caffeine has been researched along with Pregnancy in 1053 studies
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy of occipital nerve block compared with standard care , defined as acetaminophen with caffeine, for treatment of acute headache in pregnancy." | 9.69 | Occipital Nerve Block Compared With Acetaminophen and Caffeine for Headache Treatment in Pregnancy: A Randomized Controlled Trial. ( Blanchard, CT; Bushman, ET; Casey, BM; Cozzi, GD; Davis, AM; Digre, KB; Harper, L; Jones, B; Robbins, LS; Sinkey, RG; Szychowski, JM; Tita, AT, 2023) |
| "Earlier published studies on maternal caffeine intake during pregnancy in relation to the risk of low birth weight (LBW) (birth weight <2500 g) have indicated conflicting findings." | 9.41 | Maternal caffeine consumption during pregnancy and risk of low birth weight: a dose-response meta-analysis of cohort studies. ( Askari, M; Azadbakht, L; Esmaillzadeh, A; Larijani, B; Salari-Moghaddam, A; Saneei, P; Soltani, S, 2023) |
| "This study sought to assess the pharmacokinetic (PK) changes of caffeine and its CYP1A2 metabolites across the 3 trimesters of pregnancy." | 9.22 | Pregnancy-induced changes in the pharmacokinetics of caffeine and its metabolites. ( Campbell, SC; Clark, EA; Schoen, K; Sherwin, CM; Spigarelli, MG; Stockmann, C; Tak, C; Varner, MW; Yu, T, 2016) |
| "To evaluate the effectiveness and safety of different doses of caffeine in treatment of primary apnea in preterm infants." | 9.22 | [Clinical effectiveness of different doses of caffeine for primary apnea in preterm infants]. ( Liu, G; Tian, X; Zhao, Y, 2016) |
| "The potential effect of caffeine exposure during pregnancy on gestational hypertension (GH)/preeclampsia has attracted attention but remains unclear." | 9.22 | The association between caffeine exposure during pregnancy and risk of gestational hypertension/preeclampsia: A meta-analysis and systematical review. ( Chen, B; He, Y; Hong, J; Jiang, K; Ni, S; Shen, J; Shi, Y; Si, Y; Zhang, M, 2022) |
| "To estimate the effect of reducing caffeine intake during pregnancy on birth weight and length of gestation." | 9.12 | Effect of reducing caffeine intake on birth weight and length of gestation: randomised controlled trial. ( Bech, BH; Henriksen, TB; Obel, C; Olsen, J, 2007) |
| "Database searches using terms linking caffeine and caffeinated beverages to pregnancy outcomes identified 1261 English language peer-reviewed articles." | 9.12 | Maternal caffeine consumption and pregnancy outcomes: a narrative review with implications for advice to mothers and mothers-to-be. ( James, JE, 2021) |
| "Forty postpartum patients with postdural puncture headache (PDPH) were randomly assigned to receive oral caffeine (300 mg) or a placebo." | 9.06 | Effects of oral caffeine on postdural puncture headache. A double-blind, placebo-controlled trial. ( Camann, WR; Lambert, DH; Murray, RS; Mushlin, PS, 1990) |
| "In a double-blind, randomized controlled trial among 500 post-partum patients experiencing moderate to severe pain, a single oral dose of an aspirin/caffeine combination (800 mg aspirin, 65 mg caffeine) provided significantly more pain relief at 2 hours than did a higher dose of an acetaminophen/aspirin combination (648 mg acetaminophen, 648 mg aspirin) and a higher dose of acetaminophen alone (1000 mg acetaminophen)." | 9.05 | A double-blind randomized study of an aspirin/caffeine combination versus acetaminophen/aspirin combination versus acetaminophen versus placebo in patients with moderate to severe post-partum pain. ( Rubin, A; Winter, L, 1984) |
| "Epidemiological studies have revealed that caffeine consumption during pregnancy is associated with adverse gestational outcomes, yet the underlying mechanisms remain obscure." | 9.05 | Impacts of Caffeine during Pregnancy. ( Chen, Q; Duan, E; Qian, J; Ward, SM; Zhang, Y, 2020) |
| "Caffeine reduces the risk of bronchopulmonary dysplasia (BPD)." | 8.98 | Optimizing Caffeine Use and Risk of Bronchopulmonary Dysplasia in Preterm Infants: A Systematic Review, Meta-analysis, and Application of Grading of Recommendations Assessment, Development, and Evaluation Methodology. ( Pakvasa, MA; Patel, RM; Saroha, V, 2018) |
| "To provide a narrative synthesis of recently published studies on caffeine use as a risk or protective factor for health outcomes, with a focus on women's health and pregnancy." | 8.95 | A review of caffeine use as a risk or protective factor for women's health and pregnancy. ( Bruno, R; Mattick, RP; Peacock, A, 2017) |
| "To assess the association between maternal caffeine intake and risk of pregnancy loss using a systematic review and meta-analysis." | 8.93 | Maternal caffeine intake during pregnancy and risk of pregnancy loss: a categorical and dose-response meta-analysis of prospective studies. ( Chen, LW; Chong, MF; Neelakantan, N; Pan, A; van Dam, RM; Wu, Y, 2016) |
| " Reducing caffeinated coffee consumption by 180 mg of caffeine (the equivalent of 2 cups) per day after 16 weeks' gestation doesn't affect birth weight." | 8.93 | Clinical Inquiry: Does caffeine intake during pregnancy affect birth weight? ( Adams, T; Kelsberg, G; Safranek, S, 2016) |
| "This aim of this study was to conduct a systematic literature review on the association between maternal caffeine intake during pregnancy and attention deficit hyperactivity disorder (ADHD) in childhood." | 8.91 | [Caffeine consumption during pregnancy and attention deficit hyperactivity disorder (ADHD): a systematic literature review]. ( Anselmi, L; Santos, IS; Schmidt, V; Silva, Bdel P, 2015) |
| "Previous reports of the relationship between pregnancy loss and caffeine/coffee consumption have been inconsistent." | 8.91 | A meta-analysis of risk of pregnancy loss and caffeine and coffee consumption during pregnancy. ( Li, J; Song, JM; Tang, YL; Xin, CM; Zhang, J; Zhao, H, 2015) |
| "Maternal caffeine consumption during pregnancy may have adverse effects on fetal, neonatal and maternal outcomes." | 8.91 | Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcomes. ( Jaafar, SH; Jahanfar, S, 2015) |
| "Epidemiologic studies have shown inconsistent conclusions about the effect of caffeine intake during pregnancy on the risk of low birth weight (LBW)." | 8.91 | Maternal Caffeine Consumption during Pregnancy and Risk of Low Birth Weight: A Dose-Response Meta-Analysis of Observational Studies. ( Keum, N; Kim, R; Kim, Y; Lai, Y; Oldenburg, CE; Rhee, J; Tam, M, 2015) |
| "Caffeine is commonly consumed during pregnancy, crosses the placenta, with fetal serum concentrations similar to the mother's, but studies of birth outcome show conflicting findings." | 8.90 | Caffeine intake during pregnancy and adverse birth outcomes: a systematic review and dose-response meta-analysis. ( Cade, JE; Garrard, L; Greenwood, DC; Keogh, G; King, LG; Thatcher, NJ; Ye, J, 2014) |
| "Considerable controversy exists regarding the relation between maternal caffeine intake during pregnancy and risk of low birth weight (birth weight <2,500 g)." | 8.90 | Maternal caffeine intake during pregnancy is associated with risk of low birth weight: a systematic review and dose-response meta-analysis. ( Chen, LW; Chong, MF; Neelakantan, N; Pan, A; van Dam, RM; Wu, Y, 2014) |
| " The earlier review included 20 studies (7238 participants) in valid comparisons, but because we used different outcomes for some headache studies, the number of participants in the analyses of the effects of caffeine is now 4262 when previously it was 5243." | 8.90 | Caffeine as an analgesic adjuvant for acute pain in adults. ( Derry, CJ; Derry, S; Moore, RA, 2014) |
| "Compounds other than macronutrients have been shown to influence blood glucose concentrations and insulin sensitivity in people with diabetes, with caffeine being one such substance." | 8.89 | Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus. ( White, H; Whitehead, N, 2013) |
| "Maternal caffeine consumption during pregnancy may have adverse effects on fetal, neonatal and maternal outcomes." | 8.89 | Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcome. ( Jaafar, SH; Jahanfar, S, 2013) |
| " Most studies used paracetamol or ibuprofen, with 100 mg to 130 mg caffeine, and the most common pain conditions studied were postoperative dental pain, postpartum pain, and headache." | 8.88 | Caffeine as an analgesic adjuvant for acute pain in adults. ( Derry, CJ; Derry, S; Moore, RA, 2012) |
| "We performed a meta-analysis examining the association between caffeine consumption during pregnancy and risk of preterm birth." | 8.86 | Caffeine consumption during pregnancy and risk of preterm birth: a meta-analysis. ( Bhattacharya, S; Lin, SW; Maslova, E; Michels, KB, 2010) |
| "Maternal caffeine consumption during pregnancy may have adverse effects on fetal, neonatal and maternal outcomes." | 8.85 | Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcome. ( Jahanfar, S; Sharifah, H, 2009) |
| "Maternal use of "social drugs" such as caffeine, ethanol and tobacco in pregnancy is on increase- -worldwide." | 8.85 | Peripartum implications of caffeine intake in pregnancy: is there cause for concern? ( Kuczkowski, KM, 2009) |
| "This article reports on a systematic review of studies on caffeine intake during pregnancy and prevalence of low birth weight and prematurity, focusing on methods to quantify intake and control for confounding." | 8.84 | [Caffeine consumption during pregnancy and prevalence of low birth weight and prematurity: a systematic review]. ( Barreiros, NS; Kac, G; Pacheco, AH; Santos, IS, 2007) |
| "To review the methodologic issues complicating caffeine exposure assessment during pregnancy; to discuss maternal and fetal caffeine metabolism, including genetic polymorphisms affecting caffeine metabolism; and to discuss the endogenous and exogenous risk factors known to influence caffeine metabolism." | 8.82 | Caffeine metabolism, genetics, and perinatal outcomes: a review of exposure assessment considerations during pregnancy. ( Bracken, MB; Grosso, LM, 2005) |
| "Caffeine's metabolism, mechanisms of action and effects on pregnancy outcome in laboratory animals and humans have been studied extensively." | 8.77 | Effects of caffeine consumption on pregnancy outcome. A review. ( Berger, A, 1988) |
| "Caffeine is a widely consumed substance, and there is a discussion about its effects when ingested by women during pregnancy and lactation." | 8.31 | Genotoxic effects of caffeine in female mice exposed during pregnancy and lactation period and their offspring. ( Bahia Franca, I; Da Silva, J; Lummertz Magenis, M; Martins Longaretti, L; Moraes de Andrade, V; Paganini Damiani, A; Ricardo Cantareli da Silva, A; Rodrigues Boeck, C; Souza de Marcos, P, 2023) |
| "Our previous study reported that prenatal caffeine exposure (PCE) could induce chondrodysplasia and increase the susceptibility to osteoarthritis in offspring rats." | 8.12 | Intrauterine programming of cartilaginous 11β-HSD2 induced by corticosterone and caffeine mediated susceptibility to adult osteoarthritis. ( Chen, L; Gao, H; He, H; Li, B; Magdaloud, J; Shi, H; Wang, H; Wu, Z, 2022) |
| "This study examined the association between mothers' estimated caffeine intake during pregnancy and their children's score on the Japanese version of the Ages & Stages Questionnaires™ (J-ASQ) at 6 and 12 months of age." | 8.12 | Association between maternal caffeine intake during pregnancy and child development at 6 and 12 months: The Japan Environment and Children's Study. ( Bamai, YA; Ikeda-Araki, A; Ito, Y; Itoh, M; Itoh, S; Kishi, R; Kobayashi, S; Masuda, H; Miyashita, C; Nishihara, S; Saijo, Y; Tamura, N; Yamazaki, K, 2022) |
| " Among the external factors, chemical compounds stand out, which include caffeine, since its consumption is common among women, including during pregnancy." | 8.12 | Behavioral, genetic and biochemical changes in the brain of the offspring of female mice treated with caffeine during pregnancy and lactation. ( Boeck, CR; Borges Correa, MEA; Budni, J; Damiani, AP; de Andrade, VM; de Bem Silveira, G; de Marcos, PS; Effting, PS; Franca, IB; Magenis, ML; Medeiros, EB; Muller, AP; Silveira, PCL, 2022) |
| "Greater caffeine consumption in pregnancy is associated with reduced birth size, but potential associations with childhood growth are unclear." | 8.12 | Association of Maternal Caffeine Consumption During Pregnancy With Child Growth. ( Gilman, SE; Gleason, JL; Grantz, KL; Grobman, WA; Hinkle, SN; Hunt, KJ; Kannan, K; Mitro, SD; Nageotte, M; Newman, RB; Robinson, M; Skupski, DW; Sundaram, R; Zhang, C, 2022) |
| "Low to moderate caffeine consumption during pregnancy was not associated with any persistent adverse effects concerning the child's neurodevelopment up to 8 years of age." | 8.02 | Maternal caffeine intake during pregnancy and child neurodevelopment up to eight years of age-Results from the Norwegian Mother, Father and Child Cohort Study. ( Berglundh, S; Brandlistuen, R; Brantsæter, AL; Jacobsson, B; Sengpiel, V; Solé-Navais, P; Vollrath, M, 2021) |
| "To examine the association between maternal caffeine intake during pregnancy and the development of food allergy in young Japanese children up to 3 years of age." | 8.02 | Maternal caffeine intake during pregnancy and risk of food allergy in young Japanese children. ( Arakawa, M; Miyake, Y; Okubo, H; Sasaki, S; Tanaka, K, 2021) |
| "To determine whether caffeinated-beverage intake and plasma caffeine and paraxanthine are associated with cardiometabolic complications in pregnancy (ie, gestational diabetes [GDM], preeclampsia, and gestational hypertension [GH])." | 8.02 | Assessment of Caffeine Consumption and Maternal Cardiometabolic Pregnancy Complications. ( Gleason, JL; Grantz, KL; Grewal, J; Hinkle, SN; Mumford, SL; Sundaram, R; Yisahak, SF; Zhang, C; Zhao, SK, 2021) |
| "Our previous studies confirmed that prenatal caffeine exposure (PCE) could induce susceptibility to osteoarthritis in adult offspring rats due to poor chondrocyte differentiation, but its mechanism remains to be further investigated." | 7.96 | Subchondral bone dysplasia mediates susceptibility to osteoarthritis in female adult offspring rats induced by prenatal caffeine exposure. ( Chen, L; Magdalou, J; Tan, Y; Wang, H; Wen, Y; Xiao, H; Xie, X, 2020) |
| "Maternal caffeine intake during pregnancy is associated with an increased risk of childhood obesity." | 7.96 | Associations of maternal caffeine intake during pregnancy with abdominal and liver fat deposition in childhood. ( Gaillard, R; Hulst, ME; Jaddoe, VW; Oei, EH; Voerman, E, 2020) |
| "The use of excessive caffeine and consumption of alcohol, cigarette, and khat during pregnancy can result in adverse health effects on the fetus." | 7.96 | Caffeine, alcohol, khat, and tobacco use during pregnancy in Butajira, South Central Ethiopia. ( Alamneh, AA; Endris, BS; Gebreyesus, SH, 2020) |
| "This study aimed to evaluate female adult offspring induced by prenatal caffeine exposure (PCE) are susceptible to non-alcoholic fatty liver disease (NAFLD) and to explore the underlying programming mechanisms." | 7.91 | Prenatal caffeine exposure increases the susceptibility to non-alcoholic fatty liver disease in female offspring rats via activation of GR-C/EBPα-SIRT1 pathway. ( Hu, S; Luo, H; Wang, H; Xia, L; Xu, D; Xu, Y; Yu, H, 2019) |
| "Caffeine is a psychoactive substance that may affect the normal course of pregnancy, therefore its intake during that time should not exceed 200 mg/day." | 7.91 | Caffeine Intake During Pregnancy and Neonatal Anthropometric Parameters. ( Jarosz, M; Wierzejska, R; Wojda, B, 2019) |
| "Few previous studies have investigated the association between prenatal caffeine intake and birth size (small for gestational age [SGA], preterm birth, and birthweight Z-score) in Japan." | 7.91 | Dose-dependent associations between prenatal caffeine consumption and small for gestational age, preterm birth, and reduced birthweight in the Japan Environment and Children's Study. ( Ait Bamai, Y; Araki, A; Itoh, S; Kishi, R; Kobayashi, S; Minatoya, M; Miyashita, C; Murata, K; Saijo, Y; Sata, F; Yamazaki, K, 2019) |
| "In addition to the pharmacological antagonism of adenosine receptors, caffeine appears to be a potent antioxidant and modulates the hyperoxia-induced pulmonary oxidative stress response and thus protective properties in the BPD-associated animal model." | 7.91 | Antioxidative effects of caffeine in a hyperoxia-based rat model of bronchopulmonary dysplasia. ( Bührer, C; Endesfelder, S; Scheuer, T; Schmitz, T; Strauß, E, 2019) |
| "Maternal antenatal, but not paternal or grandparental, caffeine intake is associated with higher offspring adiposity and obesity risk at age 5 and 9 y, with stronger associations observed for coffee caffeine." | 7.91 | Maternal, but not paternal or grandparental, caffeine intake is associated with childhood obesity and adiposity: The Lifeways Cross-Generation Cohort Study. ( Chen, LW; Kelleher, CC; Mehegan, J; Murrin, CM; Phillips, CM, 2019) |
| "To investigate the relation between pre-pregnancy caffeine and caffeinated beverage intake and risk of spontaneous abortion (SAB)." | 7.88 | Pre-pregnancy caffeine and caffeinated beverage intake and risk of spontaneous abortion. ( Chavarro, JE; Gaskins, AJ; Missmer, SA; Rich-Edwards, JW; Toth, TL; Williams, PL, 2018) |
| "The aims of this study were to identify: (i) the proportion of women exceeding the caffeine intake guideline (>200 mg/day) during each trimester, accounting for point of pregnancy awareness; (ii) guideline adherence trajectories across pregnancy; (iii) maternal characteristics associated with trajectories; and (iv) association between adherence and growth restriction birth outcomes." | 7.88 | Adherence to the Caffeine Intake Guideline during Pregnancy and Birth Outcomes: A Prospective Cohort Study. ( Allsop, S; Bruno, R; Burns, L; Elliott, E; Hutchinson, D; Mattick, RP; McCormack, C; Olsson, CA; Peacock, A; Wilson, J, 2018) |
| "To study the association between maternal caffeine intake during pregnancy and the child's weight gain and overweight risk up to 8 years." | 7.88 | Maternal caffeine intake during pregnancy and childhood growth and overweight: results from a large Norwegian prospective observational cohort study. ( Alexander, J; Bacelis, J; Botton, J; Brantsæter, AL; Elfvin, A; Haugen, M; Jacobsson, B; Meltzer, HM; Papadopoulou, E; Sengpiel, V, 2018) |
| "Twenty-four adult Wistar rats were randomly assigned to four groups, with one control group and three groups being treated with caffeine at doses of 25, 50 and 100 mg/kg throughout pregnancy." | 7.88 | Nonlinear effects of caffeine on the viability, synthesis and gene expression of chondrocytes from the offspring of rats treated during pregnancy. ( da Silva, AP; de Melo Ocarino, N; de Paula, IHF; Oliveira, KP; Reis, AMS; Serakides, R; Tarragô, JF, 2018) |
| "Our previous in vivo studies showed that prenatal caffeine exposure (PCE) could restrain the development of chondrogenesis, which may delay fetal articular cartilage development and increase susceptibility to osteoarthritis in adults." | 7.88 | Prenatal caffeine exprosure increases adult female offspring rat's susceptibility to osteoarthritis via low-functional programming of cartilage IGF-1 with histone acetylation. ( Chen, L; Li, J; Lu, K; Magdalou, J; Ni, Q; Tan, Y; Wang, H; Zhao, Z, 2018) |
| "Epidemiologic investigations suggest that excessive intake of caffeine during pregnancy is one of the risk factors for osteoporosis in adult offspring." | 7.88 | Intrauterine Programming of Glucocorticoid-Insulin-Like Growth Factor-1 Axis-Mediated Developmental Origin of Osteoporosis Susceptibility in Female Offspring Rats with Prenatal Caffeine Exposure. ( Chen, L; Jiang, H; Magdalou, J; Qin, J; Shangguan, Y; Tan, Y; Wang, H; Wen, Y, 2018) |
| " To describe caffeine consumption during pregnancy and its association with low birth weight (LBW) and preterm birth in the birth cohort of Ribeirão Preto, state of São Paulo, Brazil, in 2010." | 7.88 | Association between Caffeine Consumption in Pregnancy and Low Birth Weight and Preterm Birth in the birth Cohort of Ribeirão Preto. ( Batista, RFL; Cardoso, VC; Cavalli, RC; Grandi, C; Simões, VMF; Vitti, FP, 2018) |
| "Objective To investigate the association between maternal caffeine intake during pregnancy and infant anthropometric measurements at age 3 and 6 months." | 7.85 | Caffeine Intake During Pregnancy in Different Intrauterine Environments and its Association with Infant Anthropometric Measurements at 3 and 6 Months of Age. ( Bernardi, JR; Bosa, VL; da Silva, CH; de Brito, ML; de Medeiros, TS; Goldani, MZ, 2017) |
| "We examined the association of hypospadias risk with maternal smoking and consumption of alcohol and caffeine." | 7.85 | Maternal Smoking, Alcohol, and Caffeine Exposures and Risk of Hypospadias. ( Carmichael, SL; Ma, C; Shaw, GM, 2017) |
| "To examine the association between maternal caffeine consumption from coffee and tea during pregnancy and offspring behavioral disorders." | 7.85 | Maternal Caffeine Consumption during Pregnancy and Behavioral Disorders in 11-Year-Old Offspring: A Danish National Birth Cohort Study. ( Bech, BH; Hvolgaard Mikkelsen, S; Niclasen, J; Obel, C; Olsen, J, 2017) |
| "This study aimed to investigate the association between prenatal caffeine ingestion (PCI) and risk of postnatal pulmonary inflammation." | 7.85 | Prenatal caffeine ingestion increases susceptibility to pulmonary inflammation in adult female rat offspring. ( Chen, T; Hou, LF; Liu, HX; Liu, S; Ping, J; Qu, W; Wen, X; Yan, HY, 2017) |
| "Apnea of prematurity (AOP) is nearly universal among very preterm infants, but neither the apnea burden nor its clinical associations have been systematically studied in a large consecutive cohort." | 7.83 | Clinical associations of immature breathing in preterm infants: part 1-central apnea. ( Delos, J; Fairchild, K; Kattwinkel, J; Lake, D; Mohr, M; Moorman, JR; Paget-Brown, A; Tabacaru, C, 2016) |
| "The associations of maternal caffeine intake during pregnancy with offspring growth patterns and body fat and insulin levels at school age were examined." | 7.83 | Maternal caffeine intake during pregnancy, early growth, and body fat distribution at school age. ( Franco, OH; Gaillard, R; Gishti, O; Hofman, A; Jaddoe, VW; Voerman, E, 2016) |
| "Postnatal administration of caffeine may reduce the risk of cerebral palsy (CP) in vulnerable low-birth-weight neonates." | 7.83 | Intake of Caffeinated Soft Drinks before and during Pregnancy, but Not Total Caffeine Intake, Is Associated with Increased Cerebral Palsy Risk in the Norwegian Mother and Child Cohort Study. ( Brantsæter, AL; Eichelberger, KY; Lie, RT; Meltzer, HM; Moster, D; Stoltenberg, C; Strandberg-Larsen, K; Tollånes, MC; Wilcox, AJ, 2016) |
| "Studies evaluating caffeine intake during pregnancy and long-term outcomes, such as the child's neurobehaviour, are still scarce and their results are inconsistent." | 7.83 | Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study. ( Anselmi, L; Del-Ponte, B; Matijasevich, A; Munhoz, TN; Santos, IS; Tovo-Rodrigues, L, 2016) |
| "Twenty-four adult Wistar rats were randomly divided into four groups, consisting of one control group and three groups that were treated with 25, 50, or 100 mg/kg of caffeine by an oral-gastric probe throughout the duration of the experimental period (pregnancy)." | 7.81 | Osteogenic potential of osteoblasts from neonatal rats born to mothers treated with caffeine throughout pregnancy. ( Goes, AM; Ocarino, Nde M; Reis, AM; Ribeiro, LG; Serakides, R, 2015) |
| "Prenatal caffeine exposure (PCE) alters the hypothalamic-pituitary-adrenocortical (HPA) axis-associated neuroendocrine metabolic programming and induces an increased susceptibility to metabolic syndrome (MS) in intrauterine growth retardation (IUGR) offspring rats." | 7.81 | Gender-specific increase in susceptibility to metabolic syndrome of offspring rats after prenatal caffeine exposure with post-weaning high-fat diet. ( Chen, L; Guo, Y; He, Z; Li, J; Luo, H; Ma, L; Magdalou, J; Wang, H; Wu, Y; Zhang, L, 2015) |
| "Although caffeine is commonly consumed during pregnancy, there are few reports on the association of in utero caffeine exposure with offspring cognition or behavior during childhood." | 7.81 | Maternal Caffeine Intake During Pregnancy and Child Cognition and Behavior at 4 and 7 Years of Age. ( Keim, SA; Klebanoff, MA, 2015) |
| "there was no difference in caffeine consumption in pregnant women with birth weight ≥2 500 g and." | 7.81 | PERINATAL OUTCOMES OF PREMATURITY AND BIRTH WEIGHT ACCORDING TO MATERNAL CAFFEINE CONSUMPTION. ( Bueno-Cavanillas, A; Del Castillo, N; Jiménez-Moleón, JJ; Martínez-Ruiz, V; Mozas, J; Olmedo-Requena, R, 2015) |
| "To determine if an early commencement of caffeine is associated with improved survival without bronchopulmonary dysplasia (BPD) in preterm infants." | 7.80 | Early caffeine therapy for prevention of bronchopulmonary dysplasia in preterm infants. ( Aghai, ZH; Dysart, KC; Genen, L; Greenspan, JS; Kirkby, S; Nawab, U; Taha, D, 2014) |
| "We describe patterns of dietary caffeine consumption before and after pregnancy recognition in a cohort of women who recently gave birth." | 7.80 | Exploring maternal patterns of dietary caffeine consumption before conception and during pregnancy. ( Bell, EM; Browne, ML; Chen, L; Druschel, CM; Romitti, PA, 2014) |
| "We hypothesized that caffeine improves respiratory function via an anti-inflammatory effect in lungs of a lipopolysaccharide (LPS)-induced pro-inflammatory amnionitis rat pup model." | 7.80 | Anti-inflammatory effect of caffeine is associated with improved lung function after lipopolysaccharide-induced amnionitis. ( Balan, KV; Jafri, A; Kc, P; Köroğlu, OA; MacFarlane, PM; Martin, RJ; Zenebe, WJ, 2014) |
| "The aim of this study was to explore the relationships between nausea and vomiting in pregnancy and (a) fetal growth restriction; and (b) maternal caffeine metabolism and fetal growth restriction." | 7.79 | Does nausea and vomiting of pregnancy play a role in the association found between maternal caffeine intake and fetal growth restriction? ( Alwan, N; Boylan, SM; Cade, JE; Cooke, MS; Dolby, VA; Greenwood, DC; Hay, AW; Kirk, SF; Konje, JC; Potdar, N; Shires, S; Simpson, NA; Taub, N; Thomas, JD; Walker, JJ; White, KL; Wild, CP, 2013) |
| "There are conflicting data on the fetal safety of dietary caffeine consumption during pregnancy, particularly at levels of 300 mg/d or greater." | 7.79 | Is caffeine consumption safe during pregnancy? ( Bozzo, P; Koren, G; Morgan, S, 2013) |
| "Estimation of the maternal caffeine intake during pregnancy and its influence on pregnancy duration, birthweight and Apgar score of the newborn." | 7.78 | Maternal caffeine intake and its effect on pregnancy outcomes. ( Jarosz, M; Siuba, M; Wierzejska, R, 2012) |
| " Results suggest an additive negative effect of maternal caffeine on the fetal CV response to acute maternal hypoxia, potentially mediated via adenosine A(2A) receptor inhibition during primary cardiovascular morphogenesis." | 7.78 | Maternal hypoxia and caffeine exposure depress fetal cardiovascular function during primary organogenesis. ( Keller, BB; Momoi, N; Tinney, JP; Tobita, K, 2012) |
| "Human studies that have investigated the association between caffeine intake during pregnancy and offspring's behavioral outcomes are scant and inconclusive." | 7.78 | Caffeine intake during pregnancy and risk of problem behavior in 5- to 6-year-old children. ( Hofland, L; Koot, HM; Loomans, EM; Van den Bergh, BR; van der Stelt, O; van der Wal, MF; Vrijkotte, TG, 2012) |
| "Caffeine intake has been suggested to be associated with the risk of hypertension." | 7.77 | Maternal caffeine intake, blood pressure, and the risk of hypertensive complications during pregnancy. The Generation R Study. ( Bakker, R; Hofman, A; Jaddoe, VW; Raat, H; Steegers, EA, 2011) |
| "Outside pregnancy, acute caffeine consumption is associated with insulin resistance." | 7.77 | Caffeine and insulin resistance in pregnancy. ( Catov, J; Laughon, SK; Parana, S; Powers, RW; Roberts, JM, 2011) |
| "Caffeine is a commonly consumed drug during pregnancy with the potential to affect the developing fetus." | 7.76 | Caffeine intake during pregnancy, late miscarriage and stillbirth. ( Alwan, N; Boylan, S; Cade, JE; Charvill, J; Chipps, KC; Cooke, MS; Dolby, VA; Greenwood, DC; Hay, AW; Kassam, S; Kirk, SF; Konje, JC; Potdar, N; Shires, S; Simpson, N; Taub, N; Thomas, JD; Walker, J; White, KL; Wild, CP, 2010) |
| "Investigations of maternal caffeine intake and neural tube defects (NTDs) have not considered genetic influences." | 7.76 | Caffeine, selected metabolic gene variants, and risk for neural tube defects. ( Browne, ML; Burns, TL; Druschel, CM; Murray, JC; Olney, RS; Romitti, PA; Schmidt, RJ, 2010) |
| "Moderate caffeine consumption (less than 200 mg per day) does not appear to be a major contributing factor in miscarriage or preterm birth." | 7.76 | ACOG CommitteeOpinion No. 462: Moderate caffeine consumption during pregnancy. ( , 2010) |
| "To determine effects of 2 doses of caffeine on metabolic variables in neonatal pigs with peripartum asphyxia." | 7.76 | Effects of administration of caffeine on metabolic variables in neonatal pigs with peripartum asphyxia. ( Becerril-Herrera, M; Bonilla-Jaime, H; Hernández-González, R; Mota-Rojas, D; Orozco-Gregorio, H; Trujillo-Ortega, ME; Villanueva-García, D, 2010) |
| "This study evaluated the effect of caffeine consumption on the success rate of pregnancy and various in vitro fertilization (IVF) performance parameters." | 7.76 | The effect of caffeine consumption on the success rate of pregnancy as well various performance parameters of in-vitro fertilization treatment. ( Al-Saleh, I; Coskun, S; El-Doush, I; Grisellhi, B, 2010) |
| "The aim of this analysis of the study 'Breast-feeding habits in Bavaria' is to describe the smoking habits, alcohol and caffeine consumption of mothers in Bavaria before, during and after pregnancy." | 7.75 | [Smoking, alcohol and caffeine consumption of mothers before, during and after pregnancy--results of the study 'breast-feeding habits in Bavaria']. ( Fromme, H; Kohlhuber, M; Koletzko, B; Rebhan, B; Schwegler, U, 2009) |
| "Moderate caffeine intake during pregnancy is common, but little is known about its potential association with birth defects." | 7.75 | Maternal caffeine intake during pregnancy and orofacial clefts. ( Browne, ML; Collier, SA; Honein, MA; Rasmussen, SA, 2009) |
| "Associations between maternal caffeine consumption and neural tube defects (NTDs) by type of NTD (anencephaly, spina bifida, or encephalocele) were examined using data from the National Birth Defects Prevention Study (NBDPS)." | 7.75 | Maternal caffeine consumption and risk of neural tube defects. ( Browne, ML; Burns, TL; Druschel, CM; Olney, RS; Romitti, PA; Schmidt, RJ, 2009) |
| "In Denmark chlorobutanol-caffeine rectal suppositories are prescribed by some obstetric departments for the treatment of hyperemesis gravidarum." | 7.74 | [The treatment of hyperemesis gravidarum with chlorobutanol-caffeine rectal suppositories in Denmark: practice and evidence]. ( Brødbaek, HB; Damkier, P, 2007) |
| "The objective of the study was to examine whether the risk of miscarriage is associated with caffeine consumption during pregnancy after controlling for pregnancy-related symptoms." | 7.74 | Maternal caffeine consumption during pregnancy and the risk of miscarriage: a prospective cohort study. ( Li, DK; Odouli, R; Weng, X, 2008) |
| "To examine the association of maternal caffeine intake with fetal growth restriction." | 7.74 | Maternal caffeine intake during pregnancy and risk of fetal growth restriction: a large prospective observational study. ( , 2008) |
| "The aim of this work was to study whether caffeine or theophylline chronically consumed during pregnancy affect inhibitory adenylyl cyclase pathway mediated by adenosine, in rat brain of both mothers and full-term fetuses." | 7.73 | Chronic caffeine or theophylline intake during pregnancy inhibits A1 receptor function in the rat brain. ( Albasanz, JL; León, D; Martín, M; Ruíz, MA, 2005) |
| "Some case-control studies have demonstrated that caffeine intake and high CYP1A2 activity increase risks of recurrent pregnancy loss (RPL) but the multifactorial effect is obscure." | 7.73 | Caffeine intake, CYP1A2 polymorphism and the risk of recurrent pregnancy loss. ( Kato, EH; Kishi, R; Minakami, H; Morikawa, M; Saijo, Y; Sata, F; Suzuki, K; Yamada, H, 2005) |
| "The purpose of the study was to examine whether caffeine dependence and a family history of alcoholism are associated with continued use of caffeine during pregnancy." | 7.73 | Caffeine dependence in combination with a family history of alcoholism as a predictor of continued use of caffeine during pregnancy. ( Berger, N; Griffiths, RR; Haug, NA; Svikis, DS, 2005) |
| "The objective of this study was to examine the association between caffeine intake during pregnancy and fetal mortality in Montevideo, the capital city of Uruguay, taking into account several potential confounding factors." | 7.73 | Maternal caffeine consumption and fetal death: a case-control study in Uruguay. ( Barros, FC; Matijasevich, A; Santos, IS; Yemini, A, 2006) |
| "Apnea of prematurity develop during the first days of life and usually resolve by the time the infant reaches 36-37 weeks postmenstrual age." | 7.73 | [Apnea of prematurity: risk factors and ambulatory treatment with caffeine citrate]. ( Baudon, JJ; Biran-Mucignat, V; Boelle, PY; Ducrocq, S; Gold, F; Lebas, F, 2006) |
| "The aim of this study was to determine the effects of tobacco use and consumption of caffeine in pregnancy on the fetus and placenta by measuring the body weights, head circumferences, and lengths of newborns, and also weights and diameters of placentas." | 7.72 | The effect of smoking and caffeine on the fetus and placenta in pregnancy. ( Balat, A; Balat, O; Pençe, S; Ugur, MG, 2003) |
| "Evidence for a harmful effect of caffeine intake on risk of miscarriage (spontaneous abortion) is inconsistent and nausea during pregnancy has been claimed to explain any association seen." | 7.72 | The effect of caffeine consumption and nausea on the risk of miscarriage. ( Doyle, P; Giannelli, M; Hermon, C; Pelerin, M; Roman, E, 2003) |
| "It has been suggested that a high caffeine intake in pregnancy may be a risk factor for fetal growth retardation." | 7.72 | High caffeine consumption in the third trimester of pregnancy: gender-specific effects on fetal growth. ( Bakketeig, LS; Jacobsen, G; Lund-Larsen, K; Trygg, KU; Vik, T, 2003) |
| "Consumption of caffeine and alcohol is suspected to affect pregnancy outcome." | 7.72 | Does caffeine and alcohol intake before pregnancy predict the occurrence of spontaneous abortion? ( Bergholt, T; Grønbaek, M; Kjaer, SK; Madsen, LB; Munk, C; Ottesen, B; Tolstrup, JS, 2003) |
| "To test the hypothesis that, in women with type 1 diabetes, prenatal smoking and caffeine consumption during pregnancy are associated with an increased risk of adverse maternal and perinatal outcomes." | 7.72 | Consequences of smoking and caffeine consumption during pregnancy in women with type 1 diabetes. ( Buncher, CR; Kalkwarf, H; Khoury, JC; Khoury, PR; McElvy, S; Miodovnik, M; Sibai, B, 2004) |
| "Signals of early pregnancy included an aversion to coffee in addition to nausea and vomiting, which resulted in decreased caffeine consumption." | 7.72 | Changes in caffeine consumption as a signal of pregnancy. ( Lawson, CC; LeMasters, GK; Wilson, KA, 2004) |
| "Excessive maternal caffeine exposure during pregnancy had cataractogenic effects on developing crystalline lenses in newborn rat eyes, both macroscopically and histopathologically." | 7.72 | Excessive maternal caffeine exposure during pregnancy is cataractogenic for neonatal crystalline lenses in rats: a biomicroscopic and histopathologic study. ( Alasehirli, B; Cengiz, B; Evereklioglu, C; Güldür, E; Pirbudak, L; Sari, I, 2004) |
| "Excessive ingestion of caffeine can induce hypokalemia, which affects the neuromuscular system and can lead to paralysis." | 7.71 | Caffeine-induced hypokalemic paralysis in pregnancy. ( Appel, CC; Myles, TD, 2001) |
| "Epidemiologic studies have been unable to conclusively evaluate whether caffeine intake during pregnancy is associated with reduced birth weight and/or fetal growth restriction." | 7.71 | Effect of caffeine exposure during pregnancy on birth weight and gestational age. ( Clausson, B; Cnattingius, S; Ekbom, A; Granath, F; Lundgren, S; Nordmark, A; Signorello, LB, 2002) |
