calca-protein--human has been researched along with Eclampsia* in 1 studies
1 other study(ies) available for calca-protein--human and Eclampsia
Article | Year |
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Preeclampsia/Eclampsia candidate genes show altered methylation in maternal leukocytes of preeclamptic women at the time of delivery.
To analyze methylation profiles of known preeclampsia/eclampsia (PE) candidate genes in normal (NL) and preeclamptic (PE) women at delivery.. A matched case-control study comparing methylation in 79 CpG sites/33 genes from an independent gene set in maternal leukocyte DNA in PE and NL (n = 14 each) on an Illumina BeadChip platform. Replication performed on second cohort (PE = 12; NL = 32).. PE demonstrates differential methylation in POMC, AGT, CALCA, and DDAH1 compared with NL.. Differential methylation in four genes associated with PE may represent a potential biomarker or an epigenetic pathophysiologic mechanism altering gene transcription. Topics: Adult; Amidohydrolases; Angiotensinogen; Calcitonin Gene-Related Peptide; Case-Control Studies; CpG Islands; DNA Methylation; Eclampsia; Female; Gene Expression Profiling; Humans; Leukocytes; Parturition; Pre-Eclampsia; Pregnancy; Pro-Opiomelanocortin; Young Adult | 2016 |