caffeine has been researched along with Ventricular Dysfunction, Left in 15 studies
Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute ingestion of high doses of caffeine did not induce arrhythmias in patients with systolic heart failure and at high risk for ventricular arrhythmias." | 9.22 | Short-term Effects of High-Dose Caffeine on Cardiac Arrhythmias in Patients With Heart Failure: A Randomized Clinical Trial. ( Chemello, D; Fracasso, B; Giaretta, V; Pimentel, M; Rohde, LE; Salamoni, J; Souza, GC; Zimerman, A; Zimerman, LI; Zuchinali, P, 2016) |
| "Acute ingestion of high doses of caffeine did not induce arrhythmias in patients with systolic heart failure and at high risk for ventricular arrhythmias." | 5.22 | Short-term Effects of High-Dose Caffeine on Cardiac Arrhythmias in Patients With Heart Failure: A Randomized Clinical Trial. ( Chemello, D; Fracasso, B; Giaretta, V; Pimentel, M; Rohde, LE; Salamoni, J; Souza, GC; Zimerman, A; Zimerman, LI; Zuchinali, P, 2016) |
| "Prolonged hyperglycemia was associated with increased chamber dilation, thinning of the left ventricle (LV), and myocyte loss." | 1.46 | Hyperglycemia induces defective Ca2+ homeostasis in cardiomyocytes. ( Anversa, P; Borghetti, G; Cannata, A; Goichberg, P; Hintze, TH; Jacobson, JT; Leri, A; Meo, M; Qanud, K; Rota, M; Signore, S; Sorrentino, A; Zhou, Y, 2017) |
| "Ventricular arrhythmias and contractile dysfunction are the main causes of death in human heart failure (HF)." | 1.31 | Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness. ( Bers, DM; Li, L; Pogwizd, SM; Schlotthauer, K; Yuan, W, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 7 (46.67) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Caldeira, D | 1 |
| Tsai, WC | 1 |
| Lu, YY | 1 |
| Chen, YC | 1 |
| Chang, CJ | 1 |
| Kao, YH | 1 |
| Lin, YK | 1 |
| Chen, YH | 1 |
| Chen, SA | 1 |
| Yang, LY | 1 |
| Chen, YJ | 1 |
| Zuchinali, P | 1 |
| Souza, GC | 1 |
| Pimentel, M | 1 |
| Chemello, D | 1 |
| Zimerman, A | 1 |
| Giaretta, V | 1 |
| Salamoni, J | 1 |
| Fracasso, B | 1 |
| Zimerman, LI | 1 |
| Rohde, LE | 1 |
| Sorrentino, A | 1 |
| Borghetti, G | 1 |
| Zhou, Y | 1 |
| Cannata, A | 1 |
| Meo, M | 1 |
| Signore, S | 1 |
| Anversa, P | 1 |
| Leri, A | 1 |
| Goichberg, P | 1 |
| Qanud, K | 1 |
| Jacobson, JT | 1 |
| Hintze, TH | 1 |
| Rota, M | 1 |
| Sugano, Y | 1 |
| Lai, NC | 1 |
| Gao, MH | 1 |
| Firth, AL | 1 |
| Yuan, JX | 1 |
| Lew, WY | 1 |
| Hammond, HK | 1 |
| Neary, P | 2 |
| Duncan, AM | 2 |
| Cobbe, SM | 2 |
| Smith, GL | 3 |
| Terracciano, CM | 1 |
| Hardy, J | 1 |
| Birks, EJ | 1 |
| Khaghani, A | 1 |
| Banner, NR | 1 |
| Yacoub, MH | 1 |
| Hambarchian, N | 1 |
| Brixius, K | 1 |
| Lu, R | 1 |
| Müller-Ehmsen, J | 1 |
| Schwinger, RH | 1 |
| Belke, DD | 1 |
| Swanson, EA | 1 |
| Dillmann, WH | 1 |
| Currie, S | 1 |
| Quinn, FR | 1 |
| Sayeed, RA | 1 |
| Kettlewell, S | 1 |
| Burkard, N | 1 |
| Rokita, AG | 1 |
| Kaufmann, SG | 1 |
| Hallhuber, M | 1 |
| Wu, R | 1 |
| Hu, K | 1 |
| Hofmann, U | 1 |
| Bonz, A | 1 |
| Frantz, S | 1 |
| Cartwright, EJ | 1 |
| Neyses, L | 1 |
| Maier, LS | 1 |
| Maier, SK | 1 |
| Renné, T | 1 |
| Schuh, K | 1 |
| Ritter, O | 1 |
| Lindner, M | 1 |
| Erdmann, E | 1 |
| Beuckelmann, DJ | 1 |
| Emanuel, K | 1 |
| Mackiewicz, U | 1 |
| Pytkowski, B | 1 |
| Lewartowski, B | 1 |
| Pogwizd, SM | 1 |
| Schlotthauer, K | 1 |
| Li, L | 1 |
| Yuan, W | 1 |
| Bers, DM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of High-dose Caffeine on Cardiac Arrhythmias in Patients With Heart Failure - a Randomized Clinical Trial[NCT02045992] | 112 participants (Anticipated) | Interventional | 2013-04-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for caffeine and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
Short-term Effects of High-Dose Caffeine on Cardiac Arrhythmias in Patients With Heart Failure: A Randomized Clinical Trial.
