calcimycin has been researched along with Precancerous-Conditions* in 1 studies
1 other study(ies) available for calcimycin and Precancerous-Conditions
| Article | Year |
|---|---|
[The activation of the early chemiluminescent response of human neutrophils by joint treatment with tumor necrosis factor (TNF-alpha) and the calcium ionophore A-23187].
The influence of recombinant human tumor necrosis factor-alpha (TNF-alpha) and calcium ionophore A23187 on luminol- and lucigenin-dependent chemiluminescence capacity (CL) of human polymorphonuclear leukocytes (PMN) has been studied. The CL response of TNF-alpha treated PMN is amplified by lucigenin, but not luminol. TNF-alpha and A23287 synergistically induced both the luminol- and lucigenin-dependent early CL response. The combination of A23187 and activator of protein kinase C--phorbol (myristoyl-13-acetyl)--also provoked early CL response. While the combination of TNF-alpha and A23187 decreased late CL response compared to A23187 alone. The obtained results suggests that synergistic CL response of PMN induced by TNF-alpha and A23187 is connected with activation of protein kinase by TNF-alpha. Topics: Acridines; Calcimycin; Cells, Cultured; Humans; Luminescent Measurements; Luminol; Neutrophils; Oxygen; Precancerous Conditions; Recombinant Proteins; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 1991 |