| "Previous studies of maternal caffeine use and pregnancy outcome have relied on self-reported use." | 7.70 | Serum caffeine and paraxanthine as markers for reported caffeine intake in pregnancy. ( Clemens, JD; Dersimonian, R; Klebanoff, MA; Levine, RJ; Wilkins, DG, 1998) |
| "To examine the association between maternal caffeine consumption during pregnancy and the risk of sudden infant death syndrome (SIDS)." | 7.70 | Heavy caffeine intake in pregnancy and sudden infant death syndrome. New Zealand Cot Death Study Group. ( Ford, RP; Mitchell, EA; Schluter, PJ; Scragg, R; Stewart, AW; Taylor, BJ, 1998) |
| "The authors conducted a matched case-control study to investigate the effects of caffeine intake during pregnancy on birth weight." | 7.70 | Caffeine intake and low birth weight: a population-based case-control study. ( Carvalhal, JB; Huttly, S; Santos, IS; Victora, CG, 1998) |
| "Motherisk's recent meta-analysis suggests that the risks for miscarriage and fetal growth retardation increase only with daily doses of caffeine above 150 mg/d, equivalent to six typical cups of coffee a day." | 7.70 | Caffeine during pregnancy? In moderation. ( Koren, G, 2000) |
| "To examine the association of plasma caffeine concentrations during pregnancy with fetal growth and to compare this with relations with reported caffeine intake." | 7.69 | Relation of caffeine intake and blood caffeine concentrations during pregnancy to fetal growth: prospective population based study. ( Anderson, HR; Bland, JM; Carey, IM; Cook, DG; Feyerabend, C; Jarvis, MJ; Peacock, JL, 1996) |
| "The aim of this study was to examine the effect of caffeine consumption during pregnancy on birth weight and its possible interaction with smoking." | 7.69 | Effect of caffeine intake during pregnancy on birth weight. ( Adanja, BJ; Marinković, JM; Petrović, RR; Sipetić, SB; Vlajinac, HD, 1997) |
| "To assess the prevalence of smoking and of caffeine and alcohol intake during pregnancy in a northern population and to determine the relation of these factors to birth weight, length and head circumference." | 7.68 | Smoking and caffeine and alcohol intake during pregnancy in a northern population: effect on fetal growth. ( Froese, GJ; Godel, JC; Hodges, PE; Joffres, MR; Johnson, KE; Pabst, HF, 1992) |
| "Mice were administered caffeine (500 mg/liter of drinking water) from d 1 until d 18 of pregnancy." | 7.68 | Caffeine administered during pregnancy augments subsequent lactation in mice. ( Sheffield, LG, 1991) |
| "In a previous paper, I have proposed that the deficiency of an endogenous caffeine-like substance is the underlying pathogenic mechanism in schizophrenia (1)." | 7.68 | Exploring the role of an endogenous caffeine-like substance in the pathogenesis of schizophrenia. ( Missak, SS, 1991) |
| "Taken together with studies reporting similar findings, these results suggest that heavy caffeine consumption increases the risk for fetal growth retardation." | 7.68 | Caffeine consumption during pregnancy and fetal growth. ( Eskenazi, B; Fenster, L; Swan, SH; Windham, GC, 1991) |
| " We analyzed data on 607 cases and 1,284 controls to evaluate the potential association between caffeine consumption during the first trimester of pregnancy and spontaneous abortion." | 7.68 | Caffeine consumption during pregnancy and spontaneous abortion. ( Eskenazi, B; Fenster, L; Swan, SH; Windham, GC, 1991) |
| "In this manuscript it is demonstrated that caffeine when administered to the rat (30 mg/kg per day) during pregnancy affected certain aspects of normal sexual differentiation of the fetal gonads." | 7.68 | Influence of caffeine administered during pregnancy on the early differentiation of fetal rat ovaries and testes. ( Magre, S; Pollard, I; Williamson, S, 1990) |
| "Whether caffeine intake during pregnancy is related to intrauterine growth retardation, low birth weight, and preterm birth remains unclear." | 7.68 | Relation of caffeine intake during pregnancy to intrauterine growth retardation and preterm birth. ( Beaulac-Baillargeon, L; Fortier, I; Marcoux, S, 1993) |
| "The aim of this study was to investigate the effect of alcohol and caffeine consumption on birth weight and the possible interaction of these substances with smoking." | 7.68 | Effects of birth weight of alcohol and caffeine consumption during pregnancy. ( Dehaene, P; Kaminski, M; Larroque, B; Lelong, N; Subtil, D, 1993) |
| "To investigate the effects of smoking, alcohol, and caffeine consumption and socio-economic factors and psychosocial stress on birth weight." | 7.67 | Effects on birth weight of smoking, alcohol, caffeine, socioeconomic factors, and psychosocial stress. ( Anderson, HR; Bland, JM; Brooke, OG; Peacock, JL; Stewart, CM, 1989) |
| "Alcohol and caffeine consumption during pregnancy are risk factors for fetal outcome." | 7.67 | Neural tube defects in early rat embryos following maternal treatment with ethanol and caffeine. ( Persaud, TV; Ross, CP, 1989) |
| " Comparison of the groups using quantitative measures of apnea, bradycardia, and periodic breathing obtained from pneumogram analysis and the incidence of monitor alarms on bedside nursing records showed no significant differences." | 7.67 | Transplacentally acquired caffeine and the occurrence of apnea, bradycardia, and periodic breathing in preterm infants: preliminary communication. ( Braun, RJ; Evans, MA; Kelly, DH; McCulloch, KM; Simms, PE, 1989) |
| "Various levels of maternal caffeine ingestion during pregnancy were investigated to determine whether caffeine will affect the mineral contents of the growing bones of fetal rats." | 7.67 | The effects of maternal caffeine intake during pregnancy on mineral contents of fetal rat bone. ( Grant, S; Nakamoto, T; Yazdani, M, 1989) |
| "The mandibles and long bones of newborn rats were analyzed for the effects of maternal caffeine consumption and protein-energy malnutrition." | 7.67 | Protein-energy malnutrition in rats during pregnancy modifies the effects of caffeine on fetal bones. ( Nakamoto, T; Shaye, R, 1986) |
| "Caffeine, when administered in moderate (30 mg/kg X d) or high (60 mg/kg X d) doses during pregnancy, was shown to cause significant fetal growth retardation of both sexes." | 7.67 | Effects of caffeine administered during pregnancy on fetal development and subsequent function in the adult rat: prolonged effects on a second generation. ( Jabbour, H; Mehrabani, PA; Pollard, I, 1987) |
| "To evaluate the relationship of antecedent maternal smoking and caffeine consumption habits on the occurrence of apnea in their offspring, rates for central and obstructive apnea were analyzed in a cohort of mother-infant pairs." | 7.67 | Effects of maternal smoking and caffeine habits on infantile apnea: a retrospective study. ( Bendell, D; Duke, JC; Mattice, CD; McCaffree, MA; Orr, WC; Toubas, PL, 1986) |
| "In a prospective cohort study, 3135 pregnant women were followed to evaluate the association of caffeine consumption during pregnancy with late first- and second-trimester spontaneous abortion." | 7.67 | Caffeine consumption during pregnancy and association with late spontaneous abortion. ( Bracken, MB; Srisuphan, W, 1986) |
| "After literature reports linking fibrocystic breast disease (FBD) to methylxanthine ingestion, a pilot study was undertaken to investigate the possible contribution of theophylline to this effect." | 7.67 | Theophylline and fibrocystic breast disease. ( Bullough, B; Hindi-Alexander, MC; London, WM; Middleton, E; Montes, N; Rosner, DH; Zielezny, MA, 1985) |
| "We studied the effects of caffeine ingestion during pregnancy." | 7.67 | Effects of caffeine ingestion during pregnancy. ( Furuhashi, N; Hiruta, M; Sato, S; Suzuki, M; Takahashi, T; Tanaka, M, 1985) |
| "We studied whether protein-energy malnutrition changed brain susceptibility to a small dose of caffeine in newborn rats." | 7.67 | Protein-energy malnutrition during pregnancy alters caffeine's effect on brain tissue of neonate rats. ( Mori, M; Nakamoto, T; Wilber, JF, 1984) |
| "The toxic interaction of caffeine and phenytoin during pregnancy was investigated in mice of the ICR strain on E10 of gestation." | 7.67 | The toxicology of chemical interactions during pregnancy in the mouse: caffeine and phenytoin. ( Kwasigroch, TE; Poche, PD; Skalko, RG, 1984) |
| "Use of alcohol, caffeine, and nicotine during pregnancy can have serious consequences for the fetus, such as low birth weight, congenital anomalies, or even death." | 7.66 | Alcohol, caffeine, and nicotine as factors in pregnancy. ( Lodge, JR; Weathersbee, PS, 1979) |
| "The newborn's potential for xanthine toxic reactions from placental transfer of theophylline or caffeine conversion from theophylline was studied in 12 newborns of asthmatic mothers." | 7.66 | Placental theophylline transfer in pregnant asthmatics. ( Labovitz, E; Spector, S, 1982) |
| "Caffeine or NaCl 0." | 6.90 | Caffeine administered to pregnant sows improves piglet vitality, gas exchange and body weight gain. ( Ballesteros-Rodea, G; Bonilla-Jaime, H; González-Hernández, M; González-Lozano, M; Orozco-Gregorio, H; Roldán-Santiago, P; Sánchez-Salcedo, JA, 2019) |
| "To evaluate the efficacy of occipital nerve block compared with standard care , defined as acetaminophen with caffeine, for treatment of acute headache in pregnancy." | 5.69 | Occipital Nerve Block Compared With Acetaminophen and Caffeine for Headache Treatment in Pregnancy: A Randomized Controlled Trial. ( Blanchard, CT; Bushman, ET; Casey, BM; Cozzi, GD; Davis, AM; Digre, KB; Harper, L; Jones, B; Robbins, LS; Sinkey, RG; Szychowski, JM; Tita, AT, 2023) |
| "Caffeine exposure was associated to SGA (OR = 1." | 5.51 | Caffeine exposure during pregnancy, small for gestational age birth and neonatal outcome - results from the Norwegian Mother and Child Cohort Study. ( Bellocco, R; Brantsæter, AL; Elfvin, A; Jacobsson, B; Meltzer, HM; Modzelewska, D; Sengpiel, V, 2019) |
| "To examine 5-year outcomes in children enrolled in a pilot randomized controlled trial of a high loading dose of caffeine after preterm birth." | 5.51 | Five-year outcomes of premature infants randomized to high or standard loading dose caffeine. ( Cyr, PEP; Inder, TE; Lean, RE; McPherson, C; Rogers, CE; Smyser, CD, 2022) |
| "Febrile seizures (FS) is one of the most common convulsive disorders in infants and young children that only occurs during the first years of life in humans, when the cerebellum is still developing." | 5.48 | Cerebellar oxidative stress and fine motor impairment in adolescent rats exposed to hyperthermia-induced seizures is prevented by maternal caffeine intake during gestation and lactation. ( Crespo, M; León-Navarro, DA; Martín, M, 2018) |
| " Higher blood levels of caffeine within the range considered therapeutic and safe for human infants correlated with increased neuroapoptosis." | 5.48 | Caffeine Augments Anesthesia Neurotoxicity in the Fetal Macaque Brain. ( Brambrink, AM; Dissen, GA; Ikonomidou, C; Johnson, SA; Manzella, FM; Martin, LD; Masuoka, KL; Noguchi, KK; Olney, JW; Schenning, KJ; Williams, SL, 2018) |
| "Caffeine consumption has been widely used as a central nervous system stimulant." | 5.48 | Caffeine consumption during early pregnancy impairs oviductal embryo transport, embryonic development and uterine receptivity in mice. ( Chen, Q; Duan, E; Hwang, SJ; Kim, BH; Liu, S; Qian, J; Qu, Y; Shi, J; Ward, SM; Zhang, L; Zhang, X; Zhang, Y; Zhou, T, 2018) |
| "Caffeine is an alkaloid that is widely consumed due to its presence in drugs, coffee, tea, and chocolate." | 5.43 | Inhibition of the osteogenic differentiation of mesenchymal stem cells derived from the offspring of rats treated with caffeine during pregnancy and lactation. ( Boeloni, JN; Ferreira, Ada F; Goes, AM; Gomes, DA; Ocarino, Nde M; Reis, AM; Serakides, R, 2016) |
| "Furthermore, caffeine treatment during pregnancy and lactation causes long-term behavioral changes in the mice offspring that manifest later in life." | 5.43 | Behavioral profile assessment in offspring of Swiss mice treated during pregnancy and lactation with caffeine. ( Côrtes, Wda S; da Conceição, RR; da Rocha, FF; da Silva-Almeida, C; da Silveira, AL; de Azevedo Cruz Seara, F; Laureano-Melo, R; Marinho, BG; Reis, LC, 2016) |
| " This association demonstrated a dose-response relationship: OR=1." | 5.42 | Maternal caffeine intake during pregnancy and risk of obesity in offspring: a prospective cohort study. ( Ferber, JR; Li, DK; Odouli, R, 2015) |
| "Severe NAFLD appeared with higher Kleiner scores." | 5.40 | Intrauterine metabolic programming alteration increased susceptibility to non-alcoholic adult fatty liver disease in prenatal caffeine-exposed rat offspring. ( Chen, L; Huang, H; Liu, Y; Liu, Z; Ping, J; Shen, L; Wang, H; Wang, L; Wu, Y; Zhang, L, 2014) |
| "Caffeine intake was consistently associated with decreased BW and increased odds of SGA." | 5.39 | Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results from a large prospective observational cohort study. ( Alexander, J; Bacelis, J; Brantsaeter, AL; Elind, E; Grove, J; Haugen, M; Jacobsson, B; Meltzer, HM; Myhre, R; Nilsson, S; Sengpiel, V, 2013) |
| "Caffeine also has a potentially negative influence on bones." | 5.37 | The influence of caffeine on the biomechanical properties of bone tissue during pregnancy in a population of rats. ( Chadaj-Polberg, E; Olchowik, G; Polberg, M; Tomaszewska, M; Tomaszewski, M, 2011) |
| "There were 84 cases of undescended testes at birth persisting to at least age 2 years among 7,574 liveborn sons whose mothers were interviewed in early pregnancy." | 5.35 | Maternal smoking, alcohol consumption, and caffeine consumption during pregnancy in relation to a son's risk of persistent cryptorchidism: a prospective study in the Child Health and Development Studies cohort, 1959-1967. ( Christianson, RE; Cohen, RD; Cohn, BA; Mongraw-Chaffin, ML, 2008) |
| "Caffeine is a widely used psychostimulant freely crossing the placental barrier." | 5.35 | Maternal caffeine ingestion during gestation and lactation influences respiratory adaptation to acute alveolar hypoxia in newborn rats and adenosine A2A and GABA A receptor mRNA transcription. ( Guénin, S; Larnicol, N; Perrin, Y; Picard, N, 2008) |
| " However, postimplantation embryo development assessed on Day 12 of gestation revealed that caffeine exposure of 15 and 30 mg kg(-1) significantly reduced, at both dosage levels, somite number and the extent of neural tube closure." | 5.30 | Maternal caffeine consumption during pregnancy does not affect preimplantation development but delays early postimplantation growth in rat embryos. ( Jacombs, A; Loupis, A; Pollard, I; Ryan, J, 1999) |
| " Prenatal caffeine at the dosage we have used in combination with malnutrition may produce lasting metabolic alterations in the nervous system related to the emergence of suckling behavior and general motor activity." | 5.29 | Combined effects of caffeine and malnutrition during pregnancy on suckling behavior in newborn rats. ( Joseph, F; Nakamoto, T; Narayanan, CH; Saito, T; Yoshino, S, 1994) |
| "The pharmacokinetic parameters of caffeine were measured in 9 pregnant women and 4 women 4 days post partum." | 5.27 | Pharmacokinetics of caffeine during and after pregnancy. ( Berland, M; Brazier, JL; Faucon, G; Khenfer, D; Ritter, J, 1983) |
| " An increase of the half-life of elimination of caffeine has been reported during the final weeks of pregnancy." | 5.26 | The effect of pregnancy on the pharmacokinetics of caffeine. ( Knutti, R; Rothweiler, H; Schlatter, C, 1982) |
| "Caffeine elimination was studied in 15 women at 38 to 40 weeks' gestation." | 5.26 | Delayed elimination of caffeine by women in the last 2 weeks of pregnancy. ( Parsons, WD; Pelletier, JG, 1982) |
| "Caffeine has a multitude of pharmacologic actions and its effects must be determined on the fetus and newborn in the immediate future for suggestive evidence links caffeine with such fetal and newborn pathology as pre- and postmaturity and intrauterine growth retardation." | 5.26 | Caffeine ingestion during pregnancy: in utero exposure and possible effects. ( Soyka, LF, 1981) |
| "This study sought to assess the pharmacokinetic (PK) changes of caffeine and its CYP1A2 metabolites across the 3 trimesters of pregnancy." | 5.22 | Pregnancy-induced changes in the pharmacokinetics of caffeine and its metabolites. ( Campbell, SC; Clark, EA; Schoen, K; Sherwin, CM; Spigarelli, MG; Stockmann, C; Tak, C; Varner, MW; Yu, T, 2016) |
| "To evaluate the effectiveness and safety of different doses of caffeine in treatment of primary apnea in preterm infants." | 5.22 | [Clinical effectiveness of different doses of caffeine for primary apnea in preterm infants]. ( Liu, G; Tian, X; Zhao, Y, 2016) |
| " Among them, magnesium sulfate, given antenatally to pregnant women with imminent preterm birth before 30 to 34 weeks of gestation, as well as caffeine administered to preterm infants after birth, exhibited neuroprotective effects for human preterm brain." | 5.22 | Pharmacological Neuroprotection of the Preterm Brain: Current Evidence and Perspectives. ( Siahanidou, T; Spiliopoulou, C, 2022) |
| " Findings with alcohol and caffeine exposures and conduct disorder and oppositional-defiant disorder need more research, using more genetically sensitive designs." | 5.22 | Prenatal smoking, alcohol and caffeine exposure and offspring externalizing disorders: a systematic review and meta-analysis. ( Haan, E; Munafò, MR; Sallis, HM; Schellhas, L; Taylor, G; Westmoreland, KE; Zuccolo, L, 2022) |
| " A large percentage of women continue to consume this drink during pregnancy, while a significant proportion of them exceed the permissible daily dose of caffeine (≤ 200 mg)." | 5.22 | Coffee consumption during pregnancy - what the gynecologist should know? Review of the literature and clinical studies. ( Surma, S; Witek, A, 2022) |
| "The potential effect of caffeine exposure during pregnancy on gestational hypertension (GH)/preeclampsia has attracted attention but remains unclear." | 5.22 | The association between caffeine exposure during pregnancy and risk of gestational hypertension/preeclampsia: A meta-analysis and systematical review. ( Chen, B; He, Y; Hong, J; Jiang, K; Ni, S; Shen, J; Shi, Y; Si, Y; Zhang, M, 2022) |
| "There was no association between caffeine consumption and pregnancy or live birth rate of IVF/ICSI." | 5.22 | The association between caffeine and alcohol consumption and IVF/ICSI outcomes: A systematic review and dose-response meta-analysis. ( Li, N; Li, Y; Rao, W; Yao, Q, 2022) |
| " In this study, a meta-analysis was first performed to suggest that paternal exposure to nicotine, ethanol, or caffeine is a high-risk factor for adverse pregnancy outcomes." | 5.22 | Paternal Nicotine/Ethanol/Caffeine Mixed Exposure Induces Offspring Rat Dysplasia and Its Potential "GC-IGF1" Programming Mechanism. ( Chen, L; Chen, M; Liu, Y; Qu, H; Wang, H; Xu, D; Zhang, C; Zhou, S; Zhu, J, 2022) |
| "Recent work showing that caffeine impairs glucose tolerance may be of particular concern in pregnancy because of a possible negative effect on fetal outcome." | 5.14 | Acute caffeine ingestion and glucose tolerance in women with or without gestational diabetes mellitus. ( Graham, TE; Robinson, LE; Smith, GN; Spafford, C, 2009) |
| "To estimate the effect of reducing caffeine intake during pregnancy on birth weight and length of gestation." | 5.12 | Effect of reducing caffeine intake on birth weight and length of gestation: randomised controlled trial. ( Bech, BH; Henriksen, TB; Obel, C; Olsen, J, 2007) |
| "The physiologic effects and common use of caffeine during pregnancy call for examination of maternal caffeine consumption and risk of birth defects." | 5.12 | Maternal caffeine consumption and risk of cardiovascular malformations. ( Bell, EM; Browne, ML; Correa, A; Druschel, CM; Gensburg, LJ; Lin, AE; Mitchell, AA; Romitti, PA, 2007) |
| "Database searches using terms linking caffeine and caffeinated beverages to pregnancy outcomes identified 1261 English language peer-reviewed articles." | 5.12 | Maternal caffeine consumption and pregnancy outcomes: a narrative review with implications for advice to mothers and mothers-to-be. ( James, JE, 2021) |
| "Forty postpartum patients with postdural puncture headache (PDPH) were randomly assigned to receive oral caffeine (300 mg) or a placebo." | 5.06 | Effects of oral caffeine on postdural puncture headache. A double-blind, placebo-controlled trial. ( Camann, WR; Lambert, DH; Murray, RS; Mushlin, PS, 1990) |
| "In a double-blind, randomized controlled trial among 500 post-partum patients experiencing moderate to severe pain, a single oral dose of an aspirin/caffeine combination (800 mg aspirin, 65 mg caffeine) provided significantly more pain relief at 2 hours than did a higher dose of an acetaminophen/aspirin combination (648 mg acetaminophen, 648 mg aspirin) and a higher dose of acetaminophen alone (1000 mg acetaminophen)." | 5.05 | A double-blind randomized study of an aspirin/caffeine combination versus acetaminophen/aspirin combination versus acetaminophen versus placebo in patients with moderate to severe post-partum pain. ( Rubin, A; Winter, L, 1984) |
| "Epidemiological studies have revealed that caffeine consumption during pregnancy is associated with adverse gestational outcomes, yet the underlying mechanisms remain obscure." | 5.05 | Impacts of Caffeine during Pregnancy. ( Chen, Q; Duan, E; Qian, J; Ward, SM; Zhang, Y, 2020) |
| " EBPCS is defined as the management of the VPIs during the perinatal period which would include antenatal counseling with team briefing and share decision making, treat the chorioamnionitis, antenatal MgS04, antenatal steroid, delayed cord clamping/milking, neonatal resuscitation team preparation, prevention of hypothermia, immediate respiratory support with continuous positive airway pressure at delivery room, less invasive surfactant administration, early surfactant with budesonide therapy, support of cardiovascular system, early initiate of probiotics administration, early caffeine, early parenteral and enteral nutrition, promptly initiating antibiotics." | 5.05 | Evidence base multi-discipline critical strategies toward better tomorrow for very preterm infants. ( Chen, YT; Chiu, HY; Chu, SM; Lin, HC; Lin, HY; Tsai, ML, 2020) |
| " Intake of supplemental folic acid, particularly at doses higher than those recommended for the prevention of neural tube defects, has been consistently related to lower frequency of infertility, lower risk of pregnancy loss, and greater success in infertility treatment." | 4.98 | Diet and fertility: a review. ( Chavarro, JE; Gaskins, AJ, 2018) |
| "Caffeine reduces the risk of bronchopulmonary dysplasia (BPD)." | 4.98 | Optimizing Caffeine Use and Risk of Bronchopulmonary Dysplasia in Preterm Infants: A Systematic Review, Meta-analysis, and Application of Grading of Recommendations Assessment, Development, and Evaluation Methodology. ( Pakvasa, MA; Patel, RM; Saroha, V, 2018) |
| "To assess the association between maternal caffeine intake and risk of pregnancy loss using a systematic review and meta-analysis." | 4.93 | Maternal caffeine intake during pregnancy and risk of pregnancy loss: a categorical and dose-response meta-analysis of prospective studies. ( Chen, LW; Chong, MF; Neelakantan, N; Pan, A; van Dam, RM; Wu, Y, 2016) |
| " Reducing caffeinated coffee consumption by 180 mg of caffeine (the equivalent of 2 cups) per day after 16 weeks' gestation doesn't affect birth weight." | 4.93 | Clinical Inquiry: Does caffeine intake during pregnancy affect birth weight? ( Adams, T; Kelsberg, G; Safranek, S, 2016) |
| "This aim of this study was to conduct a systematic literature review on the association between maternal caffeine intake during pregnancy and attention deficit hyperactivity disorder (ADHD) in childhood." | 4.91 | [Caffeine consumption during pregnancy and attention deficit hyperactivity disorder (ADHD): a systematic literature review]. ( Anselmi, L; Santos, IS; Schmidt, V; Silva, Bdel P, 2015) |
| "Previous reports of the relationship between pregnancy loss and caffeine/coffee consumption have been inconsistent." | 4.91 | A meta-analysis of risk of pregnancy loss and caffeine and coffee consumption during pregnancy. ( Li, J; Song, JM; Tang, YL; Xin, CM; Zhang, J; Zhao, H, 2015) |
| "Maternal caffeine consumption during pregnancy may have adverse effects on fetal, neonatal and maternal outcomes." | 4.91 | Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcomes. ( Jaafar, SH; Jahanfar, S, 2015) |
| "Caffeine is commonly consumed during pregnancy, crosses the placenta, with fetal serum concentrations similar to the mother's, but studies of birth outcome show conflicting findings." | 4.90 | Caffeine intake during pregnancy and adverse birth outcomes: a systematic review and dose-response meta-analysis. ( Cade, JE; Garrard, L; Greenwood, DC; Keogh, G; King, LG; Thatcher, NJ; Ye, J, 2014) |
| "Considerable controversy exists regarding the relation between maternal caffeine intake during pregnancy and risk of low birth weight (birth weight <2,500 g)." | 4.90 | Maternal caffeine intake during pregnancy is associated with risk of low birth weight: a systematic review and dose-response meta-analysis. ( Chen, LW; Chong, MF; Neelakantan, N; Pan, A; van Dam, RM; Wu, Y, 2014) |
| " The earlier review included 20 studies (7238 participants) in valid comparisons, but because we used different outcomes for some headache studies, the number of participants in the analyses of the effects of caffeine is now 4262 when previously it was 5243." | 4.90 | Caffeine as an analgesic adjuvant for acute pain in adults. ( Derry, CJ; Derry, S; Moore, RA, 2014) |
| "Compounds other than macronutrients have been shown to influence blood glucose concentrations and insulin sensitivity in people with diabetes, with caffeine being one such substance." | 4.89 | Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus. ( White, H; Whitehead, N, 2013) |
| "Maternal caffeine consumption during pregnancy may have adverse effects on fetal, neonatal and maternal outcomes." | 4.89 | Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcome. ( Jaafar, SH; Jahanfar, S, 2013) |
| " Most studies used paracetamol or ibuprofen, with 100 mg to 130 mg caffeine, and the most common pain conditions studied were postoperative dental pain, postpartum pain, and headache." | 4.88 | Caffeine as an analgesic adjuvant for acute pain in adults. ( Derry, CJ; Derry, S; Moore, RA, 2012) |
| "A risk analysis of in utero caffeine exposure is presented utilizing epidemiological studies and animal studies dealing with congenital malformation, pregnancy loss, and weight reduction." | 4.87 | Evaluation of the reproductive and developmental risks of caffeine. ( Brent, RL; Christian, MS; Diener, RM, 2011) |
| "We performed a meta-analysis examining the association between caffeine consumption during pregnancy and risk of preterm birth." | 4.86 | Caffeine consumption during pregnancy and risk of preterm birth: a meta-analysis. ( Bhattacharya, S; Lin, SW; Maslova, E; Michels, KB, 2010) |
| "Maternal caffeine consumption during pregnancy may have adverse effects on fetal, neonatal and maternal outcomes." | 4.85 | Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcome. ( Jahanfar, S; Sharifah, H, 2009) |
| "Maternal use of "social drugs" such as caffeine, ethanol and tobacco in pregnancy is on increase- -worldwide." | 4.85 | Peripartum implications of caffeine intake in pregnancy: is there cause for concern? ( Kuczkowski, KM, 2009) |
| "This article reports on a systematic review of studies on caffeine intake during pregnancy and prevalence of low birth weight and prematurity, focusing on methods to quantify intake and control for confounding." | 4.84 | [Caffeine consumption during pregnancy and prevalence of low birth weight and prematurity: a systematic review]. ( Barreiros, NS; Kac, G; Pacheco, AH; Santos, IS, 2007) |
| "The purpose of this review was to examine the literature assessing the relationship between prenatal exposure to nicotine, alcohol, caffeine, and psychosocial stress during pregnancy to the risk of developing behavioral problems related to attention deficit hyperactivity disorder (ADHD) in childhood." | 4.82 | Maternal lifestyle factors in pregnancy risk of attention deficit hyperactivity disorder and associated behaviors: review of the current evidence. ( Dalsgaard, S; Henriksen, TB; Jarvelin, MR; Kotimaa, A; Linnet, KM; Moilanen, I; Obel, C; Olsen, J; Rodriguez, A; Thomsen, PH; Wisborg, K, 2003) |
| "Since the 1980s, numerous studies have investigated whether caffeine intake during pregnancy affects the risk of spontaneous abortion." | 4.82 | Maternal caffeine consumption and spontaneous abortion: a review of the epidemiologic evidence. ( McLaughlin, JK; Signorello, LB, 2004) |
| " Food and Drug Administration of 1981, a review of human epidemiological studies finds no adverse effect of caffeine on pregnancy outcome." | 4.77 | Caffeine consumption and the risk of reproductive hazards. ( Leviton, A, 1988) |
| "Caffeine consumption is common during pregnancy, but published associations with birth defects are mixed." | 4.31 | Maternal dietary caffeine consumption and risk of birth defects in the National Birth Defects Prevention Study, 1997-2011. ( Browne, ML; Conway, KM; Fisher, SC; Howley, MM; Olshan, AF; Reeder, MR; Reefhuis, J; Romitti, PA; Williford, EM, 2023) |
| "Despite the widespread use of caffeine including consumption during pregnancy, the effect of prenatal caffeine exposure on child brain development and behavior is unclear." | 4.12 | Prenatal caffeine exposure: association with neurodevelopmental outcomes in 9- to 11-year-old children. ( Manza, P; Volkow, ND; Zhang, R, 2022) |
| "We examined preconception and pregnancy caffeine exposure with DNAm alterations in neonate cord blood (n = 378)." | 4.12 | Maternal caffeine intake and DNA methylation in newborn cord blood. ( Guan, W; Mumford, SL; Polinski, KJ; Purdue-Smithe, A; Robinson, SL; Schisterman, EF; Schliep, KC; Silver, RM; Yeung, EH; Zhao, SK, 2022) |
| "Our previous study reported that prenatal caffeine exposure (PCE) could induce chondrodysplasia and increase the susceptibility to osteoarthritis in offspring rats." | 4.12 | Intrauterine programming of cartilaginous 11β-HSD2 induced by corticosterone and caffeine mediated susceptibility to adult osteoarthritis. ( Chen, L; Gao, H; He, H; Li, B; Magdaloud, J; Shi, H; Wang, H; Wu, Z, 2022) |
| " Among the external factors, chemical compounds stand out, which include caffeine, since its consumption is common among women, including during pregnancy." | 4.12 | Behavioral, genetic and biochemical changes in the brain of the offspring of female mice treated with caffeine during pregnancy and lactation. ( Boeck, CR; Borges Correa, MEA; Budni, J; Damiani, AP; de Andrade, VM; de Bem Silveira, G; de Marcos, PS; Effting, PS; Franca, IB; Magenis, ML; Medeiros, EB; Muller, AP; Silveira, PCL, 2022) |
| " Models accounted for women's age, BMI, employment, marital status, income, education, race, parity, prior losses, exercise and time-varying nausea/vomiting, caffeine, alcohol and smoking." | 4.12 | Prospectively assessed perceived stress associated with early pregnancy losses among women with history of pregnancy loss. ( Hinkle, SN; Kim, K; Mumford, SL; Plowden, TC; Purdue-Smithe, A; Schisterman, EF; Schliep, KC; Silver, RM; Sjaarda, LA; Stanford, JB, 2022) |
| "Caffeine consumption during pregnancy has effect on newborn anthropometry therefore the amount of maternal caffeine consumption is important." | 4.12 | The caffeine consumption among Turkish pregnant women. ( Apay, SE; Cil, MA; Gur, EY, 2022) |
| "Greater caffeine consumption in pregnancy is associated with reduced birth size, but potential associations with childhood growth are unclear." | 4.12 | Association of Maternal Caffeine Consumption During Pregnancy With Child Growth. ( Gilman, SE; Gleason, JL; Grantz, KL; Grobman, WA; Hinkle, SN; Hunt, KJ; Kannan, K; Mitro, SD; Nageotte, M; Newman, RB; Robinson, M; Skupski, DW; Sundaram, R; Zhang, C, 2022) |
| "High-maternal caffeine intake during pregnancy may be harmful for perinatal outcomes and future child health, but the level of fetal cumulative exposure has been difficult to measure thus far." | 4.02 | Caffeine content in newborn hair correlates with maternal dietary intake. ( Auriola, S; Backman, K; Hantunen, S; Heinonen, S; Keski-Nisula, L; Lehtonen, A; Lehtonen, M; Pasanen, M; Pekkanen, J; Tuomainen, TP; Uusitalo, L; Voutilainen, R, 2021) |
| "Low to moderate caffeine consumption during pregnancy was not associated with any persistent adverse effects concerning the child's neurodevelopment up to 8 years of age." | 4.02 | Maternal caffeine intake during pregnancy and child neurodevelopment up to eight years of age-Results from the Norwegian Mother, Father and Child Cohort Study. ( Berglundh, S; Brandlistuen, R; Brantsæter, AL; Jacobsson, B; Sengpiel, V; Solé-Navais, P; Vollrath, M, 2021) |
| "To examine the association between maternal caffeine intake during pregnancy and the development of food allergy in young Japanese children up to 3 years of age." | 4.02 | Maternal caffeine intake during pregnancy and risk of food allergy in young Japanese children. ( Arakawa, M; Miyake, Y; Okubo, H; Sasaki, S; Tanaka, K, 2021) |
| "Higher caffeine consumption during pregnancy has been associated with lower birth weight." | 4.02 | Association Between Maternal Caffeine Consumption and Metabolism and Neonatal Anthropometry: A Secondary Analysis of the NICHD Fetal Growth Studies-Singletons. ( Amyx, M; Bever, AM; Buck Louis, GM; Gerlanc, N; Gleason, JL; Grantz, KL; Hinkle, SN; Kannan, K; Robinson, M; Smarr, MM; Sundaram, R; Tekola-Ayele, F; Vafai, Y, 2021) |
| "To determine whether caffeinated-beverage intake and plasma caffeine and paraxanthine are associated with cardiometabolic complications in pregnancy (ie, gestational diabetes [GDM], preeclampsia, and gestational hypertension [GH])." | 4.02 | Assessment of Caffeine Consumption and Maternal Cardiometabolic Pregnancy Complications. ( Gleason, JL; Grantz, KL; Grewal, J; Hinkle, SN; Mumford, SL; Sundaram, R; Yisahak, SF; Zhang, C; Zhao, SK, 2021) |
| "Our previous studies confirmed that prenatal caffeine exposure (PCE) could induce susceptibility to osteoarthritis in adult offspring rats due to poor chondrocyte differentiation, but its mechanism remains to be further investigated." | 3.96 | Subchondral bone dysplasia mediates susceptibility to osteoarthritis in female adult offspring rats induced by prenatal caffeine exposure. ( Chen, L; Magdalou, J; Tan, Y; Wang, H; Wen, Y; Xiao, H; Xie, X, 2020) |
| "Maternal caffeine intake during pregnancy is associated with an increased risk of childhood obesity." | 3.96 | Associations of maternal caffeine intake during pregnancy with abdominal and liver fat deposition in childhood. ( Gaillard, R; Hulst, ME; Jaddoe, VW; Oei, EH; Voerman, E, 2020) |
| "Our results showed that heavy coffee drinking was independently associated with a higher risk of bleeding in early pregnancy among pregnant Korean women, suggesting that caffeine intake before conception and during pregnancy should be reduced." | 3.96 | Maternal coffee intake and the risk of bleeding in early pregnancy: a cross-sectional analysis. ( Choi, H; Koo, S; Park, HY, 2020) |
| "The use of excessive caffeine and consumption of alcohol, cigarette, and khat during pregnancy can result in adverse health effects on the fetus." | 3.96 | Caffeine, alcohol, khat, and tobacco use during pregnancy in Butajira, South Central Ethiopia. ( Alamneh, AA; Endris, BS; Gebreyesus, SH, 2020) |
| " Women noted their mother's reported use of diethylstilbestrol (DES), vitamins, tobacco, alcohol, and caffeine during pregnancy, and their mother's occupation during pregnancy." | 3.96 | Recalled maternal lifestyle behaviors associated with anti-müllerian hormone of adult female offspring. ( DeCherney, AH; Eubanks, AA; Hill, MJ; Kim, K; Mumford, SL; Nobles, CJ; Perkins, NJ; Schisterman, EF; Silver, RM; Sjaarda, LA; Ye, A; Zolton, JR, 2020) |
| "In the pregnancy period, it is recommended to limit the consumption of caffeine." | 3.96 | The dosage-dependent prenatal caffeine exposure adversely affects levels of integrin αVβ3 and MMP-9 in a rat model of embryo implantation. ( Tekmen, I; Yilmaz, F, 2020) |
