camptothecin has been researched along with Acute Disease in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (50.00) | 18.2507 |
| 2000's | 7 (31.82) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Hara, T; Hasegawa, J; Hata, T; Imamoto, H; Kim, Y; Okano, M; Takayama, O; Tanizaki, K | 1 |
| Amatu, A; Bernardo, G; Montagna, B; Pagella, C; Poggi, G; Pozzi, E; Quaretti, P; Sottotetti, F; Tagliaferri, B | 1 |
| Furushima, K; Ishihara, T; Katou, Y; Tanai, C; Tanaka, Y; Usui, K | 1 |
| Hashimoto, M; Hiraike, M; Honda, S; Misumi, N; Nabeshima, A; Nawata, F; Takase, I; Tanigawa, K | 1 |
| Cortes, JE; De Jager, RL; Faderl, S; Garcia-Manero, G; Giles, FJ; Jeha, S; Kantarjian, HM; Thomas, DA | 1 |
| Beatrix, O; Dumortier, J; Lapalus, MG; Lombard-Bohas, C; Scoazec, JY; Villarejo, J; Vochelle, V | 1 |
| Albitar, M; Barrett, E; Cortes, JE; Garcia-Manero, G; Giles, FJ; Hamilton, M; Kantarjian, HM; Tallman, MS; Thomas, DA; Verstovsek, S; Wierda, WG | 1 |
| Adams, DJ; Colvin, OM; Flowers, JL; Rizzieri, DA; Shanks, RH | 1 |
| Baer, MR; Ford, LA; Greco, WR; Minderman, H; O'Loughlin, KL; Pendyala, L; Smith, PF; Sweeney, KG; Wetzler, M | 1 |
| Chu, KW; Epstein, RJ; Liang, RH; Mok, MY; Yau, TC | 1 |
| Fujimori, A; Harker, WG; Kapoor, R; Pommier, Y; Slade, DL | 1 |
| Adjei, A; Burke, PJ; Cheng, YC; Donehower, RC; Gore, SD; Grochow, LB; Jones, RJ; Kaufmann, SH; Rowinsky, EK | 1 |
| Ariyoshi, Y; Ogawa, M | 1 |
| Beran, M; Cazenave, L; Ellis, A; Kantarjian, HM; Keating, MJ; Koller, C; O'Brien, S; Plunkett, W; Rios, MB; Zwelling, L | 1 |
| Aboud, M; Aflalo, E; Benharroch, D; Chechelnitsky, G; Priel, E; Segal, S | 1 |
| Crumpacker, CS; Dezube, BJ; Li, CJ; Pardee, AB; Zhang, LJ | 1 |
| Baker, SD; Evans, WE; Furman, WL; Pratt, CB; Rivera, GK; Stewart, CF | 1 |
| Fujii, T; Hirata, K; Kanazawa, H; Katsumoto, E; Kudoh, S; Kurihara, N; Ohtsuka, T; Okishio, K; Shoji, S; Yoshikawa, J | 1 |
| Beran, M; Jeha, S; Kantarjian, H; O'Brien, S; Vitek, L | 1 |
| Clarke, EE; Gervais, FG; Huang, J; LeBlanc, A; Nicholson, DW; Rigby, M; Robertson, GS; Roy, S; Ruffolo, SC; Shearman, MS; Smith, D; Thornberry, NA; Vaillancourt, JP; Van Der Ploeg, LH; Xanthoudakis, S; Xu, D; Zamboni, RJ; Zheng, H; Zhu, Y | 1 |
| Ahmed, M; Fraser, NW; Lock, M; Miller, CG | 1 |
| Donehower, RC; Grochow, LB; Hendricks, CB; Kaufmann, SH; Rowinsky, EK | 1 |
1 review(s) available for camptothecin and Acute Disease
| Article | Year |
|---|---|
[Clinical trials of new antitumor drugs in hematopoietic malignancies].
