camptothecin has been researched along with Alzheimer Disease in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hirao, N; Nose, Y; Saeki, K; Takasawa, R; Tanuma, S | 1 |
| Ahn, JH; Boo, JH; Jeon, GS; Kang, DE; Kim, C; Kim, KH; Kim, YE; Mook-Jung, I; Ryu, H; Song, H | 1 |
| Cotman, CW; Deng, G; Su, JH; Torp, R | 1 |
| Clarke, EE; Gervais, FG; Huang, J; LeBlanc, A; Nicholson, DW; Rigby, M; Robertson, GS; Roy, S; Ruffolo, SC; Shearman, MS; Smith, D; Thornberry, NA; Vaillancourt, JP; Van Der Ploeg, LH; Xanthoudakis, S; Xu, D; Zamboni, RJ; Zheng, H; Zhu, Y | 1 |
| Dodds, HM; Rivory, LP | 1 |
| Bondada, S; Culmsee, C; Mattson, MP | 1 |
| Johnson, GV; Mookherjee, P | 1 |
7 other study(ies) available for camptothecin and Alzheimer Disease
| Article | Year |
|---|---|
Amyloid precursor protein binding protein Fe65 is cleaved by caspases during DNA damage-induced apoptosis.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Apoptosis; Camptothecin; Caspases; Cell Line, Tumor; Cytotoxins; DNA Damage; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Humans; Nerve Tissue Proteins; Neuroblastoma; Neurons; Nuclear Proteins; Signal Transduction | 2011 |
Critical role of presenilin-dependent γ-secretase activity in DNA damage-induced promyelocytic leukemia protein expression and apoptosis.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Apoptosis; Brain; Camptothecin; Carbamates; Cell Line; Dipeptides; DNA Damage; Gene Expression; Gene Knockout Techniques; HEK293 Cells; Humans; Leukemia, Promyelocytic, Acute; Mice; Nuclear Proteins; Presenilins; Promyelocytic Leukemia Protein; RNA Interference; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Transcription Factors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Up-Regulation | 2013 |
GADD45 is induced in Alzheimer's disease, and protects against apoptosis in vitro.
Topics: Alzheimer Disease; Apoptosis; Brain; Camptothecin; Cell Death; Cell Line; DNA Fragmentation; Enzyme Inhibitors; GADD45 Proteins; Gene Expression; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Neurofibrillary Tangles; Neurons; Plasmids; Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Transfection | 1998 |
Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation.
Topics: Acute Disease; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Amyloidosis; Animals; Apoptosis; Aspartic Acid; Aspartic Acid Endopeptidases; Brain Diseases; Camptothecin; Caspase 3; Caspases; Cysteine Proteinase Inhibitors; Endopeptidases; Enzyme Inhibitors; Enzyme Precursors; Excitatory Amino Acid Agonists; Hippocampus; Humans; In Situ Nick-End Labeling; Kainic Acid; Leukemia, Erythroblastic, Acute; Male; Mice; Mice, Inbred C57BL; Mutation; Neurons; Oligopeptides; Rabbits; Rats; Rats, Wistar; Sweden; Tumor Cells, Cultured | 1999 |
The mechanism for the inhibition of acetylcholinesterases by irinotecan (CPT-11).
Topics: Acetylcholinesterase; Acylation; Alzheimer Disease; Binding, Competitive; Butyrylcholinesterase; Camptothecin; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Erythrocytes; Humans; Hydrolysis; Irinotecan; Kinetics; Neostigmine; Propidium; Substrate Specificity; Tacrine | 1999 |
Hippocampal neurons of mice deficient in DNA-dependent protein kinase exhibit increased vulnerability to DNA damage, oxidative stress and excitotoxicity.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Camptothecin; DNA Damage; DNA-Activated Protein Kinase; DNA-Binding Proteins; Enzyme Inhibitors; Epilepsy; Etoposide; Glutamic Acid; Hippocampus; Mice; Mice, SCID; Neurons; Neurotoxins; Nucleic Acid Synthesis Inhibitors; Oxidative Stress; Protein Serine-Threonine Kinases; Topoisomerase I Inhibitors | 2001 |
Tau phosphorylation during apoptosis of human SH-SY5Y neuroblastoma cells.
Topics: Alzheimer Disease; Antibodies; Apoptosis; Brain; Camptothecin; Caspase 3; Caspase Inhibitors; Caspases; Cell Survival; Cells, Cultured; Cyclin-Dependent Kinases; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; L-Lactate Dehydrogenase; Microtubules; Neuroblastoma; Neurons; Phosphorylation; Protein Kinases; tau Proteins; Tumor Suppressor Protein p53 | 2001 |