calpain and Rotator-Cuff-Injuries

calpain has been researched along with Rotator-Cuff-Injuries* in 1 studies

Other Studies

1 other study(ies) available for calpain and Rotator-Cuff-Injuries

Article	Year
Inhibition of calpain delays early muscle atrophy after rotator cuff tendon release in sheep. Physiological reports, 2018, Volume: 6, Issue:21 Chronic rotator cuff (RC) tears are characterized by retraction, fat accumulation, and atrophy of the affected muscle. These features pose an intractable problem for surgical repair and subsequent recovery, and their prevention may be easier than reversal. Using an established ovine model, we tested the hypothesis that inhibition of the protease calpain mitigates m. infraspinatus atrophy by preservation of the myofibers' structural anchors in the sarcolemma (the costameres). Already 2 weeks of distal tendon release led to a reduction in muscle volume (-11.6 ± 9.1 cm Topics: Animals; Calpain; Cysteine Proteinase Inhibitors; Dipeptides; Female; Muscular Atrophy; Rotator Cuff Injuries; Sarcolemma; Sheep	2018

Article

Year

Inhibition of calpain delays early muscle atrophy after rotator cuff tendon release in sheep.

Physiological reports, 2018, Volume: 6, Issue:21

Chronic rotator cuff (RC) tears are characterized by retraction, fat accumulation, and atrophy of the affected muscle. These features pose an intractable problem for surgical repair and subsequent recovery, and their prevention may be easier than reversal. Using an established ovine model, we tested the hypothesis that inhibition of the protease calpain mitigates m. infraspinatus atrophy by preservation of the myofibers' structural anchors in the sarcolemma (the costameres). Already 2 weeks of distal tendon release led to a reduction in muscle volume (-11.6 ± 9.1 cm

Topics: Animals; Calpain; Cysteine Proteinase Inhibitors; Dipeptides; Female; Muscular Atrophy; Rotator Cuff Injuries; Sarcolemma; Sheep

2018