calmidazolium has been researched along with Brain Ischemia in 2 studies
calmidazolium: powerful inhibitor of or red blood cell Ca++-ATPase & Ca++ transport into inside-out red blood cell vesicles; RN refers to chloride; structure in first source; an antagonist of calmodulin
calmidazolium : An imidazolium ion that is imidazolium cation substituted by a bis(4-chlorophenyl)methyl group at position 1 and a 2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl group at position 3. It acts as an antagonist of calmodulin, a calcium binding messenger protein.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Using an in vitro model of transient brain ischemia, we investigated possible protective effects of NMDA receptor antagonists ketamine or MK-801 and of calmidazolium, an inhibitor of intracellular Ca2(+)-activated proteins." | 3.68 | Ischemic brain injury in vitro: protective effects of NMDA receptor antagonists and calmidazolium. ( Becker, GL; Landers, DF; Pohorecki, R; Reilly, PJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, X | 1 |
| Shin, C | 1 |
| Windebank, AJ | 1 |
| Pohorecki, R | 1 |
| Becker, GL | 1 |
| Reilly, PJ | 1 |
| Landers, DF | 1 |
2 other studies available for calmidazolium and Brain Ischemia
| Article | Year |
|---|---|
Calmodulin in ischemic neurotoxicity of rat hippocampus in vitro.
Topics: Animals; Brain Ischemia; Calmodulin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hippocampu | 1997 |
Ischemic brain injury in vitro: protective effects of NMDA receptor antagonists and calmidazolium.
Topics: Adenosine Triphosphate; Animals; Brain Ischemia; Dizocilpine Maleate; Hippocampus; Imidazoles; In Vi | 1990 |