| " Rats were divided into three groups on the first day of pregnancy: (1) control: tap water, (2) caffeine: 0." | 3.96 | Effects of gestational and breastfeeding caffeine exposure in adenosine A1 agonist-induced antinociception of infant rats. ( Adachi, LNS; Assumpção, JAF; Battastini, AMO; Caumo, W; Cioato, SG; de Oliveira, C; de Souza, A; Medeiros, LF; Rozisky, JR; Scarabelot, VL; Silva, RS; Torres, ILS, 2020) |
| "This study aimed to evaluate female adult offspring induced by prenatal caffeine exposure (PCE) are susceptible to non-alcoholic fatty liver disease (NAFLD) and to explore the underlying programming mechanisms." | 3.91 | Prenatal caffeine exposure increases the susceptibility to non-alcoholic fatty liver disease in female offspring rats via activation of GR-C/EBPα-SIRT1 pathway. ( Hu, S; Luo, H; Wang, H; Xia, L; Xu, D; Xu, Y; Yu, H, 2019) |
| "Our previous studies demonstrated that prenatal caffeine exposure (PCE) caused thymopoiesis inhibition, immune disorders, and airway remodeling in offspring, which raises the question of whether PCE is a risk factor for postnatal asthma." | 3.91 | Inhibition of thymocyte autophagy-associated CD4 ( Hou, LF; Liu, HX; Ping, J; Qu, W; Wen, X; Yan, HY; Zhao, WH, 2019) |
| "Few previous studies have investigated the association between prenatal caffeine intake and birth size (small for gestational age [SGA], preterm birth, and birthweight Z-score) in Japan." | 3.91 | Dose-dependent associations between prenatal caffeine consumption and small for gestational age, preterm birth, and reduced birthweight in the Japan Environment and Children's Study. ( Ait Bamai, Y; Araki, A; Itoh, S; Kishi, R; Kobayashi, S; Minatoya, M; Miyashita, C; Murata, K; Saijo, Y; Sata, F; Yamazaki, K, 2019) |
| "In addition to the pharmacological antagonism of adenosine receptors, caffeine appears to be a potent antioxidant and modulates the hyperoxia-induced pulmonary oxidative stress response and thus protective properties in the BPD-associated animal model." | 3.91 | Antioxidative effects of caffeine in a hyperoxia-based rat model of bronchopulmonary dysplasia. ( Bührer, C; Endesfelder, S; Scheuer, T; Schmitz, T; Strauß, E, 2019) |
| "Maternal antenatal, but not paternal or grandparental, caffeine intake is associated with higher offspring adiposity and obesity risk at age 5 and 9 y, with stronger associations observed for coffee caffeine." | 3.91 | Maternal, but not paternal or grandparental, caffeine intake is associated with childhood obesity and adiposity: The Lifeways Cross-Generation Cohort Study. ( Chen, LW; Kelleher, CC; Mehegan, J; Murrin, CM; Phillips, CM, 2019) |
| "To investigate the relation between pre-pregnancy caffeine and caffeinated beverage intake and risk of spontaneous abortion (SAB)." | 3.88 | Pre-pregnancy caffeine and caffeinated beverage intake and risk of spontaneous abortion. ( Chavarro, JE; Gaskins, AJ; Missmer, SA; Rich-Edwards, JW; Toth, TL; Williams, PL, 2018) |
| "The prevalence and patterns of caffeine, nicotine, medication and illicit drug intake during the first trimester of pregnancy." | 3.88 | Prevalence of xenobiotic substances in first-trimester blood samples from Danish pregnant women: a cross-sectional study. ( Aagaard, SK; Andreasen, MF; Bor, P; Larsen, A; Lesnikova, I; Telving, R; Tørring, N; Uldbjerg, N; Vestergaard, AL, 2018) |
| "The aims of this study were to identify: (i) the proportion of women exceeding the caffeine intake guideline (>200 mg/day) during each trimester, accounting for point of pregnancy awareness; (ii) guideline adherence trajectories across pregnancy; (iii) maternal characteristics associated with trajectories; and (iv) association between adherence and growth restriction birth outcomes." | 3.88 | Adherence to the Caffeine Intake Guideline during Pregnancy and Birth Outcomes: A Prospective Cohort Study. ( Allsop, S; Bruno, R; Burns, L; Elliott, E; Hutchinson, D; Mattick, RP; McCormack, C; Olsson, CA; Peacock, A; Wilson, J, 2018) |
| "To study the association between maternal caffeine intake during pregnancy and the child's weight gain and overweight risk up to 8 years." | 3.88 | Maternal caffeine intake during pregnancy and childhood growth and overweight: results from a large Norwegian prospective observational cohort study. ( Alexander, J; Bacelis, J; Botton, J; Brantsæter, AL; Elfvin, A; Haugen, M; Jacobsson, B; Meltzer, HM; Papadopoulou, E; Sengpiel, V, 2018) |
| "Several studies have reported the adverse effects of caffeine intake during pregnancy on fetal health." | 3.88 | Association Between Serum Folate Levels and Caffeinated Beverage Consumption in Pregnant Women in Chiba: The Japan Environment and Children's Study. ( Mori, C; Otake, M; Sakurai, K; Watanabe, M, 2018) |
| "Our previous in vivo studies showed that prenatal caffeine exposure (PCE) could restrain the development of chondrogenesis, which may delay fetal articular cartilage development and increase susceptibility to osteoarthritis in adults." | 3.88 | Prenatal caffeine exprosure increases adult female offspring rat's susceptibility to osteoarthritis via low-functional programming of cartilage IGF-1 with histone acetylation. ( Chen, L; Li, J; Lu, K; Magdalou, J; Ni, Q; Tan, Y; Wang, H; Zhao, Z, 2018) |
| "Epidemiologic investigations suggest that excessive intake of caffeine during pregnancy is one of the risk factors for osteoporosis in adult offspring." | 3.88 | Intrauterine Programming of Glucocorticoid-Insulin-Like Growth Factor-1 Axis-Mediated Developmental Origin of Osteoporosis Susceptibility in Female Offspring Rats with Prenatal Caffeine Exposure. ( Chen, L; Jiang, H; Magdalou, J; Qin, J; Shangguan, Y; Tan, Y; Wang, H; Wen, Y, 2018) |
| " To describe caffeine consumption during pregnancy and its association with low birth weight (LBW) and preterm birth in the birth cohort of Ribeirão Preto, state of São Paulo, Brazil, in 2010." | 3.88 | Association between Caffeine Consumption in Pregnancy and Low Birth Weight and Preterm Birth in the birth Cohort of Ribeirão Preto. ( Batista, RFL; Cardoso, VC; Cavalli, RC; Grandi, C; Simões, VMF; Vitti, FP, 2018) |
| "Objective To investigate the association between maternal caffeine intake during pregnancy and infant anthropometric measurements at age 3 and 6 months." | 3.85 | Caffeine Intake During Pregnancy in Different Intrauterine Environments and its Association with Infant Anthropometric Measurements at 3 and 6 Months of Age. ( Bernardi, JR; Bosa, VL; da Silva, CH; de Brito, ML; de Medeiros, TS; Goldani, MZ, 2017) |
| "Much of the literature on the impact of male caffeine and alcohol intake on reproductive outcomes has utilized semen quality as a proxy for male fertility, although semen parameters have a limited predictive value for spontaneous pregnancy." | 3.85 | Male caffeine and alcohol intake in relation to semen parameters and in vitro fertilization outcomes among fertility patients. ( Chavarro, JE; Chiu, YH; Gaskins, AJ; Hauser, R; Karmon, AE; Tanrikut, C; Toth, TL; Wright, DL, 2017) |
| "The pneumotach showed a linear response and clean, steady respiratory traces in which apneas and sighs were clearly visible." | 3.85 | A low cost, simplified, and scaleable pneumotachograph and face mask for neonatal mouse respiratory measurements. ( Nanu, R; Ray, RS; Sun, JJ, 2017) |
| " The objective of this study was to investigate the association between hypodontia and common environmental risk factors, such as maternal smoking and alcohol and caffeine consumption during pregnancy." | 3.85 | Maternal Smoking during Pregnancy Is Associated with Offspring Hypodontia. ( Al-Ani, AH; Antoun, JS; Farella, M; Merriman, TR; Thomson, WM, 2017) |
| "We examined the association of hypospadias risk with maternal smoking and consumption of alcohol and caffeine." | 3.85 | Maternal Smoking, Alcohol, and Caffeine Exposures and Risk of Hypospadias. ( Carmichael, SL; Ma, C; Shaw, GM, 2017) |
| "To examine the association between maternal caffeine consumption from coffee and tea during pregnancy and offspring behavioral disorders." | 3.85 | Maternal Caffeine Consumption during Pregnancy and Behavioral Disorders in 11-Year-Old Offspring: A Danish National Birth Cohort Study. ( Bech, BH; Hvolgaard Mikkelsen, S; Niclasen, J; Obel, C; Olsen, J, 2017) |
| "This study aimed to investigate the association between prenatal caffeine ingestion (PCI) and risk of postnatal pulmonary inflammation." | 3.85 | Prenatal caffeine ingestion increases susceptibility to pulmonary inflammation in adult female rat offspring. ( Chen, T; Hou, LF; Liu, HX; Liu, S; Ping, J; Qu, W; Wen, X; Yan, HY, 2017) |
| "Evidence from animal studies suggests maternal caffeine intake during pregnancy has detrimental effects on subsequent brain development in offspring." | 3.83 | Prenatal Caffeine Exposure and Child IQ at Age 5.5 Years: The EDEN Mother-Child Cohort. ( Bernard, JY; Bouvard, MP; De Agostini, M; Forhan, A; Galéra, C; Heude, B; Lioret, S; Melchior, M; van der Waerden, J, 2016) |
| "Apnea of prematurity (AOP) is nearly universal among very preterm infants, but neither the apnea burden nor its clinical associations have been systematically studied in a large consecutive cohort." | 3.83 | Clinical associations of immature breathing in preterm infants: part 1-central apnea. ( Delos, J; Fairchild, K; Kattwinkel, J; Lake, D; Mohr, M; Moorman, JR; Paget-Brown, A; Tabacaru, C, 2016) |
| "The associations of maternal caffeine intake during pregnancy with offspring growth patterns and body fat and insulin levels at school age were examined." | 3.83 | Maternal caffeine intake during pregnancy, early growth, and body fat distribution at school age. ( Franco, OH; Gaillard, R; Gishti, O; Hofman, A; Jaddoe, VW; Voerman, E, 2016) |
| "Postnatal administration of caffeine may reduce the risk of cerebral palsy (CP) in vulnerable low-birth-weight neonates." | 3.83 | Intake of Caffeinated Soft Drinks before and during Pregnancy, but Not Total Caffeine Intake, Is Associated with Increased Cerebral Palsy Risk in the Norwegian Mother and Child Cohort Study. ( Brantsæter, AL; Eichelberger, KY; Lie, RT; Meltzer, HM; Moster, D; Stoltenberg, C; Strandberg-Larsen, K; Tollånes, MC; Wilcox, AJ, 2016) |
| "Studies evaluating caffeine intake during pregnancy and long-term outcomes, such as the child's neurobehaviour, are still scarce and their results are inconsistent." | 3.83 | Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study. ( Anselmi, L; Del-Ponte, B; Matijasevich, A; Munhoz, TN; Santos, IS; Tovo-Rodrigues, L, 2016) |
| "This study does not support an increased risk of childhood obesity with increasing maternal caffeine consumption during pregnancy." | 3.81 | Maternal serum paraxanthine during pregnancy and offspring body mass index at ages 4 and 7 years. ( Keim, SA; Klebanoff, MA, 2015) |
| "Twenty-four adult Wistar rats were randomly divided into four groups, consisting of one control group and three groups that were treated with 25, 50, or 100 mg/kg of caffeine by an oral-gastric probe throughout the duration of the experimental period (pregnancy)." | 3.81 | Osteogenic potential of osteoblasts from neonatal rats born to mothers treated with caffeine throughout pregnancy. ( Goes, AM; Ocarino, Nde M; Reis, AM; Ribeiro, LG; Serakides, R, 2015) |
| "Prenatal caffeine exposure (PCE) alters the hypothalamic-pituitary-adrenocortical (HPA) axis-associated neuroendocrine metabolic programming and induces an increased susceptibility to metabolic syndrome (MS) in intrauterine growth retardation (IUGR) offspring rats." | 3.81 | Gender-specific increase in susceptibility to metabolic syndrome of offspring rats after prenatal caffeine exposure with post-weaning high-fat diet. ( Chen, L; Guo, Y; He, Z; Li, J; Luo, H; Ma, L; Magdalou, J; Wang, H; Wu, Y; Zhang, L, 2015) |
| "Although caffeine is commonly consumed during pregnancy, there are few reports on the association of in utero caffeine exposure with offspring cognition or behavior during childhood." | 3.81 | Maternal Caffeine Intake During Pregnancy and Child Cognition and Behavior at 4 and 7 Years of Age. ( Keim, SA; Klebanoff, MA, 2015) |
| "there was no difference in caffeine consumption in pregnant women with birth weight ≥2 500 g and." | 3.81 | PERINATAL OUTCOMES OF PREMATURITY AND BIRTH WEIGHT ACCORDING TO MATERNAL CAFFEINE CONSUMPTION. ( Bueno-Cavanillas, A; Del Castillo, N; Jiménez-Moleón, JJ; Martínez-Ruiz, V; Mozas, J; Olmedo-Requena, R, 2015) |
| "A high total homocysteine (tHcy) level during pregnancy is a risk factor for adverse perinatal outcomes, such as fetal growth restriction and preeclampsia." | 3.80 | Relationship between plasma total homocysteine level and dietary caffeine and vitamin B6 intakes in pregnant women. ( Haruna, M; Matsuzaki, M; Murashima, S; Murayama, R; Ota, E; Sasaki, S; Shiraishi, M; Yeo, S, 2014) |
| "Caffeine is consumed in various forms during pregnancy, has increased half-life during pregnancy and crosses the placental barrier." | 3.80 | Maternal caffeine consumption and small for gestational age births: results from a population-based case-control study. ( Browne, M; Druschel, C; Hoyt, AT; Richardson, S; Romitti, P, 2014) |
| "To investigate the effects of the maternal caffeine consumption during pregnancy to adult male testis mice offspring." | 3.80 | The testis of the mice C57/BL6 offspring in adulthood have alterations due to maternal caffeine consumption. ( Aiceles, V; Alves-Pereira, JL; Cavalcante, FS; Faria, TS; Moraes, Dde F; Ramos, Cda F, 2014) |
| "To determine if an early commencement of caffeine is associated with improved survival without bronchopulmonary dysplasia (BPD) in preterm infants." | 3.80 | Early caffeine therapy for prevention of bronchopulmonary dysplasia in preterm infants. ( Aghai, ZH; Dysart, KC; Genen, L; Greenspan, JS; Kirkby, S; Nawab, U; Taha, D, 2014) |
| " The exposures analyzed were pre-pregnancy dietary intake, pre-pregnancy and periconceptional caffeine consumption, and periconceptional cigarette smoking, alcohol drinking, and medication use." | 3.80 | Descriptive and risk factor analysis for choanal atresia: The National Birth Defects Prevention Study, 1997-2007. ( Burns, TL; Carey, JC; Druschel, CM; Kancherla, V; Lin, AE; Olney, RS; Romitti, PA; Siega-Riz, AM; Sun, L, 2014) |
| "Maternal caffeine exposure may be one of the causes for intrauterine growth retardation and low birth weight (LBW), and increased risk of type 2 diabetes mellitus (T2DM) in the adulthood has been associated with LBW." | 3.80 | Maternal caffeine exposure impairs insulin secretion by pancreatic β-cells and increases the risk of type II diabetes mellitus in offspring. ( Chan, HC; Chen, H; Guo, J; Huang, X; Jiang, X; Sha, J; Sun, T; Wang, F; Xu, Z; Zhang, J; Zhang, X, 2014) |
| "We hypothesized that caffeine improves respiratory function via an anti-inflammatory effect in lungs of a lipopolysaccharide (LPS)-induced pro-inflammatory amnionitis rat pup model." | 3.80 | Anti-inflammatory effect of caffeine is associated with improved lung function after lipopolysaccharide-induced amnionitis. ( Balan, KV; Jafri, A; Kc, P; Köroğlu, OA; MacFarlane, PM; Martin, RJ; Zenebe, WJ, 2014) |
| " The females in Group E were given caffeine orally (at 45 °C) in 30 mg/day doses from the 8th to the 21st day of pregnancy." | 3.80 | Influence of caffeine administered at 45 °C on bone tissue development. ( Burdan, F; Dworzański, W; Olchowik, G; Pańczuk, A; Tomaszewska, M; Tomaszewski, M, 2014) |
| "The aim of this study was to explore the relationships between nausea and vomiting in pregnancy and (a) fetal growth restriction; and (b) maternal caffeine metabolism and fetal growth restriction." | 3.79 | Does nausea and vomiting of pregnancy play a role in the association found between maternal caffeine intake and fetal growth restriction? ( Alwan, N; Boylan, SM; Cade, JE; Cooke, MS; Dolby, VA; Greenwood, DC; Hay, AW; Kirk, SF; Konje, JC; Potdar, N; Shires, S; Simpson, NA; Taub, N; Thomas, JD; Walker, JJ; White, KL; Wild, CP, 2013) |
| "Current knowledge suggests that laryngeal chemoreflexes (LCR) are involved in the occurrence of certain neonatal apneas/bradycardias, especially in the preterm newborn." | 3.79 | Effects of caffeine and/or nasal CPAP treatment on laryngeal chemoreflexes in preterm lambs. ( Bairam, A; Boudaa, N; Carrière, V; Germim, PS; Pasquier, JC; Praud, JP; Samson, N, 2013) |
| "There are conflicting data on the fetal safety of dietary caffeine consumption during pregnancy, particularly at levels of 300 mg/d or greater." | 3.79 | Is caffeine consumption safe during pregnancy? ( Bozzo, P; Koren, G; Morgan, S, 2013) |
| "This study was conducted to assess the association between the risks of spina bifida (SB) in relation to cigarette, alcohol, and caffeine consumption by women during the first month of pregnancy." | 3.79 | Risk of spina bifida and maternal cigarette, alcohol, and coffee use during the first month of pregnancy. ( Benedum, CM; Mitchell, AA; Werler, MM; Yazdy, MM, 2013) |
| "Estimation of the maternal caffeine intake during pregnancy and its influence on pregnancy duration, birthweight and Apgar score of the newborn." | 3.78 | Maternal caffeine intake and its effect on pregnancy outcomes. ( Jarosz, M; Siuba, M; Wierzejska, R, 2012) |
| " This study investigated the associations of cigarette smoking, caffeine intake, and vitamin intake during pregnancy with postpartum depressive symptoms at 8 weeks after childbirth." | 3.78 | Prenatal health behaviors and postpartum depression: is there an association? ( Dagher, RK; Shenassa, ED, 2012) |
| "We evaluated the relation of caffeine, coffee, tea, and sodas with time to pregnancy in a prospective cohort study of 3628 women planning a pregnancy, in Denmark (2007-2010)." | 3.78 | Caffeinated beverage and soda consumption and time to pregnancy. ( Christensen, T; Hatch, EE; Mikkelsen, EM; Riis, AH; Rothman, KJ; Sørensen, HT; Wise, LA, 2012) |
| " All but 1 mother consumed caffeine in pregnancy." | 3.78 | Maternal caffeine consumption and infant nighttime waking: prospective cohort study. ( Domingues, MR; Matijasevich, A; Santos, IS, 2012) |
| " Results suggest an additive negative effect of maternal caffeine on the fetal CV response to acute maternal hypoxia, potentially mediated via adenosine A(2A) receptor inhibition during primary cardiovascular morphogenesis." | 3.78 | Maternal hypoxia and caffeine exposure depress fetal cardiovascular function during primary organogenesis. ( Keller, BB; Momoi, N; Tinney, JP; Tobita, K, 2012) |
| "The p-PBPK model predicted the PK changes of three model compounds (namely caffeine, metoprolol and midazolam) for CYP1A2, CYP2D6 and CYP3A4 during pregnancy within twofold of observed values." | 3.78 | A pregnancy physiologically based pharmacokinetic (p-PBPK) model for disposition of drugs metabolized by CYP1A2, CYP2D6 and CYP3A4. ( Abduljalil, K; Gaohua, L; Jamei, M; Johnson, TN; Rostami-Hodjegan, A, 2012) |
| "Human studies that have investigated the association between caffeine intake during pregnancy and offspring's behavioral outcomes are scant and inconclusive." | 3.78 | Caffeine intake during pregnancy and risk of problem behavior in 5- to 6-year-old children. ( Hofland, L; Koot, HM; Loomans, EM; Van den Bergh, BR; van der Stelt, O; van der Wal, MF; Vrijkotte, TG, 2012) |
| "Caffeine intake has been suggested to be associated with the risk of hypertension." | 3.77 | Maternal caffeine intake, blood pressure, and the risk of hypertensive complications during pregnancy. The Generation R Study. ( Bakker, R; Hofman, A; Jaddoe, VW; Raat, H; Steegers, EA, 2011) |
| "8 for total maternal dietary caffeine intake or specific types of caffeinated beverages and anotia/microtia, esophageal atresia, small intestinal atresia, and craniosynostosis; however, dose-response patterns were absent." | 3.77 | Maternal caffeine intake and risk of selected birth defects in the National Birth Defects Prevention Study. ( Browne, ML; Druschel, CM; Feldkamp, ML; Hoyt, AT; Marshall, EG; Rasmussen, SA; Romitti, PA, 2011) |
| "Outside pregnancy, acute caffeine consumption is associated with insulin resistance." | 3.77 | Caffeine and insulin resistance in pregnancy. ( Catov, J; Laughon, SK; Parana, S; Powers, RW; Roberts, JM, 2011) |
| "The objective of this study was to examine whether the risk of sine causa recurrent miscarriage is associated with caffeine consumption during the periconceptional period and early gestation after controlling for pregnancy-related symptoms." | 3.77 | Maternal caffeine consumption and sine causa recurrent miscarriage. ( Caramellino, L; Menato, G; Patriarca, A; Stefanidou, EM, 2011) |
| "Caffeine is a commonly consumed drug during pregnancy with the potential to affect the developing fetus." | 3.76 | Caffeine intake during pregnancy, late miscarriage and stillbirth. ( Alwan, N; Boylan, S; Cade, JE; Charvill, J; Chipps, KC; Cooke, MS; Dolby, VA; Greenwood, DC; Hay, AW; Kassam, S; Kirk, SF; Konje, JC; Potdar, N; Shires, S; Simpson, N; Taub, N; Thomas, JD; Walker, J; White, KL; Wild, CP, 2010) |
| " Additionally, the mothers of these infants were asked to identify their smoking habits and/or caffeine consumption during pregnancy through face-to-face interviews." | 3.76 | A study on neonatal factors and eruption time of primary teeth. ( Aktoren, O; Gokcay, G; Guven, Y; Tuna, EB, 2010) |
| "We examined the associations of maternal caffeine intake, on the basis of coffee and tea consumption, with fetal growth characteristics measured in each trimester of pregnancy and the risks of adverse birth outcomes." | 3.76 | Maternal caffeine intake from coffee and tea, fetal growth, and the risks of adverse birth outcomes: the Generation R Study. ( Bakker, R; Hofman, A; Jaddoe, VW; Obradov, A; Raat, H; Steegers, EA, 2010) |
| "Investigations of maternal caffeine intake and neural tube defects (NTDs) have not considered genetic influences." | 3.76 | Caffeine, selected metabolic gene variants, and risk for neural tube defects. ( Browne, ML; Burns, TL; Druschel, CM; Murray, JC; Olney, RS; Romitti, PA; Schmidt, RJ, 2010) |
| "Moderate caffeine consumption (less than 200 mg per day) does not appear to be a major contributing factor in miscarriage or preterm birth." | 3.76 | ACOG CommitteeOpinion No. 462: Moderate caffeine consumption during pregnancy. ( , 2010) |
| "To determine effects of 2 doses of caffeine on metabolic variables in neonatal pigs with peripartum asphyxia." | 3.76 | Effects of administration of caffeine on metabolic variables in neonatal pigs with peripartum asphyxia. ( Becerril-Herrera, M; Bonilla-Jaime, H; Hernández-González, R; Mota-Rojas, D; Orozco-Gregorio, H; Trujillo-Ortega, ME; Villanueva-García, D, 2010) |
| "This study evaluated the effect of caffeine consumption on the success rate of pregnancy and various in vitro fertilization (IVF) performance parameters." | 3.76 | The effect of caffeine consumption on the success rate of pregnancy as well various performance parameters of in-vitro fertilization treatment. ( Al-Saleh, I; Coskun, S; El-Doush, I; Grisellhi, B, 2010) |
| "The aim of this analysis of the study 'Breast-feeding habits in Bavaria' is to describe the smoking habits, alcohol and caffeine consumption of mothers in Bavaria before, during and after pregnancy." | 3.75 | [Smoking, alcohol and caffeine consumption of mothers before, during and after pregnancy--results of the study 'breast-feeding habits in Bavaria']. ( Fromme, H; Kohlhuber, M; Koletzko, B; Rebhan, B; Schwegler, U, 2009) |
| " Maternal consumption of coffee and other caffeine-containing beverages in early pregnancy was recorded shortly after birth." | 3.75 | Maternal consumption of coffee and caffeine-containing beverages and oral clefts: a population-based case-control study in Norway. ( Andersen, LF; Drevon, CA; Johansen, AM; Lie, RT; Wilcox, AJ, 2009) |
| "Moderate caffeine intake during pregnancy is common, but little is known about its potential association with birth defects." | 3.75 | Maternal caffeine intake during pregnancy and orofacial clefts. ( Browne, ML; Collier, SA; Honein, MA; Rasmussen, SA, 2009) |
| "Caffeine has relevance for women's health and pregnancy, including significant associations with spontaneous abortion and low birth weight." | 3.75 | Caffeine's implications for women's health and survey of obstetrician-gynecologists' caffeine knowledge and assessment practices. ( Anderson, BL; Juliano, LM; Schulkin, J, 2009) |
| "Associations between maternal caffeine consumption and neural tube defects (NTDs) by type of NTD (anencephaly, spina bifida, or encephalocele) were examined using data from the National Birth Defects Prevention Study (NBDPS)." | 3.75 | Maternal caffeine consumption and risk of neural tube defects. ( Browne, ML; Burns, TL; Druschel, CM; Olney, RS; Romitti, PA; Schmidt, RJ, 2009) |
| " Currently published data has been stressed that the metyloxantine consumption increases the risk of coronary heart disease, arterial hypertension, arterial stiffness, and an elevation of cholesterol and homocysteine plasma concentration." | 3.75 | [Side effects of caffeine]. ( Burdan, F; Dworzański, W; Opielak, G, 2009) |
| "In Denmark chlorobutanol-caffeine rectal suppositories are prescribed by some obstetric departments for the treatment of hyperemesis gravidarum." | 3.74 | [The treatment of hyperemesis gravidarum with chlorobutanol-caffeine rectal suppositories in Denmark: practice and evidence]. ( Brødbaek, HB; Damkier, P, 2007) |
| "No significant associations were seen between intrauterine exposure to alcohol or caffeine and a diagnosis of endometriosis." | 3.74 | Intrauterine exposures and risk of endometriosis. ( Buck Louis, GM; Hediger, ML; Peña, JB, 2007) |
| " Maternal urine throughout pregnancy and umbilical cord blood samples were analyzed for caffeine, paraxanthine, theophylline, and theobromine." | 3.74 | Prenatal caffeine assessment: fetal and maternal biomarkers or self-reported intake? ( Benowitz, NL; Bracken, MB; Grosso, LM; Triche, E, 2008) |
| "Women were recruited before or early in pregnancy and interviewed regarding sources of caffeine, including assessment of changes over the perinatal period." | 3.74 | Caffeine and miscarriage risk. ( Chan, RL; Hartmann, KE; Herring, AH; Howards, PP; Savitz, DA, 2008) |
| "The objective of the study was to examine whether the risk of miscarriage is associated with caffeine consumption during pregnancy after controlling for pregnancy-related symptoms." | 3.74 | Maternal caffeine consumption during pregnancy and the risk of miscarriage: a prospective cohort study. ( Li, DK; Odouli, R; Weng, X, 2008) |
| "Caffeine consumption during pregnancy is reported to increase the risk of in utero growth restriction and spontaneous abortion." | 3.74 | Modest maternal caffeine exposure affects developing embryonic cardiovascular function and growth. ( Elshershari, H; Hoffmann, PJ; Keller, BB; Liu, LJ; Momoi, N; Ralphe, JC; Tinney, JP; Tobita, K, 2008) |
| "To examine the association of maternal caffeine intake with fetal growth restriction." | 3.74 | Maternal caffeine intake during pregnancy and risk of fetal growth restriction: a large prospective observational study. ( , 2008) |
| "There are lingering concerns about caffeine consumption during pregnancy or the early postnatal period, partly because there may be long-lasting behavioral changes after caffeine exposure early in life." | 3.74 | Perinatal caffeine, acting on maternal adenosine A(1) receptors, causes long-lasting behavioral changes in mouse offspring. ( Björklund, O; Fredholm, BB; Kahlström, J; Salmi, P, 2008) |
| "The aim of this work was to study whether caffeine or theophylline chronically consumed during pregnancy affect inhibitory adenylyl cyclase pathway mediated by adenosine, in rat brain of both mothers and full-term fetuses." | 3.73 | Chronic caffeine or theophylline intake during pregnancy inhibits A1 receptor function in the rat brain. ( Albasanz, JL; León, D; Martín, M; Ruíz, MA, 2005) |
| "Some case-control studies have demonstrated that caffeine intake and high CYP1A2 activity increase risks of recurrent pregnancy loss (RPL) but the multifactorial effect is obscure." | 3.73 | Caffeine intake, CYP1A2 polymorphism and the risk of recurrent pregnancy loss. ( Kato, EH; Kishi, R; Minakami, H; Morikawa, M; Saijo, Y; Sata, F; Suzuki, K; Yamada, H, 2005) |
| "The NAT acetylator status was determined by measuring urinary caffeine metabolites in 134 nonpregnant women with a history of preeclampsia and in 109 control women with uncomplicated pregnancy." | 3.73 | N-acetyl-transferase phenotype and risk for preeclampsia. ( Peters, WH; Raijmakers, MT; Roes, EM; Steegers, EA; Steegers-Theunissen, RP; te Morsche, RH; Zusterzeel, PL, 2005) |
| "The purpose of the study was to examine whether caffeine dependence and a family history of alcoholism are associated with continued use of caffeine during pregnancy." | 3.73 | Caffeine dependence in combination with a family history of alcoholism as a predictor of continued use of caffeine during pregnancy. ( Berger, N; Griffiths, RR; Haug, NA; Svikis, DS, 2005) |
| " In comparison with not drinkers, all the ORs of overall intake of caffeine were closed near the unity for both SGA and NGA preterm birth." | 3.73 | Coffee drinking and risk of preterm birth. ( Chatenoud, L; Chiaffarino, F; Chiantera, V; Fedele, L; Maffioletti, C; Parazzini, F; Ricci, E; Tozzi, L, 2006) |
| "The objective of this study was to examine the association between caffeine intake during pregnancy and fetal mortality in Montevideo, the capital city of Uruguay, taking into account several potential confounding factors." | 3.73 | Maternal caffeine consumption and fetal death: a case-control study in Uruguay. ( Barros, FC; Matijasevich, A; Santos, IS; Yemini, A, 2006) |
| "Apnea of prematurity develop during the first days of life and usually resolve by the time the infant reaches 36-37 weeks postmenstrual age." | 3.73 | [Apnea of prematurity: risk factors and ambulatory treatment with caffeine citrate]. ( Baudon, JJ; Biran-Mucignat, V; Boelle, PY; Ducrocq, S; Gold, F; Lebas, F, 2006) |
| "02% caffeine in water as drinking fluid during the whole period of pregnancy." | 3.72 | Consequences of in utero caffeine exposure on respiratory output in normoxic and hypoxic conditions and related changes of Fos expression: a study on brainstem-spinal cord preparations isolated from newborn rats. ( Bach, V; Bodineau, L; Cayetanot, F; Collin, T; Frugière, A; Gros, F; Lebleu, A; Sådani-Makki, F, 2003) |
| "Whether caffeine consumption during pregnancy represents a fetal hazard remains uncertain." | 3.72 | Association of maternal caffeine consumption with decrements in fetal growth. ( Belanger, K; Bracken, MB; Hellenbrand, K; Leaderer, BP; Triche, EW, 2003) |
| "Consumption of 5 or more units alcohol per week and 375 mg or more caffeine per day during pregnancy may increase the risk of spontaneous abortion." | 3.72 | Cigarette, alcohol, and caffeine consumption: risk factors for spontaneous abortion. ( Rasch, V, 2003) |
| "The aim of this study was to determine the effects of tobacco use and consumption of caffeine in pregnancy on the fetus and placenta by measuring the body weights, head circumferences, and lengths of newborns, and also weights and diameters of placentas." | 3.72 | The effect of smoking and caffeine on the fetus and placenta in pregnancy. ( Balat, A; Balat, O; Pençe, S; Ugur, MG, 2003) |
| "Caffeine is frequently used during pregnancy and associated with teratogenic effects, such as low birth weight, hearth and digital defects, cleft palate and abortion with fetal loss." | 3.72 | High dose of caffeine administered to pregnant rats causes histopathological changes in the cornea of newborn pups. ( Alasehirli, B; Bagci, C; Balat, Z; Cengiz, B; Evereklioglu, C; Güldür, E; Sari, I, 2003) |
| "We studied the level of oxidative DNA damage in terms of 7-hydro-8-oxo-2'-deoxyguanosine (8-oxodG) in sperm DNA among 225 first-pregnancy planners." | 3.72 | Oxidative DNA damage in human sperm influences time to pregnancy. ( Bonde, JP; Ernst, E; Giwercman, A; Gyllemborg, J; Hjollund, NH; Kold-Jensen, T; Loft, S; Olsen, J; Poulsen, HE; Scheike, T, 2003) |
| "Although chronic caffeine exposure during pregnancy has been shown to affect fetal growth, adverse effects of caffeine on embryogenesis are not only well understood, but also controversial." | 3.72 | Caffeine enhances the expression of the angiotensin II Type 2 receptor mRNA in BeWo cell culture and in the rat placenta. ( Abiko, Y; Gottschalk, S; Ide, I; Nakamoto, T; Saito, S; Sasahara, H; Tanuma, A; Yazdani, M, 2003) |
| "Evidence for a harmful effect of caffeine intake on risk of miscarriage (spontaneous abortion) is inconsistent and nausea during pregnancy has been claimed to explain any association seen." | 3.72 | The effect of caffeine consumption and nausea on the risk of miscarriage. ( Doyle, P; Giannelli, M; Hermon, C; Pelerin, M; Roman, E, 2003) |
| "It has been suggested that a high caffeine intake in pregnancy may be a risk factor for fetal growth retardation." | 3.72 | High caffeine consumption in the third trimester of pregnancy: gender-specific effects on fetal growth. ( Bakketeig, LS; Jacobsen, G; Lund-Larsen, K; Trygg, KU; Vik, T, 2003) |
| "Consumption of caffeine and alcohol is suspected to affect pregnancy outcome." | 3.72 | Does caffeine and alcohol intake before pregnancy predict the occurrence of spontaneous abortion? ( Bergholt, T; Grønbaek, M; Kjaer, SK; Madsen, LB; Munk, C; Ottesen, B; Tolstrup, JS, 2003) |
| "To test the hypothesis that, in women with type 1 diabetes, prenatal smoking and caffeine consumption during pregnancy are associated with an increased risk of adverse maternal and perinatal outcomes." | 3.72 | Consequences of smoking and caffeine consumption during pregnancy in women with type 1 diabetes. ( Buncher, CR; Kalkwarf, H; Khoury, JC; Khoury, PR; McElvy, S; Miodovnik, M; Sibai, B, 2004) |
| "Chronic caffeine exposure during pregnancy has an effect on fetal growth; however, the adverse effects of caffeine on embryogenesis are not well understood and controversial." | 3.72 | Caffeine suppresses the expression of the Bcl-2 mRNA in BeWo cell culture and rat placenta. ( Abiko, Y; Ide, K; Kamino, Y; Nakamoto, T; Nomura, K; Saito, S; Sasahara, H, 2004) |
| "Signals of early pregnancy included an aversion to coffee in addition to nausea and vomiting, which resulted in decreased caffeine consumption." | 3.72 | Changes in caffeine consumption as a signal of pregnancy. ( Lawson, CC; LeMasters, GK; Wilson, KA, 2004) |
| "Excessive maternal caffeine exposure during pregnancy had cataractogenic effects on developing crystalline lenses in newborn rat eyes, both macroscopically and histopathologically." | 3.72 | Excessive maternal caffeine exposure during pregnancy is cataractogenic for neonatal crystalline lenses in rats: a biomicroscopic and histopathologic study. ( Alasehirli, B; Cengiz, B; Evereklioglu, C; Güldür, E; Pirbudak, L; Sari, I, 2004) |
| "Excessive ingestion of caffeine can induce hypokalemia, which affects the neuromuscular system and can lead to paralysis." | 3.71 | Caffeine-induced hypokalemic paralysis in pregnancy. ( Appel, CC; Myles, TD, 2001) |
| "This study estimates the effect of maternal caffeine consumption throughout pregnancy on fetal growth." | 3.71 | Maternal caffeine intake and intrauterine growth retardation. ( Belanger, K; Bracken, MB; Grosso, LM; Leaderer, B; Rosenberg, KD; Saftlas, AF, 2001) |
| " 1990) established that caffeine, when administered during pregnancy, significantly inhibited the differentiation of the seminiferous cords and subsequent Leydig cell development in the interstitium." | 3.71 | Effects of caffeine and its reactive metabolites theophylline and theobromine on the differentiating testis. ( Locquet, O; Magre, S; Pollard, I; Solvar, A, 2001) |
| "Epidemiologic studies have been unable to conclusively evaluate whether caffeine intake during pregnancy is associated with reduced birth weight and/or fetal growth restriction." | 3.71 | Effect of caffeine exposure during pregnancy on birth weight and gestational age. ( Clausson, B; Cnattingius, S; Ekbom, A; Granath, F; Lundgren, S; Nordmark, A; Signorello, LB, 2002) |
| "To assess the association between maternal caffeine consumption during pregnancy and low birth weight, prematurity and intrauterine growth retardation." | 3.71 | [Birthweight and caffeine consumption]. ( Barros Filho, Ade A; Bicalho, GG, 2002) |