Topics: Acute Disease; Antineoplastic Agents, Phytogenic; Camptothecin; Clinical Trials as Topic; Doxorubicin; Ethics, Medical; Humans; Idarubicin; Irinotecan; Leukemia; Lymphoma | 1994 |
6 trial(s) available for camptothecin and Acute Disease
| Article | Year |
|---|---|
Phase I and pharmacokinetic study of DX-8951f (exatecan mesylate), a hexacyclic camptothecin, on a daily-times-five schedule in patients with advanced leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy; Stomatitis; Topoisomerase I Inhibitors | 2002 |
Phase I and pharmacokinetic study of a low-clearance, unilamellar liposomal formulation of lurtotecan, a topoisomerase 1 inhibitor, in patients with advanced leukemia.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Area Under Curve; Camptothecin; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid; Male; Metabolic Clearance Rate; Middle Aged; Mouth Mucosa; Topoisomerase I Inhibitors; Treatment Outcome | 2004 |
Sequential administration of irinotecan and cytarabine in the treatment of relapsed and refractory acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cytarabine; DNA Damage; DNA Topoisomerases, Type I; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Synergism; Female; HL-60 Cells; Humans; Irinotecan; Leukemia, Myeloid; Male; Middle Aged; Recurrence | 2006 |
Phase I and pharmacodynamic study of the topoisomerase I-inhibitor topotecan in patients with refractory acute leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Camptothecin; Daunorubicin; Drug Administration Schedule; Drug Resistance, Multiple; Female; Follow-Up Studies; Humans; Immunohistochemistry; Leukemia; Male; Middle Aged; Mouth Mucosa; Quinidine; Remission Induction; Stomatitis; Topoisomerase I Inhibitors; Topotecan; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1994 |
Phase I study of Topotecan, a new topoisomerase I inhibitor, in patients with refractory or relapsed acute leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Camptothecin; DNA; DNA Topoisomerases, Type I; Drug Administration Schedule; Female; Humans; Irinotecan; Leukemia; Male; Middle Aged; Topoisomerase I Inhibitors; Topotecan | 1993 |
Escalating systemic exposure of continuous infusion topotecan in children with recurrent acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Camptothecin; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Infant; Infusions, Intravenous; Leukemia; Male; Metabolic Clearance Rate; Recurrence; Topotecan | 1996 |
15 other study(ies) available for camptothecin and Acute Disease
| Article | Year |
|---|---|
[A Case of Recurrent Rectal Cancer with Acute Lower Extremity Arterial Occlusion during Treatment with Bevacizumab].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Male; Neoplasm Recurrence, Local; Rectal Neoplasms | 2023 |
Acute thrombocytopenia: an unusual complication occurring after drug-eluting microspheres transcatheter hepatic chemoembolization.
Topics: Acute Disease; Adenocarcinoma; Antineoplastic Agents; Camptothecin; Chemoembolization, Therapeutic; Colonic Neoplasms; Follow-Up Studies; Humans; Irinotecan; Leukocyte Count; Liver Neoplasms; Male; Microspheres; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Platelet Count; Sigmoid Neoplasms; Thrombocytopenia | 2011 |
Interstitial lung disease during chemotherapy combined with oxaliplatin and/or bevacizumab in advanced colorectal cancer patients.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Alveolitis, Extrinsic Allergic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Disease-Free Survival; Fluorouracil; Humans; Japan; Leucovorin; Lung Diseases, Interstitial; Male; Medical Records Systems, Computerized; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Pulmonary Fibrosis; Retrospective Studies; Severity of Illness Index; Smoking; Tomography, X-Ray Computed | 2011 |
[Protective effects of d-chlorpheniramine maleate pre-treatment against acute side effects of Irinotecan(CPT- 11)].
Topics: Acute Disease; Antineoplastic Agents, Phytogenic; Camptothecin; Chlorpheniramine; Female; Humans; Irinotecan; Male; Middle Aged; Neoplasms | 2011 |
[Severe acute cytomegalovirus colitis after administration of irinotecan and raltitrexed chemotherapy].
Topics: Acute Disease; Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Camptothecin; Colitis; Cytomegalovirus Infections; Ganciclovir; Humans; Immunocompromised Host; Irinotecan; Male; Quinazolines; Rectal Neoplasms; Sigmoid Neoplasms; Thiophenes | 2003 |
Preclinical evaluation of gemcitabine combination regimens for application in acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Agents; Apoptosis; Camptothecin; Caspase 3; Caspase 7; Caspases; Cell Cycle; Chlorambucil; Deoxycytidine; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation, Preclinical; Drug Interactions; Enzyme Activation; Flow Cytometry; Gemcitabine; Humans; Irinotecan; Leukemia, Myeloid; Mitoxantrone; Paclitaxel; U937 Cells; Vidarabine | 2005 |
Acute presentation of rheumatoid arthritis following cancer chemotherapy using the topoisomerase I inhibitor irinotecan.
