calpastatin and Cardiovascular-Diseases

calpastatin has been researched along with Cardiovascular-Diseases* in 1 studies

Reviews

1 review(s) available for calpastatin and Cardiovascular-Diseases

Article	Year
[The physiological and pathological function of Ca(2 +) -dependent cysteine protease (Calpain) ]. Clinical calcium, 2013, Volume: 23, Issue:4 Calpains are Ca(2 +) -dependent cysteine proteases. Fifteen gene products of calpains are expressed in mammals. Among them, Calpain 1 and Calpain 2 are ubiquitously expressed and have been investigated extensively. Under the physiological conditions, calpain activity is strictly regulated by endogenous inhibitory protein, Calpastatin. Calpains are activated in the various cardiovascular diseases and implicated in their pathogenesis by degrading numerous target proteins. Here we briefly summarize the physiological and pathological role of calpains in the cardiovascular diseases. Topics: Animals; Calcium; Calcium-Binding Proteins; Calpain; Cardiovascular Diseases; Genetic Predisposition to Disease; Humans	2013

Article

Year

[The physiological and pathological function of Ca(2 +) -dependent cysteine protease (Calpain) ].

Clinical calcium, 2013, Volume: 23, Issue:4

Calpains are Ca(2 +) -dependent cysteine proteases. Fifteen gene products of calpains are expressed in mammals. Among them, Calpain 1 and Calpain 2 are ubiquitously expressed and have been investigated extensively. Under the physiological conditions, calpain activity is strictly regulated by endogenous inhibitory protein, Calpastatin. Calpains are activated in the various cardiovascular diseases and implicated in their pathogenesis by degrading numerous target proteins. Here we briefly summarize the physiological and pathological role of calpains in the cardiovascular diseases.

Topics: Animals; Calcium; Calcium-Binding Proteins; Calpain; Cardiovascular Diseases; Genetic Predisposition to Disease; Humans

2013