camostat has been researched along with Blood Pressure, High in 4 studies
camostat : A benzoate ester resulting from the formal condensation of the carboxy group of 4-guanidinobenzoic acid with the hydroxy group of 2-(dimethylamino)-2-oxoethyl (4-hydroxyphenyl)acetate. It is a potent inhibitor of the human transmembrane protease serine 2 (TMPRSS2) and its mesylate salt is currently under investigation for its effectiveness in COVID-19 patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We previously demonstrated that a high-salt (HS) diet provoked hypertension and proteinuria in Dahl salt-sensitive (DS) rats, accompanied by γENaC activation, which were attenuated by camostat mesilate (CM), an SP inhibitor." | 8.31 | A Serine Protease Inhibitor, Camostat Mesilate, Suppresses Urinary Plasmin Activity and Alleviates Hypertension and Podocyte Injury in Dahl Salt-Sensitive Rats. ( Adachi, M; Deng, Q; Iwata, Y; Izumi, Y; Kakizoe, Y; Kuwabara, T; Miyasato, Y; Mukoyama, M; Nagayoshi, Y; Nakagawa, M; Nakagawa, T; Narita, Y; Nishiguchi, K, 2023) |
| " Previously, we reported that a synthetic serine protease inhibitor, camostat mesilate (CM), mitigated hypertension and proteinuria in rodent disease models." | 8.02 | A serine protease inhibitor camostat mesilate prevents podocyte apoptosis and attenuates podocyte injury in metabolic syndrome model rats. ( Adachi, M; Deng, Q; Hayata, M; Iwata, Y; Izumi, Y; Kakizoe, Y; Kitamura, K; Kuwabara, T; Miyasato, Y; Miyoshi, T; Mizumoto, T; Morinaga, J; Mukoyama, M; Nakagawa, T; Sakai, Y; Tomita, K; Uchimura, K, 2021) |
| "Treatment with camostat mesilate or FOY-251 decreased equivalent current (Ieq) in M-1 cells in a dose-dependent manner and inhibited the protease activity of prostasin in vitro." | 5.35 | Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension. ( Adachi, M; Kakizoe, Y; Kitamura, K; Ko, T; Maekawa, A; Miyoshi, T; Shiraishi, N; Tomita, K; Wakida, N, 2009) |
| " We previously demonstrated that a high-salt (HS) diet provoked hypertension and proteinuria in Dahl salt-sensitive (DS) rats, accompanied by γENaC activation, which were attenuated by camostat mesilate (CM), an SP inhibitor." | 4.31 | A Serine Protease Inhibitor, Camostat Mesilate, Suppresses Urinary Plasmin Activity and Alleviates Hypertension and Podocyte Injury in Dahl Salt-Sensitive Rats. ( Adachi, M; Deng, Q; Iwata, Y; Izumi, Y; Kakizoe, Y; Kuwabara, T; Miyasato, Y; Mukoyama, M; Nagayoshi, Y; Nakagawa, M; Nakagawa, T; Narita, Y; Nishiguchi, K, 2023) |
| " Previously, we reported that a synthetic serine protease inhibitor, camostat mesilate (CM), mitigated hypertension and proteinuria in rodent disease models." | 4.02 | A serine protease inhibitor camostat mesilate prevents podocyte apoptosis and attenuates podocyte injury in metabolic syndrome model rats. ( Adachi, M; Deng, Q; Hayata, M; Iwata, Y; Izumi, Y; Kakizoe, Y; Kitamura, K; Kuwabara, T; Miyasato, Y; Miyoshi, T; Mizumoto, T; Morinaga, J; Mukoyama, M; Nakagawa, T; Sakai, Y; Tomita, K; Uchimura, K, 2021) |
| "Treatment with camostat mesilate or FOY-251 decreased equivalent current (Ieq) in M-1 cells in a dose-dependent manner and inhibited the protease activity of prostasin in vitro." | 1.35 | Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension. ( Adachi, M; Kakizoe, Y; Kitamura, K; Ko, T; Maekawa, A; Miyoshi, T; Shiraishi, N; Tomita, K; Wakida, N, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iwata, Y | 2 |
| Deng, Q | 2 |
| Kakizoe, Y | 3 |
| Nakagawa, T | 2 |
| Miyasato, Y | 2 |
| Nakagawa, M | 1 |
| Nishiguchi, K | 1 |
| Nagayoshi, Y | 1 |
| Narita, Y | 1 |
| Izumi, Y | 2 |
| Kuwabara, T | 2 |
| Adachi, M | 3 |
| Mukoyama, M | 2 |
| Mizumoto, T | 1 |
| Uchimura, K | 1 |
| Hayata, M | 1 |
| Morinaga, J | 1 |
| Miyoshi, T | 2 |
| Sakai, Y | 1 |
| Tomita, K | 3 |
| Kitamura, K | 3 |
| Maekawa, A | 1 |
| Wakida, N | 1 |
| Ko, T | 1 |
| Shiraishi, N | 1 |
1 review available for camostat and Blood Pressure, High
| Article | Year |
|---|---|
Proteolytic activation of the epithelial sodium channel and therapeutic application of a serine protease inhibitor for the treatment of salt-sensitive hypertension.
Topics: Animals; Epithelial Sodium Channels; Esters; Furin; Gabexate; Guanidines; Humans; Hypertension; Rats | 2012 |
3 other studies available for camostat and Blood Pressure, High
| Article | Year |
|---|---|
A Serine Protease Inhibitor, Camostat Mesilate, Suppresses Urinary Plasmin Activity and Alleviates Hypertension and Podocyte Injury in Dahl Salt-Sensitive Rats.
Topics: Animals; Blood Pressure; Fibrinolysin; Hypertension; Kidney; Podocytes; Proteinuria; Rats; Rats, Inb | 2023 |
A serine protease inhibitor camostat mesilate prevents podocyte apoptosis and attenuates podocyte injury in metabolic syndrome model rats.
Topics: Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Esters; Guanidines; Hypertension; Male; | 2021 |
Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Cells, Cultured; Esters; Gabexate; Gu | 2009 |