camostat has been researched along with Acute Edematous Pancreatitis in 30 studies
camostat : A benzoate ester resulting from the formal condensation of the carboxy group of 4-guanidinobenzoic acid with the hydroxy group of 2-(dimethylamino)-2-oxoethyl (4-hydroxyphenyl)acetate. It is a potent inhibitor of the human transmembrane protease serine 2 (TMPRSS2) and its mesylate salt is currently under investigation for its effectiveness in COVID-19 patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ciprofloxacin is considered to be a safe and effective treatment for acute infectious colitis." | 7.80 | Acute pancreatitis secondary to ciprofloxacin therapy in patients with infectious colitis. ( Cheung, DY; Cho, HJ; Cho, SH; Kim, JI; Kim, JK; Kim, SS; Lee, HJ; Sung, HY, 2014) |
| "Camostat mesilate (CM), an oral protease inhibitor, has been used clinically for the treatment of chronic pancreatitis in Japan." | 7.73 | Camostat mesilate attenuates pancreatic fibrosis via inhibition of monocytes and pancreatic stellate cells activity. ( Arita, Y; Fujimori, N; Gibo, J; Hisano, T; Inoue, M; Ito, T; Kawabe, K; Nawata, H; Oono, T, 2005) |
| "An oral protease inhibitor, camostat mesilate (CM) has been used clinically for chronic pancreatitis (CP) in Japan, but it lacks enough scientific evidence of its effectiveness." | 7.71 | Effect of camostat mesilate on the expression of pancreatitis-associated protein (PAP), p8, and cytokines in rat spontaneous chronic pancreatitis. ( Iovanna, JL; Motoo, Y; Sawabu, N; Su, SB; Xie, MJ, 2001) |
| "An experimental model of chronic pancreatitis was induced by a retrograde injection of a viscous solution consisting of zein-oleic acid-linoleic acid (0." | 7.70 | Pathophysiologic studies of experimental chronic pancreatitis in rats induced by injection of zein-oleic acid-linoleic acid solution into the pancreatic duct. ( Kashima, K; Kataoka, K; Sakagami, J; Sasaki, T; Yorizumi, H, 1998) |
| "The present study investigates the effect of oral pretreatment with the protease inhibitor camostate on the outcome of pancreatitis in three experimental models." | 7.68 | Effect of camostate administration for two weeks on experimental pancreatitis in mice and rats. ( Creutzfeldt, W; Leonhardt, U; Seidensticker, F; Stöckmann, F, 1993) |
| "The therapeutic effect and the mechanism of action of the synthetic trypsin inhibitor camostate were studied in a rat model of acute interstitial pancreatitis induced by four subcutaneous injections of 20 micrograms/kg body weight of cerulein at hourly intervals." | 7.68 | Beneficial effects of the synthetic trypsin inhibitor camostate in cerulein-induced acute pancreatitis in rats. ( Fuji, M; Fujisawa, T; Itoh, H; Nakamura, T; Okabayashi, Y; Otsuki, M; Tani, S, 1990) |
| "The effect of peritoneal lavage with the addition of camostate to the lavage fluid on the outcome of taurocholate pancreatitis in rats was studied." | 7.68 | Camostate (FOY-305) improves the therapeutic effect of peritoneal lavage on taurocholate induced pancreatitis. ( Creutzfeldt, W; Fussek, M; Leonhardt, U; Seidensticker, F; Stöckmann, F, 1990) |
