calmidazolium has been researched along with Chemical and Drug Induced Liver Injury in 1 studies
calmidazolium: powerful inhibitor of or red blood cell Ca++-ATPase & Ca++ transport into inside-out red blood cell vesicles; RN refers to chloride; structure in first source; an antagonist of calmodulin
calmidazolium : An imidazolium ion that is imidazolium cation substituted by a bis(4-chlorophenyl)methyl group at position 1 and a 2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl group at position 3. It acts as an antagonist of calmodulin, a calcium binding messenger protein.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
Excerpt | Relevance | Reference |
---|---|---|
"Pretreatment of galactosamine/TNF-alpha-injured mice with 800 mg/kg uridine or with 6 mg/kg calmidazolium fully protected the animals, while administration of either verapamil or nifedipine (100 mg/kg, respectively) had no significant effect." | 1.28 | Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice. ( Tiegs, G; Wendel, A; Wolter, M, 1989) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Tiegs, G | 1 |
Wolter, M | 1 |
Wendel, A | 1 |
1 other study available for calmidazolium and Chemical and Drug Induced Liver Injury
Article | Year |
---|---|
Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice.
Topics: Allopurinol; Animals; Chemical and Drug Induced Liver Injury; Eicosanoic Acids; Endotoxins; Epoprost | 1989 |