calmidazolium has been researched along with Disorders of Sex Development in 3 studies
calmidazolium: powerful inhibitor of or red blood cell Ca++-ATPase & Ca++ transport into inside-out red blood cell vesicles; RN refers to chloride; structure in first source; an antagonist of calmodulin
calmidazolium : An imidazolium ion that is imidazolium cation substituted by a bis(4-chlorophenyl)methyl group at position 1 and a 2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl group at position 3. It acts as an antagonist of calmodulin, a calcium binding messenger protein.
Disorders of Sex Development: In gonochoristic organisms, congenital conditions in which development of chromosomal, gonadal, or anatomical sex is atypical. Effects from exposure to abnormal levels of GONADAL HORMONES in the maternal environment, or disruption of the function of those hormones by ENDOCRINE DISRUPTORS are included.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In calmidazolium-treated cells, the dramatic reduction in nuclear entry of SRY and an SRY-c-NLS mutant was not observed for two SRY-n-NLS mutants." | 1.33 | Defective calmodulin-mediated nuclear transport of the sex-determining region of the Y chromosome (SRY) in XY sex reversal. ( Clayton, AH; Harley, VR; Kelly, S; Ludbrook, LM; Rimmer, K; Sim, H, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaur, G | 1 |
| Delluc-Clavieres, A | 1 |
| Poon, IK | 1 |
| Forwood, JK | 1 |
| Glover, DJ | 1 |
| Jans, DA | 2 |
| Argentaro, A | 1 |
| Sim, H | 2 |
| Kelly, S | 2 |
| Preiss, S | 1 |
| Clayton, A | 1 |
| Harley, VR | 2 |
| Rimmer, K | 1 |
| Ludbrook, LM | 1 |
| Clayton, AH | 1 |
3 other studies available for calmidazolium and Disorders of Sex Development
| Article | Year |
|---|---|
Calmodulin-dependent nuclear import of HMG-box family nuclear factors: importance of the role of SRY in sex reversal.
Topics: Active Transport, Cell Nucleus; Animals; beta Karyopherins; Calmodulin; Cell Line; Cell Nucleus; Chl | 2010 |
A SOX9 defect of calmodulin-dependent nuclear import in campomelic dysplasia/autosomal sex reversal.
Topics: Acrylamide; Active Transport, Cell Nucleus; Amino Acid Sequence; Animals; beta Karyopherins; Calmodu | 2003 |
Defective calmodulin-mediated nuclear transport of the sex-determining region of the Y chromosome (SRY) in XY sex reversal.
Topics: Active Transport, Cell Nucleus; Amino Acid Sequence; Animals; Calmodulin; Cell Nucleus; Chlorocebus | 2005 |