Topics: Acute Disease; Antineoplastic Agents, Phytogenic; Arthritis, Rheumatoid; Camptothecin; Colorectal Neoplasms; Humans; Irinotecan; Male; Middle Aged; Topoisomerase I Inhibitors | 2005 |
Altered topoisomerase I expression in two subclones of human CEM leukemia selected for resistance to camptothecin.
Topics: Acute Disease; Base Sequence; Camptothecin; Catalysis; DNA Damage; DNA Topoisomerases, Type I; DNA, Neoplasm; Drug Resistance; Humans; Leukemia, Experimental; Leukemia, T-Cell; Molecular Sequence Data; Neoplasm Proteins; RNA, Messenger; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1995 |
Inhibition of retrovirus-induced disease in mice by camptothecin.
Topics: 3T3 Cells; Acute Disease; Animals; Animals, Newborn; Camptothecin; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Lymphoma; Mice; Mice, Inbred BALB C; Moloney murine leukemia virus; Neoplasms, Experimental; Retroviridae Infections; Spleen; Spleen Focus-Forming Viruses; Virus Replication | 1993 |
Three inhibitors of type 1 human immunodeficiency virus long terminal repeat-directed gene expression and virus replication.
Topics: Acute Disease; Antiviral Agents; Camptothecin; Cells, Cultured; Chronic Disease; Curcumin; Gene Expression Regulation, Viral; HIV Infections; HIV Long Terminal Repeat; HIV-1; In Vitro Techniques; Naphthoquinones; RNA, Viral; Topotecan; Virus Replication | 1993 |
[Small-cell lung cancer and subacute sensory neuropathy in a patient positive for the anti-Hu antigen].
Topics: Acute Disease; Antibodies, Anti-Idiotypic; Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Biomarkers, Tumor; Camptothecin; Carcinoma, Small Cell; Cisplatin; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Peripheral Nervous System Diseases | 1996 |
Activity of oral and intravenous 9-aminocamptothecin in SCID mice engrafted with human leukemia.
Topics: Acute Disease; Administration, Oral; Animals; Camptothecin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; HLA-DQ alpha-Chains; HLA-DQ Antigens; Humans; Injections, Intravenous; Leukemia, Experimental; Leukemia, Myeloid; Mice; Mice, SCID; Neoplasm Transplantation; Survival Rate | 1998 |
Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation.
Topics: Acute Disease; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Amyloidosis; Animals; Apoptosis; Aspartic Acid; Aspartic Acid Endopeptidases; Brain Diseases; Camptothecin; Caspase 3; Caspases; Cysteine Proteinase Inhibitors; Endopeptidases; Enzyme Inhibitors; Enzyme Precursors; Excitatory Amino Acid Agonists; Hippocampus; Humans; In Situ Nick-End Labeling; Kainic Acid; Leukemia, Erythroblastic, Acute; Male; Mice; Mice, Inbred C57BL; Mutation; Neurons; Oligopeptides; Rabbits; Rats; Rats, Wistar; Sweden; Tumor Cells, Cultured | 1999 |
Regions of the herpes simplex virus type 1 latency-associated transcript that protect cells from apoptosis in vitro and protect neuronal cells in vivo.
Topics: 5' Untranslated Regions; Acute Disease; Animals; Apoptosis; Camptothecin; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Line; DNA Fragmentation; Exons; fas Receptor; HeLa Cells; Herpes Simplex; Herpesvirus 1, Human; Humans; Introns; Mice; Neurons; Promoter Regions, Genetic; RNA, Viral; Sequence Deletion; Transcription, Genetic; Trigeminal Ganglion; Virus Activation; Virus Latency | 2002 |
Effect of P-glycoprotein expression on the accumulation and cytotoxicity of topotecan (SK&F 104864), a new camptothecin analogue.
Topics: Acute Disease; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Camptothecin; CHO Cells; Cricetinae; DNA Topoisomerases, Type I; DNA, Neoplasm; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Flow Cytometry; Leukemia; Membrane Glycoproteins; Quinidine; Topotecan; Tumor Cells, Cultured | 1992 |