| "Two models of severe acute pancreatitis were chosen and pancreatitis induced by sodium taurocholate and by a choline-deficient ethionine-supplemented diet, to evaluate the effectiveness of FOY-305 (camostate), a new synthetic trypsin inhibitor." | 7.67 | Effect of FOY-305 (camostate) on severe acute pancreatitis in two experimental animal models. ( Göke, B; Gröne, HJ; Lankisch, PG; Otto, J; Pohl, U; Rahlf, G; Wereszczynska-Siemiatkowska, U, 1989) |
| "Comparing the two groups of acute pancreatitis patients after 6 days of treatment with gabexate mesilate, we observed a statistically significantly lower alpha-amylase activity in the serum of treated patients compared with the placebo group." | 5.27 | Gabexate mesilate and camostate: new inhibitors of phospholipase A2 and their influence on the alpha-amylase activity in serum of patients with acute pancreatitis. ( Freise, J; Magerstedt, P; Schmid, K; Schmidt, FW, 1985) |
| "Ciprofloxacin is considered to be a safe and effective treatment for acute infectious colitis." | 3.80 | Acute pancreatitis secondary to ciprofloxacin therapy in patients with infectious colitis. ( Cheung, DY; Cho, HJ; Cho, SH; Kim, JI; Kim, JK; Kim, SS; Lee, HJ; Sung, HY, 2014) |
| "Camostat mesilate, an orally available proteinase inhibitor, is clinically used for treatment of pancreatitis." | 3.74 | The proteinase inhibitor camostat mesilate suppresses pancreatic pain in rodents. ( Ishiki, T; Ishikura, H; Kamanaka, Y; Kawabata, A; Matsunami, M; Nakatani, T; Naruse, M; Nishimura, S; Sekiguchi, F; Tsujiuchi, T, 2007) |
| "Camostat mesilate (CM), an oral protease inhibitor, has been used clinically for the treatment of chronic pancreatitis in Japan." | 3.73 | Camostat mesilate attenuates pancreatic fibrosis via inhibition of monocytes and pancreatic stellate cells activity. ( Arita, Y; Fujimori, N; Gibo, J; Hisano, T; Inoue, M; Ito, T; Kawabe, K; Nawata, H; Oono, T, 2005) |
| "An oral protease inhibitor, camostat mesilate (CM) has been used clinically for chronic pancreatitis (CP) in Japan, but it lacks enough scientific evidence of its effectiveness." | 3.71 | Effect of camostat mesilate on the expression of pancreatitis-associated protein (PAP), p8, and cytokines in rat spontaneous chronic pancreatitis. ( Iovanna, JL; Motoo, Y; Sawabu, N; Su, SB; Xie, MJ, 2001) |
| "An experimental model of chronic pancreatitis was induced by a retrograde injection of a viscous solution consisting of zein-oleic acid-linoleic acid (0." | 3.70 | Pathophysiologic studies of experimental chronic pancreatitis in rats induced by injection of zein-oleic acid-linoleic acid solution into the pancreatic duct. ( Kashima, K; Kataoka, K; Sakagami, J; Sasaki, T; Yorizumi, H, 1998) |
| "The effect of methylcarbonylmethyl 2(S)-14-(4-guanidino-benzoyloxy) phenyl] propionate methanesulfonate (TT-S24) on experimental pancreatitis in rats was examined in comparison with that of camostat." | 3.70 | Effect of methylcarbonylmethyl 2(S)-[4-(4-guanidino-benzoyloxy)phenyl] propionate methanesulfonate (TT-S24) on experimental pancreatitis in rats. ( Abe, S; Kamei, C; Tagami, H; Tanaka, I; Yoshida, Y, 1998) |
