calcipotriene and Acrodermatitis

Topics: Acrodermatitis; Administration, Cutaneous; Aged; Anti-Inflammatory Agents; Calcitriol; Clobetasol; Diagnosis, Differential; Fingers; Hand Dermatoses; Humans; Male; Nails, Malformed

Low level laser or light treatment on the various clinical condition is getting considerable attention now. However, there has been no report about the clinical effect of low level polarized polychromatic noncoherent light (LPPL) on the inflammatory skin disease. We experienced a case of acrodermatitis continua in a pregnant woman refractory to any conventional treatment including the most potent topical steroid. She was successfully treated with LPPL. LPPL could be a possible treatment modality producing substantial clinical result in inflammatory skin condition without any side-effect.

Topics: Acrodermatitis; Adult; Calcitriol; Female; Humans; Inflammation; Light; Phototherapy; Pregnancy; Pregnancy Complications; Psoriasis; Skin Diseases

To investigate the efficacy of treating acrodermatitis continua of Hallopeau (ACH) with a new two-compound ointment.. ACH is a rare pustular eruption on the distal portions of the fingers and less often, on the toes. It is nowadays classified as a form of acropustular psoriasis that tends to be resistant to treatment.. A 75-year old woman presented with pustules and hyperkeratotic erythematous papules, coalescing in plaques on the dorsal aspect of both great toes and on the perionychium of their nails. Diagnosis of ACH was based on clinical and histologic findings. We treated the patient with application of an ointment containing calcipotriol and betamethasone dipropionate twice daily for a month.. Therapeutic effect of the applied agent was impressively rapid with complete recovery of the lesions. In our patient, calcipotriol/ betamethasone dipropionate ointment was an efficacious regimen in the treatment of ACH. In the era of biologics, old topical agents in combined forms remain valuable. Although calcipotriol alone or its combination with betamethasone have been reported to aggravate the disease in some cases, their beneficial role is important and they are worth considering as first line therapeutic agents in the management of various forms of pustular psoriasis.

Topics: Acrodermatitis; Administration, Topical; Aged; Betamethasone; Calcitriol; Dermatologic Agents; Drug Combinations; Female; Humans; Psoriasis; Skin

Acrodermatitis continua of Hallopeau (ACH) is a rare chronic pustular eruption that predominantly involves the fingertips. The characterization of this disease has been confused. Some have considered it as a separate entity while others as a variant of pustular psoriasis. The presented patient simultaneously had ACH and joint lesions which were diagnosed as psoriatic arthritis. We believe that because ACH may be accompanied by psoriatic arthritis, as in this case, it could be evidence that it is a variant of psoriasis.

Topics: Acrodermatitis; Administration, Cutaneous; Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Psoriatic; Calcitriol; Celecoxib; Dermatologic Agents; Diagnosis, Differential; Humans; Male; Pyrazoles; Radiography; Sulfasalazine; Sulfonamides

Acrodermatitis continua of Hallopeau (ACH) is a rare type of pustular psoriasis affecting the digits. We report on a 43-year-old female patient who had been suffering from ACH for more than 20 years. Despite the fact that the disease was localized on one finger during the whole period, several topical and systemic treatments resulted in only temporary or partial improvement of the lesion. Although the monotherapies with calcipotriol and tacrolimus ointments gave no satisfying results in the long-term management of the disease, the combination of both agents led to a continuous improvement of the patient's skin condition.

Topics: Acrodermatitis; Administration, Cutaneous; Adult; Calcitriol; Dermatologic Agents; Drug Combinations; Female; Hand Dermatoses; Humans; Immunosuppressive Agents; Ointments; Psoriasis; Tacrolimus

Topics: Acrodermatitis; Administration, Topical; Aged; Calcitriol; Dermatologic Agents; Humans; Male; Middle Aged

Topics: Acrodermatitis; Adult; Calcitriol; Dermatologic Agents; Humans; Male; Ointments

Treatment of acrodermatitis continua of Hallopeau (ACH) is difficult and often disappointing. We describe a patient with an extensive ACH of all finger- and toetips, who was treated with acitretin combined with calcipotriol. A within-subject left/right comparison was carried out between calcipotriol ointment (50 micrograms/g) and the ointment base to investigate the additional value of calcipotriol above the ointment base. The side treated with calcipotriol as adjunct therapy showed an impressive improvement, well beyond the degree of improvement at the side treated with the ointment base only.

Topics: Acitretin; Acrodermatitis; Aged; Calcitriol; Dermatologic Agents; Drug Synergism; Drug Therapy, Combination; Female; Humans; Neutrophils; Ointments

We report a 71-year-old woman who had severe inflammatory acrodermatitis continua of Hallopeau. The administration of local remedies, soft X-rays and a number of systemic treatments resulted only in transient and incomplete resolution of the lesions. The pustules, increased skin fragility, tender oedema and erythema were successfully controlled by the local administration of calcipotriol.

Topics: Acrodermatitis; Aged; Calcitriol; Dermatologic Agents; Female; Hallux; Humans