| "Pregnant rats were treated daily with 1 g/L of caffeine or theophylline in their drinking water during pregnancy and the effect of these methylxanthines on adenosine A1 receptor was assayed using binding and reverse transcription polymerase chain reaction (RT-PCR) assays in brains from both mothers and full-term fetuses." | 3.71 | Adenosine A1 receptor down-regulation in mothers and fetal brain after caffeine and theophylline treatments to pregnant rats. ( Albasanz, JL; Fernández, M; León, D; Martín, M; Ruíz, MA, 2002) |
| "Previous studies of maternal caffeine use and pregnancy outcome have relied on self-reported use." | 3.70 | Serum caffeine and paraxanthine as markers for reported caffeine intake in pregnancy. ( Clemens, JD; Dersimonian, R; Klebanoff, MA; Levine, RJ; Wilkins, DG, 1998) |
| "To examine the association between maternal caffeine consumption during pregnancy and the risk of sudden infant death syndrome (SIDS)." | 3.70 | Heavy caffeine intake in pregnancy and sudden infant death syndrome. New Zealand Cot Death Study Group. ( Ford, RP; Mitchell, EA; Schluter, PJ; Scragg, R; Stewart, AW; Taylor, BJ, 1998) |
| "The authors conducted a matched case-control study to investigate the effects of caffeine intake during pregnancy on birth weight." | 3.70 | Caffeine intake and low birth weight: a population-based case-control study. ( Carvalhal, JB; Huttly, S; Santos, IS; Victora, CG, 1998) |
| " She developed post-dural puncture headache (PDPH) on the third postpartum day which was managed by palliative measures: bed rest (patient's position of choice), increased hydration (water: 3 litres po per day), lysine acetyl salicylate (5." | 3.70 | Unilateral trigeminal and facial nerve palsies associated with epidural analgesia in labour. ( Agustí, M; Carrero, EJ; Fábregas, N; Fernández, C; Valldeoriola, F, 1998) |
| "The crude ORs for caffeine consumption > 800 mg/24 hours both during and after pregnancy were significantly raised: 3." | 3.70 | Caffeine and alcohol as risk factors for sudden infant death syndrome. Nordic Epidemiological SIDS Study. ( Alm, B; Helweg-Larsen, K; Irgens, LM; Lagercrantz, H; Norvenius, G; Oyen, N; Skjaerven, R; Wennergren, G, 1999) |
| "Whether the consumption of caffeine during pregnancy increases the risk of spontaneous abortion is controversial." | 3.70 | Maternal serum paraxanthine, a caffeine metabolite, and the risk of spontaneous abortion. ( Clemens, JD; DerSimonian, R; Klebanoff, MA; Levine, RJ; Wilkins, DG, 1999) |
| "Pregnant ICR mice were exposed to caffeine at levels of 0, 4, 20 and 100 mg/kg during pregnancy." | 3.70 | [Behavioral-teratological effects of caffeine on mice]. ( Li, H; Peng, L; Yin, W, 1998) |
| "Motherisk's recent meta-analysis suggests that the risks for miscarriage and fetal growth retardation increase only with daily doses of caffeine above 150 mg/d, equivalent to six typical cups of coffee a day." | 3.70 | Caffeine during pregnancy? In moderation. ( Koren, G, 2000) |
| "There is considerable concern over the widespread use of caffeine during and after pregnancy." | 3.69 | The effect of long term caffeine treatment on hypoxic-ischemic brain damage in the neonate. ( Adén, U; Bona, E; Fredholm, BB; Hagberg, H, 1995) |
| "Pregnant Yorkshire gilts (n = 42) were fed caffeine (6 g/d) or served as controls from d 60 of pregnancy until d 4 postpartum to test the effect of caffeine on mammary gland development, milk yield, and feed consumption." | 3.69 | The effect of caffeine on mammary gland development and milk yield in primiparous sows. ( Hacker, RR; Li, S, 1995) |
| "Dose-response of the teratogenic effect of caffeine (CA) and the potential role of facial hematomas in the pathogenesis of caffeine-induced cleft palate were investigated using CD1 mice treated with 150, 200, or 250 mg CA/kg i." | 3.69 | Interaction of dimethylsulfoxide and arachidonic acid with the teratogenic effects of caffeine in mice. ( Brimer, GE; Fraipier, BL; Frappier, BL; Reddy, CS; Reddy, RV, 1994) |
| " Alcohol and caffeine consumption by the mothers during pregnancy were both significantly associated with elevated IgE concentration." | 3.69 | Several genetic and environmental factors influence cord blood IgE concentration. ( Bjerke, T; Hedegaard, M; Henriksen, TB; Nielsen, BW; Schiøtz, PO, 1994) |
| "35 mg/ml of caffeine prior to and throughout pregnancy." | 3.69 | In utero caffeine exposure affects feeding pattern and variable ratio performance in infant monkeys. ( Gilbert, SG; Rice, DC, 1994) |
| "To examine the association of plasma caffeine concentrations during pregnancy with fetal growth and to compare this with relations with reported caffeine intake." | 3.69 | Relation of caffeine intake and blood caffeine concentrations during pregnancy to fetal growth: prospective population based study. ( Anderson, HR; Bland, JM; Carey, IM; Cook, DG; Feyerabend, C; Jarvis, MJ; Peacock, JL, 1996) |
| "In this study, fetal joint abnormalities caused by cytosine arabinoside, caffeine, sodium salicylate, and retinyl acetate administration during pregnancy, were investigated." | 3.69 | Demonstration of congenital anomalies in the joints of the forelimbs and hindlimbs caused by several pharmacological agents. ( Erdoğan, D; Kadioğlu, D; Peker, T, 1996) |
| "The aim of this study was to examine the effect of caffeine consumption during pregnancy on birth weight and its possible interaction with smoking." | 3.69 | Effect of caffeine intake during pregnancy on birth weight. ( Adanja, BJ; Marinković, JM; Petrović, RR; Sipetić, SB; Vlajinac, HD, 1997) |
| "The present study was designed to investigate the mechanism(s) underlying previously observed birth weight differences found in the first litter of the second (F2) generation bred from caffeine-exposed F1 females." | 3.68 | Caffeine-mediated effects on reproductive health over two generations in rats. ( Claassens, R; Pollard, I, 1992) |
| " Group 3 dams were fed a 20% protein diet supplemented with caffeine (2 mg/100 g body weight) and dams of group 4 were fed a 20% protein diet supplemented with both caffeine and zinc." | 3.68 | Relationship of prenatal caffeine exposure and zinc supplementation on fetal rat brain growth. ( Fontenot, F; Gottschalk, SB; Joseph, F; Kanemaru, Y; Nakamoto, T; Yazdani, M, 1992) |
| " The growth of cardiac cells derived from newborn rats whose dams were either malnourished or malnourished with caffeine during pregnancy was inhibited in culture over the period of 5 days as compared to that of the normally nourished cells." | 3.68 | Effects of caffeine on the DNA and protein synthesis of the protein-energy malnourished neonatal cardiac muscle cells in culture. ( Kanemaru, Y; Nakamoto, T; Narayanan, CH; Rossowska, MJ; Yazdani, M; Yoshino, S, 1992) |
| "To assess the prevalence of smoking and of caffeine and alcohol intake during pregnancy in a northern population and to determine the relation of these factors to birth weight, length and head circumference." | 3.68 | Smoking and caffeine and alcohol intake during pregnancy in a northern population: effect on fetal growth. ( Froese, GJ; Godel, JC; Hodges, PE; Joffres, MR; Johnson, KE; Pabst, HF, 1992) |
| "Mice were administered caffeine (500 mg/liter of drinking water) from d 1 until d 18 of pregnancy." | 3.68 | Caffeine administered during pregnancy augments subsequent lactation in mice. ( Sheffield, LG, 1991) |
| "In a previous paper, I have proposed that the deficiency of an endogenous caffeine-like substance is the underlying pathogenic mechanism in schizophrenia (1)." | 3.68 | Exploring the role of an endogenous caffeine-like substance in the pathogenesis of schizophrenia. ( Missak, SS, 1991) |
| "Taken together with studies reporting similar findings, these results suggest that heavy caffeine consumption increases the risk for fetal growth retardation." | 3.68 | Caffeine consumption during pregnancy and fetal growth. ( Eskenazi, B; Fenster, L; Swan, SH; Windham, GC, 1991) |
| " We analyzed data on 607 cases and 1,284 controls to evaluate the potential association between caffeine consumption during the first trimester of pregnancy and spontaneous abortion." | 3.68 | Caffeine consumption during pregnancy and spontaneous abortion. ( Eskenazi, B; Fenster, L; Swan, SH; Windham, GC, 1991) |
| " The methylxanthines; caffeine, theophylline and theobromine, were administered via drinking water in the proportions occurring in tea, at a dose of 50, 1 and 2 mg/kg body-weight respectively to Wistar albino rats throughout pregnancy and for up to the 14th day of lactation." | 3.68 | The effect of methylxanthines on milk volume and composition, and growth of rat pups. ( Grimble, RF; Hart, AD, 1990) |
| "In this manuscript it is demonstrated that caffeine when administered to the rat (30 mg/kg per day) during pregnancy affected certain aspects of normal sexual differentiation of the fetal gonads." | 3.68 | Influence of caffeine administered during pregnancy on the early differentiation of fetal rat ovaries and testes. ( Magre, S; Pollard, I; Williamson, S, 1990) |
| "04% caffeine in the drinking fluid ad libitum before and/or during pregnancy throughout the lactational period, were examined on days 1, 5 and 10." | 3.68 | Maternal caffeine ingestion increases the tyrosine level in neonatal rat cerebrum. ( Nakazawa, K; Tanaka, H, 1990) |
| "Whether caffeine intake during pregnancy is related to intrauterine growth retardation, low birth weight, and preterm birth remains unclear." | 3.68 | Relation of caffeine intake during pregnancy to intrauterine growth retardation and preterm birth. ( Beaulac-Baillargeon, L; Fortier, I; Marcoux, S, 1993) |
| "To examine the relationship between caffeine consumption during pregnancy and the occurrence of spontaneous abortion and intrauterine growth retardation." | 3.68 | Moderate caffeine use and the risk of spontaneous abortion and intrauterine growth retardation. ( Aarons, JH; Brown, ZA; Conley, MR; Graubard, BI; Holmes, LB; Jovanovic-Peterson, LG; Knopp, RH; Metzger, BE; Mills, JL; Simpson, JL, 1993) |
| "To investigate the effects of smoking, alcohol, and caffeine consumption and socio-economic factors and psychosocial stress on birth weight." | 3.67 | Effects on birth weight of smoking, alcohol, caffeine, socioeconomic factors, and psychosocial stress. ( Anderson, HR; Bland, JM; Brooke, OG; Peacock, JL; Stewart, CM, 1989) |
| "Alcohol and caffeine consumption during pregnancy are risk factors for fetal outcome." | 3.67 | Neural tube defects in early rat embryos following maternal treatment with ethanol and caffeine. ( Persaud, TV; Ross, CP, 1989) |
| " Comparison of the groups using quantitative measures of apnea, bradycardia, and periodic breathing obtained from pneumogram analysis and the incidence of monitor alarms on bedside nursing records showed no significant differences." | 3.67 | Transplacentally acquired caffeine and the occurrence of apnea, bradycardia, and periodic breathing in preterm infants: preliminary communication. ( Braun, RJ; Evans, MA; Kelly, DH; McCulloch, KM; Simms, PE, 1989) |
| "Since it is unknown if chemicals which are generally safe in pregnancy can potentiate the embryotoxicity of cytotoxic drugs before implantation, the combined effects of cyclophosphamide (CPA) and caffeine (CF) were studied in the mouse (day 2) with CPA at 20 mg/kg, which induces a 18% resorption rate, and CF at 100 mg/kg, which does not increase embryolethality." | 3.67 | Potentiating effect of caffeine on embryotoxicity of cyclophosphamide treatment in vivo during the preimplantation period. ( Spielmann, H; Vogel, R, 1987) |
| " In line with this hypothesis, it was found that three functional benzodiazepine antagonists (FG 7142, pentylenetetrazol, caffeine) decreased food intake, lowered aggression and strengthened freezing in lactating mother rats." | 3.67 | Behavioural similarities between mother rats and benzodiazepine-treated non-maternal animals. ( Ferreira, A; Hansen, S; Selart, ME, 1985) |
| "The mandibles and long bones of newborn rats were analyzed for the effects of maternal caffeine consumption and protein-energy malnutrition." | 3.67 | Protein-energy malnutrition in rats during pregnancy modifies the effects of caffeine on fetal bones. ( Nakamoto, T; Shaye, R, 1986) |
| " Dams of groups 2 and 3 were fed the control diet supplemented with caffeine (1 mg and 2 mg/100 g body weight, respectively)." | 3.67 | Effects of different levels of caffeine supplemented to the maternal diet on the brains of newborn rats and their dams. ( Hartman, AD; Joseph, F; Nakamoto, T; Yazdani, M, 1988) |
| "Ergotamine exposure during pregnancy has been suggested to cause birth defects which have a vascular disruptive aetiology." | 3.67 | Birth defects following maternal exposure to ergotamine, beta blockers, and caffeine. ( Goldstein, DA; Hughes, HE, 1988) |
| "Caffeine, when administered in moderate (30 mg/kg X d) or high (60 mg/kg X d) doses during pregnancy, was shown to cause significant fetal growth retardation of both sexes." | 3.67 | Effects of caffeine administered during pregnancy on fetal development and subsequent function in the adult rat: prolonged effects on a second generation. ( Jabbour, H; Mehrabani, PA; Pollard, I, 1987) |
| "From day 6 to day 20 of pregnancy, rats were treated with caffeine in a total daily dose of 10 or 100 mg/kg by gavage, either as a single bolus dose or as four divided doses given at 3-hr intervals throughout the day." | 3.67 | Effects of administering caffeine to pregnant rats either as a single daily dose or as divided doses four times a day. ( McElhatton, PR; Smith, SE; Sullivan, FM, 1987) |
| "02% caffeine in drinking water ad libitum before and/or during pregnancy were examined on gestational day 21." | 3.67 | Effects of maternal caffeine ingestion on the perinatal cerebrum. ( Arima, M; Nakazawa, K; Tanaka, H, 1987) |
| "The possible effects of long- and short-term maternal ingestion of caffeine during normal human pregnancy on the breathing and body movements of third-trimester fetuses were studied in 14 patients, selected by a dietary questionnaire, and divided into two equal groups: high consumers (greater than 500 mg/day) (group 1) and low consumers (less than 250 mg/day) (group 2)." | 3.67 | The effects of long- and short-term maternal caffeine ingestion on human fetal breathing and body movements in term gestations. ( Altman, R; Devoe, LD; McGowan, J; Searle, N, 1987) |
| "The elimination of caffeine from plasma and the excretion of the main metabolites of metamizol (noramidopyrinemethanesulphonate sodium) into the urine were determined in healthy pregnant women (weeks 30-38 of pregnancy) and in patients with intrahepatic cholestasis in pregnancy (weeks 28-39 of pregnancy)." | 3.67 | [The effect of intrahepatic cholestasis in pregnancy on various forms of cytochrome P-450-dependent biotransformation reactions]. ( Ortweiler, W; Peiker, G; Siegert, C; Splinter, FK; Traeger, A, 1987) |
| "The caffeine-induced changes in contractility of early human fetal hearts obtained from termination of pregnancy and surviving in nutrient solution was studied." | 3.67 | [Effect of caffeine on the contractility of the fetal heart muscle]. ( Gyöngyösi, J; Papp, JG; Resch, BA, 1987) |
| "The influence of caffeine and cigarette consumption on fetal growth during pregnancy was studied retrospectively in 913 newborn infants." | 3.67 | Caffeine-cigarette interaction on fetal growth. ( Beaulac-Baillargeon, L; Desrosiers, C, 1987) |
| "To evaluate the relationship of antecedent maternal smoking and caffeine consumption habits on the occurrence of apnea in their offspring, rates for central and obstructive apnea were analyzed in a cohort of mother-infant pairs." | 3.67 | Effects of maternal smoking and caffeine habits on infantile apnea: a retrospective study. ( Bendell, D; Duke, JC; Mattice, CD; McCaffree, MA; Orr, WC; Toubas, PL, 1986) |
| "Characterization of alterations in caffeine elimination during pregnancy is essential in assessing the potential exposure of the fetus to caffeine and its metabolites." | 3.67 | Elimination of chronically consumed caffeine in the pregnant monkey (Macaca fascicularis). ( Geoffroy, S; Gilbert, SG; Klassen, RD; Rice, DC; So, Y; Stavric, B, 1986) |
| "Fetal death in a primigravid patient who had taken an overdose of ergotamine tartrate is presented." | 3.67 | Intrauterine death from ergotamine overdosage. ( Au, KL; Wong, VC; Woo, JS, 1985) |
| "In a prospective cohort study, 3135 pregnant women were followed to evaluate the association of caffeine consumption during pregnancy with late first- and second-trimester spontaneous abortion." | 3.67 | Caffeine consumption during pregnancy and association with late spontaneous abortion. ( Bracken, MB; Srisuphan, W, 1986) |
| "Within the framework of a study on the course of pregnancy, a cohort of 996 Swiss mothers was interviewed upon admission for delivery at Aarau Maternity Hospital regarding nicotine, alcohol, caffeine and narcotics consumption." | 3.67 | [The course of pregnancy in a representative Swiss sample (Aarau Pregnancy and Newborn Infant Study). II. Stimulants in pregnancy]. ( Bruppacher, R; Bürgi, W; Fricker, HS; Gugler, E; Kaufmann, H; Kipfer, H, 1985) |
| "After literature reports linking fibrocystic breast disease (FBD) to methylxanthine ingestion, a pilot study was undertaken to investigate the possible contribution of theophylline to this effect." | 3.67 | Theophylline and fibrocystic breast disease. ( Bullough, B; Hindi-Alexander, MC; London, WM; Middleton, E; Montes, N; Rosner, DH; Zielezny, MA, 1985) |
| "We studied the effects of caffeine ingestion during pregnancy." | 3.67 | Effects of caffeine ingestion during pregnancy. ( Furuhashi, N; Hiruta, M; Sato, S; Suzuki, M; Takahashi, T; Tanaka, M, 1985) |
| "Caffeine disposition was studied over 24 h in rats on the 12th day of pregnancy given 80 mg/kg of drug as a single oral dose or in four divided doses every three hours." | 3.67 | Caffeine disposition after oral administration to pregnant rats. ( Bonati, M; Bortolotti, A; Gaspari, F; Jiritano, L, 1985) |
| "We studied whether protein-energy malnutrition changed brain susceptibility to a small dose of caffeine in newborn rats." | 3.67 | Protein-energy malnutrition during pregnancy alters caffeine's effect on brain tissue of neonate rats. ( Mori, M; Nakamoto, T; Wilber, JF, 1984) |
| " The infant developed apnea, and not having known the above maternal history, was started on caffeine therapy." | 3.67 | Maternal coffee drinking and unusually high concentrations of caffeine in the newborn. ( Khanna, NN; Somani, SM, 1984) |
| "The toxic interaction of caffeine and phenytoin during pregnancy was investigated in mice of the ICR strain on E10 of gestation." | 3.67 | The toxicology of chemical interactions during pregnancy in the mouse: caffeine and phenytoin. ( Kwasigroch, TE; Poche, PD; Skalko, RG, 1984) |
| "Alterations in blood flow to the uterus and its contents during pregnancy have been suggested to account for the teratogenicity and/or embryotoxicity of several agents, including caffeine." | 3.67 | Blood flow changes and conceptal development in pregnant rats in response to caffeine. ( Grafton, TF; Kimmel, CA; Kimmel, GL; Nelson, CJ; White, CG; Young, JF, 1984) |
| "Use of alcohol, caffeine, and nicotine during pregnancy can have serious consequences for the fetus, such as low birth weight, congenital anomalies, or even death." | 3.66 | Alcohol, caffeine, and nicotine as factors in pregnancy. ( Lodge, JR; Weathersbee, PS, 1979) |
| "Caffeine was administered intraperitoneally to CD-1 mice on days 11 and 12 of pregnancy at doses of 80-250 mg/kg." | 3.66 | Caffeine-induced limb malformations: description of malformations and quantitation of placental transfer. ( Scott, WJ, 1983) |
| "Pancreatic function was investigated in neonatal suckling offspring of caffeine-ingesting dams, with or without maternal sucrose supplementation, throughout pregnancy and lactation." | 3.66 | The effect of maternal caffeine ingestion on pancreatic function in the neonatal rat. ( Court, JM; Dunlop, M; Larkins, RG, 1982) |
| " We raise the hypothesis that Cafergot (1 mg ergotamine tartrate and 100 mg caffeine) might represent a vascular disruptive teratogenic agent during pregnancy." | 3.66 | Jejunal atresia associated with Cafergot ingestion during pregnancy. ( Graham, JM; Hoefnagel, D; Marin-Padilla, M, 1983) |
| "The newborn's potential for xanthine toxic reactions from placental transfer of theophylline or caffeine conversion from theophylline was studied in 12 newborns of asthmatic mothers." | 3.66 | Placental theophylline transfer in pregnant asthmatics. ( Labovitz, E; Spector, S, 1982) |
| "Reduced offspring growth was found following introduction of caffeine into the normal diet of rats during pregnancy and lactation." | 3.66 | The effects of maternal carbohydrate (sucrose) supplementation on the growth of offspring of pregnancies with habitual caffeine consumption. ( Court, JM; Dunlop, M; Larkins, RG, 1981) |
| "When caffeine (1,3,7-trimethylxanthine) was introduced into the diet of rats throughout pregnancy and lactation at levels of consumption of 10 mg/kg/day, offspring of successive pregnancies showed growth reductions." | 3.66 | Effects of maternal caffeine ingestion on neonatal growth in rats. ( Court, JM; Dunlop, M, 1981) |
| "1 In Charles River CD1 mice, a single dose of 100 mg kg-1 caffeine injected intraperitoneally on day 14 of pregnancy caused a low incidence of cleft palate in the fetuses." | 3.66 | Acute studies to investigate the mechanism of action of caffeine as a teratogen in mice. ( Elmazar, MM; McElhatton, PR; Sullivan, FM, 1981) |
| " Lipolysis has been estimated by measuring the release of glycerol in isolated adipose tissue cells obtained from women in early prognancy, late pregnancy and 1 - 3 days post partum and from non-pregnant women." | 3.65 | The effect of pregnancy on the control of lipolysis in fat cells isolated from human adipose tissue. ( Elliott, JA, 1975) |
| "Treatment with caffeine has reduced intra-partum mortality and/or improved metabolic indicators in other species following hypoxia." | 3.01 | Maternal caffeine administration to ewes does not affect perinatal lamb survival. ( Doran, GS; Edwards, SH; Friend, MA; Robertson, SM, 2021) |
| "Caffeine or NaCl 0." | 2.90 | Caffeine administered to pregnant sows improves piglet vitality, gas exchange and body weight gain. ( Ballesteros-Rodea, G; Bonilla-Jaime, H; González-Hernández, M; González-Lozano, M; Orozco-Gregorio, H; Roldán-Santiago, P; Sánchez-Salcedo, JA, 2019) |
| "Risk factors for preeclampsia are well established, whereas, the triggers associated with timing of preeclampsia onset are not." | 2.82 | Triggers for Preeclampsia Onset: a Case-Crossover Study. ( Ford, JB; Herbert, RD; Morris, J; Patterson, JA; Roberts, CL; Schemann, K, 2016) |
| "Caffeine is a central nervous system stimulant occurring naturally in some foods and used to treat primary apnoea in premature babies." | 2.58 | Effects of maternal caffeine consumption on the breastfed child: a systematic review. ( Bird, S; Brown, LJ; Chen, YF; McCreedy, A; Shaw-Stewart, J, 2018) |
| " Thus, as an update to this foundational publication, we conducted a systematic review of data on potential adverse effects of caffeine published from 2001 to June 2015." | 2.55 | Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. ( Britt, J; Brorby, GP; Doepker, C; Goldberger, J; Harvey, S; Henderson, R; Lieberman, HR; Myers, E; O'Brien, C; Peck, J; Tenenbein, M; Urban, J; Weaver, C; Welsh, BT; Wikoff, D, 2017) |
| "Eligible studies were identified through a detailed algorithm and hand-search of eligible articles' references; thereafter, summary-effect estimates were calculated by leukemia subtype and dose-response meta-analyses were performed." | 2.52 | Maternal and childhood consumption of coffee, tea and cola beverages in association with childhood leukemia: a meta-analysis. ( Baka, M; Diamantaras, AA; Hatzipantelis, E; Kantzanou, M; Kourti, M; Moschovi, M; Ntouvelis, E; Petridou, ET; Polychronopoulou, S; Sidi, V; Stiakaki, E; Thomopoulos, TP; Tzanoudaki, M, 2015) |
| "Identification of substance abuse and environmental history during preconception period provides an opportunity to assist women in reducing major health risks and identify key determinants of healthy pregnancy." | 2.50 | Preconception care: caffeine, smoking, alcohol, drugs and other environmental chemical/radiation exposure. ( Bhutta, ZA; Dean, SV; Imam, AM; Lassi, ZS, 2014) |
| "Obesity is considered as an independent risk factor for miscarriage, involved in oocyte and embryo quality, but also in endometrial receptivity." | 2.48 | [Nutrition and miscarriages: a literature review]. ( Benammar, A; Cedrin-Durnerin, I; Dupont, C; Faure, C; Hercberg, S; Levy, R; Sermondade, N; Sifer, C, 2012) |
| "Caffeine is a stimulant of central nervous system and therefore is probably the most commonly used psychoactive substance in the world." | 2.48 | [Caffeine--common ingredient in a diet and its influence on human health]. ( Wierzejska, R, 2012) |
| "Adenosine levels increase rapidly with tissue hypoxia and inflammation." | 2.47 | Adverse and protective influences of adenosine on the newborn and embryo: implications for preterm white matter injury and embryo protection. ( Rivkees, SA; Wendler, CC, 2011) |
| "The prevalence of substance abuse in young adults (including women) has increased markedly over the past 20 years." | 2.42 | Anesthetic implications of drug abuse in pregnancy. ( Kuczkowski, KM, 2003) |
| "Caffeine is a widespread natural methylaxanthine which easily crosses the placenta." | 2.41 | [Teratogenic and embryotoxic effects of caffeine: facts and hypotheses]. ( Burdan, F, 2000) |
| "Caffeine is a methylated xanthine that acts as a mild central nervous system stimulant." | 2.41 | Teratogen update: evaluation of the reproductive and developmental risks of caffeine. ( Brent, RL; Christian, MS, 2001) |
| "Nutrition during pregnancy has become an integral component of prenatal care." | 2.39 | Nutrition during pregnancy. ( Luke, B, 1994) |
| "Caffeine is a central nervous system stimulant that has come under increasing scrutiny due to its effects on the health and mental health of those who consume it." | 2.37 | Caffeine: implications of recent research for clinical practice. ( Wells, SJ, 1984) |
| " Therapy for increasing sperm motility includes low dosage androgen and human chorionic gonadotropin." | 2.36 | Sperm motility. ( Amelar, RD; Dubin, L; Schoenfeld, C, 1980) |
| "Subjects included 23 with clinical food allergy at age 3 and/or 6 years, 151 with food sensitization but no clinical food allergy, and 220 controls." | 1.91 | Early-life fecal metabolomics of food allergy. ( Bacharier, LB; Beigelman, A; Brennan, PJ; Bunyavanich, S; Chen, YC; Gold, DR; Jia, X; Kelly, RS; Laranjo, N; Lasky-Su, J; Lee-Sarwar, KA; Litonjua, AA; O'Connor, GT; Weiss, ST; Zeiger, RS, 2023) |
| "Physiologically based pharmacokinetic modeling could be used to predict changes in exposure during pregnancy and possibly inform medicine use in pregnancy in situations in which there is currently limited or no available clinical PK data." | 1.91 | Use of Physiologically Based Pharmacokinetic Modeling for Hepatically Cleared Drugs in Pregnancy: Regulatory Perspective. ( Cole, S; Coppola, P; Kerwash, E, 2023) |
| "Lidocaine was the predominant finding followed by caffeine, and diphenhydramine all of which could result from non-illicit drug exposure, however, there were positives for levamisole, phenacetin, noxiptillin and xylazine none of which are approved in the United States for human therapeutic use." | 1.72 | Qualitative LC-Q-TOF Analysis of Umbilical Cord Tissue via Data-Dependent Acquisition as an Indicator of In Utero Exposure to Toxic Adulterating Substances. ( Browne, T; Cervantes, A; Logan, BK; Nelson, BN; Strathmann, FG, 2022) |
| "Caffeine is a common stressor, and its consumption during pregnancy is widespread." | 1.72 | Differential expression of placental 11β-HSD2 induced by high maternal glucocorticoid exposure mediates sex differences in placental and fetal development. ( Fang, M; Ge, C; Wang, H; Yu, P; Zhang, Y; Zhou, J, 2022) |
| "Epidemiological studies revealed that prenatal caffeine exposure (PCE) is associated with adverse gestational outcomes and susceptibility to chronic diseases in offspring, yet the effects of PCE on glomerulosclerosis susceptibility in adult female offspring and its intergenerational transmission remain to be further investigated." | 1.72 | Prenatal caffeine exposure induced renal developmental toxicity and transgenerational effect in rat offspring. ( Ao, Y; Hu, S; Li, B; Sun, Z; Wang, H; Xia, Z; Xiong, Y; Zhao, X, 2022) |
| "We studied the effect of inducible nitric oxide synthase inhibitor aminoguanidine on learning and spatial memory in rats exposed to long-term administration to caffeine during the prenatal and early postnatal periods." | 1.72 | Effect of Nitric Oxide Synthase Inhibitor on the Learning and Spatial Memory in Rats Subjected to Long-Term Perinatal Administration of Caffeine. ( Alekseeva, EV; Bashkatova, VG; Nazarova, GA; Sudakov, SK, 2022) |
| "Time to miscarriage (days) or censoring was modeled using a multivariate Cox proportional hazards model." | 1.72 | Preconception vitamin D and miscarriage in a prospective cohort study. ( Doss, GL; Jukic, AMZ; Steiner, AZ; Subramanian, A; Weinberg, CR, 2022) |
| "Prochlorperazine injection has been upgraded to a highly recommended level because of the rich clinical experience for this treatment." | 1.72 | 2022 Taiwan Guidelines for Acute Treatment of Migraine. ( Lau, CI; Wang, YF, 2022) |
| "We defined migraineurs as participants who reported a migraine diagnosis or use of a medication to treat migraine." | 1.72 | Pre-pregnancy migraine diagnosis, medication use, and spontaneous abortion: a prospective cohort study. ( Crowe, HM; Hatch, EE; Jick, SS; Mikkelsen, EM; Rothman, KJ; Sørensen, HT; Wesselink, AK; Wise, LA, 2022) |
| "Caffeine intake was weakly associated with increased risk of HDP; the multivariable odds ratio of HDP for the highest versus the lowest quartile was 1." | 1.62 | Hypertensive Disorders of Pregnancy in Relation to Coffee and Tea Consumption: The Japan Environment and Children's Study. ( Ikehara, S; Iso, H; Kakigano, A; Kawanishi, Y; Kimura, T; Sato, T; Tomimatsu, T, 2021) |
| "Caffeine has developmental toxicity." | 1.62 | Prenatal caffeine exposure caused H-type blood vessel-related long bone dysplasia via miR375/CTGF signaling. ( Chen, L; He, H; Liu, L; Luo, H; Shangguan, Y; Wang, H; Wen, Y; Xie, X, 2021) |
| "Caffeine powder was dissolved in distilled water." | 1.62 | Experimental study of pre- and postnatal caffeine exposure and its observable effects on selected neurotransmitters and behavioural attributes at puberty : Caffeine exposure and its observable effects on selected neurotranmitters and behaviour. ( Adefule, KA; Ajibade, TP; Fabiyi, OS; Ogunnaike, PO; Olanrewaju, JA; Olatunji, SY; Owolabi, JO; Oyewumi, S; Shallie, PD, 2021) |
| "Osteoarthritis is associated with intrauterine growth retardation (IUGR) and abnormal glucose metabolism." | 1.56 | Programming changes in GLUT1 mediated the accumulation of AGEs and matrix degradation in the articular cartilage of female adult rats after prenatal caffeine exposure. ( Hui, H; Hui, W; Liang, L; Liao-Bin, C; Lin-Long, W; Qing-Xian, L; Yi-Zhong, W, 2020) |
| " Further research into caffeine dosage and timing postpartum is required to establish its efficacy." | 1.56 | Caffeine supplementation at birth, but not 8 to 12 h post-birth, increased 24 h pre-weaning mortality in piglets. ( Hebart, ML; Kind, K; Nowland, TL; van Wettere, WHEJ, 2020) |
| "In the present study, a rat model of intrauterine growth retardation (IUGR) was established by PCE, and offspring were sacrificed." | 1.51 | Glucocorticoid-activation system mediated glucocorticoid-insulin-like growth factor 1 (GC-IGF1) axis programming alteration of adrenal dysfunction induced by prenatal caffeine exposure. ( He, Z; Huang, H; Magdalou, J; Wang, H; Yuan, C; Zhang, J; Zhu, C, 2019) |
| "Caffeine exposure was associated to SGA (OR = 1." | 1.51 | Caffeine exposure during pregnancy, small for gestational age birth and neonatal outcome - results from the Norwegian Mother and Child Cohort Study. ( Bellocco, R; Brantsæter, AL; Elfvin, A; Jacobsson, B; Meltzer, HM; Modzelewska, D; Sengpiel, V, 2019) |
| "This study aimed to verify the toxic effects of prenatal caffeine exposure (PCE) on the podocyte development in male offspring, and to explore the underlying intrauterine programming mechanisms." | 1.51 | Decreased H3K9ac level of KLF4 mediates podocyte developmental toxicity induced by prenatal caffeine exposure in male offspring rats. ( Ao, Y; Chen, H; Cheng, H; He, H; Li, B; Wang, H; Zhao, X; Zhu, Y, 2019) |
| "Caffeine was fed daily in troughs in each paddock at a rate of 1." | 1.48 | Caffeine supplementation of ewes during lambing may increase lamb survival. ( Doran, GS; Edwards, S; Friend, MA; Robertson, SM, 2018) |
| "Physiologically based pharmacokinetic modeling is considered a valuable tool for predicting pharmacokinetic changes in pregnancy to subsequently guide in-vivo pharmacokinetic trials in pregnant women." | 1.48 | A Physiologically Based Pharmacokinetic Model for Pregnant Women to Predict the Pharmacokinetics of Drugs Metabolized Via Several Enzymatic Pathways. ( Coboeken, K; Dallmann, A; Eissing, T; Hempel, G; Ince, I, 2018) |
| "Febrile seizures (FS) is one of the most common convulsive disorders in infants and young children that only occurs during the first years of life in humans, when the cerebellum is still developing." | 1.48 | Cerebellar oxidative stress and fine motor impairment in adolescent rats exposed to hyperthermia-induced seizures is prevented by maternal caffeine intake during gestation and lactation. ( Crespo, M; León-Navarro, DA; Martín, M, 2018) |
| "Caffeine is a respiratory stimulant used during removal of infants from ventilation but has shown surprising long-term benefits, leading to consideration as a therapy for HI of prematurity." | 1.48 | Behavioral and neuroanatomical outcomes in a rat model of preterm hypoxic-ischemic brain Injury: Effects of caffeine and hypothermia. ( Fitch, RH; Potter, M; Rosenkrantz, T, 2018) |
| " Higher blood levels of caffeine within the range considered therapeutic and safe for human infants correlated with increased neuroapoptosis." | 1.48 | Caffeine Augments Anesthesia Neurotoxicity in the Fetal Macaque Brain. ( Brambrink, AM; Dissen, GA; Ikonomidou, C; Johnson, SA; Manzella, FM; Martin, LD; Masuoka, KL; Noguchi, KK; Olney, JW; Schenning, KJ; Williams, SL, 2018) |
| "Caffeine intake was derived from coffee, tea, soft drinks, and cocoa-containing foods and beverages." | 1.48 | Associations of maternal caffeine intake with birth outcomes: results from the Lifeways Cross Generation Cohort Study. ( Chen, LW; Fitzgerald, R; Kelleher, CC; Mehegan, J; Murrin, CM; Phillips, CM, 2018) |
| " We addressed whether caffeine doses previously determined not to be associated with adverse effects by Health Canada (400 mg/day for healthy adults, 300 mg/day for pregnant women, 2." | 1.48 | Key Findings and Implications of a Recent Systematic Review of the Potential Adverse Effects of Caffeine Consumption in Healthy Adults, Pregnant Women, Adolescents, and Children. ( Doepker, C; Franke, K; Goldberger, JJ; Lieberman, HR; Myers, E; O'Brien, C; Peck, J; Tenenbein, M; Weaver, C; Wikoff, D, 2018) |
| "The pregnancy was complicated by maternal gestational diabetes mellitus and pre-eclampsia." | 1.46 | A Newborn Infant With Oxygen Desaturation During Sleep. ( Daftary, A; Deschamp, A, 2017) |
| "Caffeine is a non-selective adenosine antagonist; therefore, it can modulate metabolic pathways in these tissues." | 1.46 | The perinatal effects of maternal caffeine intake on fetal and neonatal brain levels of testosterone, estradiol, and dihydrotestosterone in rats. ( Bayrak, S; Erdem, A; Erdogan, G; Ergun, EL; Karaismailoglu, S; Tuncer, M, 2017) |
| "Newborns with acute chorioamnionitis benefited from early caffeine therapy." | 1.43 | Effect of early caffeine on neurodevelopmental outcome of very low-birth weight newborns. ( Chouthai, NS; Gupta, D; Gupte, AS; Ma, MM; Ravichandran, S, 2016) |