Topics: Atrial Premature Complexes; Blood Pressure; Caffeine; Central Nervous System Stimulants; Cross-Over | 2016 |
14 other studies available for caffeine and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
Caffeine does not increase the arrhythmic burden in patients with heart failure and left ventricular systolic dysfunction.
Topics: Caffeine; Heart Failure; Humans; Ventricular Dysfunction, Left | 2017 |
Ablation of androgen receptor gene triggers right ventricular outflow tract ventricular tachycardia.
Topics: Action Potentials; Adenosine; Animals; Caffeine; Calcium; Flecainide; Gene Knockdown Techniques; Gen | 2015 |
Hyperglycemia induces defective Ca2+ homeostasis in cardiomyocytes.
Topics: Action Potentials; Animals; Caffeine; Calcium; Central Nervous System Stimulants; Diabetes Mellitus, | 2017 |
Activated expression of cardiac adenylyl cyclase 6 reduces dilation and dysfunction of the pressure-overloaded heart.
Topics: Adenylyl Cyclases; Animals; Caffeine; Calcium; Calcium-Binding Proteins; Dilatation, Pathologic; Enz | 2011 |
Assessment of sarcoplasmic reticulum Ca(2+) flux pathways in cardiomyocytes from rabbits with infarct-induced left-ventricular dysfunction.
Topics: Animals; Biological Transport; Caffeine; Calcium; Calcium-Transporting ATPases; Disease Models, Anim | 2002 |
Clinical recovery from end-stage heart failure using left-ventricular assist device and pharmacological therapy correlates with increased sarcoplasmic reticulum calcium content but not with regression of cellular hypertrophy.
Topics: Caffeine; Calcium; Calcium Channels, L-Type; Calcium Signaling; Cardiovascular Agents; Cell Size; Co | 2004 |
Ouabain increases myofibrillar Ca2+ sensitivity but does not influence the Ca2+ release in human skinned fibres.
Topics: Adult; Caffeine; Calcium; Female; Humans; In Vitro Techniques; Isometric Contraction; Male; Middle A | 2004 |
Decreased sarcoplasmic reticulum activity and contractility in diabetic db/db mouse heart.
Topics: Animals; Caffeine; Calcium; Calcium-Transporting ATPases; Diabetes Mellitus, Type 2; Insulin Resista | 2004 |
Selective down-regulation of sub-endocardial ryanodine receptor expression in a rabbit model of left ventricular dysfunction.
Topics: Animals; Caffeine; Calcium Signaling; Calsequestrin; Disease Models, Animal; Down-Regulation; Endoca | 2005 |
Conditional neuronal nitric oxide synthase overexpression impairs myocardial contractility.
Topics: Animals; Arginine; Caffeine; Calcium; Calcium Channels, L-Type; Calcium Signaling; Cell Size; Cells, | 2007 |
Calcium content of the sarcoplasmic reticulum in isolated ventricular myocytes from patients with terminal heart failure.
Topics: Adult; Caffeine; Calcium; Cardiac Output, Low; Cardiomyopathy, Dilated; Electric Stimulation; Female | 1998 |
Properties of ventricular myocytes isolated from the hypertrophied and failing hearts of spontaneously hypertensive rats.
Topics: Animals; Apoptosis; Caffeine; Calcium; Cell Count; Cell Size; Central Nervous System Stimulants; Ele | 1999 |
Reduced sarcoplasmic reticulum Ca2+ release in rabbits with left ventricular dysfunction.
Topics: Animals; Caffeine; Calcium; Coronary Vessels; Cytosol; In Vitro Techniques; Male; Myocardium; Rabbit | 1998 |
Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Caffeine; Calc | 2001 |