Page last updated: 2024-10-24

camostat and Glomerulonephritis

camostat has been researched along with Glomerulonephritis in 3 studies

camostat : A benzoate ester resulting from the formal condensation of the carboxy group of 4-guanidinobenzoic acid with the hydroxy group of 2-(dimethylamino)-2-oxoethyl (4-hydroxyphenyl)acetate. It is a potent inhibitor of the human transmembrane protease serine 2 (TMPRSS2) and its mesylate salt is currently under investigation for its effectiveness in COVID-19 patients.

Glomerulonephritis: Inflammation of the renal glomeruli (KIDNEY GLOMERULUS) that can be classified by the type of glomerular injuries including antibody deposition, complement activation, cellular proliferation, and glomerulosclerosis. These structural and functional abnormalities usually lead to HEMATURIA; PROTEINURIA; HYPERTENSION; and RENAL INSUFFICIENCY.

Research Excerpts

ExcerptRelevanceReference
"The effects of camostat mesilate (CM), a derivative of gabexate mesilate developed for oral use, on primary glomerulonephritis (GN) and chance hematuria and/or proteinuria were evaluated."9.11Effect of oral camostat mesilate on hematuria and/or proteinuria in children. ( Asami, T; Tomisawa, S; Uchiyama, M, 2004)
"Camostat mesilate, a developed derivative of gabexate mesilate for oral use, was administered in a daily dose of 600 mg for 4 weeks to 17 patients with heavy proteinuria due to various nephropathies."7.67Effect of camostat mesilate on heavy proteinuria in various nephropathies. ( Futaki, G; Hotta, O; Kurosawa, K; Matsubara, M; Suzuki, K; Taguma, Y, 1989)
"The effects of camostat mesilate (CM), a derivative of gabexate mesilate developed for oral use, on primary glomerulonephritis (GN) and chance hematuria and/or proteinuria were evaluated."5.11Effect of oral camostat mesilate on hematuria and/or proteinuria in children. ( Asami, T; Tomisawa, S; Uchiyama, M, 2004)
"Effect of serine protease inhibitor Camostat Mesilate (Foipan) on primary glomerulonephritis and it's mechanism were evaluated."3.68[Effect of protease inhibitor on primary glomerulonephritis and the mechanism of the effect]. ( Fukushima, M; Haramoto, T; Kumagai, I; Makino, H; Murakami, K; Ogura, T; Onbe, T; Ota, Z; Wada, J, 1991)
"Camostat mesilate, a developed derivative of gabexate mesilate for oral use, was administered in a daily dose of 600 mg for 4 weeks to 17 patients with heavy proteinuria due to various nephropathies."3.67Effect of camostat mesilate on heavy proteinuria in various nephropathies. ( Futaki, G; Hotta, O; Kurosawa, K; Matsubara, M; Suzuki, K; Taguma, Y, 1989)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Asami, T1
Tomisawa, S1
Uchiyama, M1
Onbe, T1
Makino, H1
Haramoto, T1
Wada, J1
Ogura, T1
Kumagai, I1
Murakami, K1
Fukushima, M1
Ota, Z1
Matsubara, M1
Taguma, Y1
Kurosawa, K1
Hotta, O1
Suzuki, K1
Futaki, G1

Trials

1 trial available for camostat and Glomerulonephritis

ArticleYear
Effect of oral camostat mesilate on hematuria and/or proteinuria in children.
    Pediatric nephrology (Berlin, Germany), 2004, Volume: 19, Issue:3

    Topics: Administration, Oral; Adolescent; Biopsy; Child; Child, Preschool; Esters; Female; Follow-Up Studies

2004

Other Studies

2 other studies available for camostat and Glomerulonephritis

ArticleYear
[Effect of protease inhibitor on primary glomerulonephritis and the mechanism of the effect].
    Nihon Jinzo Gakkai shi, 1991, Volume: 33, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Urea Nitrogen; Complement System Proteins; Creatin

1991
Effect of camostat mesilate on heavy proteinuria in various nephropathies.
    Clinical nephrology, 1989, Volume: 32, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Esters; Female; Gabexate; Glomerulonephritis; Glycosu

1989