| "The effect of oral administration of protease inhibitor (camostat) on pancreatic morphology and exocrine function (conscious rat model) was investigated using WBN/Kob rats with spontaneous chronic pancreatitis." | 3.69 | Effect of oral administration of protease inhibitor on pancreatic exocrine function in WBN/Kob rats with chronic pancreatitis. ( Atomi, Y; Kobori, O; Kuroda, A; Muto, T; Sugiyama, M; Wada, N, 1996) |
| "We evaluated the protective effect of the CCK receptor antagonist L-364,718 (devazepide) and of the trypsin inhibitor camostat, on taurocholate-induced pancreatitis in rats." | 3.69 | The cholecystokinin receptor antagonist L-364,718 reduces taurocholate-induced pancreatitis in rats. ( Kim, DG; Kim, KH; Lee, MG, 1996) |
| "Effects of a new cholecystokinin (CCK)A-receptor antagonist, T-0632 [sodium (S)-1-(2-fluorophenyl)-2, 3-dihydro-3-[(3-isoquinolinylcarbonyl) amino]-6-methoxy-2-oxo-1H-indole-3-propanoate], on caerulein-induced and pancreatic duct ligation-induced pancreatitis models were studied and compared with the CCKA-receptor antagonist loxiglumide and the orally active protease inhibitor camostate, respectively." | 3.69 | Effect of T-0632, a cholecystokininA receptor antagonist, on experimental acute pancreatitis. ( Endo, T; Kume, E; Nagasaki, M; Shikano, T; Taniguchi, H; Yomota, E, 1997) |
| "The present study investigates the effect of oral pretreatment with the protease inhibitor camostate on the outcome of pancreatitis in three experimental models." | 3.68 | Effect of camostate administration for two weeks on experimental pancreatitis in mice and rats. ( Creutzfeldt, W; Leonhardt, U; Seidensticker, F; Stöckmann, F, 1993) |
| "The therapeutic effect and the mechanism of action of the synthetic trypsin inhibitor camostate were studied in a rat model of acute interstitial pancreatitis induced by four subcutaneous injections of 20 micrograms/kg body weight of cerulein at hourly intervals." | 3.68 | Beneficial effects of the synthetic trypsin inhibitor camostate in cerulein-induced acute pancreatitis in rats. ( Fuji, M; Fujisawa, T; Itoh, H; Nakamura, T; Okabayashi, Y; Otsuki, M; Tani, S, 1990) |
| " Caerulein-induced pancreatitis or treatment with the synthetic protease inhibitor camostate had no significant effects on permeability." | 3.68 | Pancreatic microvascular permeability in caerulein-induced acute pancreatitis. ( Mann, GE; Sweiry, JH, 1991) |
| "The effect of peritoneal lavage with the addition of camostate to the lavage fluid on the outcome of taurocholate pancreatitis in rats was studied." | 3.68 | Camostate (FOY-305) improves the therapeutic effect of peritoneal lavage on taurocholate induced pancreatitis. ( Creutzfeldt, W; Fussek, M; Leonhardt, U; Seidensticker, F; Stöckmann, F, 1990) |
| "Two models of severe acute pancreatitis were chosen and pancreatitis induced by sodium taurocholate and by a choline-deficient ethionine-supplemented diet, to evaluate the effectiveness of FOY-305 (camostate), a new synthetic trypsin inhibitor." | 3.67 | Effect of FOY-305 (camostate) on severe acute pancreatitis in two experimental animal models. ( Göke, B; Gröne, HJ; Lankisch, PG; Otto, J; Pohl, U; Rahlf, G; Wereszczynska-Siemiatkowska, U, 1989) |