| "19 children had OSAS (9." | 1.43 | Perinatal Risk Factors Associated with the Obstructive Sleep Apnea Syndrome in School-Aged Children Born Preterm. ( Cielo, CM; Doyle, LW; Marcus, CL; Nixon, GM; Shults, J; Tapia, IE; Traylor, J, 2016) |
| "Furthermore, caffeine treatment during pregnancy and lactation causes long-term behavioral changes in the mice offspring that manifest later in life." | 1.43 | Behavioral profile assessment in offspring of Swiss mice treated during pregnancy and lactation with caffeine. ( Côrtes, Wda S; da Conceição, RR; da Rocha, FF; da Silva-Almeida, C; da Silveira, AL; de Azevedo Cruz Seara, F; Laureano-Melo, R; Marinho, BG; Reis, LC, 2016) |
| " This association demonstrated a dose-response relationship: OR=1." | 1.42 | Maternal caffeine intake during pregnancy and risk of obesity in offspring: a prospective cohort study. ( Ferber, JR; Li, DK; Odouli, R, 2015) |
| "Caffeine treatment increased both RR and NG latency times." | 1.42 | Maternal caffeine exposure alters neuromotor development and hippocampus acetylcholinesterase activity in rat offspring. ( Bogo, MR; Bonan, CD; Capiotti, KM; Caumo, W; Da Silva, RS; De Oliveira, C; Kist, LW; Medeiros, LF; Scarabelot, VL; Souza, A; Souza, AC; Torres, IL, 2015) |
| "The outcome of interest was severe preeclampsia, and exposures were serum paraxanthine (1,7-dimethylxanthine), measured through high-performance liquid chromatography, and CYP1A2 activity, assessed by paraxanthine/caffeine ratios." | 1.42 | Second-Trimester Maternal Serum Paraxanthine, CYP1A2 Activity, and the Risk of Severe Preeclampsia. ( Baker, AM; Eichelberger, KY; Haeri, S; Strauss, RA; Stuebe, AM; Woodham, PC, 2015) |
| "Caffeine, which is an ATM (ataxia telangiectasia mutated) and ATR (ataxia telangiectasia and Rad3-related protein) kinase inhibitor, and KU55933, which is an ATM kinase inhibitor, were equally effective in rescuing the etoposide-induced cell-cycle blocks." | 1.42 | Effect of ATM and HDAC Inhibition on Etoposide-Induced DNA Damage in Porcine Early Preimplantation Embryos. ( Cui, XS; Kim, NH; Kwon, J; Lee, IW; Lin, Z; Luo, Y; Wang, H, 2015) |
| "Caffeine was investigated for its possible fetal programming effects on reproductive function of male offspring." | 1.42 | Effects of Oral Maternal Administration of Caffeine on Reproductive Functions of Male Offspring of Wistar Rats. ( Akindele, OO; Ogunwole, E; Oluwole, OF; Raji, Y; Salami, SA, 2015) |
| "Severe NAFLD appeared with higher Kleiner scores." | 1.40 | Intrauterine metabolic programming alteration increased susceptibility to non-alcoholic adult fatty liver disease in prenatal caffeine-exposed rat offspring. ( Chen, L; Huang, H; Liu, Y; Liu, Z; Ping, J; Shen, L; Wang, H; Wang, L; Wu, Y; Zhang, L, 2014) |
| "This caffeine treatment results in serum levels equivalent to the consumption of 2-4 cups of coffee in humans." | 1.40 | Embryonic caffeine exposure acts via A1 adenosine receptors to alter adult cardiac function and DNA methylation in mice. ( Buscariollo, DL; Fang, X; Greenwood, V; Rivkees, SA; Wendler, CC; Xue, H, 2014) |
| "Caffeine has been an integral component of our diet and medicines for centuries." | 1.40 | Excess caffeine exposure impairs eye development during chick embryogenesis. ( Cheng, X; Chuai, M; Kurihara, H; Lee, KK; Ma, ZL; Wang, G; Yang, X, 2014) |
| "Caffeine is widely used to treat apnea of prematurity, but the standard dosing regimen is not always sufficient to prevent apnea." | 1.40 | Impact of daily high-dose caffeine exposure on developing white matter of the immature ovine brain. ( Atik, A; Cheong, J; De Matteo, R; Harding, R; Rees, S; Tolcos, M, 2014) |
| "This study aimed to evaluate the role of caffeine chronic administration during gestation of C57BL/6 mice on cardiac remodeling and the expression of components of the renin-angiotensin system (RAS) in male offspring as adults." | 1.39 | Maternal caffeine administration leads to adverse effects on adult mice offspring. ( Aguila, MB; Faria, TS; Mandarim-de-Lacerda, CA; Serapiao-Moraes, DF; Souza-Mello, V, 2013) |
| "Caffeine intake was consistently associated with decreased BW and increased odds of SGA." | 1.39 | Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results from a large prospective observational cohort study. ( Alexander, J; Bacelis, J; Brantsaeter, AL; Elind, E; Grove, J; Haugen, M; Jacobsson, B; Meltzer, HM; Myhre, R; Nilsson, S; Sengpiel, V, 2013) |
| "Caffeine pretreatment induced higher mitogen-activated protein kinases (MAPK1 and MAPK3) phosphorylation and maturation-promoting factor activity at 12 hours and activated MAPK1 and maturation-promoting factor at 48 hours after culture in cumulus-oocyte complexes (COCs) compared with the control group (P < 0." | 1.39 | Influence of caffeine pretreatment on biphasic in vitro maturation of dog oocytes. ( Fouladi-Nashta, AA; Ghafari, F; Salavati, M; Zhang, T, 2013) |
| "Clomipramine was injected at 40 mg/kg and 80 mg/kg to the second and third groups, respectively." | 1.39 | The role of clomipramine in potentiating the teratogenic effects of caffeine in pregnant rats: a histopathological study. ( Bakhtiarian, A; Giorgi, M; Nabavi, SM; Nikoui, V; Ostadhadi, S; Takzare, N, 2013) |
| "Caffeine is a definite factor of intrauterine growth retardation (IUGR)." | 1.38 | A hypothalamic-pituitary-adrenal axis-associated neuroendocrine metabolic programmed alteration in offspring rats of IUGR induced by prenatal caffeine ingestion. ( Chen, LB; Lei, YY; Liu, F; Liu, J; Liu, YS; Magdalou, J; Ping, J; Qin, J; Shen, L; Wang, H; Wu, Y; Xu, D; Zhang, C, 2012) |
| "Caffeine also has a potentially negative influence on bones." | 1.37 | The influence of caffeine on the biomechanical properties of bone tissue during pregnancy in a population of rats. ( Chadaj-Polberg, E; Olchowik, G; Polberg, M; Tomaszewska, M; Tomaszewski, M, 2011) |
| "Caffeine consumption has been equivocally associated with miscarriage, despite an absence of prospective longitudinal measurement of caffeine intake during sensitive windows of human development." | 1.36 | Caffeine consumption and miscarriage: a prospective cohort study. ( Buck Louis, GM; Lum, KJ; Pollack, AZ; Sundaram, R, 2010) |
| "There were 84 cases of undescended testes at birth persisting to at least age 2 years among 7,574 liveborn sons whose mothers were interviewed in early pregnancy." | 1.35 | Maternal smoking, alcohol consumption, and caffeine consumption during pregnancy in relation to a son's risk of persistent cryptorchidism: a prospective study in the Child Health and Development Studies cohort, 1959-1967. ( Christianson, RE; Cohen, RD; Cohn, BA; Mongraw-Chaffin, ML, 2008) |
| "Caffeine-treated NTs induced premature chromosome condensation at a high rate (P<0." | 1.35 | Control of nuclear remodelling and subsequent in vitro development and methylation status of porcine nuclear transfer embryos. ( Cheong, HT; Kwon, DJ; Park, CK; Yang, BK, 2008) |
| "Both nicotine and cocaine were always retrieved together with their main metabolite." | 1.35 | Nails of newborns in monitoring drug exposure during pregnancy. ( Bertol, E; Mari, F; Politi, L, 2008) |
| " Induction of Cytochrome P450 (Cyp)1b1 in maternal liver may reduce bioavailability of DBP to the fetus as a mechanism of chemoprevention." | 1.35 | Chemoprevention of dibenzo[a,l]pyrene transplacental carcinogenesis in mice born to mothers administered green tea: primary role of caffeine. ( Castro, DJ; Dashwood, RH; Fischer, KA; Giovanini, JN; Löhr, CV; Orner, GA; Pereira, CB; Williams, DE; Yu, Z, 2008) |
| "Caffeine is a widely used psychostimulant freely crossing the placental barrier." | 1.35 | Maternal caffeine ingestion during gestation and lactation influences respiratory adaptation to acute alveolar hypoxia in newborn rats and adenosine A2A and GABA A receptor mRNA transcription. ( Guénin, S; Larnicol, N; Perrin, Y; Picard, N, 2008) |
| "Caffeine was dissolved in normal saline, so it was used as a control." | 1.35 | Embryonic caffeine exposure induces adverse effects in adulthood. ( Busovsky-McNeal, M; Ghatpande, S; Kalinowski, A; Rivkees, SA; Russell, KS; Wendler, CC, 2009) |
| "The caffeine intake was quantified starting from the consumption of: powdered chocolate, chocolate bar or chocolate, soft drink, coffee and mate tea." | 1.35 | [Caffeine consumption by pregnant women selected from a Health Care Center in the municipality of Rio de Janeiro, Brazil]. ( Araujo, DM; Kac, G; Lacerda, EM; Pacheco, AH, 2008) |
| " The direction of dosing adjustments during pregnancy will depend on the drug and the enzyme that is responsible for its metabolism." | 1.33 | Temporal changes in drug metabolism (CYP1A2, CYP2D6 and CYP3A Activity) during pregnancy. ( Caritis, SN; Glover, DD; Tracy, TS; Venkataramanan, R, 2005) |
| "Reverse causation due to unrecognized fetal demise may explain the association between coffee intake and risk of fetal death prior to 20 completed weeks' gestation but not the association with fetal loss following 20 completed weeks' gestation." | 1.33 | Coffee and fetal death: a cohort study with prospective data. ( Bech, BH; Henriksen, TB; Nohr, EA; Olsen, J; Vaeth, M, 2005) |
| "Caffeine consumption was estimated from dietary records collected at the same gestational ages." | 1.33 | In pregnant women who smoke, caffeine consumption is associated with an increased level of homocysteine. ( Carlsen, SM; Jacobsen, G; Romundstad, P; Vatten, L, 2005) |
| "The brains of fetal alcohol syndrome patients exhibit impaired neuronal migration, but little is known about the mechanisms underlying this abnormality." | 1.33 | Reversal of neuronal migration in a mouse model of fetal alcohol syndrome by controlling second-messenger signalings. ( Komuro, H; Kumada, T; Lakshmana, MK, 2006) |
| "The risks of repeated miscarriage were increased for women aged > or = 35 years (adjusted OR 2." | 1.33 | Risks of repeated miscarriage. ( Cnattingius, S; George, L; Granath, F; Johansson, AL; Olander, B, 2006) |
| "We studied the morphological changes of the dendritic length of the pyramidal neurons of the prefrontal cortex (PFC) induced by the effect of chronic administration of caffeine in the neonatal rat." | 1.33 | Neonatal caffeine administration causes a permanent increase in the dendritic length of prefrontal cortical neurons of rats. ( Carretero, R; Flores, G; Juárez-Méndez, S; Martínez-Tellez, R; Silva-Gómez, AB, 2006) |
| "In caffeine group, an increase in the baseline Rf in presence of the pons and no change in medullary-spinal cord preparations have been observed." | 1.32 | Involvement of adenosinergic A1 systems in the occurrence of respiratory perturbations encountered in newborns following an in utero caffeine exposure. a study on brainstem-spinal cord preparations isolated from newborn rats. ( Bodineau, L; Frugière, A; Gaytan, S; Gros, F; Saadani-Makki, F, 2004) |
| "Caffeine did not enhance fertility or prolificacy, regardless of its ability to increase sperm motility." | 1.31 | Effects of added caffeine on results following artificial insemination with fresh and refrigerated rabbit semen. ( Alvariño, JM; López, FJ, 2000) |
| "Caffeine was administered in Tween 80 solution, once daily, in oral bolus, during the whole second trimester, in three doses: C1--0." | 1.31 | The effects of short-time caffeine administration on skeleton development in Wistar rats. ( Burdan, F; Maciejewski, R; Madej, B; Radzikowska, E; Wójtowicz, Z, 2000) |
| "Caffeine treatment had no significant effect on adenosine A1 receptors or on A1 receptor mRNA." | 1.31 | Maternal caffeine intake has minor effects on adenosine receptor ontogeny in the rat brain. ( Adén, U; Fredholm, BB; Herlenius, E; Tang, LQ, 2000) |
| "Caffeine is an alkaloid widely consumed by humans." | 1.31 | Caffeine decreases the occurrence of cadmium-induced forelimb ectrodactyly in C57BL/6J mice. ( Beck, SL; Lutz, J, 2000) |
| "Smoking during pregnancy is a significant public health issue, and studies of the effectiveness of interventions to reduce maternal smoking require accurate measurement of smoking status." | 1.31 | A simple high-pressure liquid chromatography cotinine assay: validation of smoking status in pregnant women. ( Brennecke, S; Greaves, R; Janus, E; Trotter, L, 2001) |
| "Caffeine was used as a metabolic probe." | 1.31 | The effect of pregnancy on cytochrome P4501A2, xanthine oxidase, and N-acetyltransferase activities in humans. ( Ishii, Y; Kodama, Y; Kotegawa, T; Kuranari, M; Matsuki, S; Miyakawa, I; Nakano, S; Tanaka, Y; Tsutsumi, K, 2001) |
| "Caffeine was a risk factor for spontaneous abortion among women with high, but not low, CYP1A2 activity (OR 2." | 1.31 | Caffeine metabolism and the risk of spontaneous abortion of normal karyotype fetuses. ( Annerén, G; Blot, WJ; Cnattingius, S; Ekbom, A; Granath, F; Lundgren, S; McLaughlin, JK; Nordmark, A; Rane, A; Signorello, LB, 2001) |
| "Caffeine intake was not significantly associated with other outcomes." | 1.31 | A prospective study of the effects of female and male caffeine consumption on the reproductive endpoints of IVF and gamete intra-Fallopian transfer. ( Bleha, J; Klonoff-Cohen, H; Lam-Kruglick, P, 2002) |
| "No nicotine was present in the samples because of its rapid metabolism into cotinine." | 1.30 | Determination of nicotine, cotinine and caffeine in meconium using high-performance liquid chromatography. ( Baranowska, I; Baranowski, J; Pochopień, G, 1998) |
| " Among men no dose-response association was found after control for confounders including women's alcohol intake." | 1.30 | Does moderate alcohol consumption affect fertility? Follow up study among couples planning first pregnancy. ( Bonde, JP; Ernst, E; Giwercman, A; Henriksen, TB; Hjollund, NH; Jensen, TK; Kolstad, H; Olsen, J; Scheike, T; Skakkebaek, NE, 1998) |
| "Amiloride in H2O was called 'bitter', and the incidence of bitter descriptions was significantly associated with the presence of amiloride." | 1.30 | Effects of amiloride on gustatory quality descriptions and temporal patterns produced by NaCl. ( Darlington, RB; Halpern, BP, 1998) |
| " However, postimplantation embryo development assessed on Day 12 of gestation revealed that caffeine exposure of 15 and 30 mg kg(-1) significantly reduced, at both dosage levels, somite number and the extent of neural tube closure." | 1.30 | Maternal caffeine consumption during pregnancy does not affect preimplantation development but delays early postimplantation growth in rat embryos. ( Jacombs, A; Loupis, A; Pollard, I; Ryan, J, 1999) |
| " Prenatal caffeine at the dosage we have used in combination with malnutrition may produce lasting metabolic alterations in the nervous system related to the emergence of suckling behavior and general motor activity." | 1.29 | Combined effects of caffeine and malnutrition during pregnancy on suckling behavior in newborn rats. ( Joseph, F; Nakamoto, T; Narayanan, CH; Saito, T; Yoshino, S, 1994) |
| "05) higher CA-derived radioactivity was seen in maternal brain, carcass and heart as well as placenta and fetal heads and bodies 6 hr after dosing with CA in DMSO compared to CA in DW." | 1.29 | Alteration in the tissue retention of [14C]-caffeine in pregnant mice by dimethylsulfoxide. ( Gross, SM; Reddy, CS; Reddy, RV, 1993) |
| "When caffeine was present, a third factor had to be taken into consideration: direct inhibition of repair by caffeine." | 1.29 | Relation between rate of cell proliferation and formation of micronuclei after combined treatment with X-rays and caffeine. ( Kasper, C; Müller, WU; Streffer, C, 1993) |
| " Following dosing with caffeine no change in the distribution of staining for hsp 90, 70 and 25 was found." | 1.29 | Immunohistochemical localisation of the 90, 70 and 25 kDa heat shock proteins in control and caffeine treated rat embryos. ( Pollard, I; Wilkinson, JM, 1993) |
| "A caffeine tablet was implanted subcutaneously in the experimental group and a placebo tablet in the control group." | 1.29 | The effect of prenatal caffeine exposure on the enamel surface of the first molars of newborn rats. ( Falster, AU; Hashimoto, K; Joseph, F; Nakamoto, T; Simmons, WB; Yoshino, S, 1993) |
| "In the past 20 years, sexually transmitted diseases (STDs), including AIDS, and the physical, psychological, and economic difficulties associated with unwanted pregnancy have increased steadily among American adolescents." | 1.29 | Lifestyle and risk of premature sexual activity in a high school population of Seventh-Day Adventists: Valuegenesis 1989. ( Rossignol, AM; Weinbender, ML, 1996) |
| " Furthermore, among women with a high intake of caffeine a dose-response relationship was found; women smoking one to five cigarettes per day had no increased risk of preterm birth compared with nonsmokers with the same intake of caffeine, women smoking six to ten cigarettes per day had almost three times higher risk of preterm birth, and women smoking more than 10 cigarettes per day had almost five times higher risk of preterm birth compared with nonsmokers with the same intake of caffeine." | 1.29 | Smoking during pregnancy and preterm birth. ( Hedegaard, M; Henriksen, TB; Secher, NJ; Wisborg, K, 1996) |
| "Experiments examining seizure sensitivity were conducted on adult male offspring exposed to diazepam at 1." | 1.28 | Gestational exposure to diazepam increases sensitivity to convulsants that act at the GABA/benzodiazepine receptor complex. ( Bitran, D; Kellogg, CK; Primus, RJ, 1991) |
| "Caffeine has been associated with a number of reproductive and developmental effects in animals and humans." | 1.28 | Somatic development of the infant monkey following in utero exposure to caffeine. ( Gilbert, SG; Rice, DC, 1991) |
| "We looked at risk of early pregnancy loss among 171 women who conceived while participating in study." | 1.28 | Risk factors for early pregnancy loss. ( Baird, DD; Weinberg, CR; Wilcox, AJ, 1990) |
| "Caffeine (100 mg/kg) was administered intravenously to dams on day 21 of gestation." | 1.28 | Maternal-fetal electrocardiographic effects and pharmacokinetics after an acute i.v. administration of caffeine to the pregnant rat. ( Barletta, M; Carson, S; Leal, M, 1990) |
| "The caffeine supplement was 20 mg/kg body-weight." | 1.28 | Prenatal effects of maternal caffeine intake and dietary high protein on mandibular development in fetal rats. ( Driscoll, PG; Joseph, F; Nakamoto, T, 1990) |
| "The caffeine inhibition was not enhanced when calcium channels were opened by a conditioning depolarizing pulse sequence or when the number of inactivated calcium channels was increased at depolarized holding potentials." | 1.28 | Caffeine-induced inhibition of calcium channel current in cultured smooth cells from pregnant rat myometrium. ( Dacquet, C; Martin, C; Mironneau, C; Mironneau, J, 1989) |
| "3H-thymidine was effective in inducing SCEs only at 250 Bq/ml, whereas UV light was effective at both fluences." | 1.27 | Induction of sister chromatid exchange in preimplantation mouse embryos in vitro by 3H-thymidine or ultraviolet light in combination with caffeine. ( Müller, WU; Spindle, A, 1986) |
| "Valproic acid, which is an isomer of 2-EXHA, also produced similar defects, and was approximately twice as potent as 2-EHXA." | 1.27 | Teratogenicity of di(2-ethylhexyl) phthalate, 2-ethylhexanol, 2-ethylhexanoic acid, and valproic acid, and potentiation by caffeine. ( Randall, JL; Ritter, EJ; Ritter, JM; Scott, WJ, 1987) |
| "Caffeine has previously been demonstrated to be teratogenic in mice, causing primarily limb reduction defects and cleft palate." | 1.27 | Interactions between caffeine and adenosine agonists in producing embryo resorptions and malformations in mice. ( Clark, RL; Cusick, WA; Eschbach, K; Heyse, JF, 1987) |
| "Caffeine, 175 mg/kg, was given ip on Days 11 and 12 of gestation." | 1.27 | Alteration of effective exposure of dam and embryo to caffeine and its metabolites by treatment of mice with beta-naphthoflavone. ( O'Flaherty, EJ; Scott, WJ; Shukla, R; York, RG, 1987) |
| "Pregnant mice were exposed before implantation to caffeine and ethanol to determine the dose-response relation for embryolethality during the preimplantation period." | 1.27 | Studies on the embryotoxic risk of exposure to caffeine and ethanol during the preimplantation period in the mouse. ( Granata, I; Krüger, C; Spielmann, H; Tenschert, B; Vogel, R, 1987) |
| " Treatment was continued through 3 wk of serial mating; mating and dosing were terminated concurrently, after which the sires were autopsied and their testes weighed." | 1.27 | Reproduction study of caffeine administration to male Osborne-Mendel rats. ( Black, TN; Collins, TF; Gray, GC; Green, S; O'Donnell, M; Welsh, JJ; West, WL; Whitby, KE, 1986) |
| "Caffeine at high doses is a known rodent teratogen and induces limb malformations along with cleft palate in various strains of rats and mice." | 1.27 | Prevention of caffeine-induced limb malformations by maternal adrenalectomy. ( Moriguchi, M; Scott, WJ, 1986) |
| " A dosage of eighty mg/kg/d was more effective than 20 mg/kg/d beta-NF in decreasing malformations, suggesting that stimulation of metabolism and caffeine-induced teratogenicity are inversely related." | 1.27 | Reduction of caffeine teratogenicity in mice by inducing maternal drug metabolism with beta-naphthoflavone. ( Randall, JL; Scott, WJ; York, RG, 1985) |
| "When caffeine was added to cultures with BP (1 microM, a concentration that was not embryotoxic and did not induce SCEs), both embryotoxic effects and SCE frequency were increased." | 1.27 | Developmental and cytogenetic effects of caffeine on mouse blastocysts, alone or in combination with benzo(a)pyrene. ( Spindle, A; Wu, K, 1985) |
| "When caffeine was given immediately after carcinogen treatment on Day 10, urethan- and N-ethyl-N-nitrosourea-induced malformations were significantly suppressed by caffeine posttreatment, while N-hydroxyurethan- and N-methyl-N-nitrosourea-induced malformations were not suppressed by caffeine." | 1.27 | Antiteratogenic effects of tumor inhibitors, caffeine, antipain, and retinoic acid in mice. ( Enomoto, T; Hata, S; Kanzaki, T; Kimura, S; Kusafuka, T; Miyamoto, S; Nomura, T; Shibata, K; Sobue, K; Tanaka, H, 1983) |
| "Aminophylline treatment of pregnant rabbits for 2 days, beginning at 25." | 1.27 | Effect of aminophylline and caffeine on total and surfactant phospholipid in fetal rabbit lung. ( Corbet, A; Cregan, J; Frink, J; Landers, S; Rudolph, AJ, 1984) |
| "Caffeine was detected by 15 minutes in saliva and milk; peak levels in milk (2." | 1.27 | Disposition of dietary caffeine in milk, saliva, and plasma of lactating women. ( Berlin, CM; Daniel, CH; Denson, HM; Ward, RM, 1984) |
| "Caffeine was undetectable in all the maternal and fetal samples obtained 48 hours after the infusion." | 1.27 | Pharmacokinetic and hemodynamic effects of caffeine in the pregnant sheep. ( Ayromlooi, J; Errick, JK; Wilson, SJ, 1983) |
| "In 6-day pregnant New Zealand White rabbits dosed intravenously with 3H-nicotine, the 3H-activity in the uterine fluid was approximately 5 to 11 times greater than that in the plasma at the corresponding times; 3H-nicotine itself accounted for most of this radioactivity." | 1.26 | Accumulation of nicotine in the uterine fluid of the six-day pregnant rabbit. ( Dames, NM; Fabro, S; McLachlan, JA; Sieber, SM, 1976) |
| "When indomethacin was added to the myometrial extracts, the activity of the high Km phosphodiesterase was competitively inhibited, with an average Ki of 200 muM; the low Km enzyme was noncompetitively inhibited with an average Ki of 110 muM." | 1.26 | Effect of Indomethacin on cyclic AMP phosphodiesterase activity in myometrium from pregnant rhesus monkeys. ( Beatty, CH; Bocek, RM; Novy, MJ; Young, MK, 1976) |
| "In a previous experiment, fetopathic effects of caffeine were significantly reduced by pretreatment with propranolol at dosage levels of 2." | 1.26 | Mitigation of caffeine-induced fetopathy in mice by pretreatment with beta-adrenergic blocking agents. ( Fujii, T, 1976) |
| " When [1-methyl-14C]caffeine was administered at a dosage of 80 mg per kg per day by ad libitum sipping on days 12 to 15 of gestation, the amounts of radioactivity in blood were variable; the highest level on day 12 was 0." | 1.26 | Blood levels of caffeine and results of fetal examination after oral administration of caffeine to pregnant rats. ( Bragg, LE; Collins, TF; Ikeda, GJ; McGinnis, ML; Sapienza, PP; Walsh, JJ, 1982) |
| "Caffeine has a multitude of pharmacologic actions and its effects must be determined on the fetus and newborn in the immediate future for suggestive evidence links caffeine with such fetal and newborn pathology as pre- and postmaturity and intrauterine growth retardation." | 1.26 | Caffeine ingestion during pregnancy: in utero exposure and possible effects. ( Soyka, LF, 1981) |
| "Caffeine was administered in the diet to rats throughout gestation." | 1.26 | Brain catecholamines and sleep states in offspring of caffeine-treated rats. ( Enslen, M; Milon, H; Würzner, HP, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 336 (31.91) | 18.7374 |
| 1990's | 178 (16.90) | 18.2507 |
| 2000's | 187 (17.76) | 29.6817 |
| 2010's | 250 (23.74) | 24.3611 |
| 2020's | 102 (9.69) | 2.80 |
| Authors | Studies |
|---|---|
| Owolabi, JO | 1 |
| Adefule, KA | 1 |
| Shallie, PD | 1 |
| Fabiyi, OS | 1 |
| Olatunji, SY | 1 |
| Olanrewaju, JA | 1 |
| Ajibade, TP | 1 |
| Oyewumi, S | 1 |
| Ogunnaike, PO | 1 |
| He, Z | 9 |
| Zhang, J | 5 |
| Chen, G | 3 |
| Cao, J | 1 |
| Chen, Y | 2 |
| Ai, C | 2 |
| Wang, H | 49 |
| Nelson, BN | 1 |
| Strathmann, FG | 1 |
| Browne, T | 1 |
| Cervantes, A | 1 |
| Logan, BK | 1 |
| Polinski, KJ | 1 |
| Purdue-Smithe, A | 2 |
| Robinson, SL | 1 |
| Zhao, SK | 2 |
| Schliep, KC | 3 |
| Silver, RM | 4 |
| Guan, W | 1 |
| Schisterman, EF | 5 |
| Mumford, SL | 5 |
| Yeung, EH | 1 |
| Easey, KE | 1 |
| Sharp, GC | 1 |
| Hinkle, SN | 6 |
| Gleason, JL | 3 |
| Yisahak, SF | 1 |
| Sundaram, R | 5 |
| Grewal, J | 1 |
| Grantz, KL | 4 |
| Zhang, C | 7 |
| Haan, E | 2 |
| Sallis, HM | 2 |
| Zuccolo, L | 2 |
| Labrecque, J | 1 |
| Ystrom, E | 1 |
| Reichborn-Kjennerud, T | 2 |
| Andreassen, O | 1 |
| Havdahl, A | 2 |
| Munafò, MR | 4 |
| Purdue-Smithe, AC | 1 |
| Kim, K | 3 |
| DeVilbiss, EA | 1 |
| Ye, A | 2 |
| Perkins, NJ | 2 |
| Sjaarda, LA | 3 |
| McPherson, C | 1 |
| Lean, RE | 1 |
| Cyr, PEP | 1 |
| Inder, TE | 1 |
| Rogers, CE | 1 |
| Smyser, CD | 1 |
| Zhang, WZ | 1 |
| Sun, NN | 1 |
| Hu, Y | 1 |
| Cao, Y | 1 |
| Amber, S | 1 |
| Yu, P | 1 |
| Zhou, J | 2 |
| Ge, C | 1 |
| Fang, M | 1 |
| Zhang, Y | 5 |
| Westmoreland, KE | 1 |
| Schellhas, L | 1 |
| Taylor, G | 1 |
| Tung, KTS | 1 |
| Wong, RS | 1 |
| Cheung, CKM | 1 |
| Ko, JKY | 1 |
| Chan, BNK | 1 |
| Lee, A | 1 |
| So, HK | 1 |
| Wong, WHS | 1 |
| Leung, WC | 1 |
| Ip, P | 1 |
| Zhao, X | 2 |
| Li, B | 5 |
| Xiong, Y | 1 |
| Xia, Z | 1 |
| Hu, S | 5 |
| Sun, Z | 2 |
| Ao, Y | 3 |
| Saimaiti, A | 1 |
| Zhou, DD | 1 |
| Li, J | 7 |
| Xiong, RG | 1 |
| Gan, RY | 1 |
| Huang, SY | 1 |
| Shang, A | 1 |
| Zhao, CN | 1 |
| Li, HY | 1 |
| Li, HB | 1 |
| Shi, H | 2 |
| Gao, H | 1 |
| He, H | 3 |
| Wu, Z | 2 |
| Magdaloud, J | 1 |
| Chen, L | 23 |
| Bashkatova, VG | 2 |
| Alekseeva, EV | 2 |
| Nazarova, GA | 2 |
| Sudakov, SK | 2 |
| Nishihara, S | 1 |
| Kobayashi, S | 3 |
| Ikeda-Araki, A | 1 |
| Miyashita, C | 2 |
| Itoh, S | 2 |
| Yamazaki, K | 2 |
| Bamai, YA | 1 |
| Tamura, N | 1 |
| Masuda, H | 1 |
| Itoh, M | 1 |
| Saijo, Y | 3 |
| Ito, Y | 1 |
| Kishi, R | 4 |
| Subramanian, A | 1 |
| Steiner, AZ | 1 |
| Weinberg, CR | 3 |
| Doss, GL | 1 |
| Jukic, AMZ | 1 |
| Magenis, ML | 1 |
| Damiani, AP | 1 |
| Franca, IB | 1 |
| de Marcos, PS | 1 |
| Effting, PS | 1 |
| Muller, AP | 1 |
| de Bem Silveira, G | 1 |
| Borges Correa, MEA | 1 |
| Medeiros, EB | 1 |
| Silveira, PCL | 1 |
| Budni, J | 1 |
| Boeck, CR | 1 |
| de Andrade, VM | 1 |
| Surma, S | 1 |
| Witek, A | 1 |
| Lu, M | 2 |
| He, X | 4 |
| Jiao, Z | 1 |
| Hu, Z | 1 |
| Guo, Z | 2 |
| Dai, S | 1 |
| Xu, D | 16 |
| Laue, HE | 1 |
| Shen, Y | 1 |
| Bloomquist, TR | 1 |
| Wu, H | 1 |
| Brennan, KJM | 1 |
| Cassoulet, R | 1 |
| Wilkie, E | 1 |
| Gillet, V | 1 |
| Desautels, AS | 1 |
| Abdelouahab, N | 1 |
| Bellenger, JP | 1 |
| Burris, HH | 1 |
| Coull, BA | 1 |
| Weisskopf, MG | 1 |
| Zhang, W | 4 |
| Takser, L | 1 |
| Baccarelli, AA | 2 |
| Stanford, JB | 1 |
| Plowden, TC | 1 |
| Oliphant, EA | 2 |
| McKinlay, CJ | 1 |
| McNamara, D | 1 |
| Cavadino, A | 1 |
| Alsweiler, JM | 2 |
| Gur, EY | 1 |
| Cil, MA | 1 |
| Apay, SE | 1 |
| Lau, CI | 1 |
| Wang, YF | 1 |
| Chen, B | 2 |
| Zhang, M | 1 |
| He, Y | 1 |
| Si, Y | 1 |
| Shi, Y | 2 |
| Jiang, K | 1 |
| Shen, J | 1 |
| Hong, J | 1 |
| Ni, S | 1 |
| Rao, W | 1 |
| Li, Y | 5 |
| Li, N | 5 |
| Yao, Q | 1 |
| Mitro, SD | 1 |
| Gilman, SE | 1 |
| Newman, RB | 1 |
| Hunt, KJ | 1 |
| Skupski, DW | 1 |
| Grobman, WA | 1 |
| Nageotte, M | 1 |
| Robinson, M | 2 |
| Kannan, K | 2 |
| Agarwal, K | 1 |
| Manza, P | 2 |
| Tejeda, HA | 1 |
| Courville, AB | 1 |
| Volkow, ND | 2 |
| Joseph, PV | 1 |
| Sahoo, S | 1 |
| Behura, SS | 1 |
| Wasiq, MA | 1 |
| Nayak, MK | 1 |
| Mishra, A | 1 |
| Panda, SK | 1 |
| Chen, LW | 5 |
| Lee-Sarwar, KA | 3 |
| Chen, YC | 3 |
| Lasky-Su, J | 3 |
| Kelly, RS | 3 |
| Zeiger, RS | 3 |
| O'Connor, GT | 3 |
| Bacharier, LB | 3 |
| Jia, X | 3 |
| Beigelman, A | 3 |
| Gold, DR | 3 |
| Laranjo, N | 3 |
| Bunyavanich, S | 3 |
| Weiss, ST | 3 |
| Litonjua, AA | 3 |
| Brennan, PJ | 3 |
| Liu, Y | 8 |
| Zhu, J | 2 |
| Qu, H | 2 |
| Zhou, S | 3 |
| Chen, M | 2 |
| Crowe, HM | 1 |
| Wesselink, AK | 2 |
| Wise, LA | 3 |
| Jick, SS | 1 |
| Rothman, KJ | 3 |
| Mikkelsen, EM | 3 |
| Sørensen, HT | 3 |
| Hatch, EE | 5 |
| Román-Gálvez, MR | 1 |
| Martín-Peláez, S | 1 |
| Hernández-Martínez, L | 1 |
| Cano-Ibáñez, N | 1 |
| Olmedo-Requena, R | 2 |
| Martínez-Galiano, JM | 1 |
| Bueno-Cavanillas, A | 2 |
| Amezcua-Prieto, C | 1 |
| Williford, EM | 1 |
| Howley, MM | 1 |
| Fisher, SC | 1 |
| Conway, KM | 1 |
| Romitti, PA | 7 |
| Reeder, MR | 1 |
| Olshan, AF | 1 |
| Reefhuis, J | 2 |
| Browne, ML | 8 |
| Wootton, RE | 1 |
| Lawn, RB | 1 |
| Magnus, MC | 1 |
| Treur, JL | 1 |
| Corfield, EC | 1 |
| Njølstad, PR | 1 |
| Andreassen, OA | 1 |
| Lawlor, DA | 1 |
| Håberg, SE | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Aspirin in Gestation and Reproduction: A Multi-center, Controlled, Double-blind Randomized Trial.[NCT00467363] | 1,228 participants (Actual) | Interventional | 2007-06-30 | Completed | |||
| Caffeine for Late Preterm Infants: A Double Blind Randomized Controlled Trial[NCT06026163] | Phase 2/Phase 3 | 134 participants (Anticipated) | Interventional | 2023-10-31 | Not yet recruiting | ||
| Treatment With Caffeine of Very Preterm Infant in the Delivery Room: the CAFROOM Feasibility Study[NCT04044976] | 42 participants (Actual) | Interventional | 2019-08-01 | Completed | |||
| Caffeine in the Second Stage: A Randomized Control Trial in Low-risk Nulliparous Mothers at Term[NCT05906303] | Phase 1 | 80 participants (Anticipated) | Interventional | 2023-12-01 | Not yet recruiting | ||
| Human Exposure to Bisphenol A, Phthalates and Fertility, Pregnancy Outcomes.[NCT00011713] | 1,474 participants (Actual) | Observational | 1999-10-31 | Completed | |||
| Assessment of Blood Pressure and Endothelial Function Pregnancy After Acute and Daily Consumption Flavanol-rich Chocolate Among Healthy Pregnant Women: a Pilot Randomized Controlled Trial[NCT01659060] | Phase 2 | 44 participants (Actual) | Interventional | 2008-07-31 | Completed | ||
| The Effect of Guided Counseling in Improving Dietary Practice, Nutritional Status and Birth Weight of Pregnant Women in West Gojjam Zone, Amhara Region, Ethiopia: A Cluster Randomized Controlled Community Trial[NCT03627156] | 712 participants (Actual) | Interventional | 2018-05-01 | Completed | |||
| High Versus Low Dose Caffeine as Respiratory Stimulant in Preterm Infants[NCT04144712] | Phase 1 | 80 participants (Anticipated) | Interventional | 2019-04-01 | Recruiting | ||
| Assessment of the Effectiveness of the Healthy Living Awareness Program for the Prevention of Osteoporosis Based on the Information- Motivation- Behavioral Skills Model in University Students: A Randomized Controlled Trial[NCT06028243] | 87 participants (Actual) | Interventional | 2021-03-26 | Completed | |||
| "Influence of Espresso on Adsorption of Orally Administrated Myo-inositol in Humans"[NCT01244399] | 12 participants (Actual) | Observational | 2010-11-30 | Completed | |||
| The Effect of Caffeine on the Narcoleptic Patients Randomized Controlled Clinical Trial[NCT02832336] | Phase 1/Phase 2 | 16 participants (Actual) | Interventional | 2016-10-01 | Completed | ||
| Is the Exhaled Nitric Oxide in Infants a Predictive Marker of Asthma?[NCT01239199] | 86 participants (Actual) | Interventional | 2010-01-31 | Completed | |||
| Neuroplastic Alterations of the Motor Cortex by Caffeine: Differences Between Caffeine and Non-caffeine Users and Influence of Vigilance During Stimulation[NCT04011670] | 30 participants (Actual) | Interventional | 2019-07-15 | Completed | |||
| Effect of Coffee and Tea Consumption on Adolescent Weight Control - a Randomized Clinical Trial[NCT05181176] | 63 participants (Anticipated) | Interventional | 2021-01-01 | Recruiting | |||
| Cortical Excitability Changes on the Sensorimotor Cortex Induced by Caffeine Consumption: A TMS Study[NCT03720665] | 30 participants (Actual) | Interventional | 2018-10-01 | Completed | |||
| The Importance of Caffeine in Fetal Growth[NCT00131690] | Phase 4 | 1,200 participants | Interventional | 1996-04-30 | Completed | ||
| Effect of the Administration of Chlorogenic Acid on Glucemic Control, Insulin Secretion and Insulin Sensitivity in Patients With Impaired Glucose Tolerance[NCT02621060] | Phase 2 | 30 participants (Actual) | Interventional | 2015-09-30 | Completed | ||
| CID 0708 - Sex, Aging and Antiretroviral Pharmacokinetics[NCT00666055] | 11 participants (Actual) | Observational | 2008-03-31 | Completed | |||
| Chronic Headache and Chronic Backache Following Unintentional Dural Puncture at Delivery Room[NCT03908424] | 389 participants (Actual) | Observational | 2019-05-01 | Completed | |||
| Phase III Study Comparing Coristina® D to Resfenol® in the Symptomatic Treatment of Common Cold[NCT02735070] | Phase 3 | 366 participants (Anticipated) | Interventional | 2016-09-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Partial or complete abruption (ie, premature separation of the placenta) (NCT00467363)
Timeframe: until delivery
| Intervention | participants (Number) |
|---|---|
| Aspirin | 7 |
| Placebo | 5 |
(NCT00467363)
Timeframe: 8-weeks
| Intervention | pregnancy (Number) |
|---|---|
| Aspirin | 374 |
| Placebo | 346 |
Implantation failures (NCT00467363)
Timeframe: 8 weeks
| Intervention | pregnancy (Number) |
|---|---|
| Aspirin | 28 |
| Placebo | 27 |
(NCT00467363)
Timeframe: within 6 weeks
| Intervention | pregnancy (Number) |
|---|---|
| Aspirin | 3 |
| Placebo | 3 |
(NCT00467363)
Timeframe: until 40 weeks
| Intervention | pregnancy (Number) |
|---|---|
| Aspirin | 4 |
| Placebo | 6 |
(NCT00467363)
Timeframe: within 8-weeks of gestation
| Intervention | pregnancy (Number) |
|---|---|
| Aspirin | 394 |
| Placebo | 363 |
Live birth was obtained prospectively by maternal report and abstraction from medical records by trained staff . (NCT00467363)
Timeframe: after delivery
| Intervention | livebirths (Number) |
|---|---|
| Aspirin | 309 |
| Placebo | 286 |
(NCT00467363)
Timeframe: 8 weeks
| Intervention | pregnancy (Number) |
|---|---|
| Aspirin | 0 |
| Placebo | 0 |
(NCT00467363)
Timeframe: until delivery
| Intervention | participants (Number) |
|---|---|
| Aspirin | 32 |
| Placebo | 30 |
Includes preembryonic and embryonic losses (exclusive of implantation failures) (NCT00467363)
Timeframe: less than 10-weeks
| Intervention | pregnancy (Number) |
|---|---|
| Aspirin | 56 |
| Placebo | 53 |
(NCT00467363)
Timeframe: until delivery
| Intervention | infants (Number) |
|---|---|
| Aspirin | 22 |
| Placebo | 31 |
birthweight (NCT00467363)
Timeframe: until delivery
| Intervention | grams (Mean) |
|---|---|
| Aspirin | 3327 |
| Placebo | 3315 |
(NCT00467363)
Timeframe: 40 weeks
| Intervention | participants (Number) |
|---|---|
| Aspirin | 2 |
| Placebo | 2 |
Subjects underwent a 2-h oral glucose tolerance test (2-h OGTT) by consuming 75-g of a dextrose load, and one sample was obtained 120 min after glucose administration. (NCT02621060)
Timeframe: Week 12.
