caffeine has been researched along with Retinoblastoma in 1 studies
Retinoblastoma: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Several human heritable cancer-prone syndromes known to alter DNA stability have been found to have defects in checkpoint surveillance pathways." | 2.40 | Cell cycle control, checkpoint mechanisms, and genotoxic stress. ( Kaufmann, WK; Paules, RS; Shackelford, RE, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shackelford, RE | 1 |
| Kaufmann, WK | 1 |
| Paules, RS | 1 |
1 review available for caffeine and Retinoblastoma
| Article | Year |
|---|---|
Cell cycle control, checkpoint mechanisms, and genotoxic stress.
Topics: Animals; Ataxia Telangiectasia; Caffeine; Cell Cycle; Cyclins; DNA Repair; Genes, p53; Humans; Neopl | 1999 |