Homozygote; Humans; In Situ Hybridization, Fluorescence; In Vitro Techniques; Lymphocytes; Mutation | 2004 |
Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes.
Topics: Alkaloids; Androstadienes; Antigens, Nuclear; Ataxia Telangiectasia; Camptothecin; Cell Cycle; DNA Damage; DNA Helicases; DNA Repair; DNA Replication; DNA Topoisomerases, Type I; DNA-Activated Protein Kinase; DNA-Binding Proteins; Etoposide; Humans; Ku Autoantigen; Nuclear Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Replication Protein A; Staurosporine; Tumor Cells, Cultured; Wortmannin | 1999 |
The ATM protein is required for sustained activation of NF-kappaB following DNA damage.
Topics: Adolescent; Age Factors; Antineoplastic Agents, Phytogenic; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms; Camptothecin; Cell Cycle Proteins; Cells, Cultured; Child; Child, Preschool; DNA Damage; DNA-Activated Protein Kinase; DNA-Binding Proteins; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Glioblastoma; Humans; I-kappa B Proteins; Leupeptins; NF-kappa B; NF-KappaB Inhibitor alpha; Nuclear Proteins; Phosphoric Monoester Hydrolases; Protease Inhibitors; Protein Serine-Threonine Kinases; Proteins; Radiation Tolerance; Recombinant Fusion Proteins; Topoisomerase I Inhibitors; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 1999 |
Targeting double-strand breaks to replicating DNA identifies a subpathway of DSB repair that is defective in ataxia-telangiectasia cells.
Topics: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Camptothecin; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Survival; DNA Damage; DNA Repair; DNA Replication; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Protein Serine-Threonine Kinases; Proteins; Recombinant Proteins; Recombination, Genetic; Sister Chromatid Exchange; Topoisomerase I Inhibitors; Transfection; Tumor Suppressor Proteins | 1999 |
Isolation of camptothecin-sensitive chinese hamster cell mutants: phenotypic heterogeneity within the ataxia telangiectasia-like XRCC8 (irs2) complementation group.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Bleomycin; Camptothecin; Cell Cycle; Cell Cycle Proteins; Cell Line; Cricetinae; DNA Repair; DNA-Binding Proteins; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Doxorubicin; Enzyme Inhibitors; Etoposide; Gamma Rays; Genes, Dominant; Genetic Complementation Test; Mitomycin; Mutation; Nucleic Acid Synthesis Inhibitors; Phenotype; Protein Serine-Threonine Kinases; Streptonigrin; Tumor Suppressor Proteins | 2000 |
Inhibition of replicon initiation in human cells following stabilization of topoisomerase-DNA cleavable complexes.
Topics: Amsacrine; Ataxia Telangiectasia; Camptothecin; Cell Line; DNA; DNA Damage; DNA Replication; Drug Resistance; Humans; Kinetics; Replicon; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Xeroderma Pigmentosum | 1991 |
DNA-break repair, radioresistance of DNA synthesis, and camptothecin sensitivity in the radiation-sensitive irs mutants: comparisons to ataxia-telangiectasia cells.
Topics: Animals; Ataxia Telangiectasia; Camptothecin; Cell Line; Cell Line, Transformed; Cricetinae; Cricetulus; DNA; DNA Repair; DNA Replication; Humans; Mutation; Radiation Tolerance | 1990 |
Overproduction of topoisomerase II in an ataxia telangiectasia fibroblast cell line: comparison with a topoisomerase II-overproducing hamster cell mutant.
Topics: Amsacrine; Animals; Ataxia Telangiectasia; Blotting, Western; Camptothecin; Cell Line; Cell Survival; Cricetinae; DNA Replication; DNA Topoisomerases, Type II; Fibroblasts; Humans; Kinetics; Mutation | 1989 |
Enhanced sensitivity to camptothecin in ataxia-telangiectasia cells and its relationship with the expression of DNA topoisomerase I.
Topics: Ataxia Telangiectasia; Camptothecin; Cell Cycle; Cell Line; Cell Line, Transformed; Cell Survival; DNA Topoisomerases, Type I; Drug Screening Assays, Antitumor; Fibroblasts; Humans; In Vitro Techniques; Xeroderma Pigmentosum | 1989 |