| Intervention | mmol/L (Mean) |
|---|---|
| Placebo | 9.0 |
| Chlorogenic Acid | 8.5 |
Area under the curve of glucose was obtained using the trapezoidal integration. (NCT02621060)
Timeframe: Week 12.
| Intervention | mmol/l/min (Mean) |
|---|---|
| Placebo | 1187 |
| Chlorogenic Acid | 1145 |
Before and after intervention area under the curve of insulin (NCT02621060)
Timeframe: Week 12.
| Intervention | pmol/L/min (Mean) |
|---|---|
| Placebo | 67,322 |
| Chlorogenic Acid | 72,857 |
The Body Mass index was calculated at baseline and at week 12 with the Quetelet index and the entered values reflect the body mass index at week 12 (NCT02621060)
Timeframe: Week 12.
| Intervention | kg/m^2 (Mean) |
|---|---|
| Placebo | 32.0 |
| Chlorogenic Acid | 31.4 |
The weight was measured at baseline, week 4, week 8 and week 12 with a bioimpedance balance and the entered values reflect the weight at week 12 (NCT02621060)
Timeframe: Week 12.
| Intervention | kg (Mean) |
|---|---|
| Placebo | 81.3 |
| Chlorogenic Acid | 80.8 |
The creatinine levels were measured at baseline and at week 12 with standardized techniques and the entered values reflect the uric acid levels at week 12 (NCT02621060)
Timeframe: Week 12.
| Intervention | mmol/L (Mean) |
|---|---|
| Placebo | 0.06 |
| Chlorogenic Acid | 0.06 |
The Diastolic blood plessure was evaluated at baseline and week 12 with a digital sphygmomanometer and the entered values reflect the blood pressure at week 12 (NCT02621060)
Timeframe: Week 12.
| Intervention | mmHg (Mean) |
|---|---|
| Placebo | 78 |
| Chlorogenic Acid | 74 |
Reflect the fasting glucose level after a 10- to 12-h overnight fast. (NCT02621060)
Timeframe: Week 12.
| Intervention | mmol/L (Median) |
|---|---|
| Placebo | 5.8 |
| Chlorogenic Acid | 5.5 |
After intervention with Stumvoll index (NCT02621060)
Timeframe: Week 12.
| Intervention | Unitless (Mean) |
|---|---|
| Placebo | 1281 |
| Chlorogenic Acid | 1133 |
Before and after intervention by spectrophotometry (NCT02621060)
Timeframe: Week 12.
| Intervention | IU/L (Mean) |
|---|---|
| Placebo | 22.03 |
| Chlorogenic Acid | 17.79 |
Before and after intervention by spectrophotometry (NCT02621060)
Timeframe: Week 12.
| Intervention | IU/L (Mean) |
|---|---|
| Placebo | 25.25 |
| Chlorogenic Acid | 22.64 |
Shows what a person's average blood glucose level was for the 2 to 3 months before the test high-performance. (NCT02621060)
Timeframe: Week 12.
| Intervention | Percentage of A1C (Mean) |
|---|---|
| Placebo | 5.8 |
| Chlorogenic Acid | 5.5 |
The HDL-C levels were evaluated at baseline and week 12 with enzymatic/colorimetric techniques and the entered values reflect the HDL-C level at week 12 (NCT02621060)
Timeframe: Week 12.
| Intervention | mmol/L (Mean) |
|---|---|
| Placebo | 1.5 |
| Chlorogenic Acid | 1.8 |
After intervention Matsuda Index (NCT02621060)
Timeframe: Week 12.
| Intervention | Unitless (Mean) |
|---|---|
| Placebo | 2.43 |
| Chlorogenic Acid | 2.30 |
The LDL-C levels were measured at baseline and at week 12 with standardized techniques and the entered values reflect the LDL-C levels at week 12 (NCT02621060)
Timeframe: Week 12.
| Intervention | mmol/L (Mean) |
|---|---|
| Placebo | 2.7 |
| Chlorogenic Acid | 1.9 |
The Systolic Blood Pressure was evaluated at baseline and week 12 with a digital sphygmomanometer and the entered values reflect the blood pressure at week 12 (NCT02621060)
Timeframe: Week 12.
| Intervention | mmHg (Mean) |
|---|---|
| Placebo | 118 |
| Chlorogenic Acid | 113 |
The total cholesterol was estimated by standardized techniques at baseline and week 12 and the entered values reflect the total cholesterol level at week 12 (NCT02621060)
Timeframe: Week 12.
| Intervention | mmol/L (Mean) |
|---|---|
| Placebo | 5.3 |
| Chlorogenic Acid | 4.3 |
After intervention. Total insulin secretion was calculated with the Insulinogenic index (Δ ABC insulin / Δ ABC glucose). (NCT02621060)
Timeframe: Week 12.
| Intervention | Unitless (Mean) |
|---|---|
| Placebo | 0.55 |
| Chlorogenic Acid | 0.63 |
The triglycerides were evaluated at baseline and week 12 with enzymatic-colorimetric techniques and the entered values reflect the triglycerides level at week 12 (NCT02621060)
Timeframe: Week 12.
| Intervention | mmol/L (Mean) |
|---|---|
| Placebo | 1.7 |
| Chlorogenic Acid | 1.3 |
The uric acid levels were measured at baseline and at week 12 with standardized techniques and the entered values reflect the creatinina levels at week 12. (NCT02621060)
Timeframe: Week 12.
| Intervention | mmol/l (Mean) |
|---|---|
| Placebo | 0.34 |
| Chlorogenic Acid | 0.30 |
The VLDL levels were measured at baseline and at week 12 with standardized techniques and the entered values reflect the c-LDL levels at week 12 (NCT02621060)
Timeframe: Week 12.
| Intervention | mmol/L (Mean) |
|---|---|
| Placebo | 0.77 |
| Chlorogenic Acid | 0.61 |
Waist circumference was evaluated at baseline and at week 12 with a flexible tape and the entered values reflects the waist circumference measure at week 12 (NCT02621060)
Timeframe: Week 12.
| Intervention | cm (Mean) |
|---|---|
| Placebo | 102 |
| Chlorogenic Acid | 104 |
126 reviews available for caffeine and Pregnancy
| Article | Year |
|---|---|
The impact of paternal alcohol, tobacco, caffeine use and physical activity on offspring mental health: a systematic review and meta-analysis.
Topics: Alcohol Drinking; Caffeine; Exercise; Humans; Mental Health; Nicotiana; Pregnancy; Risk Factors; Tob | 2021 |
Prenatal smoking, alcohol and caffeine exposure and offspring externalizing disorders: a systematic review and meta-analysis.
Topics: Attention Deficit Disorder with Hyperactivity; Caffeine; Conduct Disorder; Ethanol; Female; Humans; | 2022 |
Dietary sources, health benefits, and risks of caffeine.
Topics: Adolescent; Caffeine; Child; Diabetes Mellitus; Diet; Female; Humans; Migraine Disorders; Obesity; P | 2023 |
Coffee consumption during pregnancy - what the gynecologist should know? Review of the literature and clinical studies.
Topics: Caffeine; Coffee; Female; Humans; Infant, Newborn; Pregnancy | 2022 |
The association between caffeine exposure during pregnancy and risk of gestational hypertension/preeclampsia: A meta-analysis and systematical review.
Topics: Caffeine; Female; Humans; Hypertension, Pregnancy-Induced; Odds Ratio; Pre-Eclampsia; Pregnancy | 2022 |
The association between caffeine and alcohol consumption and IVF/ICSI outcomes: A systematic review and dose-response meta-analysis.
Topics: Alcohol Drinking; Caffeine; Female; Fertilization in Vitro; Humans; Live Birth; Male; Pregnancy; Pre | 2022 |
Paternal Nicotine/Ethanol/Caffeine Mixed Exposure Induces Offspring Rat Dysplasia and Its Potential "GC-IGF1" Programming Mechanism.
Topics: Animals; Caffeine; Corticosterone; Ethanol; Female; Hypothalamo-Hypophyseal System; Insulin-Like Gro | 2022 |
Paternal Nicotine/Ethanol/Caffeine Mixed Exposure Induces Offspring Rat Dysplasia and Its Potential "GC-IGF1" Programming Mechanism.
Topics: Animals; Caffeine; Corticosterone; Ethanol; Female; Hypothalamo-Hypophyseal System; Insulin-Like Gro | 2022 |
Paternal Nicotine/Ethanol/Caffeine Mixed Exposure Induces Offspring Rat Dysplasia and Its Potential "GC-IGF1" Programming Mechanism.
Topics: Animals; Caffeine; Corticosterone; Ethanol; Female; Hypothalamo-Hypophyseal System; Insulin-Like Gro | 2022 |
Paternal Nicotine/Ethanol/Caffeine Mixed Exposure Induces Offspring Rat Dysplasia and Its Potential "GC-IGF1" Programming Mechanism.
Topics: Animals; Caffeine; Corticosterone; Ethanol; Female; Hypothalamo-Hypophyseal System; Insulin-Like Gro | 2022 |
Impacts of Caffeine during Pregnancy.
Topics: Animals; Caffeine; Epigenesis, Genetic; Female; Humans; Maternal Nutritional Physiological Phenomena | 2020 |
Evidence base multi-discipline critical strategies toward better tomorrow for very preterm infants.
Topics: Anti-Bacterial Agents; Bronchopulmonary Dysplasia; Budesonide; Caffeine; Central Nervous System Stim | 2020 |
Relationship between caffeine intake and infertility: a systematic review of controlled clinical studies.
Topics: Caffeine; Child; Controlled Clinical Trials as Topic; Female; Fertility; Humans; Infertility, Female | 2020 |
Maternal caffeine consumption and pregnancy outcomes: a narrative review with implications for advice to mothers and mothers-to-be.
Topics: Caffeine; Child; Female; Humans; Infant, Newborn; Mothers; Pregnancy; Pregnancy Outcome; Premature B | 2021 |
Pharmacological Neuroprotection of the Preterm Brain: Current Evidence and Perspectives.
Topics: Brain; Caffeine; Erythropoietin; Female; Humans; Infant, Newborn; Infant, Premature; Neuroprotection | 2022 |
Maternal diet and offspring telomere length: a systematic review.
Topics: Adult; Caffeine; Calcifediol; Child; Child, Preschool; Diet; Eating; Fatty Acids, Omega-3; Female; F | 2021 |
What is bronchopulmonary dysplasia and does caffeine prevent it?
Topics: Bronchopulmonary Dysplasia; Caffeine; Central Nervous System Stimulants; Citrates; Dose-Response Rel | 2020 |
Caffeine exposure during pregnancy: Is it safe?
Topics: Caffeine; Central Nervous System Stimulants; Child Development; Female; Humans; Infant, Newborn; Pre | 2020 |
Mechanisms underlying cognitive impairment induced by prenatal caffeine exposure.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Cognitive Dysfunction; Female; Fetal Developme | 2020 |
Foetal ductus arteriosus constriction unrelated to non-steroidal anti-Inflammatory drugs: a case report and literature review.
Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Cesarean Section; Constriction; C | 2021 |
Maternal caffeine consumption during pregnancy and risk of low birth weight: a dose-response meta-analysis of cohort studies.
Topics: Caffeine; Cohort Studies; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Pregnancy | 2023 |
Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children.
Topics: Adolescent; Adolescent Health; Adult; Caffeine; Child; Child Health; Female; Humans; Male; Pregnancy | 2017 |
A review of caffeine use as a risk or protective factor for women's health and pregnancy.
Topics: Caffeine; Female; Humans; Pregnancy; Pregnant Women; Protective Factors; Retrospective Studies; Risk | 2017 |
Coffee, Caffeine, and Health Outcomes: An Umbrella Review.
Topics: Caffeine; Cardiovascular Diseases; Coffee; Diabetes Mellitus, Type 2; Female; Humans; Male; Neoplasm | 2017 |
Diet and fertility: a review.
Topics: Alcohol Drinking; Animals; Antioxidants; Caffeine; Central Nervous System Stimulants; Diet; Dietary | 2018 |
Optimizing Caffeine Use and Risk of Bronchopulmonary Dysplasia in Preterm Infants: A Systematic Review, Meta-analysis, and Application of Grading of Recommendations Assessment, Development, and Evaluation Methodology.
Topics: Adult; Bronchopulmonary Dysplasia; Caffeine; Confidence Intervals; Dose-Response Relationship, Drug; | 2018 |
Biases Inherent in Studies of Coffee Consumption in Early Pregnancy and the Risks of Subsequent Events.
Topics: Abortion, Spontaneous; Bias; Caffeine; Coffee; Female; Humans; Infant, Low Birth Weight; Maternal-Fe | 2018 |
Caffeine, alcohol, smoking, and reproductive outcomes among couples undergoing assisted reproductive technology treatments.
Topics: Alcohol Drinking; Caffeine; Central Nervous System Stimulants; Female; Humans; Male; Pregnancy; Preg | 2018 |
Effects of maternal caffeine consumption on the breastfed child: a systematic review.
Topics: Breast Feeding; Caffeine; Central Nervous System Stimulants; Female; Heart Rate; Humans; Infant; Mil | 2018 |
Drugs for the Prevention and Treatment of Bronchopulmonary Dysplasia.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Bronchodilator Agents; Bronchopulmonary Dysplas | 2019 |
Bronchopulmonary dysplasia: a review.
Topics: Adrenal Cortex Hormones; Birth Weight; Bronchopulmonary Dysplasia; Caffeine; Female; Gestational Age | 2013 |
Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcome.
Topics: Birth Weight; Caffeine; Central Nervous System Stimulants; Coffee; Female; Humans; Pregnancy; Pregna | 2013 |
The Janus face of caffeine.
Topics: Animals; Behavior, Animal; Brain; Caffeine; Central Nervous System Stimulants; Cognition Disorders; | 2013 |
Factors that increase reactivity during fetal nonstress testing.
Topics: Acoustic Stimulation; Cacao; Caffeine; Candy; False Negative Reactions; Female; Fetal Distress; Feta | 2014 |
Caffeine intake during pregnancy and adverse birth outcomes: a systematic review and dose-response meta-analysis.
Topics: Abortion, Spontaneous; Birth Weight; Caffeine; Female; Humans; Infant, Small for Gestational Age; Pr | 2014 |
Maternal caffeine intake during pregnancy is associated with risk of low birth weight: a systematic review and dose-response meta-analysis.
Topics: Birth Weight; Caffeine; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Male; Pregnancy; | 2014 |
Preconception care: caffeine, smoking, alcohol, drugs and other environmental chemical/radiation exposure.
Topics: Alcohol Drinking; Caffeine; Environmental Exposure; Female; Humans; Maternal Exposure; Preconception | 2014 |
Caffeine as an analgesic adjuvant for acute pain in adults.
Topics: Acetaminophen; Acute Pain; Adolescent; Adult; Aged; Analgesics; Caffeine; Chemotherapy, Adjuvant; Di | 2014 |
[Caffeine consumption during pregnancy and attention deficit hyperactivity disorder (ADHD): a systematic literature review].
Topics: Attention Deficit Disorder with Hyperactivity; Brazil; Caffeine; Central Nervous System Stimulants; | 2015 |
A meta-analysis of risk of pregnancy loss and caffeine and coffee consumption during pregnancy.
Topics: Abortion, Spontaneous; Caffeine; Coffee; Dose-Response Relationship, Drug; Female; Humans; Pregnancy | 2015 |
Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcomes.
Topics: Birth Weight; Caffeine; Central Nervous System Stimulants; Coffee; Female; Humans; Infant, Newborn; | 2015 |
Maternal Caffeine Consumption during Pregnancy and Risk of Low Birth Weight: A Dose-Response Meta-Analysis of Observational Studies.
Topics: Birth Weight; Caffeine; Coffee; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Pregnancy | 2015 |
Maternal and childhood consumption of coffee, tea and cola beverages in association with childhood leukemia: a meta-analysis.
Topics: Beverages; Caffeine; Case-Control Studies; Child; Coffee; Female; Humans; Precursor Cell Lymphoblast | 2015 |
Maternal caffeine intake during pregnancy and risk of pregnancy loss: a categorical and dose-response meta-analysis of prospective studies.
Topics: Abortion, Spontaneous; Caffeine; Coffee; Databases, Factual; Dose-Response Relationship, Drug; Femal | 2016 |
Optimizing Care of the Preterm Infant Starting in the Delivery Room.
Topics: Blood Pressure; Blood Transfusion; Caffeine; Central Nervous System Stimulants; Constriction; Delive | 2016 |
Caffeine: Friend or Foe?
Topics: Adolescent; Adult; Behavior; Caffeine; Cardiovascular System; Diet; Female; Fetal Development; Fetus | 2016 |
Clinical Inquiry: Does caffeine intake during pregnancy affect birth weight?
Topics: Adult; Birth Weight; Caffeine; Coffee; Cohort Studies; Dose-Response Relationship, Drug; Female; Ges | 2016 |
[Changes of carbohydrate and lipid metabolism in women during pregnancy taking caffeine].
Topics: Caffeine; Carbohydrate Metabolism; Female; Humans; Lipid Metabolism; Pregnancy | 2017 |
[Caffeine and adaptive changes in the circulatory system during pregnancy].
Topics: Caffeine; Cardiovascular System; Female; Fetus; Humans; Pregnancy | 2017 |
Optimizing natural fertility.
Topics: Aging; Alcohol Drinking; Caffeine; Coitus; Diet; Female; Fertility; Humans; Life Style; Male; Ovulat | 2008 |
Caffeine in pregnancy.
Topics: Cacao; Caffeine; Coffee; Female; Humans; Pregnancy; Pregnancy Complications; Tea | 2009 |
Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcome.
Topics: Birth Weight; Caffeine; Central Nervous System Stimulants; Coffee; Female; Humans; Pregnancy; Pregna | 2009 |
Peripartum implications of caffeine intake in pregnancy: is there cause for concern?
Topics: Abnormalities, Drug-Induced; Adult; Animals; Beverages; Caffeine; Dose-Response Relationship, Drug; | 2009 |
Caffeine consumption during pregnancy and risk of preterm birth: a meta-analysis.
Topics: Caffeine; Female; Humans; Obstetric Labor, Premature; Odds Ratio; Plant Preparations; Pregnancy; Pre | 2010 |
Methylxanthines during pregnancy and early postnatal life.
Topics: Animals; Caffeine; Female; Fetus; Humans; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, G | 2011 |
Adverse and protective influences of adenosine on the newborn and embryo: implications for preterm white matter injury and embryo protection.
Topics: Adenosine; Animals; Caffeine; Embryo, Mammalian; Female; Humans; Hypoxia-Ischemia, Brain; Infant, Ne | 2011 |
Evaluation of the reproductive and developmental risks of caffeine.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Caffeine; Congenital Abnormalities; Fem | 2011 |
[Prophylaxis and therapy of postdural puncture headache--a critical evaluation of treatment options].
Topics: Adrenocorticotropic Hormone; Adult; Analgesics; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthe | 2011 |
[Nutrition and miscarriages: a literature review].
Topics: Abortion, Spontaneous; Alcohol Drinking; Caffeine; Celiac Disease; Dietary Supplements; Embryo Impla | 2012 |
Caffeine as an analgesic adjuvant for acute pain in adults.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics; Caffeine; Chemotherapy, Adjuvant; Female; Headache; Hu | 2012 |
[Caffeine--common ingredient in a diet and its influence on human health].
Topics: Adolescent; Adult; Brain; Caffeine; Cardiovascular Diseases; Central Nervous System Stimulants; Chil | 2012 |
Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus.
Topics: Beverages; Blood Glucose; Caffeine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes, | 2013 |
A review of the literature relating caffeine consumption by women to their risk of reproductive hazards.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Caffeine; Central Nervous System Stimulan | 2002 |
Effects of caffeine on human health.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Bone and Bones; Caffeine; Calcium; Cardiovascula | 2003 |
Maternal lifestyle factors in pregnancy risk of attention deficit hyperactivity disorder and associated behaviors: review of the current evidence.
Topics: Adolescent; Adult; Alcohol Drinking; Attention Deficit Disorder with Hyperactivity; Caffeine; Child; | 2003 |
Anesthetic implications of drug abuse in pregnancy.
Topics: Adult; Amphetamine-Related Disorders; Anesthesia; Caffeine; Cocaine-Related Disorders; Female; Hallu | 2003 |
Social drug use in the parturient: implications for the management of obstetrical anaesthesia.
Topics: Anesthesia, Obstetrical; Caffeine; Central Nervous System Depressants; Central Nervous System Stimul | 2003 |
Maternal caffeine consumption and spontaneous abortion: a review of the epidemiologic evidence.
Topics: Abortion, Spontaneous; Caffeine; Cross-Sectional Studies; Epidemiologic Methods; Female; Gestational | 2004 |
[The effect of caffeine on hypertension].
Topics: Adult; Aged; Blood Pressure; Caffeine; Central Nervous System Stimulants; Coffee; Female; Humans; Hy | 2005 |
Caffeine metabolism, genetics, and perinatal outcomes: a review of exposure assessment considerations during pregnancy.
Topics: Caffeine; Female; Fetal Development; Gestational Age; Humans; Maternal Exposure; Perinatal Care; Pol | 2005 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Maternal exposure to caffeine and risk of congenital anomalies: a systematic review.
Topics: Adolescent; Adult; Caffeine; Congenital Abnormalities; Female; Humans; Pregnancy; Risk Assessment; T | 2006 |
Dietary effects on fertility treatment and pregnancy outcomes.
Topics: Alcohol Drinking; Blood Glucose; Body Weight; Caffeine; Central Nervous System Stimulants; Diet; Die | 2007 |
[Caffeine consumption during pregnancy and prevalence of low birth weight and prematurity: a systematic review].
Topics: Beverages; Caffeine; Clinical Trials as Topic; Cohort Studies; Female; Fetal Growth Retardation; Ges | 2007 |
Theophylline reassessed.
Topics: Acidosis; Aging; Allopurinol; Animals; Anti-Bacterial Agents; Breast Feeding; Bronchodilator Agents; | 1984 |
Sperm motility.
Topics: Alcoholism; Androgens; Caffeine; Carnitine; Chorionic Gonadotropin; Coitus; Cyclic AMP; Ejaculation; | 1980 |
Caffeine: a survey of some of the known and suspected deleterious effects of habitual use.
Topics: Abnormalities, Drug-Induced; Anxiety Disorders; Behavior Therapy; Caffeine; Coffee; Diagnosis, Diffe | 1983 |
Maternal alcohol use and neonatal habituation assessed with the Brazelton scale.
Topics: Adult; Alcohol Drinking; Arousal; Caffeine; Ethanol; Female; Habituation, Psychophysiologic; Humans; | 1983 |
Caffeine: implications of recent research for clinical practice.
Topics: Abnormalities, Drug-Induced; Affective Symptoms; Animals; Blood Pressure; Brain; Caffeine; Child; De | 1984 |
Effects of drugs and chemicals on the fetus and newborn (1).
Topics: Abnormalities, Drug-Induced; Animals; Antiemetics; Behavior; Caffeine; Dicyclomine; Doxylamine; Drug | 1984 |
Drug exposure during pregnancy: some epidemiologic considerations.
Topics: Abnormalities, Drug-Induced; Benzodiazepines; Caffeine; Dicyclomine; Doxylamine; Drug Combinations; | 1983 |
Caffeine.
Topics: Adult; Age Factors; Animals; Behavior, Animal; Birth Weight; Caffeine; Cardiovascular System; Centra | 1982 |
Sister chromatid exchange analysis.
Topics: Animals; Caffeine; Carcinogens; Chromosome Aberrations; Chromosome Banding; Chromosome Disorders; Cr | 1980 |
Effects of sex steroids on ethanol pharmacokinetics and autonomic reactivity.
Topics: Alcohol Drinking; Animals; Caffeine; Castration; Drug Interactions; Estrogens; Ethanol; Female; Gona | 1981 |
Case-control study of caffeinated beverages and preterm delivery.
Topics: Adult; Beverages; Caffeine; Case-Control Studies; Female; Humans; North Carolina; Obstetric Labor, P | 1995 |
Nutrition during pregnancy.
Topics: Caffeine; Cost-Benefit Analysis; Fatty Acids, Omega-3; Female; Folic Acid; Humans; Nutrition Policy; | 1994 |
Caffeine, health and commercial interests.
Topics: Caffeine; Cardiovascular Diseases; Female; Fetal Growth Retardation; Health Education; Humans; Infan | 1994 |
Determinants of fetal and neonatal growth.
Topics: Caffeine; Cell Differentiation; Cell Division; Embryonic and Fetal Development; Energy Metabolism; F | 1994 |
[Effects of coffee and caffeine on fertility, reproduction, lactation, and development. Review of human and animal data].
Topics: Animals; Caffeine; Child Development; Coffee; Disease Models, Animal; Dose-Response Relationship, Dr | 1994 |
Consequences on the newborn of chronic maternal consumption of coffee during gestation and lactation: a review.
Topics: Behavior; Caffeine; Coffee; Female; Humans; Infant, Newborn; Lactation; Milk, Human; Pregnancy; Pren | 1994 |
Reproduction and caffeine consumption--a literature review.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Administration, Oral; Animals; Caffeine; Chick E | 1995 |
Caffeine consumption.
Topics: Adolescent; Adult; Aged; Australia; Beverages; Cacao; Caffeine; Child; Child, Preschool; Coffee; Den | 1996 |
[Should one consider monitoring various products containing caffeine?].
Topics: Beverages; Caffeine; Carcinogens; Cardiovascular System; Central Nervous System; Female; Food; Human | 1996 |
The effect of caffeine on pregnancy outcome variables.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Caffeine; Dose-Response Relationship, Drug; Fema | 1996 |
Nutrition during pregnancy.
Topics: Caffeine; Constipation; Female; Humans; Lactose Intolerance; Nausea; Nutrition Assessment; Nutrition | 1997 |
Choices for achieving adequate dietary calcium with a vegetarian diet.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biological Availability; Caffeine; Calcium, Dietary; Chi | 1999 |
[Teratogenic and embryotoxic effects of caffeine: facts and hypotheses].
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Female; Humans; Maternal-Fetal Exchange; Pregnancy; | 2000 |
[Teratology, 40 years after the thalidomide tragedy].
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Abortion, Spontaneous; Animals; Caffe | 2001 |
Teratogen update: evaluation of the reproductive and developmental risks of caffeine.
Topics: Abortion, Spontaneous; Animals; Animals, Newborn; Behavior; Caffeine; Central Nervous System; Coffee | 2001 |
Environmental factors and disturbances of brain development.
Topics: Brain; Brain Injuries; Caffeine; Cocaine; Environmental Pollutants; Ethanol; Female; Humans; Infant, | 2001 |
Nausea and vomiting of pregnancy: endocrine basis and contribution to pregnancy outcome.
Topics: Abortion, Spontaneous; Alcohol Drinking; Caffeine; Chorionic Gonadotropin; Congenital Abnormalities; | 2001 |
In vitro fertilization and embryo development in pigs.
Topics: Animals; Bicarbonates; Caffeine; Calcium; Cells, Cultured; Culture Media; Embryo Transfer; Embryo, M | 2001 |
Drugs in pregnancy: effects on the fetus and newborn.
Topics: Analgesics; Anti-Inflammatory Agents; Anticoagulants; Anticonvulsants; Antihypertensive Agents; Anti | 1979 |
Effects of methylxanthines on the fetus.
Topics: Animals; Caffeine; Cyclic AMP; Female; Fetus; Humans; Intestinal Absorption; Kinetics; Labor, Obstet | 1979 |
Caffeine--its identity, dietary sources, intake and biological effects.
Topics: Adolescent; Adult; Aged; Animals; Cacao; Caffeine; Carbonated Beverages; Chemical Phenomena; Chemist | 1978 |
Physiological disposition of caffeine.
Topics: Animals; Caffeine; Dogs; Female; Guinea Pigs; Half-Life; Haplorhini; Humans; Intestinal Absorption; | 1975 |
Drug metabolism in the human neonate.
Topics: Adult; Animals; Barbiturates; Caffeine; Epoxy Compounds; Female; Humans; Infant, Newborn; Labor, Obs | 1975 |
Reproductive effects of caffeine: a review and theoretical analysis.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Caffeine; Female; Humans; Infertility; | 1992 |
[Harmful substances and infertility. Substances of abuse].
Topics: Alcohol Drinking; Caffeine; Female; Humans; Infant, Newborn; Infertility, Female; Infertility, Male; | 1992 |
[Relationship between congenital heart disease and various factors affecting pregnancy].
Topics: Alcohol Drinking; Caffeine; Contraceptives, Oral, Hormonal; Diagnosis, Computer-Assisted; Female; He | 1992 |
Effects of maternal drug addiction on the fetus.
Topics: Abnormalities, Drug-Induced; Alcoholism; Amphetamines; Benzodiazepines; Caffeine; Cocaine; Female; F | 1991 |
Neurobehavioral effects of prenatal caffeine.
Topics: Animals; Behavior, Animal; Caffeine; Female; Humans; Mice; Nervous System; Pregnancy; Prenatal Expos | 1989 |
Teratogenicity of caffeine; a review.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Coffee; Female; Humans; Infant, Newborn; Pregnancy; | 1989 |
Acute and chronic toxicity of caffeine: a review.
Topics: Animals; Biotransformation; Caffeine; Central Nervous System Stimulants; Female; Humans; Intestinal | 1986 |
Psychophysiological aspects of caffeine consumption.
Topics: Caffeine; Cardiovascular System; Female; Humans; Pregnancy; Psychomotor Performance; Sleep; Stimulat | 1988 |
Effects of caffeine consumption on pregnancy outcome. A review.
Topics: Animals; Caffeine; Female; Humans; Pregnancy; Pregnancy Outcome; Pregnancy, Animal | 1988 |
Reproductive and teratological risks of caffeine.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Female; Humans; Pregnancy | 1988 |
Caffeine and health.
Topics: Adult; Caffeine; Child; Female; Humans; Pregnancy; Substance-Related Disorders | 1987 |
Caffeine consumption and the risk of reproductive hazards.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Caffeine; Female; Humans; Infant, Low Birth Weig | 1988 |
What do we know about the risks of caffeine consumption in pregnancy?
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Caffeine; Female; Humans; Infant, Low Birth Weig | 1987 |
Caffeine: a toxicological overview.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Carbonated Beverages; Central Nervous System; Choles | 1986 |
[Brain dysfunction induced by maternal factors].
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Anticonvulsants; Brain; Brain Disease | 1985 |
Caffeine and human reproduction.
Topics: Caffeine; Female; Fetus; Humans; Pregnancy; Reproduction; Teratogens | 1985 |
Polygenic factors controlling drug response.
Topics: Adult; Animals; Antipyrine; Caffeine; Dicumarol; Environment; Ethanol; Female; Genetic Variation; Ha | 1974 |
Drug excretion in breast milk.
Topics: Anti-Bacterial Agents; Barbiturates; Biological Transport, Active; Breast; Breast Feeding; Caffeine; | 1974 |
[Current methods of drug therapy of a threatened premature labor (review of literature)].
Topics: Adult; Bicarbonates; Bromine; Caffeine; Ephedrine; Female; Humans; Muscle Contraction; Obstetric Lab | 1968 |
[Effect of drugs, ingested by the mother during pregnancy, on the fetus].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Caffeine; Female; Humans; Meclizine; Pregnancy; | 1969 |
Propoxyphene hydrochloride. A critical review.
Topics: Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Female; Headac | 1970 |
Alcohol: another intoxicating instalment.
Topics: Alcohol Oxidoreductases; Animals; Barbiturates; Caffeine; Drug Incompatibility; Ethanol; Fatty Liver | 1970 |
37 trials available for caffeine and Pregnancy
| Article | Year |
|---|---|
Preconception caffeine metabolites, caffeinated beverage intake, and fecundability.
Topics: Adolescent; Adult; Caffeine; Carbonated Beverages; Coffee; Female; Fertility; Humans; Pregnancy; The | 2022 |
Five-year outcomes of premature infants randomized to high or standard loading dose caffeine.
Topics: Caffeine; Child; Female; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Dise | 2022 |
Caffeine to prevent intermittent hypoxaemia in late preterm infants: randomised controlled dosage trial.
Topics: Adult; Caffeine; Citrates; Double-Blind Method; Female; Humans; Hypoxia; Infant; Infant, Newborn; In | 2023 |
Respiratory Outcome of Delivery Room Caffeine in Preterm Neonates-A Pilot, Randomized, Controlled Trial.
Topics: Caffeine; Delivery Rooms; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Pregn | 2023 |
Occipital Nerve Block Compared With Acetaminophen and Caffeine for Headache Treatment in Pregnancy: A Randomized Controlled Trial.
Topics: Acetaminophen; Anesthetics, Local; Caffeine; Female; Headache; Humans; Infant, Newborn; Nerve Block; | 2023 |
Caffeine administered to pregnant sows improves piglet vitality, gas exchange and body weight gain.
Topics: Animal Feed; Animals; Animals, Newborn; Caffeine; Central Nervous System Stimulants; Diet; Female; P | 2019 |
A novel semen supplement (SuinFort) improves sow fertility after artificial insemination.
Topics: Animals; Caffeine; Cryopreservation; Drug Therapy, Combination; Female; Fertility Agents, Female; In | 2019 |
(Rad 8)Caffeine prophylaxis to improve intermittent hypoxaemia in infants born late preterm: a randomised controlled dosage trial (Latte Dosage Trial).
Topics: Apnea; Caffeine; Female; Humans; Hypoxia; Infant; Infant, Newborn; Infant, Premature; New Zealand; P | 2020 |
Could aspartame exacerbate caffeine effects on renal maturation in rat's offspring? A biochemical and histological study.
Topics: Animals; Antioxidants; Aspartame; Caffeine; Female; Humans; Kidney; Maternal Exposure; Pregnancy; Ra | 2021 |
Study protocol: treatment with caffeine of the very preterm infant in the delivery room: a feasibility study.
Topics: Caffeine; Delivery Rooms; Feasibility Studies; Female; Humans; Infant; Infant, Newborn; Infant, Prem | 2020 |
Maternal caffeine administration to ewes does not affect perinatal lamb survival.
Topics: Administration, Oral; Animals; Animals, Newborn; Caffeine; Central Nervous System Stimulants; Dystoc | 2021 |
Oral caffeine administered during late gestation increases gestation length and piglet temperature in naturally farrowing sows.
Topics: Administration, Oral; Animals; Animals, Newborn; Birth Weight; Body Temperature; Caffeine; Drug Admi | 2018 |
Blood pressure and endothelial function in healthy, pregnant women after acute and daily consumption of flavanol-rich chocolate: a pilot, randomized controlled trial.
Topics: Adolescent; Adult; Biomarkers; Blood Pressure; Cacao; Caffeine; Candy; Catechin; Double-Blind Method | 2013 |
Pregnancy-induced changes in the pharmacokinetics of caffeine and its metabolites.
Topics: Adult; Caffeine; Cytochrome P-450 CYP1A2; Female; Humans; Pregnancy; Pregnancy Trimesters; Theobromi | 2016 |
[Clinical effectiveness of different doses of caffeine for primary apnea in preterm infants].
Topics: Apnea; Birth Weight; Caffeine; Citrates; Female; Gestational Age; Humans; Infant, Newborn; Infant, P | 2016 |
Triggers for Preeclampsia Onset: a Case-Crossover Study.
Topics: Acute Disease; Adolescent; Adult; Age Distribution; Alcohol Drinking; Caffeine; Central Nervous Syst | 2016 |
Acute caffeine ingestion and glucose tolerance in women with or without gestational diabetes mellitus.
Topics: Adult; Blood Glucose; C-Peptide; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Di | 2009 |
Foetal response to maternal coffee intake: role of habitual versus non-habitual caffeine consumption.
Topics: Adult; Caffeine; Coffee; Female; Fetal Movement; Fetus; Heart Rate, Fetal; Humans; Pregnancy; Sleep; | 2010 |
The effects of maternal caffeine and chocolate intake on fetal heart rate.
Topics: Adult; Cacao; Caffeine; Candy; Cardiotocography; Central Nervous System Stimulants; Coffee; Female; | 2012 |
Effects of caffeine on sperm characteristics after thawing and inflammatory response in the uterus after artificial insemination with frozen-thawed boar semen.
Topics: Animals; Caffeine; Female; Fertility; Freezing; Inflammation; Insemination, Artificial; Male; Pregna | 2013 |
Effect of reducing caffeine intake on birth weight and length of gestation: randomised controlled trial.
Topics: Adult; Birth Weight; Caffeine; Coffee; Double-Blind Method; Female; Gestational Age; Humans; Materna | 2007 |
Maternal caffeine consumption and risk of cardiovascular malformations.
Topics: Adolescent; Adult; Caffeine; Cardiovascular Abnormalities; Case-Control Studies; Central Nervous Sys | 2007 |
Caffeine as an analgesic adjuvant.
Topics: Acetaminophen; Adjuvants, Pharmaceutic; Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Dou | 1984 |
A double-blind randomized study of an aspirin/caffeine combination versus acetaminophen/aspirin combination versus acetaminophen versus placebo in patients with moderate to severe post-partum pain.
Topics: Acetaminophen; Adolescent; Adult; Aspirin; Caffeine; Double-Blind Method; Drug Combinations; Drug Ev | 1984 |
Selected birth defects in relation to caffeine-containing beverages.
Topics: Abnormalities, Drug-Induced; Beverages; Caffeine; Cleft Lip; Cleft Palate; Clinical Trials as Topic; | 1982 |
Regulatory aspects of teratology: role of the Food and Drug Administration.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Clinical Trials as Topic; Congenital Abnormalities; | 1982 |
Caffeine and fetal growth.
Topics: Birth Weight; Caffeine; Chromatography, Gas; Embryonic and Fetal Development; Female; Gestational Ag | 1997 |
North American survey of the management of dural puncture occurring during labour epidural analgesia.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Blood Patch, Epidural; Caffeine; Canada; Central | 1998 |
Effects of discontinuing coffee intake on iron deficient Guatemalan toddlers' cognitive development and sleep.
Topics: Anemia, Iron-Deficiency; Caffeine; Coffee; Cognition; Female; Guatemala; Hemoglobins; Humans; Infant | 1999 |
Aspirin and aspirin-caffeine in postpartum pain relief.
Topics: Adolescent; Adult; Aspirin; Caffeine; Clinical Trials as Topic; Double-Blind Method; Drug Combinatio | 1978 |
Acetaminophen extra strength capsules versus propoxphene compound-65 versus placebo: a double-blind study of effectiveness and safety.
Topics: Acetaminophen; Adolescent; Adult; Aspirin; Caffeine; Capsules; Clinical Trials as Topic; Dextropropo | 1975 |
Are caffeinated beverages risk factors for delayed conception?
Topics: Beverages; Caffeine; Carbonated Beverages; Evaluation Studies as Topic; Female; Fertilization; Human | 1990 |
Effects of oral caffeine on postdural puncture headache. A double-blind, placebo-controlled trial.