| "Comparing the two groups of acute pancreatitis patients after 6 days of treatment with gabexate mesilate, we observed a statistically significantly lower alpha-amylase activity in the serum of treated patients compared with the placebo group." | 1.27 | Gabexate mesilate and camostate: new inhibitors of phospholipase A2 and their influence on the alpha-amylase activity in serum of patients with acute pancreatitis. ( Freise, J; Magerstedt, P; Schmid, K; Schmidt, FW, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (20.00) | 18.7374 |
| 1990's | 15 (50.00) | 18.2507 |
| 2000's | 7 (23.33) | 29.6817 |
| 2010's | 2 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sung, HY | 1 |
| Kim, JI | 1 |
| Lee, HJ | 1 |
| Cho, HJ | 1 |
| Cheung, DY | 1 |
| Kim, SS | 1 |
| Cho, SH | 1 |
| Kim, JK | 1 |
| Jia, D | 1 |
| Yamamoto, M | 1 |
| Otsuki, M | 2 |
| Suto, S | 1 |
| Okuaki, Y | 1 |
| Matsuoka, M | 1 |
| Enomoto, Y | 1 |
| Tsuruta, Y | 1 |
| Miyagawa, Y | 1 |
| Saito, A | 1 |
| Aizawa, Y | 1 |
| Toda, G | 1 |
| Kamisawa, T | 1 |
| Jiang, PH | 1 |
| Motoo, Y | 2 |
| Iovanna, JL | 2 |
| Pébusque, MJ | 1 |
| Xie, MJ | 2 |
| Okada, G | 1 |
| Sawabu, N | 2 |
| Inoue, N | 1 |
| Ito, T | 2 |
| Akashi, T | 1 |
| Kawabe, K | 2 |
| Oono, T | 2 |
| Gibo, J | 2 |
| Arita, Y | 2 |
| Nawata, H | 2 |
| Funakoshi, A | 1 |
| Hisano, T | 1 |
| Inoue, M | 1 |
| Fujimori, N | 1 |
| Ishikura, H | 1 |
| Nishimura, S | 1 |
| Matsunami, M | 1 |
| Tsujiuchi, T | 1 |
| Ishiki, T | 1 |
| Sekiguchi, F | 1 |
| Naruse, M | 1 |
| Nakatani, T | 1 |
| Kamanaka, Y | 1 |
| Kawabata, A | 1 |
| Leonhardt, U | 2 |
| Seidensticker, F | 2 |
| Stöckmann, F | 2 |
| Creutzfeldt, W | 2 |
| Kisfalvi, K | 1 |
| Papp, M | 1 |
| Friess, H | 1 |
| Büchler, M | 1 |
| Gorácz, UG | 1 |
| Yamamoto, Y | 1 |
| Sugiyama, M | 2 |
| Kobori, O | 1 |
| Atomi, Y | 2 |
| Wada, N | 2 |
| Kuroda, A | 2 |
| Muto, T | 2 |
| Kim, KH | 1 |
| Lee, MG | 1 |
| Kim, DG | 1 |
| Taniguchi, H | 1 |
| Yomota, E | 1 |
| Kume, E | 1 |
| Shikano, T | 1 |
| Endo, T | 1 |
| Nagasaki, M | 1 |
| Kataoka, K | 1 |
| Sasaki, T | 1 |
| Yorizumi, H | 1 |
| Sakagami, J | 1 |
| Kashima, K | 1 |
| Tagami, H | 1 |
| Abe, S | 1 |
| Yoshida, Y | 1 |
| Tanaka, I | 1 |
| Kamei, C | 1 |
| Yuasa, C | 1 |
| Irimura, K | 1 |
| Oda, M | 1 |
| Fukui, K | 1 |
| Oka, T | 1 |
| Su, SB | 1 |
| Tani, S | 1 |
| Okabayashi, Y | 1 |
| Fuji, M | 1 |
| Nakamura, T | 1 |
| Fujisawa, T | 1 |
| Itoh, H | 1 |
| Yoshida, K | 1 |
| Toki, F | 1 |
| Takeuchi, T | 1 |
| Takeda, K | 1 |
| Sweiry, JH | 1 |
| Mann, GE | 1 |
| Fussek, M | 1 |
| Freise, J | 1 |
| Schmidt, FW | 1 |
| Magerstedt, P | 1 |
| Schmid, K | 1 |
| Ohshio, G | 1 |
| Saluja, AK | 1 |
| Leli, U | 1 |
| Sengupta, A | 1 |
| Steer, ML | 1 |
| Redmond, HP | 1 |
| Leahy, AL | 1 |
| Keane, FB | 1 |
| Tanner, WA | 1 |
| Lankisch, PG | 2 |
| Pohl, U | 2 |
| Göke, B | 1 |
| Otto, J | 2 |
| Wereszczynska-Siemiatkowska, U | 1 |
| Gröne, HJ | 1 |
| Rahlf, G | 1 |
| Yamasaki, Y | 1 |
| Kuroshima, T | 1 |
| Tsuji, K | 1 |
| Kawamoto, H | 1 |
| Higashimoto, Y | 1 |
3 reviews available for camostat and Acute Edematous Pancreatitis
| Article | Year |
|---|---|
[A case of groove pancreatitis pure type treated with conservative therapy].
