Page last updated: 2024-10-24

caffeine and Psychoses

caffeine has been researched along with Psychoses in 24 studies

Research Excerpts

ExcerptRelevanceReference
"Clozapine is an atypical antipsychotic drug and displays efficacy in 30% to 60% of patients with schizophrenia who do not respond to traditional antipsychotics."9.09CYP1A2 activity as measured by a caffeine test predicts clozapine and active metabolite steady-state concentrationin patients with schizophrenia. ( Afra, P; Albers, LJ; Collins, EJ; Kalow, W; Kennedy, JL; Ozdemir, V; Posner, P; Reist, C; Roy, R; Tang, BK; Walkes, W, 2001)
"Cigarette smoking and caffeine use are established and problematic drug-use behaviors in people with schizophrenia."7.75Effects of smoking cues on caffeine urges in heavy smokers and caffeine consumers with and without schizophrenia. ( Adolfo, AB; AhnAllen, CG; Tidey, JW, 2009)
"Psychosis-like perceptual distortions can occur in the general population, and both stress and caffeine can enhance the proneness to psychosis-like experiences, such as hallucinations."5.51Stress, caffeine and psychosis-like experiences-A double-blind, placebo-controlled experiment. ( Ágoston, C; Bernáth, L; Demetrovics, Z; Rogers, PJ, 2022)
"Individuals with schizophrenia use twice as much caffeine on average when compared to healthy controls."5.51Alteration of Resting Electroencephalography by Acute Caffeine Consumption in Early Phase Psychosis. ( Anderson, TJ; Fisher, DJ; McKearney, KJ; N Bissonnette, J; Tibbo, PG, 2022)
"Clozapine is an atypical antipsychotic drug and displays efficacy in 30% to 60% of patients with schizophrenia who do not respond to traditional antipsychotics."5.09CYP1A2 activity as measured by a caffeine test predicts clozapine and active metabolite steady-state concentrationin patients with schizophrenia. ( Afra, P; Albers, LJ; Collins, EJ; Kalow, W; Kennedy, JL; Ozdemir, V; Posner, P; Reist, C; Roy, R; Tang, BK; Walkes, W, 2001)
"Caffeine and nicotine are widely used by schizophrenia patients and may worsen psychosis and affect antipsychotic therapies."3.88Nicotine and caffeine modulate haloperidol-induced changes in postsynaptic density transcripts expression: Translational insights in psychosis therapy and treatment resistance. ( Avvisati, L; Buonaguro, EF; de Bartolomeis, A; Iasevoli, F; Latte, G; Marmo, F; Tomasetti, C, 2018)
"Cigarette smoking and caffeine use are established and problematic drug-use behaviors in people with schizophrenia."3.75Effects of smoking cues on caffeine urges in heavy smokers and caffeine consumers with and without schizophrenia. ( Adolfo, AB; AhnAllen, CG; Tidey, JW, 2009)
"Studies of substance use in first episode psychosis patients do not frequently assess non-pathological substance consumption among patients, but rather the prevalence of substance abuse or dependence disorders."1.43Differential effects of sex on substance use between first episode psychosis patients and healthy people. ( Baños, I; Barajas, A; Del Cacho, N; Dolz, M; Huerta-Ramos, E; Núñez, C; Ochoa, S; Sánchez, B; Usall, J, 2016)
" A marked (2 patients) or a moderate (2 patients) improvement of the clinical state of the patients occurred after the increase of CLO blood levels above the therapeutic threshold by the increase of CLO doses to very high values (ie, up to 1400 mg/d) or by the introduction of fluvoxamine, a potent CYP1A2 inhibitor, at low dosage (50 to 100 mg/d)."1.32Nonresponse to clozapine and ultrarapid CYP1A2 activity: clinical data and analysis of CYP1A2 gene. ( Allorge, D; Baumann, P; Bender, S; Broly, F; Cucchia, G; Eap, CB; Jaquenoud Sirot, E; Jonzier-Perey, M, 2004)
"Psychosis frequently occurs in Alzheimer's disease (AD), being associated with more severe cognitive decline, but the underlying mechanisms are unknown."1.32Beta-amyloid treatment sensitizes mice to amphetamine-induced locomotion but reduces response to caffeine. ( da Silva, AL; Dall'Igna, OP; Hoffmann, A; Lara, DR; Souza, DO, 2004)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19907 (29.17)18.7374
1990's2 (8.33)18.2507
2000's7 (29.17)29.6817
2010's5 (20.83)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Ágoston, C1
Bernáth, L1
Rogers, PJ1
Demetrovics, Z1
N Bissonnette, J2
Anderson, TJ2
McKearney, KJ2
Tibbo, PG2
Fisher, DJ2
de Bartolomeis, A1
Iasevoli, F1
Marmo, F1
Buonaguro, EF1
Avvisati, L1
Latte, G1
Tomasetti, C1
Peng, PJ1
Chiang, KT1
Liang, CS1
Golden, LE1
Sassoon, P1
Cáceda, R1
Núñez, C1
Ochoa, S1
Huerta-Ramos, E1
Baños, I1
Barajas, A1
Dolz, M1
Sánchez, B1
Del Cacho, N1
Usall, J1
Adolfo, AB1
AhnAllen, CG1
Tidey, JW1
BARUK, H1
RACINE, M1
Strydom, B1
Bergh, JJ1
Petzer, JP1
Allorge, D2
Chevalier, D1
Lo-Guidice, JM1
Cauffiez, C1
Suard, F1
Baumann, P2
Eap, CB2
Broly, F2
TOCHTERMANN, W1
BONETTI, U1
STOLIAROV, GV1
VOLODARSKAIA, LI1
BUESSOW, H1
de Leon, J2
Bender, S1
Jaquenoud Sirot, E1
Cucchia, G1
Jonzier-Perey, M1
FAHRNI, R1
Dall'Igna, OP1
Hoffmann, A1
da Silva, AL1
Souza, DO1
Lara, DR1
Caykoylu, A1
Ekinci, O1
Kuloglu, M1
Adan, A1
Odom-White, A1
Ozdemir, V1
Kalow, W1
Posner, P1
Collins, EJ1
Kennedy, JL1
Tang, BK1
Albers, LJ1
Reist, C1
Roy, R1
Walkes, W1
Afra, P1
De Freitas, B1
Schwartz, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Impact of Caffeine on Cognition in Schizophrenia[NCT02832401]24 participants (Actual)Interventional2016-09-02Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for caffeine and Psychoses

