calixarenes and Hepatitis-C

calixarenes has been researched along with Hepatitis-C* in 1 studies

Other Studies

1 other study(ies) available for calixarenes and Hepatitis-C

Article	Year
Discovery of a synthetic dual inhibitor of HIV and HCV infection based on a tetrabutoxy-calix[4]arene scaffold. Bioorganic & medicinal chemistry letters, 2010, Apr-01, Volume: 20, Issue:7 A potential anti-HIV and HCV drug candidate is highly desirable as coinfection has become a worldwide public health challenge. A potent compound based on a tetrabutoxy-calix[4]arene scaffold that possesses dual inhibition for both HIV and HCV is described. Structural activity relationship studies demonstrate the effects of lower-rim alkylation in maintaining cone conformation and upper-rim interacting head groups on the calix[4]arene play key roles for its potent dual antiviral activities. Topics: Antiviral Agents; Calixarenes; Cell Line; Cell Survival; Hepacivirus; Hepatitis C; HIV; HIV Infections; Inhibitory Concentration 50; Models, Molecular; Molecular Structure	2010

Article

Year

Discovery of a synthetic dual inhibitor of HIV and HCV infection based on a tetrabutoxy-calix[4]arene scaffold.

Bioorganic & medicinal chemistry letters, 2010, Apr-01, Volume: 20, Issue:7

A potential anti-HIV and HCV drug candidate is highly desirable as coinfection has become a worldwide public health challenge. A potent compound based on a tetrabutoxy-calix[4]arene scaffold that possesses dual inhibition for both HIV and HCV is described. Structural activity relationship studies demonstrate the effects of lower-rim alkylation in maintaining cone conformation and upper-rim interacting head groups on the calix[4]arene play key roles for its potent dual antiviral activities.

Topics: Antiviral Agents; Calixarenes; Cell Line; Cell Survival; Hepacivirus; Hepatitis C; HIV; HIV Infections; Inhibitory Concentration 50; Models, Molecular; Molecular Structure

2010