calcium-sulfide and Acquired-Hyperostosis-Syndrome

We report on a young woman suffering from SAPHO syndrome with back pain and arthritis of the sternoclavicular joints. This inflammatory disorder of the osteoarticular system (synovitis, osteitis, and hyperostosis) is associated with severe acne or palmoplantar pustulosis. The patient was treated with pamidronate, NSAID and physiotherapy which improved the musculoskeletal symptoms completely. The acne was treated with isotretinoin.

Topics: Acne Vulgaris; Acquired Hyperostosis Syndrome; Administration, Oral; Administration, Topical; Adult; Anti-Inflammatory Agents; Back Pain; Calcium Compounds; Combined Modality Therapy; Diagnosis, Differential; Diphosphonates; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Isotretinoin; Naproxen; Pamidronate; Physical Therapy Modalities; Sulfides; Thiosulfates