calcimycin has been researched along with Churg-Strauss-Syndrome* in 1 studies
1 other study(ies) available for calcimycin and Churg-Strauss-Syndrome
Article | Year |
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Cellular communication in leukotriene C4 production between eosinophils and neutrophils.
Eosinophilic granulocytes as well as neutrophilic granulocytes produced leukotriene C4 (LTC4) on stimulation with 1 microM A23187 (Ca2+ ionophore). In healthy volunteers, the LTC4 production in eosinophils was about 3 times the production in neutrophils. Within 15 min greater than 90% of the LTC4 was released into the supernatant. Stimulation of eosinophils and neutrophils together resulted in a synergistic increase in LTC4 production of 306 +/- 40%. LTC4 synthesis by hypodense eosinophils was also enhanced if stimulated in the presence of neutrophils. These findings suggest a communication between eosinophils and neutrophils, which may play a role in bronchial asthma. Topics: Asthma; Calcimycin; Cell Communication; Churg-Strauss Syndrome; Eosinophils; Humans; Leukocyte Count; Neutrophils; SRS-A | 1989 |