calix(4)arene and Alzheimer-Disease

calix(4)arene has been researched along with Alzheimer-Disease* in 1 studies

Other Studies

1 other study(ies) available for calix(4)arene and Alzheimer-Disease

Article	Year
Novel Peptide-Calix[4]arene Conjugate Inhibits Aβ Aggregation and Rescues Neurons from Aβ's Oligomers Cytotoxicity ACS chemical neuroscience, 2021, 04-21, Volume: 12, Issue:8 Alzheimer's disease (AD) is a progressive neurodegenerative condition affecting people in the elderly. Targeting aggregation of β-amyloid peptides (Aβ) is considered a promising approach for the therapeutic treatment of the disease. Peptide based inhibitors of β-amyloid fibrillation are emerging as safe drug candidates as well as interesting compounds for early diagnosis of AD. Peptide conjugation via covalent bond with functional moieties enables the resultant hybrid system to acquire desired functions. Here we report the synthesis, the structural characterization, and the Aβ Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Calixarenes; Humans; Neurons; Peptide Fragments; Phenols	2021

Article

Year

Novel Peptide-Calix[4]arene Conjugate Inhibits Aβ Aggregation and Rescues Neurons from Aβ's Oligomers Cytotoxicity

ACS chemical neuroscience, 2021, 04-21, Volume: 12, Issue:8

Alzheimer's disease (AD) is a progressive neurodegenerative condition affecting people in the elderly. Targeting aggregation of β-amyloid peptides (Aβ) is considered a promising approach for the therapeutic treatment of the disease. Peptide based inhibitors of β-amyloid fibrillation are emerging as safe drug candidates as well as interesting compounds for early diagnosis of AD. Peptide conjugation via covalent bond with functional moieties enables the resultant hybrid system to acquire desired functions. Here we report the synthesis, the structural characterization, and the Aβ

Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Calixarenes; Humans; Neurons; Peptide Fragments; Phenols

2021