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calmidazolium and Chemical and Drug Induced Liver Injury

calmidazolium has been researched along with Chemical and Drug Induced Liver Injury in 1 studies

calmidazolium: powerful inhibitor of or red blood cell Ca++-ATPase & Ca++ transport into inside-out red blood cell vesicles; RN refers to chloride; structure in first source; an antagonist of calmodulin
calmidazolium : An imidazolium ion that is imidazolium cation substituted by a bis(4-chlorophenyl)methyl group at position 1 and a 2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl group at position 3. It acts as an antagonist of calmodulin, a calcium binding messenger protein.

Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment of galactosamine/TNF-alpha-injured mice with 800 mg/kg uridine or with 6 mg/kg calmidazolium fully protected the animals, while administration of either verapamil or nifedipine (100 mg/kg, respectively) had no significant effect."1.28Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice. ( Tiegs, G; Wendel, A; Wolter, M, 1989)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tiegs, G1
Wolter, M1
Wendel, A1

Other Studies

1 other study available for calmidazolium and Chemical and Drug Induced Liver Injury

ArticleYear
Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice.
    Biochemical pharmacology, 1989, Feb-15, Volume: 38, Issue:4

    Topics: Allopurinol; Animals; Chemical and Drug Induced Liver Injury; Eicosanoic Acids; Endotoxins; Epoprost

1989