calca-protein--human and Jaundice--Obstructive

Analysis of the examination and treatment results was conducted in 92 patients, suffering the obturation jaundice syndrome. There was elaborated a diagnostic program, in which the existing diagnostic standard for obturation jaundice and its complicated forms, an acute cholangitis and biliary sepsis, was added by determination of the blood procalcitonin level, microbiological investigation of the blood and bile, the bile microscopy, the analysis of the system inflammatory response syndrome signs and the organs dysfunction (according to SOFA scale). The program introduction have permitted to perform differential diagnosis of uncomplicated--in 30 (32.6%) patients, and complicated--in 42 (45.7%) obturation jaundice in an acute cholangitis and in 20 (21.7%)--in biliary sepsis. The treatment program is characterized by differentiated approach, depending on the disease kind, and includes the conduction of urgent decompression and sanation of biliary ducts. The method and volume of complex conservative therapy have differed essentially in patients, suffering obturation jaundice, an acute cholangitis and biliary sepsis.

Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Bile; Bile Ducts; Calcitonin; Calcitonin Gene-Related Peptide; Cholangitis; Decompression, Surgical; Diagnosis, Differential; Disease Management; Female; Humans; Jaundice, Obstructive; Male; Microscopy; Middle Aged; Minimally Invasive Surgical Procedures; Protein Precursors; Sepsis