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calmidazolium and Acute Liver Injury, Drug-Induced

calmidazolium has been researched along with Acute Liver Injury, Drug-Induced in 1 studies

calmidazolium: powerful inhibitor of or red blood cell Ca++-ATPase & Ca++ transport into inside-out red blood cell vesicles; RN refers to chloride; structure in first source; an antagonist of calmodulin
calmidazolium : An imidazolium ion that is imidazolium cation substituted by a bis(4-chlorophenyl)methyl group at position 1 and a 2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl group at position 3. It acts as an antagonist of calmodulin, a calcium binding messenger protein.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment of galactosamine/TNF-alpha-injured mice with 800 mg/kg uridine or with 6 mg/kg calmidazolium fully protected the animals, while administration of either verapamil or nifedipine (100 mg/kg, respectively) had no significant effect."1.28Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice. ( Tiegs, G; Wendel, A; Wolter, M, 1989)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tiegs, G1
Wolter, M1
Wendel, A1

Other Studies

1 other study available for calmidazolium and Acute Liver Injury, Drug-Induced

ArticleYear
Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice.
    Biochemical pharmacology, 1989, Feb-15, Volume: 38, Issue:4

    Topics: Allopurinol; Animals; Chemical and Drug Induced Liver Injury; Eicosanoic Acids; Endotoxins; Epoprost

1989