calcitonin has been researched along with Calcinosis* in 2 studies
2 other study(ies) available for calcitonin and Calcinosis
Article | Year |
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Prevention of experimental calcinosis by salmon calcitonin in rats.
The effects of salmon calcitonin on calcium overload and its deposition in the rat aorta was studied. Calcitonin administered 4 days to rats i.p. in doses of 10 IU/kg body weight blocked the development of calcinosis induced by a single dose of vitamin D3 (300,000 IU/kg body weight, orally). This was demonstrated biochemically, histochemically and by electron microscopic methods. Topics: Animals; Aorta; Aortic Diseases; Calcinosis; Calcitonin; Calcium; Cholecalciferol; Male; Rats; Rats, Inbred Strains | 1989 |
Effects of the acute subcutaneous administration of synthetic salmon calcitonin in tumoral calcinosis.
We examined the effects of the acute administration of salmon calcitonin on phosphate metabolism in tumoral calcinosis. On two different days, 200 MRC U of the synthetic hormone were administered sc to a 38-year-old patient, either as twice daily 100 MRC U injections, or as a continuous sc infusion via a portable pump. Both ways of calcitonin administration elicited a phosphaturic effect and a lowering of serum phosphate level comparable with that observed after an iv infusion of calcitonin. 1,25 dihydroxyvitamin D level, which was in the normal range during a control study, increased after calcitonin administration. In our patient, long term therapy with diet, a phosphate-binding agent and calcitonin prevented the occurrence of new ectopic calcifications. Owing to its phosphaturic activity, synthetic salmon calcitonin may be a useful adjunct to diet and aluminium-containing antacids in long-term management of tumoral calcinosis. Topics: Adult; Calcinosis; Calcitonin; Female; Hormones; Humans; Injections, Subcutaneous; Phosphates | 1989 |