Topics: Administration, Oral; Adult; Benzoates; Benzoic Acid; Caffeine; Cerebrovascular Circulation; Double- | 1990 |
Effects of regular and decaffeinated coffee on fetal breathing and heart rate.
Topics: Blood Glucose; Blood Pressure; Caffeine; Catecholamines; Coffee; Female; Fetal Monitoring; Fetal Mov | 1989 |
The effect of antismoking intervention during pregnancy: an assessment of interactions with maternal characteristics.
Topics: Adolescent; Adult; Alcohol Drinking; Birth Weight; Caffeine; Educational Status; Female; Health Prom | 1985 |
Evaluation of propoxyphene napsylate compound in post partum uterine cramping.
Topics: Administration, Oral; Aspirin; Caffeine; Clinical Trials as Topic; Dextropropoxyphene; Female; Human | 1974 |
Propoxyphene hydrochloride. A critical review.
Topics: Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Female; Headac | 1970 |
891 other studies available for caffeine and Pregnancy
| Article | Year |
|---|---|
Experimental study of pre- and postnatal caffeine exposure and its observable effects on selected neurotransmitters and behavioural attributes at puberty : Caffeine exposure and its observable effects on selected neurotranmitters and behaviour.
Topics: Animals; Brain; Caffeine; Central Nervous System Stimulants; Female; Mice; Neurotransmitter Agents; | 2021 |
H19/let-7 axis mediates caffeine exposure during pregnancy induced adrenal dysfunction and its multi-generation inheritance.
Topics: Animals; Caffeine; Corticosterone; Female; Fetal Growth Retardation; Male; Pregnancy; Prenatal Expos | 2021 |
Qualitative LC-Q-TOF Analysis of Umbilical Cord Tissue via Data-Dependent Acquisition as an Indicator of In Utero Exposure to Toxic Adulterating Substances.
Topics: Analgesics, Opioid; Caffeine; Cocaine; Diphenhydramine; Drug Contamination; Female; Humans; Levamiso | 2022 |
Maternal caffeine intake and DNA methylation in newborn cord blood.
Topics: Adult; Caffeine; DNA Methylation; Epigenesis, Genetic; Female; Fetal Blood; Gestational Age; Humans; | 2022 |
Assessment of Caffeine Consumption and Maternal Cardiometabolic Pregnancy Complications.
Topics: Adult; Beverages; Caffeine; Cardiometabolic Risk Factors; Cohort Studies; Diabetes, Gestational; Fem | 2021 |
Prenatal smoking, alcohol and caffeine exposure and maternal-reported attention deficit hyperactivity disorder symptoms in childhood: triangulation of evidence using negative control and polygenic risk score analyses.
Topics: Attention Deficit Disorder with Hyperactivity; Caffeine; Cohort Studies; Female; Humans; Longitudina | 2022 |
Caffeine Exposure Causes Immune Dysfunction and Intrauterine Growth Restriction Retardation in Rats.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Female; Feta | 2022 |
Differential expression of placental 11β-HSD2 induced by high maternal glucocorticoid exposure mediates sex differences in placental and fetal development.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; 11-beta-Hydroxysteroid Dehydrogenases; Animals; Caffein | 2022 |
Total 25(OH)D Concentration Moderates the Association between Caffeine Consumption and the Alkaline Phosphatase Level in Pregnant Women.
Topics: Adult; Alkaline Phosphatase; Caffeine; Cross-Sectional Studies; Female; Humans; Pregnancy; Pregnant | 2022 |
Prenatal caffeine exposure induced renal developmental toxicity and transgenerational effect in rat offspring.
Topics: Animals; Caffeine; Female; Fetus; Glucocorticoids; Humans; Kidney Diseases; Pregnancy; Prenatal Expo | 2022 |
Intrauterine programming of cartilaginous 11β-HSD2 induced by corticosterone and caffeine mediated susceptibility to adult osteoarthritis.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aggrecans; Animals; Caffeine; Cartilage; Corticosterone | 2022 |
Effect of Nitric Oxide Synthase Inhibitor on the Learning and Spatial Memory in Rats Subjected to Long-Term Perinatal Administration of Caffeine.
Topics: Animals; Caffeine; Enzyme Inhibitors; Female; Maze Learning; Nitric Oxide; Nitric Oxide Synthase Typ | 2022 |
Association between maternal caffeine intake during pregnancy and child development at 6 and 12 months: The Japan Environment and Children's Study.
Topics: Caffeine; Child; Child Development; Cohort Studies; Female; Humans; Infant; Japan; Pregnancy; Prospe | 2022 |
Preconception vitamin D and miscarriage in a prospective cohort study.
Topics: Abortion, Spontaneous; Adult; Caffeine; Child; Female; Humans; Pregnancy; Prospective Studies; Time- | 2022 |
Behavioral, genetic and biochemical changes in the brain of the offspring of female mice treated with caffeine during pregnancy and lactation.
Topics: Animals; Brain; Caffeine; Female; Humans; Lactation; Male; Mice; Pregnancy; Prenatal Exposure Delaye | 2022 |
The upregulation of glutamate decarboxylase 67 against hippocampal excitability damage in male fetal rats by prenatal caffeine exposure.
Topics: Adenylyl Cyclases; Animals; Brain-Derived Neurotrophic Factor; Caffeine; Colforsin; Female; gamma-Am | 2022 |
In Utero Exposure to Caffeine and Acetaminophen, the Gut Microbiome, and Neurodevelopmental Outcomes: A Prospective Birth Cohort Study.
Topics: Acetaminophen; Bacteria; Birth Cohort; Caffeine; Cohort Studies; Female; Gastrointestinal Microbiome | 2022 |
Prospectively assessed perceived stress associated with early pregnancy losses among women with history of pregnancy loss.
Topics: Abortion, Spontaneous; Biomarkers; Caffeine; Child; Female; Humans; Nausea; Pregnancy; Stress, Psych | 2022 |
The caffeine consumption among Turkish pregnant women.
Topics: Birth Weight; Caffeine; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Pregnancy; Pregna | 2022 |
2022 Taiwan Guidelines for Acute Treatment of Migraine.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Caffeine; Calcitonin G | 2022 |
Association of Maternal Caffeine Consumption During Pregnancy With Child Growth.
Topics: Body Mass Index; Caffeine; Child; Child, Preschool; Cohort Studies; Female; Humans; Male; Obesity; P | 2022 |
Prenatal Caffeine Exposure Is Linked to Elevated Sugar Intake and BMI, Altered Reward Sensitivity, and Aberrant Insular Thickness in Adolescents: An ABCD Investigation.
Topics: Adolescent; Body Mass Index; Caffeine; Child; Female; Humans; Magnetic Resonance Imaging; Male; Preg | 2022 |
Is it caffeine? Coffee consumption and future risk of type 2 diabetes among women with a history of gestational diabetes.
Topics: Caffeine; Coffee; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Humans; Pregnancy; Prosp | 2022 |
Early-life fecal metabolomics of food allergy.
Topics: Allergens; Caffeine; Child; Child, Preschool; Female; Food Hypersensitivity; Humans; Infant; Metabol | 2023 |
Early-life fecal metabolomics of food allergy.
Topics: Allergens; Caffeine; Child; Child, Preschool; Female; Food Hypersensitivity; Humans; Infant; Metabol | 2023 |
Early-life fecal metabolomics of food allergy.
Topics: Allergens; Caffeine; Child; Child, Preschool; Female; Food Hypersensitivity; Humans; Infant; Metabol | 2023 |
Early-life fecal metabolomics of food allergy.
Topics: Allergens; Caffeine; Child; Child, Preschool; Female; Food Hypersensitivity; Humans; Infant; Metabol | 2023 |
Pre-pregnancy migraine diagnosis, medication use, and spontaneous abortion: a prospective cohort study.
Topics: Abortion, Spontaneous; Caffeine; Female; Humans; Migraine Disorders; Pregnancy; Proportional Hazards | 2022 |
Caffeine Intake throughout Pregnancy, and Factors Associated with Non-Compliance with Recommendations: A Cohort Study.
Topics: Caffeine; Coffee; Cohort Studies; Diet, Mediterranean; Female; Humans; Pregnancy; Pregnancy Outcome | 2022 |
Maternal dietary caffeine consumption and risk of birth defects in the National Birth Defects Prevention Study, 1997-2011.
Topics: Caffeine; Case-Control Studies; Child; Craniosynostoses; Diet; Female; Humans; Mothers; Pregnancy | 2023 |
Associations between health behaviours, fertility and reproductive outcomes: triangulation of evidence in the Norwegian Mother, Father and Child Cohort Study (MoBa).
Topics: Caffeine; Child; Cohort Studies; Fathers; Female; Fertility; Health Behavior; Humans; Male; Mothers; | 2023 |
Genotoxic effects of caffeine in female mice exposed during pregnancy and lactation period and their offspring.
Topics: Animals; Caffeine; Comet Assay; DNA Damage; Female; Lactation; Male; Mice; Micronucleus Tests; Pregn | 2023 |
Use of Physiologically Based Pharmacokinetic Modeling for Hepatically Cleared Drugs in Pregnancy: Regulatory Perspective.
Topics: Acetaminophen; Benzodiazepines; Caffeine; Clindamycin; Female; Glucuronosyltransferase; Humans; Preg | 2023 |
Maternal consumption of caffeine and second-hand tobacco smoke as risk factors for the development of oral clefts.
Topics: Caffeine; Case-Control Studies; Child; Child, Preschool; Cleft Lip; Cleft Palate; Female; Folic Acid | 2023 |
Variables related to bronchopulmonary dysplasia severity: a Six-Year retrospective study.
Topics: Bronchopulmonary Dysplasia; Caffeine; Female; Gestational Age; Humans; Infant, Newborn; Intensive Ca | 2023 |
Assessment of caffeine intake in groups of pregnant and breastfeeding women: A cross-sectional analysis.
Topics: Breast Feeding; Caffeine; Coffee; Cross-Sectional Studies; Female; Food; Humans; Pregnancy | 2023 |
Cathepsin D mediates prenatal caffeine exposure-caused NAFLD susceptibility in male rat offspring by regulating autophagy.
Topics: Animals; Autophagy; Caffeine; Cathepsin D; Corticosterone; Female; Humans; Male; MicroRNAs; Non-alco | 2023 |
Microbiota-indole 3-propionic acid-brain axis mediates abnormal synaptic pruning of hippocampal microglia and susceptibility to ASD in IUGR offspring.
Topics: Animals; Autism Spectrum Disorder; Brain; Caffeine; Female; Fetal Growth Retardation; Gastrointestin | 2023 |
Variations in preterm stabilisation practices and caffeine therapy between two European tertiary level neonatal units.
Topics: Bronchopulmonary Dysplasia; Caffeine; Female; Gestational Age; Humans; Infant; Infant, Newborn; Infa | 2020 |
The effect of prenatal and postnatal caffeine exposure on pentylentetrazole induced seizures in the non-epileptic and epileptic offsprings.
Topics: Animals; Brain; Caffeine; Calcium Channels, T-Type; Epilepsy, Absence; Female; Male; Pentylenetetraz | 2019 |
Serum metabolic profile characteristics of offspring rats before and after birth caused by prenatal caffeine exposure.
Topics: Amino Acids; Animals; Caffeine; Female; Fetal Growth Retardation; Lipid Metabolism; Male; Maternal-F | 2019 |
Approximation of bias and mean-squared error in two-sample Mendelian randomization analyses.
Topics: Bias; Biometry; Birth Weight; Caffeine; Causality; Computer Simulation; Female; Fetal Macrosomia; Ge | 2020 |
Effects of ethanol, nicotine and caffeine gestational exposure of female rats on lung and brain tissues in fetuses: morphological and biological study.
Topics: Animals; Brain; Caffeine; Cross-Sectional Studies; Ethanol; Female; Fetus; Lung; Male; Nicotine; Pre | 2019 |
Caffeine and adenosine A
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Animals; Attention Deficit Disord | 2020 |
The effects of caffeine and bisphenol A singularly or in combination on cultured mouse embryos and yolk sac placenta.
Topics: Animals; Apoptosis; Benzhydryl Compounds; Caffeine; Embryo, Mammalian; Embryonic Development; Female | 2020 |
Programming changes in GLUT1 mediated the accumulation of AGEs and matrix degradation in the articular cartilage of female adult rats after prenatal caffeine exposure.
Topics: Animals; Animals, Newborn; Caffeine; Cartilage, Articular; Female; Glucose Transporter Type 1; Glyca | 2020 |
Long-term neurological effects of neonatal caffeine treatment in a rabbit model of preterm birth.
Topics: Animals; Animals, Newborn; Astrocytes; Behavior, Animal; Brain; Caffeine; Central Nervous System Sti | 2020 |
Prenatal caffeine exposure induces down-regulation of the protein kinase A/ryanodine receptor/large-conductance Ca2+-activated K+ pathway in the cerebral arteries of old offspring rats.
Topics: Animals; Caffeine; Calcium; Cerebral Arteries; Cyclic AMP-Dependent Protein Kinases; Down-Regulation | 2020 |
Subchondral bone dysplasia mediates susceptibility to osteoarthritis in female adult offspring rats induced by prenatal caffeine exposure.
Topics: Age Factors; Animals; Bone Diseases, Developmental; Caffeine; Cartilage, Articular; Cell Differentia | 2020 |
Caffeine supplementation at birth, but not 8 to 12 h post-birth, increased 24 h pre-weaning mortality in piglets.
Topics: Animals; Animals, Newborn; Birth Weight; Caffeine; Dietary Supplements; Female; Humans; Parturition; | 2020 |
Associations of maternal caffeine intake during pregnancy with abdominal and liver fat deposition in childhood.
Topics: Abdominal Fat; Adipose Tissue; Adult; Caffeine; Child; Cohort Studies; Female; Humans; Liver; Male; | 2020 |
Use of stimulants, over-the-counter and prescription drugs among Danish pregnant women.
Topics: Adult; Alcohol Drinking; Caffeine; Denmark; Female; Humans; Illicit Drugs; Nonprescription Drugs; Pr | 2020 |
Maternal coffee intake and the risk of bleeding in early pregnancy: a cross-sectional analysis.
Topics: Adult; Body Mass Index; Caffeine; Coffee; Cross-Sectional Studies; Female; Humans; Logistic Models; | 2020 |
Caffeine use during pregnancy: prevalence of use and newborn consequences in a cohort of French pregnant women.
Topics: Caffeine; Cohort Studies; Female; France; Humans; Infant, Newborn; Pregnancy; Prenatal Exposure Dela | 2021 |
GR/HDAC2/TGFβR1 pathway contributes to prenatal caffeine induced-osteoarthritis susceptibility in male adult offspring rats.
Topics: Animals; Caffeine; Disease Susceptibility; Female; Histone Deacetylase 2; Male; Osteoarthritis; Preg | 2020 |
Caffeine content in newborn hair correlates with maternal dietary intake.
Topics: Caffeine; Child; Coffee; Diet; Eating; Female; Humans; Infant, Newborn; Pregnancy; Pregnancy Trimest | 2021 |
Caffeine, alcohol, khat, and tobacco use during pregnancy in Butajira, South Central Ethiopia.
Topics: Adolescent; Adult; Alcohol Drinking; Caffeine; Catha; Ethiopia; Female; Humans; Logistic Models; Mas | 2020 |
Maternal caffeine intake during pregnancy and child neurodevelopment up to eight years of age-Results from the Norwegian Mother, Father and Child Cohort Study.
Topics: Caffeine; Child; Child Development; Cohort Studies; Fathers; Female; Humans; Language; Male; Mothers | 2021 |
Changes in Behavior with Increasing Pregnancy Attempt Time: A Prospective Cohort Study.
Topics: Adult; Alcohol Drinking; Caffeine; Female; Fertility; Humans; Marijuana Smoking; Middle Aged; North | 2020 |
Articular damages in multi-generational female offspring due to prenatal caffeine exposure correlates with H3K9 deacetylation of TGFβ signaling pathway.
Topics: Animals; Caffeine; Cartilage Diseases; Cartilage, Articular; Central Nervous System Stimulants; Chon | 2020 |
The low-expression programming of 11β-HSD2 mediates osteoporosis susceptibility induced by prenatal caffeine exposure in male offspring rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; 11-beta-Hydroxysteroid Dehydrogenases; Animals; Caffein | 2020 |
Contribution of estrogen to the pregnancy-induced increase in cardiac automaticity.
Topics: Action Potentials; Animals; Caffeine; Calcium Channels, L-Type; Estradiol; Estrogen Receptor alpha; | 2020 |
Recalled maternal lifestyle behaviors associated with anti-müllerian hormone of adult female offspring.
Topics: Adolescent; Adult; Alcohol Drinking; Anti-Mullerian Hormone; Caffeine; Female; Humans; Life Style; M | 2020 |
The dosage-dependent prenatal caffeine exposure adversely affects levels of integrin αVβ3 and MMP-9 in a rat model of embryo implantation.
Topics: Animals; Caffeine; Embryo Implantation; Female; Integrin alphaVbeta3; Matrix Metalloproteinase 9; Pr | 2020 |
Effects of gestational and breastfeeding caffeine exposure in adenosine A1 agonist-induced antinociception of infant rats.
Topics: Adenosine; Animals; Caffeine; Female; Lactation; Pregnancy; Rats; Rats, Wistar; Receptor, Adenosine | 2020 |
The protective role of melatonin against the effects of different doses of caffeine on the fetus.
Topics: Animals; Antioxidants; Biomarkers; Bone and Bones; Caffeine; Female; Fetus; Inflammation; Liver; Mal | 2020 |
The effects of caffeine on ovarian tissue in rats.
Topics: Animals; Caffeine; Female; Maternal-Fetal Exchange; Organ Size; Ovary; Pregnancy; Rats, Wistar | 2021 |
Caffeine editorial.
Topics: Caffeine; Humans; Pregnancy | 2020 |
Addition of caffeine to equine thawed sperm increases motility and decreases nitrite concentration.
Topics: Animals; Caffeine; Cryopreservation; Female; Horses; Humans; Insemination, Artificial; Male; Nitrite | 2021 |
Association between self-reported caffeine intake during pregnancy and social responsiveness scores in childhood: The EARLI and HOME studies.
Topics: Adult; Autism Spectrum Disorder; Body Mass Index; Caffeine; Child; Child, Preschool; Databases, Fact | 2021 |
Maternal caffeine intake during pregnancy and risk of food allergy in young Japanese children.
Topics: Caffeine; Child; Dermatitis, Atopic; Female; Food Hypersensitivity; Humans; Japan; Pregnancy; Survey | 2021 |
Hypertensive Disorders of Pregnancy in Relation to Coffee and Tea Consumption: The Japan Environment and Children's Study.
Topics: Adult; Caffeine; Coffee; Drinking Behavior; Female; Humans; Hypertension, Pregnancy-Induced; Pregnan | 2021 |
Careful data extraction in meta-analysis: the case of maternal caffeine intake during pregnancy and low-birth weight, childhood overweight, and obesity.
Topics: Birth Weight; Caffeine; Child; Eating; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Pe | 2021 |
Caffeine exposure in utero is associated with structural brain alterations and deleterious neurocognitive outcomes in 9-10 year old children.
Topics: Brain; Caffeine; Central Nervous System Stimulants; Child; Developmental Disabilities; Female; Human | 2021 |
Supplementing pregnant Merino ewes with caffeine to improve neonatal lamb thermoregulation and viability.
Topics: Animal Feed; Animals; Animals, Newborn; Body Temperature Regulation; Caffeine; Diet; Dietary Supplem | 2021 |
Prenatal caffeine exposure caused H-type blood vessel-related long bone dysplasia via miR375/CTGF signaling.
Topics: Animals; Bone Development; Bone Diseases, Developmental; Caffeine; Cells, Cultured; Chondrocytes; Co | 2021 |
Association Between Maternal Caffeine Consumption and Metabolism and Neonatal Anthropometry: A Secondary Analysis of the NICHD Fetal Growth Studies-Singletons.
Topics: Adult; Anthropometry; Biomarkers; Birth Weight; Caffeine; Female; Fetal Development; Follow-Up Studi | 2021 |
Intrauterine endogenous high glucocorticoids program ovarian dysfunction in female offspring secondary to prenatal caffeine exposure.
Topics: Animals; Caffeine; Corticosterone; Female; Glucocorticoids; Pregnancy; Prenatal Exposure Delayed Eff | 2021 |
Selected morphological and mechanical features of the femur of pregnant rats after exposure to caffeine applied at various temperatures Caffeine in the nutrition of pregnant rats.
Topics: Animals; Bone and Bones; Caffeine; Female; Femur; Pregnancy; Rats; Rats, Wistar; Temperature | 2021 |
Health behaviours in 131,182 UK women planning pregnancy.
Topics: Adult; Alcohol Drinking; Caffeine; Cohort Studies; Dietary Supplements; Female; Folic Acid; Fruit; H | 2021 |
Prenatal caffeine exposure: association with neurodevelopmental outcomes in 9- to 11-year-old children.
Topics: Adolescent; Brain; Caffeine; Child; Child Development; Cognition; Female; Humans; Male; Pregnancy; P | 2022 |
Interaction between maternal caffeine intake during pregnancy and CYP1A2 C164A polymorphism affects infant birth size in the Hokkaido study.
Topics: Alcohol Drinking; Birth Weight; Caffeine; Cohort Studies; Cytochrome P-450 CYP1A2; Female; Genotype; | 2017 |
Caffeine ameliorates hyperoxia-induced lung injury by protecting GCH1 function in neonatal rat pups.
Topics: Animals; Animals, Newborn; Caffeine; Cyclic AMP; Female; GTP Cyclohydrolase; Hyperoxia; Lung Injury; | 2017 |
Maternal Smoking during Pregnancy Is Associated with Offspring Hypodontia.
Topics: Adolescent; Adult; Alcohol Drinking; Anodontia; Caffeine; Case-Control Studies; Female; Gestational | 2017 |
The perinatal effects of maternal caffeine intake on fetal and neonatal brain levels of testosterone, estradiol, and dihydrotestosterone in rats.
Topics: Animals; Animals, Newborn; Caffeine; Dihydrotestosterone; Estradiol; Female; Fetus; Frontal Lobe; Hy | 2017 |
Early-life exposure to caffeine affects the construction and activity of cortical networks in mice.
Topics: Animals; Animals, Newborn; Caffeine; Central Nervous System Stimulants; Cerebral Cortex; Dendrites; | 2017 |
Prenatal caffeine exposure induced high susceptibility to metabolic syndrome in adult female offspring rats and its underlying mechanisms.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Blood Glucose; Caffeine; Central Nervous Syste | 2017 |
Maternal Smoking, Alcohol, and Caffeine Exposures and Risk of Hypospadias.
Topics: Adult; Alcohol Drinking; Caffeine; Case-Control Studies; Cigarette Smoking; Ethanol; Female; Humans; | 2017 |
Caffeine supplementation of ewes during lambing may increase lamb survival.
Topics: Animals; Australia; Caffeine; Female; Male; Parturition; Pregnancy; Random Allocation; Sheep | 2018 |
Maternal Caffeine Consumption during Pregnancy and Behavioral Disorders in 11-Year-Old Offspring: A Danish National Birth Cohort Study.
Topics: Adolescent; Adult; Caffeine; Child; Child Behavior Disorders; Cohort Studies; Denmark; Female; Human | 2017 |
In vivo assessment of hair cell damage and developmental toxicity caused by gestational caffeine exposure using zebrafish (Danio rerio) models.
Topics: Animals; Apoptosis; Caffeine; Embryo, Nonmammalian; Female; Hair Cells, Auditory; Mitochondria; Preg | 2017 |
The association between pre-treatment maternal alcohol and caffeine intake and outcomes of assisted reproduction in a prospectively followed cohort.
Topics: Adult; Alcohol Drinking; Caffeine; Cohort Studies; Female; Humans; Infertility, Female; Pregnancy; P | 2017 |
Effect of caffeine on superior mesenteric artery blood flow velocities in preterm neonates.
Topics: Blood Flow Velocity; Caffeine; Citrates; Female; Gestational Age; Hemodynamics; Humans; Infant, Newb | 2019 |
A Physiologically Based Pharmacokinetic Model for Pregnant Women to Predict the Pharmacokinetics of Drugs Metabolized Via Several Enzymatic Pathways.
Topics: Caffeine; Cytochrome P-450 Enzyme System; Diazepam; Female; Granisetron; Humans; Metoprolol; Metroni | 2018 |
Association between preconception maternal beverage intake and in vitro fertilization outcomes.
Topics: Adult; Blastocyst; Caffeine; Carbonated Beverages; Chi-Square Distribution; Coffee; Female; Fertilit | 2017 |
Effects of prenatal caffeine exposure on glucose homeostasis of adult offspring rats.
Topics: Animals; Blood Glucose; Caffeine; Diabetes Mellitus, Type 2; Female; Fetal Growth Retardation; Gene | 2017 |
Prenatal caffeine ingestion increases susceptibility to pulmonary inflammation in adult female rat offspring.
Topics: Animals; Caffeine; Cytokines; Female; Fetal Growth Retardation; Inflammation; Lung; Pregnancy; Prena | 2017 |
Maternal Glucocorticoid Elevation and Associated Fetal Thymocyte Apoptosis are Involved in Immune Disorders of Prenatal Caffeine Exposed Offspring Mice.
Topics: Animals; Apoptosis; Caffeine; Cell Count; Cytokines; Female; Fetus; Glucocorticoids; Maternal Exposu | 2017 |
Glucocorticoid mediates prenatal caffeine exposure-induced endochondral ossification retardation and its molecular mechanism in female fetal rats.
Topics: Animals; Caffeine; Cell Differentiation; Female; Fetal Growth Retardation; Fetus; Glucocorticoids; O | 2017 |
High-fat diet and chronic stress aggravate adrenal function abnormality induced by prenatal caffeine exposure in male offspring rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenal Glands; Animals; Caffeine; Corticosterone; Diet, High | 2017 |
Intermittent hypoxia alters dose dependent caffeine effects on renal prostanoids and receptors in neonatal rats.
Topics: Animals; Animals, Newborn; Aquaporins; Caffeine; Cell Hypoxia; Dose-Response Relationship, Drug; Fem | 2018 |
High expression of hippocampal glutamic acid decarboxylase 67 mediates hypersensitivity of the hypothalamic-pituitary-adrenal axis in response to prenatal caffeine exposure in rats.
Topics: Adrenocorticotropic Hormone; Animals; Caffeine; Cells, Cultured; Corticosterone; Female; gamma-Amino | 2018 |
Maintained MPF Level after Oocyte Vitrification Improves Embryonic Development after IVF, but not after Somatic Cell Nuclear Transfer.
Topics: Animals; Blastocyst; Caffeine; Embryonic Development; Female; Fertilization in Vitro; Leupeptins; Ma | 2017 |
Effect of oral progesterone and caffeine at the end of gestation on farrowing duration and piglet growth and survival.
Topics: Animal Husbandry; Animals; Caffeine; Female; Litter Size; Parturition; Pregnancy; Progesterone; Surv | 2018 |
Is dietary macronutrient composition during pregnancy associated with offspring birth weight? An observational study.
Topics: Adult; Alcohol Drinking; Birth Weight; Body Mass Index; Caffeine; Diet; Diet Records; Dietary Carboh | 2018 |
IGF1/MAPK/ERK signaling pathway-mediated programming alterations of adrenal cortex cell proliferation by prenatal caffeine exposure in male offspring rats.
Topics: Adrenal Cortex; Animals; Body Weight; Caffeine; Cell Proliferation; Cells, Cultured; Cellular Reprog | 2018 |
Cerebellar oxidative stress and fine motor impairment in adolescent rats exposed to hyperthermia-induced seizures is prevented by maternal caffeine intake during gestation and lactation.
Topics: 5'-Nucleotidase; Adenosine; Animals; Caffeine; Cerebellum; Female; Fever; Gait; Lactation; Mothers; | 2018 |
Topics: Caffeine; Coffee; Cohort Studies; Denmark; Female; Humans; Love; Pregnancy | 2018 |
Behavioral and neuroanatomical outcomes in a rat model of preterm hypoxic-ischemic brain Injury: Effects of caffeine and hypothermia.
Topics: Acoustic Stimulation; Animals; Animals, Newborn; Behavior, Animal; Brain; Caffeine; Central Nervous | 2018 |
Prevalence of xenobiotic substances in first-trimester blood samples from Danish pregnant women: a cross-sectional study.
Topics: Caffeine; Cross-Sectional Studies; Denmark; Female; Humans; Illicit Drugs; Nicotine; Nonprescription | 2018 |
Adherence to the Caffeine Intake Guideline during Pregnancy and Birth Outcomes: A Prospective Cohort Study.
Topics: Adult; Australia; Birth Weight; Caffeine; Female; Fetal Development; Follow-Up Studies; Humans; Infa | 2018 |
Maternal caffeine intake in pregnancy is inversely related to childhood peer problems in Japan: The Kyushu Okinawa Maternal and Child Health Study.
Topics: Adult; Caffeine; Child, Preschool; Drinking Behavior; Female; Humans; Japan; Male; Maternal Nutritio | 2019 |
Caffeine Augments Anesthesia Neurotoxicity in the Fetal Macaque Brain.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Brain; Caffeine; Cell Dea | 2018 |
Maternal caffeine intake during pregnancy and childhood growth and overweight: results from a large Norwegian prospective observational cohort study.
Topics: Caffeine; Child; Child Development; Child, Preschool; Cohort Studies; Diet Records; Eating; Female; | 2018 |
Association Between Serum Folate Levels and Caffeinated Beverage Consumption in Pregnant Women in Chiba: The Japan Environment and Children's Study.
Topics: Adult; Beverages; Caffeine; Diet Surveys; Female; Folic Acid; Humans; Japan; Pregnancy | 2018 |
Intrauterine programming mechanism for hypercholesterolemia in prenatal caffeine-exposed female adult rat offspring.
Topics: Animals; Caffeine; CCAAT-Enhancer-Binding Protein-alpha; Cholesterol, LDL; Epigenesis, Genetic; Fema | 2018 |
Influencing factors, underlying mechanism and interactions affecting hypercholesterolemia in adult offspring with caffeine exposure during pregnancy.
Topics: Animals; Apolipoproteins B; Caffeine; Cholesterol; Female; Gene Expression Regulation; Hydroxymethyl | 2018 |
Nonlinear effects of caffeine on the viability, synthesis and gene expression of chondrocytes from the offspring of rats treated during pregnancy.
Topics: Animals; Animals, Newborn; Caffeine; Cartilage, Articular; Cell Survival; Chondrocytes; Collagen; Fe | 2018 |
Prenatal caffeine ingestion induces long-term alterations in scavenger receptor class B type I expression and glucocorticoid synthesis in adult male offspring rat adrenals.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Caffeine; Cholesterol; Corticosterone; Female; | 2018 |
Prenatal caffeine exprosure increases adult female offspring rat's susceptibility to osteoarthritis via low-functional programming of cartilage IGF-1 with histone acetylation.
Topics: Acetylation; Aggrecans; Animals; Caffeine; Cartilage, Articular; Cells, Cultured; Central Nervous Sy | 2018 |
Caffeine consumption during early pregnancy impairs oviductal embryo transport, embryonic development and uterine receptivity in mice.
Topics: Animals; Caffeine; Embryo Implantation; Embryo, Mammalian; Fallopian Tubes; Female; Mice; Pregnancy; | 2018 |
Influence of Caffeine Consumption by Pregnant Rats on Behavior and Learning in Their Offspring.
Topics: Administration, Oral; Animals; Avoidance Learning; Caffeine; Female; Locomotion; Male; Maternal Expo | 2018 |
Phenylephrine, a common cold remedy active ingredient, suppresses uterine contractions through cAMP signalling.
Topics: Animals; Caffeine; Common Cold; Cyclic AMP; Estradiol; Female; Genitalia, Female; Humans; Intracellu | 2018 |
Maternal and Paternal Caffeine Intake and ART Outcomes in Couples Referring to an Italian Fertility Clinic: A Prospective Cohort.
Topics: Adult; Body Mass Index; Caffeine; Female; Fertilization in Vitro; Follow-Up Studies; Humans; Italy; | 2018 |
Prenatal caffeine damaged learning and memory in rat offspring mediated by ARs/PKA/CREB/BDNF pathway.
Topics: Animals; Brain-Derived Neurotrophic Factor; Caffeine; Cyclic AMP Response Element-Binding Protein; C | 2018 |
Intrauterine Programming of Glucocorticoid-Insulin-Like Growth Factor-1 Axis-Mediated Developmental Origin of Osteoporosis Susceptibility in Female Offspring Rats with Prenatal Caffeine Exposure.
Topics: Animals; Animals, Newborn; Caffeine; Cells, Cultured; Cellular Reprogramming; Central Nervous System | 2018 |
Associations of maternal caffeine intake with birth outcomes: results from the Lifeways Cross Generation Cohort Study.
Topics: Adult; Alcohol Drinking; Birth Weight; Caffeine; Cigarette Smoking; Coffee; Cohort Studies; Diet; Fe | 2018 |
Key Findings and Implications of a Recent Systematic Review of the Potential Adverse Effects of Caffeine Consumption in Healthy Adults, Pregnant Women, Adolescents, and Children.
Topics: Adolescent; Adult; Bone and Bones; Caffeine; Calcium; Canada; Cardiovascular System; Child; Eating; | 2018 |
Activation of local bone RAS by maternal excessive glucocorticoid participated in the fetal programing of adult osteopenia induced by prenatal caffeine exposure.
Topics: Animals; Bone and Bones; Bone Diseases, Metabolic; Bone Marrow Cells; Caffeine; Cell Differentiation | 2019 |
Consumption habits of pregnant women in the Jazan region, Saudi Arabia: a descriptive study.
Topics: Adolescent; Adult; Animals; Beverages; Caffeine; Diet; Dietary Supplements; Female; Folic Acid; Frui | 2018 |
Glucocorticoid-activation system mediated glucocorticoid-insulin-like growth factor 1 (GC-IGF1) axis programming alteration of adrenal dysfunction induced by prenatal caffeine exposure.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenal Gland Diseases; Adrenal Glands; Age Factors; Animals; | 2019 |
Association between Caffeine Consumption in Pregnancy and Low Birth Weight and Preterm Birth in the birth Cohort of Ribeirão Preto.
Topics: Adult; Brazil; Caffeine; Cohort Studies; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; | 2018 |
Hourly and daily intake patterns among U.S. caffeinated beverage consumers based on the National Health and Nutrition Examination Survey (NHANES, 2013-2016).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Beverages; Caffeine; Child; Child, Preschool; Diet Surve | 2019 |
Physiologically Based Pharmacokinetic/Pharmacodynamic Model for Caffeine Disposition in Pregnancy.
Topics: Abortion, Spontaneous; Caffeine; Cyclic AMP-Dependent Protein Kinases; Cytochrome P-450 CYP1A2; Dose | 2019 |
Prenatal caffeine exposure increases the susceptibility to non-alcoholic fatty liver disease in female offspring rats via activation of GR-C/EBPα-SIRT1 pathway.
Topics: Animals; Caffeine; CCAAT-Binding Factor; Dose-Response Relationship, Drug; Female; Non-alcoholic Fat | 2019 |
Inhibition of thymocyte autophagy-associated CD4
Topics: Animals; Asthma; Autophagy; Caffeine; CD4-Positive T-Lymphocytes; Central Nervous System Stimulants; | 2019 |
Caffeine exposure during pregnancy, small for gestational age birth and neonatal outcome - results from the Norwegian Mother and Child Cohort Study.
Topics: Adult; Birth Weight; Caffeine; Cohort Studies; Female; Gestational Age; Humans; Infant, Low Birth We | 2019 |
Caffeine programs hepatic SIRT1-related cholesterol synthesis and hypercholesterolemia via A2AR/cAMP/PKA pathway in adult male offspring rats.
Topics: Acetylation; Age Factors; Animals; Caffeine; Cell Line; Cholesterol; Cyclic AMP; Cyclic AMP-Dependen | 2019 |
Caffeine Intake During Pregnancy and Neonatal Anthropometric Parameters.
Topics: Adult; Anthropometry; Beverages; Caffeine; Coffee; Energy Drinks; Female; Fetal Development; Humans; | 2019 |
Post-thaw Addition of Caffeine and/or Pentoxifylline Affect Differently Motility of Horse and Donkey-Cryopreserved Spermatozoa.
Topics: Animals; Caffeine; Equidae; Female; Horses; Humans; Male; Pentoxifylline; Pregnancy; Sperm Motility; | 2019 |
Dose-dependent associations between prenatal caffeine consumption and small for gestational age, preterm birth, and reduced birthweight in the Japan Environment and Children's Study.
Topics: Adult; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Female; Humans | 2019 |
Antioxidative effects of caffeine in a hyperoxia-based rat model of bronchopulmonary dysplasia.
Topics: Animals; Animals, Newborn; Antioxidants; Bronchopulmonary Dysplasia; Caffeine; Disease Models, Anima | 2019 |
Maternal, but not paternal or grandparental, caffeine intake is associated with childhood obesity and adiposity: The Lifeways Cross-Generation Cohort Study.
Topics: Adiposity; Adult; Body Mass Index; Caffeine; Child; Child, Preschool; Coffee; Female; Humans; Male; | 2019 |
The GC-IGF1 axis-mediated testicular dysplasia caused by prenatal caffeine exposure.
Topics: Animals; Caffeine; Female; Glucocorticoids; Insulin-Like Growth Factor I; Leydig Cells; Male; Pregna | 2019 |
The Problem With Mechanistic Risk of Bias Assessments in Evidence Synthesis of Observational Studies and a Practical Alternative: Assessing the Impact of Specific Sources of Potential Bias.
Topics: Bias; Caffeine; Female; Humans; Meta-Analysis as Topic; Observational Studies as Topic; Pregnancy; P | 2019 |
Decreased H3K9ac level of KLF4 mediates podocyte developmental toxicity induced by prenatal caffeine exposure in male offspring rats.
Topics: Acetylation; Animals; Caffeine; Cells, Cultured; Central Nervous System Stimulants; Female; Gene Exp | 2019 |
Prenatal caffeine exposure induces liver developmental dysfunction in offspring rats.
Topics: Animals; Caffeine; Corticosterone; Female; Fetal Development; Fetal Growth Retardation; Gene Express | 2019 |
Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results from a large prospective observational cohort study.
Topics: Adult; Birth Weight; Caffeine; Cohort Studies; Diet; Female; Humans; Norway; Pregnancy; Premature Bi | 2013 |
The effects of different concentrations of cocoa in the chocolate intaken by the mother on fetal heart rate.
Topics: Adult; Cacao; Caffeine; Cardiotocography; Diet; Female; Fetal Movement; Gestational Age; Heart Rate, | 2013 |
Is caffeine consumption safe during pregnancy?
Topics: Abortion, Spontaneous; Beverages; Caffeine; Child Development; Female; Fertility; Humans; Infant; In | 2013 |
Caffeine is modestly associated with lower birth weight and fetal growth.
Topics: Birth Weight; Caffeine; Diet; Female; Humans; Pregnancy; Premature Birth | 2014 |
Consumption habits of pregnant women and implications for developmental biology: a survey of predominantly Hispanic women in California.