ArticleYear
Atypical antipsychotic dosing: the effect of smoking and caffeine.
    Psychiatric services (Washington, D.C.), 2004, Volume: 55, Issue:5

    Topics: Antipsychotic Agents; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 CYP1A2; Drug Adm

2004

Trials

4 trials available for caffeine and Psychoses

ArticleYear
Stress, caffeine and psychosis-like experiences-A double-blind, placebo-controlled experiment.
    Human psychopharmacology, 2022, Volume: 37, Issue:3

    Topics: Caffeine; Double-Blind Method; Hallucinations; Humans; Psychotic Disorders; Surveys and Questionnair

2022
Alteration of Resting Electroencephalography by Acute Caffeine Consumption in Early Phase Psychosis.
    Clinical EEG and neuroscience, 2022, Volume: 53, Issue:4

    Topics: Caffeine; Electroencephalography; Humans; Psychotic Disorders; Rest; Schizophrenia

2022
EEG Microstates in Early Phase Psychosis: The Effects of Acute Caffeine Consumption.
    Clinical EEG and neuroscience, 2022, Volume: 53, Issue:4

    Topics: Brain; Brain Mapping; Caffeine; Electroencephalography; Humans; Psychotic Disorders

2022
CYP1A2 activity as measured by a caffeine test predicts clozapine and active metabolite steady-state concentrationin patients with schizophrenia.
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:4

    Topics: Adult; Aged; Antipsychotic Agents; Caffeine; Clozapine; Cytochrome P-450 CYP1A2; Dose-Response Relat

2001

Other Studies

19 other studies available for caffeine and Psychoses

ArticleYear
Nicotine and caffeine modulate haloperidol-induced changes in postsynaptic density transcripts expression: Translational insights in psychosis therapy and treatment resistance.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2018, Volume: 28, Issue:4

    Topics: Animals; Brain; Caffeine; Central Nervous System Agents; Cytoskeletal Proteins; Drug Interactions; D

2018
Low-dose caffeine may exacerbate psychotic symptoms in people with schizophrenia.
    The Journal of neuropsychiatry and clinical neurosciences, 2014, Apr-01, Volume: 26, Issue:2

    Topics: Caffeine; Central Nervous System Stimulants; Humans; Male; Middle Aged; Psychotic Disorders; Schizop

2014
A case report of late onset psychosis with dementia and aspirin and caffeine addiction.
    Schizophrenia research, 2015, Volume: 168, Issue:1-2

    Topics: Age of Onset; Aspirin; Caffeine; Central Nervous System Agents; Dementia; Diagnosis, Differential; H

2015
Differential effects of sex on substance use between first episode psychosis patients and healthy people.
    Comprehensive psychiatry, 2016, Volume: 69