Topics: Chronic Disease; Drug Therapy, Combination; Esters; Gabexate; Guanidines; Humans; Magnetic Resonance | 2003 |
[Autoimmune pancreatitis].
Topics: Autoimmune Diseases; Diagnostic Imaging; Diet, Fat-Restricted; Drainage; Esters; Fasting; Gabexate; | 2004 |
[Clinical study of chronic pancreatitis].
Topics: Alcohol Drinking; Cholangiopancreatography, Endoscopic Retrograde; Chronic Disease; Esters; Fasting; | 1993 |
27 other studies available for camostat and Acute Edematous Pancreatitis
| Article | Year |
|---|---|
Acute pancreatitis secondary to ciprofloxacin therapy in patients with infectious colitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infectio | 2014 |
Effect of endogenous cholecystokinin on the course of acute pancreatitis in rats.
Topics: Administration, Oral; Animals; Biomarkers; Bombesin; Cell Proliferation; Cholecystokinin; Disease Mo | 2015 |
Tumor protein p53-induced nuclear protein 1 (TP53INP1) in spontaneous chronic pancreatitis in the WBN/Kob rat: drug effects on its expression in the pancreas.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Arginine; Carrier Proteins; Cell Line; Chronic Di | 2004 |
Acute pancreatitis in the early stages of pregnancy associated with a PSTI gene mutation.
Topics: Abdominal Pain; Acute Disease; Adult; Amino Acid Substitution; Amylases; Carrier Proteins; Diet, Fat | 2004 |
Camostat mesilate attenuates pancreatic fibrosis via inhibition of monocytes and pancreatic stellate cells activity.
Topics: Animals; Cell Proliferation; Chemokine CCL2; Disease Models, Animal; Dose-Response Relationship, Dru | 2005 |
The proteinase inhibitor camostat mesilate suppresses pancreatic pain in rodents.
Topics: Abdominal Pain; Animals; Ceruletide; Dose-Response Relationship, Drug; Esters; Gabexate; Guanidines; | 2007 |
Effect of camostate administration for two weeks on experimental pancreatitis in mice and rats.
Topics: Administration, Oral; Amylases; Animals; Cholecystokinin; Esters; Female; Gabexate; Guanidines; Male | 1993 |
Beneficial effects of preventive oral administration of camostate on cerulein-induced pancreatitis in rats.
Topics: Administration, Oral; Animals; Ceruletide; Esters; Gabexate; Guanidines; Pancreatitis; Rats; Rats, W | 1995 |
Effect of oral administration of protease inhibitor on pancreatic exocrine function in WBN/Kob rats with chronic pancreatitis.
Topics: Administration, Oral; Animals; Cholecystokinin; Chronic Disease; Disease Models, Animal; Esters; Gab | 1996 |
The cholecystokinin receptor antagonist L-364,718 reduces taurocholate-induced pancreatitis in rats.
Topics: Amylases; Animals; Benzodiazepinones; Cholagogues and Choleretics; Devazepide; Esters; Gabexate; Gua | 1996 |
Effect of T-0632, a cholecystokininA receptor antagonist, on experimental acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Ceruletide; Disease Models, Animal; Dogs; Esters; Female; Gabexate | 1997 |
Effect of oral protease inhibitor administration on gallbladder motility in patients with mild chronic pancreatitis.
Topics: Administration, Oral; Adult; Aged; Cholecystokinin; Chronic Disease; Esters; Female; Gabexate; Gallb | 1997 |
Pathophysiologic studies of experimental chronic pancreatitis in rats induced by injection of zein-oleic acid-linoleic acid solution into the pancreatic duct.
