Page last updated: 2024-10-24
camostat and Carcinoma, Squamous Cell
camostat has been researched along with Carcinoma, Squamous Cell in 7 studies
camostat : A benzoate ester resulting from the formal condensation of the carboxy group of 4-guanidinobenzoic acid with the hydroxy group of 2-(dimethylamino)-2-oxoethyl (4-hydroxyphenyl)acetate. It is a potent inhibitor of the human transmembrane protease serine 2 (TMPRSS2) and its mesylate salt is currently under investigation for its effectiveness in COVID-19 patients.
Carcinoma, Squamous Cell: A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|
| " This drug at a dosage of 10 mg/kg or 20 mg/kg was administered by ip injection to 20 mice each harboring a solitary tumor twice daily for 10 weeks." | 1.26 | Inhibition of growth of 3-methylcholanthrene-induced mouse skin tumor by protease inhibitor [N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate. ( Ohkoshi, M, 1981) |
Research
Studies (7)
| Timeframe | Studies, this research(%) | All Research% |
|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
Authors
| Authors | Studies |
|---|
| Sun, G | 1 |
| Sui, Y | 1 |
| Zhou, Y | 1 |
| Ya, J | 1 |
| Yuan, C | 1 |
| Jiang, L | 1 |
| Huang, M | 1 |
| Ohkoshi, M | 6 |
| Fujii, S | 3 |
| Oka, T | 1 |
Reviews
1 review available for camostat and Carcinoma, Squamous Cell
Other Studies
6 other studies available for camostat and Carcinoma, Squamous Cell
| Article | Year |
|---|
Structural Basis of Covalent Inhibitory Mechanism of TMPRSS2-Related Serine Proteases by Camostat.Journal of virology, 2021, 09-09, Volume: 95, Issue:19
Topics: Antiviral Agents; Carcinoma, Squamous Cell; COVID-19; COVID-19 Drug Treatment; Esters; Guanidines; H | 2021 |
Effect of a protease inhibitor [N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate on the growth of mouse skin carcinoma in the rapid growing stage.The Journal of dermatology, 1984, Volume: 11, Issue:1
Topics: Administration, Oral; Animals; Carcinoma, Squamous Cell; Cell Division; Esters; Female; Gabexate; Gu | 1984 |
Effect of the synthetic protease inhibitor [N,N-dimethylcarbamoyl-methyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate on carcinogenesis by 3-methylcholanthrene in mouse skin.Journal of the National Cancer Institute, 1983, Volume: 71, Issue:5
Topics: Animals; Carcinoma, Squamous Cell; Diet; Esters; Female; Gabexate; Guanidines; Methylcholanthrene; M | 1983 |
Clinical experience with a protease inhibitor [N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate for prevention of recurrence of carcinoma of the mouth and in treatment of terminal carcinoma.Journal of maxillofacial surgery, 1984, Volume: 12, Issue:4
Topics: Adult; Carcinoma, Squamous Cell; Esters; Evaluation Studies as Topic; Female; Gabexate; Guanidines; | 1984 |
Effect of oral administration of protease inhibitor [N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate on the growth of 3-methylcholanthrene-induced carcinoma in mice.Gan, 1982, Volume: 73, Issue:1
Topics: Animals; Carcinoma, Squamous Cell; Cell Division; Esters; Female; Gabexate; Guanidines; Methylcholan | 1982 |
Inhibition of growth of 3-methylcholanthrene-induced mouse skin tumor by protease inhibitor [N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate.Gan, 1981, Volume: 72, Issue:6
Topics: Animals; Body Weight; Carcinoma, Squamous Cell; Cell Division; Drug Evaluation, Preclinical; Esters; | 1981 |