calcipotriene and Neoplasms

Acanthosis nigricans is a dermatosis characterized by thickened, hyperpigmented plaques, typically of the intertriginous surfaces and neck. Common in some populations, its prevalence depends on race. Clinicians should recognize acanthosis nigricans; it heralds disorders ranging from endocrinologic disturbances to malignancy. In this review, we discuss the pathogenesis of acanthosis nigricans and its clinical implications and management.

Topics: Acanthosis Nigricans; Adolescent; Calcitriol; Child; Disease Susceptibility; Ethnicity; Female; Fish Oils; Humans; Hypoglycemic Agents; Insulin Resistance; Insulin-Like Growth Factor I; Low-Level Light Therapy; Male; Neoplasms; Prevalence; Receptor Protein-Tyrosine Kinases; Retinoids