Topics: Amylases; Animals; Blood Glucose; Body Weight; Chronic Disease; Disease Models, Animal; Esters; Gabe | 1998 |
Effect of methylcarbonylmethyl 2(S)-[4-(4-guanidino-benzoyloxy)phenyl] propionate methanesulfonate (TT-S24) on experimental pancreatitis in rats.
Topics: Amylases; Animals; Ceruletide; Disease Models, Animal; Esters; Gabexate; Guanidines; Male; Pancreati | 1998 |
Oral administration of sepimostat mesilate prevents acute alcohol pancreatic injury in rats.
Topics: Acute Disease; Administration, Oral; Amylases; Animals; Ceruletide; Esters; Ethanol; Gabexate; Guani | 1999 |
Effect of camostat mesilate on the expression of pancreatitis-associated protein (PAP), p8, and cytokines in rat spontaneous chronic pancreatitis.
Topics: Acute-Phase Proteins; Animals; Antigens, Neoplasm; Basic Helix-Loop-Helix Transcription Factors; Bio | 2001 |
Beneficial effects of the synthetic trypsin inhibitor camostate in cerulein-induced acute pancreatitis in rats.
Topics: Acute Disease; Amylases; Animals; Ceruletide; Esters; Gabexate; Guanidines; Male; Organ Size; Pancre | 1990 |
[Antienzyme preparations in the treatment of acute pancreatitis].
Topics: Acute Disease; Adult; Aprotinin; Benzamidines; Cytidine Diphosphate Choline; Disseminated Intravascu | 1990 |
[Protease inhibitors in the treatment of pancreatitis].
Topics: Acute Disease; Animals; Aprotinin; Chronic Disease; Esters; Gabexate; Glycoproteins; Guanidines; Hum | 1991 |
Pancreatic microvascular permeability in caerulein-induced acute pancreatitis.
Topics: Acute Disease; Animals; Capillary Permeability; Ceruletide; Edetic Acid; Endothelium, Vascular; Este | 1991 |
Camostate (FOY-305) improves the therapeutic effect of peritoneal lavage on taurocholate induced pancreatitis.
Topics: Acute Disease; Animals; Esters; Gabexate; Guanidines; Male; Pancreatitis; Peritoneal Lavage; Proteas | 1990 |
Gabexate mesilate and camostate: new inhibitors of phospholipase A2 and their influence on the alpha-amylase activity in serum of patients with acute pancreatitis.
Topics: Acute Disease; alpha-Amylases; Aprotinin; Esters; Gabexate; Guanidines; Humans; Infusions, Parentera | 1985 |
Esterase inhibitors prevent lysosomal enzyme redistribution in two noninvasive models of experimental pancreatitis.
Topics: Amylases; Animals; Cathepsin B; Esters; Gabexate; Guanidines; Male; Pancreas; Pancreatitis; Protease | 1989 |
Effect of FOY-305 (Camostate) on severe acute pancreatitis in two experimental animal models.
Topics: Acute Disease; Animals; Disease Models, Animal; Esters; Gabexate; Guanidines; Pancreatitis; Rats; Ra | 1989 |
Effect of FOY-305 (camostate) on severe acute pancreatitis in two experimental animal models.
Topics: Acute Disease; Animals; Choline Deficiency; Esters; Female; Gabexate; Guanidines; Male; Mice; Pancre | 1989 |
Synthetic versus natural protease inhibitors in acute experimental pancreatitis.
Topics: Animals; Esters; Gabexate; Guanidines; Male; Pancreatitis; Plasma; Protease Inhibitors; Rats | 1988 |
[Protective effect of camostat mesilate and allopurinol in acute edematous pancreatitis in the rat induced by excessive doses of caerulein].
Topics: Acute Disease; Allopurinol; Animals; Ceruletide; Edema; Esters; Gabexate; Guanidines; Male; Pancreat | 1987 |