calcitriol and Drug-Overdose

Vitamin D toxicity is associated with accidental overdoses due to manufacturing or intake errors and its secondary hypercalcemia can result in severe morbidity. Although patients with cystic fibrosis are potentially at increased risk for this intoxication as prescription of vitamin D preparations is a common practice in this population, the frequency of such events is currently unknown. We performed a retrospective analysis of all the files of cystic fibrosis patients followed at the Cliniques universitaires Saint-Luc over a 10-year period, recording 25(OH)- and 1,25(OH)

Topics: Adolescent; Adult; Cohort Studies; Cystic Fibrosis; Drug Overdose; Female; Humans; Male; Medication Errors; Retrospective Studies; Vitamin D; Young Adult