    Topics: Adolescent; Adult; Alcohol Drinking; Caffeine; Cannabis; Comorbidity; Female; Humans; Illicit Drugs;

2016
Effects of smoking cues on caffeine urges in heavy smokers and caffeine consumers with and without schizophrenia.
    Schizophrenia research, 2009, Volume: 107, Issue:2-3

    Topics: Adult; Arousal; Beverages; Caffeine; Comorbidity; Cues; Female; Humans; Male; Middle Aged; Motivatio

2009
Trial of circulatory treatment of early early dementia with folliculin and caffeine (physiological therapeutics or shock therapeutics?).
    Annales medico-psychologiques, 1946, Volume: 104

    Topics: Caffeine; Estrogens; Mental Disorders; Psychotic Disorders; Schizophrenia

1946
8-Aryl- and alkyloxycaffeine analogues as inhibitors of monoamine oxidase.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:8

    Topics: Alkylation; Animals; Binding Sites; Caffeine; Halogens; Humans; Inhibitory Concentration 50; Kinetic

2011
Identification of a novel splice-site mutation in the CYP1A2 gene.
    British journal of clinical pharmacology, 2003, Volume: 56, Issue:3

    Topics: Aged; Base Sequence; Caffeine; Clozapine; Cytochrome P-450 CYP1A2; Exons; Female; Humans; Introns; M

2003
[Critical evaluation of the effect of various drugs in therapy of psychoneurological disorders].
    Medizinische Monatsschrift, 1953, Volume: 7, Issue:6

    Topics: Caffeine; Electroconvulsive Therapy; Humans; Psychosurgery; Psychotherapy; Psychotic Disorders

1953
[Mental disorders caused by analgesic poisoning; description of a case caused by optalidon].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1958, Sep-30, Volume: 82, Issue:3

    Topics: Aminopyrine; Analgesics; Barbiturates; Caffeine; Drug Combinations; Humans; Mental Disorders; Psycho

1958
[On psychic disorders in caffeine poisoning].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1962, Volume: 62

    Topics: Caffeine; Central Nervous System Agents; Humans; Medical Records; Mental Disorders; Psychoses, Subst

1962
[ON THE PROBLEM OF PSYCHOSES DUE TO ANTIASTHMATIC DRUGS].
    Der Nervenarzt, 1964, Volume: 35

    Topics: Anti-Asthmatic Agents; Antipyrine; Asthma; Atropine; Caffeine; Digitalis Glycosides; Ephedrine; Hall

1964
Nonresponse to clozapine and ultrarapid CYP1A2 activity: clinical data and analysis of CYP1A2 gene.
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:2

    Topics: Adult; Antipsychotic Agents; Caffeine; Chromatography, Gas; Clozapine; Cytochrome P-450 CYP1A2; DNA;

2004
[Toxic psychoses due to sedormid, saridon and contra-pain].
    Schweizer Archiv fur Neurologie und Psychiatrie. Archives suisses de neurologie et de psychiatrie. Archivio svizzero di neurologia e psichiatria, 1950, Volume: 65, Issue:1-2

    Topics: Analgesics; Antipyrine; Caffeine; Drug Combinations; Humans; Hypnotics and Sedatives; Pain; Phenacet

1950
Beta-amyloid treatment sensitizes mice to amphetamine-induced locomotion but reduces response to caffeine.
    Neuro-degenerative diseases, 2004, Volume: 1, Issue:1

    Topics: Adenosine; Adrenergic Agents; Alzheimer Disease; Amphetamine; Amyloid beta-Peptides; Animals; Avoida

2004
Improvement from treatment-resistant schizoaffective disorder, manic type after stopping heavy caffeine intake: a case report.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Jul-01, Volume: 32, Issue:5

    Topics: Bipolar Disorder; Caffeine; Central Nervous System Stimulants; Humans; Male; Middle Aged; Psychotic

2008
Chronotype and personality factors in the daily consumption of alcohol and psychostimulants.
    Addiction (Abingdon, England), 1994, Volume: 89, Issue:4

    Topics: Adult; Alcohol Drinking; Caffeine; Circadian Rhythm; Female; Humans; Male; Nicotine; Personality; Pe

1994
Clozapine levels and caffeine.
    The Journal of clinical psychiatry, 1996, Volume: 57, Issue:4

    Topics: Adult; Caffeine; Clozapine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A

1996
Effects of caffeine in chronic psychiatric patients.
    The American journal of psychiatry, 1979, Volume: 136, Issue:10

    Topics: Adult; Bipolar Disorder; Caffeine; Chronic Disease; Humans; Male; Middle Aged; Neurocognitive Disord

1979