cambinol and Body-Weight

cambinol has been researched along with Body-Weight* in 1 studies

Other Studies

1 other study(ies) available for cambinol and Body-Weight

ArticleYear
Novel Human Neutral Sphingomyelinase 2 Inhibitors as Potential Therapeutics for Alzheimer's Disease.
    Journal of medicinal chemistry, 2020, 06-11, Volume: 63, Issue:11

    Neutral sphingomyelinase 2 (nSMase2) catalyzes the cleavage of sphingomyelin to phosphorylcholine and ceramide, an essential step in the formation and release of exosomes from cells that is critical for intracellular communication. Chronic increase of brain nSMase2 activity and related exosome release have been implicated in various pathological processes, including the progression of Alzheimer's disease (AD), making nSMase2 a viable therapeutic target. Recently, we identified phenyl (

    Topics: Alzheimer Disease; Animals; Body Weight; Brain; Disease Models, Animal; Enzyme Inhibitors; Exosomes; Female; Humans; Male; Mice; Mice, Transgenic; Pyridazines; Sphingomyelin Phosphodiesterase; Structure-Activity Relationship

2020