Topics: Adolescent; Adult; Animals; Benzhydryl Compounds; Beverages; Caffeine; California; Dietary Supplemen | 2013 |
Relationship between plasma total homocysteine level and dietary caffeine and vitamin B6 intakes in pregnant women.
Topics: Adult; Biomarkers; Caffeine; Cross-Sectional Studies; Diet; Female; Fetal Development; Homocysteine; | 2014 |
Risk of spina bifida and maternal cigarette, alcohol, and coffee use during the first month of pregnancy.
Topics: Adolescent; Adult; Alcohol Drinking; Caffeine; Case-Control Studies; Coffee; Female; Folic Acid; Hum | 2013 |
Influence of caffeine pretreatment on biphasic in vitro maturation of dog oocytes.
Topics: Animals; Caffeine; Dogs; Enzyme-Linked Immunosorbent Assay; Female; In Vitro Oocyte Maturation Techn | 2013 |
Cup of Joe: a brain development "no"?
Topics: Animals; Brain; Caffeine; Female; Fetus; Pregnancy; Purinergic P1 Receptor Antagonists | 2013 |
Adenosine receptor antagonists including caffeine alter fetal brain development in mice.
Topics: Aging; Animals; Animals, Newborn; Brain; Caffeine; Cell Movement; Cognition Disorders; Disease Susce | 2013 |
Amplification of steroid-mediated SP-B expression by physiological levels of caffeine.
Topics: Animals; Antigens, Surface; Bronchoalveolar Lavage Fluid; Caffeine; Cathepsin H; Dexamethasone; Fema | 2014 |
Intrauterine metabolic programming alteration increased susceptibility to non-alcoholic adult fatty liver disease in prenatal caffeine-exposed rat offspring.
Topics: Algorithms; Animals; Blood Glucose; Body Weight; Caffeine; Central Nervous System Stimulants; Fatty | 2014 |
Maternal caffeine consumption and small for gestational age births: results from a population-based case-control study.
Topics: Adolescent; Adult; Caffeine; Carbonated Beverages; Case-Control Studies; Central Nervous System Stim | 2014 |
The role of clomipramine in potentiating the teratogenic effects of caffeine in pregnant rats: a histopathological study.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Clomipramine; Dose-Response Relationship, Drug; Drug | 2013 |
Prenatal caffeine ingestion induces transgenerational neuroendocrine metabolic programming alteration in second generation rats.
Topics: Animals; Blood Glucose; Body Weight; Caffeine; Cholesterol, HDL; Cholesterol, LDL; Corticosterone; D | 2014 |
Higher coffee intake in pregnancy linked to prolonged gestation, and higher caffeine intake linked with babies being small for gestational age.
Topics: Birth Weight; Caffeine; Diet; Female; Humans; Pregnancy; Premature Birth | 2014 |
Maternal glucocorticoid elevation and associated blood metabonome changes might be involved in metabolic programming of intrauterine growth retardation in rats exposed to caffeine prenatally.
Topics: Animals; Caffeine; Corticosterone; Dose-Response Relationship, Drug; Drug Synergism; Female; Fetal G | 2014 |
The testis of the mice C57/BL6 offspring in adulthood have alterations due to maternal caffeine consumption.
Topics: Animals; Body Mass Index; Caffeine; Eating; Estradiol; Female; Follicle Stimulating Hormone; Leptin; | 2014 |
Embryonic caffeine exposure acts via A1 adenosine receptors to alter adult cardiac function and DNA methylation in mice.
Topics: Analysis of Variance; Animals; Caffeine; DNA Methylation; DNA Primers; Echocardiography; Female; Hea | 2014 |
Early caffeine therapy for prevention of bronchopulmonary dysplasia in preterm infants.
Topics: Bronchopulmonary Dysplasia; Caffeine; Central Nervous System Stimulants; Female; Humans; Infant, New | 2014 |
Tobacco smoking and its consequences on reproductive health: the impact of a lifestyle choices including cigarette smoke exposure on fertility and birth defects.
Topics: Adolescent; Adult; Alcohol Drinking; Caffeine; Causality; Cohort Studies; Comorbidity; Female; Ferti | 2013 |
Descriptive and risk factor analysis for choanal atresia: The National Birth Defects Prevention Study, 1997-2007.
Topics: Alcohol Drinking; Caffeine; Choanal Atresia; Diet; Female; Humans; Male; Pregnancy; Prenatal Nutriti | 2014 |
Excess caffeine exposure impairs eye development during chick embryogenesis.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Chick Embryo; Embryonic Development; Eye Prote | 2014 |
Prenatal caffeine ingestion induces aberrant DNA methylation and histone acetylation of steroidogenic factor 1 and inhibits fetal adrenal steroidogenesis.
Topics: Acetylation; Adrenal Glands; Animals; Anti-Inflammatory Agents; Caffeine; Central Nervous System Sti | 2014 |
Impact of daily high-dose caffeine exposure on developing white matter of the immature ovine brain.
Topics: Animals; Apoptosis; Axons; Brain; Caffeine; Female; Gliosis; Maternal Exposure; Myelin Basic Protein | 2014 |
Exploring maternal patterns of dietary caffeine consumption before conception and during pregnancy.
Topics: Adolescent; Adult; Beverages; Caffeine; Carbonated Beverages; Case-Control Studies; Central Nervous | 2014 |
Prenatal caffeine intake differently affects synaptic proteins during fetal brain development.
Topics: Age Factors; Animals; Animals, Newborn; Brain; Brain-Derived Neurotrophic Factor; Caffeine; Central | 2014 |
Maternal caffeine exposure impairs insulin secretion by pancreatic β-cells and increases the risk of type II diabetes mellitus in offspring.
Topics: Animals; Apoptosis; Birth Weight; Blood Glucose; Caffeine; Cells, Cultured; Diabetes Mellitus, Type | 2014 |
First trimester coffee and tea intake and risk of gestational diabetes mellitus: a study within a national birth cohort.
Topics: Adult; Caffeine; Coffee; Cohort Studies; Denmark; Diabetes, Gestational; Female; Humans; Infant, New | 2015 |
Anti-inflammatory effect of caffeine is associated with improved lung function after lipopolysaccharide-induced amnionitis.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Caffeine; Chorioamnionitis; Disease Models, Ani | 2014 |
Coffee and tea consumption in pregnancy not associated with gestational diabetes mellitus.
Topics: Caffeine; Coffee; Diabetes, Gestational; Female; Humans; Male; Pregnancy; Pregnancy Trimester, First | 2015 |
Phenotype refinement strengthens the association of AHR and CYP1A1 genotype with caffeine consumption.
Topics: Adult; Basic Helix-Loop-Helix Transcription Factors; Caffeine; Cytochrome P-450 CYP1A1; Drinking Beh | 2014 |
Store-operated Ca²⁺ entry and depolarization explain the anomalous behaviour of myometrial SR: effects of SERCA inhibition on electrical activity, Ca²⁺ and force.
Topics: Action Potentials; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium S | 2014 |
Comparison of maternal and fetal blood levels of caffeine and its metabolite. A pilot study.
Topics: Adult; Caffeine; Female; Fetal Blood; Humans; Infant, Newborn; Logistic Models; Male; Pilot Projects | 2014 |
Influence of caffeine on the expression of human chorionic gonadotropin and progesterone receptors in human trophoblast cell lines.
Topics: Caffeine; Cell Line; Corpus Luteum; Female; Humans; Pregnancy; Pregnancy Trimester, First; Progester | 2014 |
Caffeine exposure alters cardiac gene expression in embryonic cardiomyocytes.
Topics: Animals; Caffeine; Cell Shape; Cell Survival; Cells, Cultured; DNA Methylation; Dose-Response Relati | 2014 |
Maternal caffeine intake during pregnancy and risk of obesity in offspring: a prospective cohort study.
Topics: Adolescent; Adult; Appetite Regulation; Body Mass Index; Caffeine; Central Nervous System Stimulants | 2015 |
Maternal caffeine exposure alters neuromotor development and hippocampus acetylcholinesterase activity in rat offspring.
Topics: Acetylcholinesterase; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Body Weight; Caf | 2015 |
Potential confounding still clouds the possible association of maternal caffeine intake and low birth weight.
Topics: Birth Weight; Caffeine; Female; Humans; Infant, Low Birth Weight; Male; Pregnancy; Prenatal Exposure | 2015 |
Influence of caffeine administered at 45 °C on bone tissue development.
Topics: Animals; Bone and Bones; Bone Development; Caffeine; Calcium; Female; Fetal Development; Hot Tempera | 2014 |
Maternal serum paraxanthine during pregnancy and offspring body mass index at ages 4 and 7 years.
Topics: Adult; Biomarkers; Body Mass Index; Caffeine; Case-Control Studies; Child; Child, Preschool; Female; | 2015 |
Osteogenic potential of osteoblasts from neonatal rats born to mothers treated with caffeine throughout pregnancy.
Topics: Alkaline Phosphatase; Animals; Caffeine; Calcification, Physiologic; Cell Differentiation; Cell Surv | 2015 |
Fetal ductus arteriosus constriction and closure: analysis of the causes and perinatal outcome related to 45 consecutive cases.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Flow Velocity; Caffeine; Central N | 2016 |
Gender-specific increase in susceptibility to metabolic syndrome of offspring rats after prenatal caffeine exposure with post-weaning high-fat diet.
Topics: Adrenocorticotropic Hormone; Age Factors; Analysis of Variance; Animal Nutritional Physiological Phe | 2015 |
Maternal total caffeine intake, mainly from Japanese and Chinese tea, during pregnancy was associated with risk of preterm birth: the Osaka Maternal and Child Health Study.
Topics: Adult; Asian People; Body Mass Index; Caffeine; Carbonated Beverages; Child Health; Coffee; Diet; Fe | 2015 |
Review: higher caffeine intake during pregnancy increases risk of low birth weight.
Topics: Birth Weight; Caffeine; Female; Humans; Infant, Low Birth Weight; Male; Pregnancy; Prenatal Exposure | 2015 |
Increased DNA methylation of scavenger receptor class B type I contributes to inhibitory effects of prenatal caffeine ingestion on cholesterol uptake and steroidogenesis in fetal adrenals.
Topics: Adrenal Glands; Aldosterone; Animals; Caffeine; CD36 Antigens; Central Nervous System Stimulants; Ch | 2015 |
2.8 Nutrition in pregnancy and lactation.
Topics: Alcohol Drinking; Body Mass Index; Breast Feeding; Caffeine; Calcium, Dietary; Dairy Products; Diet; | 2015 |
Low functional programming of renal AT2R mediates the developmental origin of glomerulosclerosis in adult offspring induced by prenatal caffeine exposure.
Topics: Animals; Caffeine; Creatinine; Female; Fetal Growth Retardation; Kidney Diseases; Male; Pregnancy; P | 2015 |
[Bronchopulmonary dysplasia in the newborn: physiopathology, treatment and prevention].
Topics: Anti-Bacterial Agents; Bronchopulmonary Dysplasia; Caffeine; Central Nervous System Stimulants; Fema | 2015 |
Investigating the effect of excess caffeine exposure on placental angiogenesis using chicken 'functional' placental blood vessel network.
Topics: Animals; Blood Vessels; Caffeine; Chickens; Female; Fetal Development; Mammals; Models, Animal; Plac | 2016 |
Chronic fetal exposure to caffeine altered resistance vessel functions via RyRs-BKCa down-regulation in rat offspring.
Topics: Animals; Blood Pressure; Body Weight; Caffeine; Calcium; Cells, Cultured; Down-Regulation; Female; L | 2015 |
[Does coffee during pregnancy harm the baby?].
Topics: Caffeine; Coffee; Dose-Response Relationship, Drug; Female; Fetal Development; Germany; Humans; Infa | 2015 |
Second-Trimester Maternal Serum Paraxanthine, CYP1A2 Activity, and the Risk of Severe Preeclampsia.
Topics: Adult; Caffeine; Case-Control Studies; Cytochrome P-450 CYP1A2; Female; Humans; Pre-Eclampsia; Pregn | 2015 |
Effect of early caffeine on neurodevelopmental outcome of very low-birth weight newborns.
Topics: Caffeine; Case-Control Studies; Central Nervous System Stimulants; Child Development; Chorioamnionit | 2016 |
Prenatal caffeine exposure induced a lower level of fetal blood leptin mainly via placental mechanism.
Topics: Adenylyl Cyclases; Animals; Caffeine; Cells, Cultured; Colforsin; Cyclic AMP Response Element-Bindin | 2015 |
Lifestyle habits of 12,800 IVF patients: Prevalence of negative lifestyle behaviors, and impact of region and insurance coverage.
Topics: Adult; Alcohol Drinking; Caffeine; Electronic Health Records; Exercise; Female; Fertilization in Vit | 2015 |
Prenatal Caffeine Exposure and Child IQ at Age 5.5 Years: The EDEN Mother-Child Cohort.
Topics: Adult; Caffeine; Child; Child Development; Child, Preschool; Cohort Studies; Female; Humans; Intelli | 2016 |
Perinatal Risk Factors Associated with the Obstructive Sleep Apnea Syndrome in School-Aged Children Born Preterm.
Topics: Apgar Score; Birth Weight; Caffeine; Child; Child, Preschool; Chorioamnionitis; Cohort Studies; Doub | 2016 |
Caffeine intake in pregnancy: Relationship between internal intake and effect on birth weight.
Topics: Adult; Birth Weight; Caffeine; Computer Simulation; Female; Humans; Infant, Newborn; Models, Biologi | 2015 |
Effect of ATM and HDAC Inhibition on Etoposide-Induced DNA Damage in Porcine Early Preimplantation Embryos.
Topics: Animals; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Blastocyst; Caffeine; DNA Damage; Embryo | 2015 |
Maternal Caffeine Intake During Pregnancy and Child Cognition and Behavior at 4 and 7 Years of Age.
Topics: Adult; Caffeine; Child; Child Behavior; Child, Preschool; Coffee; Cognition; Female; Follow-Up Studi | 2015 |
Inhibition of the osteogenic differentiation of mesenchymal stem cells derived from the offspring of rats treated with caffeine during pregnancy and lactation.
Topics: Alkaline Phosphatase; Animals; Antigens, CD; Caffeine; Calcification, Physiologic; Cell Differentiat | 2016 |
Prenatal caffeine exposure induces a poor quality of articular cartilage in male adult offspring rats via cholesterol accumulation in cartilage.
Topics: Animals; Biological Transport; Caffeine; Cartilage, Articular; Cholesterol; Diet, High-Fat; Female; | 2015 |
PERINATAL OUTCOMES OF PREMATURITY AND BIRTH WEIGHT ACCORDING TO MATERNAL CAFFEINE CONSUMPTION.
Topics: Adult; Birth Weight; Caffeine; Cross-Sectional Studies; Dose-Response Relationship, Drug; Female; Hu | 2015 |
Clinical associations of immature breathing in preterm infants: part 1-central apnea.
Topics: Algorithms; Apnea; Caffeine; Cohort Studies; Electrocardiography; Enterocolitis, Necrotizing; Female | 2016 |
The effects of caffeine administered at different temperatures on foetal development.
Topics: Animals; Caffeine; Female; Fetal Development; Pregnancy; Random Allocation; Rats; Rats, Wistar; Temp | 2016 |
Maternal caffeine intake during pregnancy, early growth, and body fat distribution at school age.
Topics: Birth Weight; Body Composition; Body Fat Distribution; Body Mass Index; Caffeine; Child; Coffee; Fem | 2016 |
Lifestyle and pregnancy loss in a contemporary cohort of women recruited before conception: The LIFE Study.
Topics: Abortion, Spontaneous; Adult; Alcohol Drinking; Caffeine; Chi-Square Distribution; Female; Humans; I | 2016 |
Re: "Maternal Caffeine Intake During Pregnancy and Child Cognition and Behavior at 4 and 7 Years of Age".
Topics: Caffeine; Child; Cognition; Female; Humans; Pregnancy; Prospective Studies | 2016 |
Behavioral profile assessment in offspring of Swiss mice treated during pregnancy and lactation with caffeine.
Topics: Animals; Anxiety; Caffeine; Central Nervous System Stimulants; Female; Hyperalgesia; Lactation; Male | 2016 |
Intake of Caffeinated Soft Drinks before and during Pregnancy, but Not Total Caffeine Intake, Is Associated with Increased Cerebral Palsy Risk in the Norwegian Mother and Child Cohort Study.
Topics: Adult; Caffeine; Carbonated Beverages; Cerebral Palsy; Female; Humans; Infant, Low Birth Weight; Inf | 2016 |
Effects of Oral Maternal Administration of Caffeine on Reproductive Functions of Male Offspring of Wistar Rats.
Topics: Administration, Oral; Animals; Caffeine; Female; Male; Maternal Exposure; Pregnancy; Prenatal Exposu | 2015 |
Pre-pregnancy caffeine and caffeinated beverage intake and risk of spontaneous abortion.
Topics: Abortion, Spontaneous; Adult; Beverages; Body Mass Index; Caffeine; Carbonated Beverages; Coffee; Di | 2018 |
Smoking, alcohol and caffeine in relation to two hormonal indicators of ovarian age during the reproductive years.
Topics: Adult; Alcohol Drinking; Anti-Mullerian Hormone; Caffeine; Cross-Sectional Studies; Female; Follicle | 2016 |
Should Pregnant Women Worry About Caffeine?
Topics: Caffeine; Female; Humans; Pregnancy; Pregnancy Complications; Smoking | 2016 |
Ryanodine receptor type 3 does not contribute to contractions in the mouse myometrium regardless of pregnancy.
Topics: Animals; Caffeine; Calcium; Calcium Signaling; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockou | 2017 |
Caffeine consumption during pregnancy and ADHD at the age of 11 years: a birth cohort study.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Brazil; Caffeine; Central Nervous System Stimu | 2016 |
Caffeine combined with sedative/anesthetic drugs triggers widespread neuroapoptosis in a mouse model of prematurity.
Topics: Anesthetics; Animals; Animals, Newborn; Apoptosis; Caffeine; Disease Models, Animal; Female; Humans; | 2017 |
A Newborn Infant With Oxygen Desaturation During Sleep.
Topics: Apgar Score; Caffeine; Central Nervous System Stimulants; Diabetes, Gestational; Female; Gestational | 2017 |
Caffeine Intake During Pregnancy in Different Intrauterine Environments and its Association with Infant Anthropometric Measurements at 3 and 6 Months of Age.
Topics: Adult; Anthropometry; Body Weight; Brazil; Caffeine; Central Nervous System Stimulants; Child Develo | 2017 |
Male caffeine and alcohol intake in relation to semen parameters and in vitro fertilization outcomes among fertility patients.
Topics: Adult; Alcohol Drinking; Caffeine; Female; Fertility; Fertilization in Vitro; Humans; Infertility; M | 2017 |
A low cost, simplified, and scaleable pneumotachograph and face mask for neonatal mouse respiratory measurements.
Topics: Animals; Animals, Newborn; Apnea; Caffeine; Central Nervous System Stimulants; Equipment Design; Fem | 2017 |
Effect of caffeine and morphine on the developing pre-mature brain.
Topics: Analysis of Variance; Animals; Animals, Newborn; Brain; Caffeine; Cell Count; Central Nervous System | 2008 |
Caffeine during pregnancy: how much is safe?
Topics: Caffeine; Coffee; Female; Fetal Development; Gestational Age; Humans; Maternal Welfare; Pregnancy; P | 2008 |
Placental passage of benzoic acid, caffeine, and glyphosate in an ex vivo human perfusion system.
Topics: Adult; Benzoic Acid; Caffeine; Female; Glycine; Glyphosate; Humans; In Vitro Techniques; Maternal-Fe | 2008 |
Nails of newborns in monitoring drug exposure during pregnancy.
Topics: Caffeine; Central Nervous System Stimulants; Cocaine; Cotinine; Dopamine Uptake Inhibitors; Female; | 2008 |
Chemoprevention of dibenzo[a,l]pyrene transplacental carcinogenesis in mice born to mothers administered green tea: primary role of caffeine.
Topics: Animals; Anticarcinogenic Agents; Benzopyrenes; Caffeine; Carcinogens; Catechin; Chemoprevention; Fe | 2008 |
Genetic evidence for functional role of ryanodine receptor 1 in pulmonary artery smooth muscle cells.
Topics: Animals; Caffeine; Calcium; Calcium Signaling; Female; Hypoxia; Membrane Potentials; Mice; Mice, Kno | 2009 |
Maternal caffeine consumption during pregnancy and the risk of miscarriage.
Topics: Abortion, Spontaneous; Caffeine; Female; Humans; Pregnancy | 2008 |
Caffeine and miscarriage: case closed?
Topics: Abortion, Spontaneous; Caffeine; Female; Humans; Pregnancy | 2008 |
Is caffeine use during pregnancy really unsafe?
Topics: Abortion, Spontaneous; Caffeine; Female; Humans; Pregnancy; Research Design | 2008 |
Coffee and caffeine intake and the risk of ovarian cancer: the Iowa Women's Health Study.
Topics: Aged; Caffeine; Carcinoma; Central Nervous System Stimulants; Coffee; Cohort Studies; Confidence Int | 2008 |
Maternal caffeine ingestion during gestation and lactation influences respiratory adaptation to acute alveolar hypoxia in newborn rats and adenosine A2A and GABA A receptor mRNA transcription.
Topics: Adaptation, Physiological; Animals; Animals, Newborn; Body Temperature; Caffeine; Cell Count; Female | 2008 |
Semen quality according to prenatal coffee and present caffeine exposure: two decades of follow-up of a pregnancy cohort.
Topics: Adult; Caffeine; Coffee; Female; Follow-Up Studies; Humans; Inhibins; Male; Maternal-Fetal Exchange; | 2008 |
Coffee consumption during pregnancy and the risk of hyperkinetic disorder and ADHD: a prospective cohort study.
Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Caffeine; Central Nervous System S | 2009 |
Re: Habitual caffeine intake in women of childbearing age.
Topics: Caffeine; Coffee; Feeding Behavior; Female; Humans; Pregnancy | 2008 |
Decreased behavioral activation following caffeine, amphetamine and darkness in A3 adenosine receptor knock-out mice.
Topics: Amphetamine; Analysis of Variance; Animals; Caffeine; Central Nervous System Stimulants; Darkness; E | 2008 |
[Does propofol have effect on postdural puncture headache?].
Topics: Adult; Anesthesia, Spinal; Bed Rest; Blood Patch, Epidural; Caffeine; Combined Modality Therapy; Fem | 2008 |
Caffeine intake during pregnancy.
Topics: Caffeine; Coffee; Female; Fetal Growth Retardation; Humans; Pregnancy | 2008 |
Maternal caffeine intake during pregnancy and risk of fetal growth restriction: a large prospective observational study.
Topics: Adolescent; Adult; Birth Weight; Caffeine; Cotinine; Female; Fetal Growth Retardation; Gestational A | 2008 |
Caffeine in miscarriages: it's not just in the coffee.
Topics: Abortion, Spontaneous; Caffeine; Female; Humans; Pregnancy | 2008 |
Embryonic caffeine exposure induces adverse effects in adulthood.
Topics: Animals; Caffeine; Embryo, Mammalian; Female; Growth; Hypoxia; Maternal Exposure; Maternal-Fetal Exc | 2009 |
Perinatal caffeine, acting on maternal adenosine A(1) receptors, causes long-lasting behavioral changes in mouse offspring.
Topics: Algorithms; Animals; Animals, Newborn; Behavior, Animal; Caffeine; Cocaine; Female; Gene Expression | 2008 |
[Caffeine consumption by pregnant women selected from a Health Care Center in the municipality of Rio de Janeiro, Brazil].
Topics: Adult; Brazil; Caffeine; Coffee; Cross-Sectional Studies; Drinking; Female; Humans; Life Style; Nutr | 2008 |
Caffeine in pregnancy. Food Standard Agency's advice on caffeine.
Topics: Caffeine; Female; Fetal Growth Retardation; Government Agencies; Humans; Pregnancy; Prenatal Care; R | 2009 |
Cut caffeine in pregnancy?
Topics: Caffeine; Female; Fetal Growth Retardation; Humans; Pregnancy | 2009 |
Effects of caffeine, cumulus cell removal and aging on polyspermy and embryo development on in vitro matured and fertilized ovine oocytes.
Topics: Animals; Caffeine; Culture Media; Cumulus Cells; Embryo Culture Techniques; Embryo Transfer; Embryo, | 2009 |
Maternal exposure to tobacco smoke, alcohol and caffeine, and risk of anorectal atresia: National Birth Defects Prevention Study 1997-2003.
Topics: Adult; Alcohol Drinking; Anal Canal; Anus, Imperforate; Caffeine; Case-Control Studies; Central Nerv | 2009 |
[Smoking, alcohol and caffeine consumption of mothers before, during and after pregnancy--results of the study 'breast-feeding habits in Bavaria'].
Topics: Adult; Alcohol Drinking; Breast Feeding; Caffeine; Cohort Studies; Comorbidity; Female; Germany; Hum | 2009 |
Maternal consumption of coffee and caffeine-containing beverages and oral clefts: a population-based case-control study in Norway.
Topics: Caffeine; Case-Control Studies; Cleft Lip; Cleft Palate; Coffee; Confidence Intervals; Female; Healt | 2009 |
Effects of Sri Lankan black tea (Camellia sinensis L.) on pregnancy of rats.
Topics: Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Body Weights and Measures; Ca | 2009 |
Caffeine in pregnancy: a cause for concern?
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Caffeine; Central Nervous System Stimulants; F | 2009 |
Maternal caffeine intake during pregnancy and orofacial clefts.
Topics: Adult; Caffeine; Case-Control Studies; Cleft Lip; Cleft Palate; Female; Humans; Infant, Newborn; Pha | 2009 |
Modeling placental transport: correlation of in vitro BeWo cell permeability and ex vivo human placental perfusion.
Topics: Antipyrine; Benzoic Acid; Caffeine; Cell Line; Cell Membrane Permeability; Female; Glycine; Glyphosa | 2009 |
Caffeine levels in beverages from Argentina's market: application to caffeine dietary intake assessment.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Argentina; Beverages; Cacao; Caffe | 2009 |
Chronic prenatal caffeine exposure impairs novel object recognition and radial arm maze behaviors in adult rats.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Female; Learning Disabilities; Male; Maze Lear | 2009 |
Do women change their health behaviours in pregnancy? Findings from the Southampton Women's Survey.
Topics: Adult; Alcohol Drinking; Caffeine; Cohort Studies; Diet; England; Female; Health Behavior; Humans; L | 2009 |
Caffeine's implications for women's health and survey of obstetrician-gynecologists' caffeine knowledge and assessment practices.
Topics: Adult; Attitude of Health Personnel; Caffeine; Central Nervous System Stimulants; Coffee; Female; Gy | 2009 |
Maternal caffeine consumption and risk of neural tube defects.
Topics: Caffeine; Case-Control Studies; Female; Humans; Maternal Exposure; Neural Tube Defects; Pregnancy; R | 2009 |
Caffeine consumption and miscarriage: a prospective cohort study.
Topics: Abortion, Spontaneous; Beverages; Caffeine; Central Nervous System Stimulants; Female; Humans; Pregn | 2010 |
Improved fertility in gilts and sows after artificial insemination of frozen-thawed boar semen by supplementation of semen extender with caffeine and CaCl2.
Topics: Animal Husbandry; Animals; Caffeine; Calcium Chloride; Cell Survival; Cryopreservation; Cryoprotecti | 2009 |
Factors associated with subfertility among women attending an antenatal clinic in Hull.
Topics: Adult; Alcohol Drinking; Body Mass Index; Caffeine; England; Female; Humans; Incidence; Infertility, | 2009 |
Maternal caffeine intake during gestation and lactation down-regulates adenosine A1 receptor in rat brain from mothers and neonates.
Topics: Animals; Animals, Newborn; Brain; Caffeine; Central Nervous System Stimulants; Female; Lactation; Ma | 2010 |
[Side effects of caffeine].
Topics: Abortion, Spontaneous; Arteries; Caffeine; Cholesterol; Coronary Disease; Cytochrome P-450 CYP1A2; C | 2009 |
Intrauterine exposure to caffeine and inattention/overactivity in children.
Topics: Adolescent; Adult; Analysis of Variance; Attention Deficit Disorder with Hyperactivity; Caffeine; Fe | 2010 |
Caffeine intake during pregnancy, late miscarriage and stillbirth.
Topics: Abortion, Spontaneous; Adolescent; Adult; Caffeine; Dose-Response Relationship, Drug; Female; Fetus; | 2010 |
The potential dangers of caffeine in pregnancy.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Caffeine; Central Nervous System Stimulants; C | 2010 |
A study on neonatal factors and eruption time of primary teeth.
Topics: Birth Weight; Caffeine; Child, Preschool; Female; Gestational Age; Humans; Infant; Infant, Newborn; | 2010 |
Maternal caffeine intake from coffee and tea, fetal growth, and the risks of adverse birth outcomes: the Generation R Study.
Topics: Adolescent; Adult; Birth Weight; Caffeine; Coffee; Cohort Studies; Dose-Response Relationship, Drug; | 2010 |
Microtubule distribution in somatic cell nuclear transfer bovine embryos following control of nuclear remodeling type.
Topics: Animals; Caffeine; Cattle; Cell Nucleus; Female; Fertilization in Vitro; Male; Microscopy, Confocal; | 2010 |
A review of the epidemiologic evidence concerning the reproductive health effects of caffeine consumption: a 2000-2009 update.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Caffeine; Central Nervous System Stimulants; Fem | 2010 |
Caffeine, selected metabolic gene variants, and risk for neural tube defects.
Topics: Acetylation; Adolescent; Adult; Arylamine N-Acetyltransferase; Caffeine; Case-Control Studies; Cytoc | 2010 |
ACOG CommitteeOpinion No. 462: Moderate caffeine consumption during pregnancy.
Topics: Abortion, Spontaneous; Beverages; Caffeine; Female; Fetal Growth Retardation; Food; Humans; Pregnanc | 2010 |
Changes in thickness of each layer of developing chicken cornea after administration of caffeine.
Topics: Animals; Caffeine; Chick Embryo; Cornea; Female; Humans; Infant; Phosphodiesterase Inhibitors; Pregn | 2010 |
Caffeine treatment of ovine cytoplasts regulates gene expression and foetal development of embryos produced by somatic cell nuclear transfer.
Topics: Animals; Blastocyst; Caffeine; Embryonic Development; Female; Fertilization in Vitro; Gene Expressio | 2010 |
Effects of administration of caffeine on metabolic variables in neonatal pigs with peripartum asphyxia.
Topics: Animals; Animals, Newborn; Asphyxia; Caffeine; Central Nervous System Stimulants; Female; Obstetric | 2010 |
The effect of caffeine consumption on the success rate of pregnancy as well various performance parameters of in-vitro fertilization treatment.
Topics: Abortion, Spontaneous; Caffeine; Central Nervous System Stimulants; Coffee; Female; Fertilization in | 2010 |
Maternal caffeine intake, blood pressure, and the risk of hypertensive complications during pregnancy. The Generation R Study.
Topics: Blood Pressure; Caffeine; Cohort Studies; Female; Humans; Hypertension; Hypertension, Pregnancy-Indu | 2011 |
Caffeine intake and risk of neural tube defects.
Topics: Caffeine; Female; Humans; Maternal Exposure; Neural Tube Defects; Pregnancy; Risk Factors | 2011 |
Maternal caffeine intake and risk of selected birth defects in the National Birth Defects Prevention Study.
Topics: Adolescent; Adult; Caffeine; Case-Control Studies; Congenital Abnormalities; Congenital Microtia; Cr | 2011 |
Caffeine and insulin resistance in pregnancy.
Topics: Birth Weight; Caffeine; Female; Homeostasis; Humans; Infant, Newborn; Insulin Resistance; Male; Preg | 2011 |
Caffeine can be used for oocyte enucleation.
Topics: Animals; Caffeine; Cell Nucleus; Cysteine Proteinase Inhibitors; Demecolcine; Dose-Response Relation | 2011 |
Maternal caffeine consumption and sine causa recurrent miscarriage.
Topics: Abortion, Habitual; Adult; Caffeine; Case-Control Studies; Eating; Female; Humans; Pregnancy; Pregna | 2011 |
alcohol, smoking, and caffeine in relation to fecundability, with effect modification by NAT2.
Topics: Acetylation; Adult; Alcohol Drinking; Arylamine N-Acetyltransferase; Caffeine; Female; Fertility; Hu | 2011 |
Left ventricular assist device in pregnancy.
Topics: Adolescent; Anticoagulants; Betamethasone; Bradycardia; Caffeine; Cardiomyopathies; Cesarean Section | 2011 |
The influence of caffeine on the biomechanical properties of bone tissue during pregnancy in a population of rats.
Topics: Animals; Biomechanical Phenomena; Body Weight; Bone and Bones; Bone Density; Caffeine; Calcification | 2011 |
Effect of the addition of beta-mercaptoethanol to a thawing solution supplemented with caffeine on the function of frozen-thawed boar sperm and on the fertility of sows after artificial insemination.
Topics: Acrosome Reaction; Animals; Antioxidants; Caffeine; Cells, Cultured; Chorionic Gonadotropin; Cryopre | 2012 |
Maternal caffeine intake and its effect on pregnancy outcomes.
Topics: Adolescent; Adult; Age Factors; Apgar Score; Beverages; Birth Weight; Caffeine; Female; Fetal Develo | 2012 |
Prenatal health behaviors and postpartum depression: is there an association?
Topics: Adult; Caffeine; Depression, Postpartum; Female; Health Behavior; Humans; Interviews as Topic; New E | 2012 |
Role of p53-dependent placental apoptosis in the reproductive and developmental toxicities of caffeine in rodents.
Topics: Animals; Apoptosis; Caffeine; Dose-Response Relationship, Drug; Female; Fertilization; Fetal Develop | 2012 |
Rhabdomyolysis: not a textbook case.
Topics: Caffeine; Carbonated Beverages; Central Nervous System Stimulants; Female; Fructose; Glucose; Humans | 2012 |
Effects of monensin on metabolic parameters, feeding behavior, and productivity of transition dairy cows.
Topics: Animals; Antiprotozoal Agents; Body Weight; Caffeine; Cattle; Diet; Drinking; Eating; Fatty Acids, N | 2012 |
Caffeinated beverage and soda consumption and time to pregnancy.
Topics: Adolescent; Adult; Beverages; Caffeine; Carbonated Beverages; Central Nervous System Stimulants; Cof | 2012 |
Maternal caffeine consumption and infant nighttime waking: prospective cohort study.
Topics: Adult; Arousal; Brazil; Breast Feeding; Caffeine; Cohort Studies; Dose-Response Relationship, Drug; | 2012 |
Fetal rat metabonome alteration by prenatal caffeine ingestion probably due to the increased circulatory glucocorticoid level and altered peripheral glucose and lipid metabolic pathways.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Female; Fetus; Glucocorticoids; Glucose; Lipid | 2012 |
Maternal hypoxia and caffeine exposure depress fetal cardiovascular function during primary organogenesis.
Topics: Animals; Caffeine; Female; Fetal Heart; Heart Rate, Fetal; Hemodynamics; Hypoxia; Male; Mice; Organo | 2012 |
Coffee, caffeine and health: what's in your cup?
Topics: Caffeine; Coffea; Coffee; Female; Health; Humans; Pregnancy | 2012 |
Does nausea and vomiting of pregnancy play a role in the association found between maternal caffeine intake and fetal growth restriction?
Topics: Adolescent; Adult; Caffeine; Female; Fetal Development; Fetal Growth Retardation; Gestational Age; H | 2013 |
When the patient asks. Is caffeine safe duiring pregnancy?
Topics: Abortion, Spontaneous; Breast Feeding; Caffeine; Central Nervous System Stimulants; Female; Fetus; H | 2012 |
Patient information. Is caffeine safe during pregnancy?
Topics: Abortion, Spontaneous; Breast Feeding; Caffeine; Central Nervous System Stimulants; Female; Fetus; H | 2012 |
A pregnancy physiologically based pharmacokinetic (p-PBPK) model for disposition of drugs metabolized by CYP1A2, CYP2D6 and CYP3A4.
Topics: Adult; Caffeine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Drug Desi | 2012 |
[Is there any point in pharmacological prophylaxis of PDPH (post-dural puncture headache) after spinal anaesthesia for Caesaren section?].
Topics: Adolescent; Adult; Aminophylline; Anesthesia, Obstetrical; Anesthesia, Spinal; Antibiotic Prophylaxi | 2012 |
Caffeine intake during pregnancy and risk of problem behavior in 5- to 6-year-old children.
Topics: Affective Symptoms; Attention Deficit Disorder with Hyperactivity; Caffeine; Child; Child Behavior D | 2012 |
Nutritional intake and dietary patterns in pregnancy: a longitudinal study of women with lifetime eating disorders.
Topics: Adult; Anorexia Nervosa; Bulimia Nervosa; Caffeine; Cohort Studies; Diet; Diet, Vegetarian; Dietary | 2012 |
Caffeine inhibits EGF-stimulated trophoblast cell motility through the inhibition of mTORC2 and Akt.
Topics: Blotting, Western; Caffeine; Cell Line; Cell Movement; Epidermal Growth Factor; Female; Humans; Preg | 2012 |
A hypothalamic-pituitary-adrenal axis-associated neuroendocrine metabolic programmed alteration in offspring rats of IUGR induced by prenatal caffeine ingestion.
Topics: Animals; Birth Weight; Blood Glucose; Caffeine; Female; Fetal Growth Retardation; Hippocampus; Hypot | 2012 |
Maternal high-altitude hypoxia and suppression of ryanodine receptor-mediated Ca2+ sparks in fetal sheep pulmonary arterial myocytes.
Topics: Acclimatization; Analysis of Variance; Animals; Caffeine; Calcium Channel Agonists; Calcium Signalin | 2012 |
Caffeine-induced activated glucocorticoid metabolism in the hippocampus causes hypothalamic-pituitary-adrenal axis inhibition in fetal rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Caffeine; DNA Methylation; Female; Glucocortic | 2012 |
Caffeine-induced fetal rat over-exposure to maternal glucocorticoid and histone methylation of liver IGF-1 might cause skeletal growth retardation.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Female; Femur; Fetal Development; Fetal Growth | 2012 |
[Coffee can protect against disease].
Topics: Alzheimer Disease; Anxiety; Caffeine; Cardiovascular Diseases; Coffee; Cognition; Diabetes Mellitus, | 2012 |
Spontaneous abortion and a diet drug containing caffeine and ephedrine: a study within the Danish national birth cohort.
Topics: Abortion, Spontaneous; Anti-Obesity Agents; Caffeine; Cohort Studies; Denmark; Drug Combinations; Ep | 2012 |
Maternal caffeine administration leads to adverse effects on adult mice offspring.
Topics: Angiotensin II; Animals; Blood Pressure; Caffeine; Dose-Response Relationship, Drug; Female; Heart; | 2013 |
Effects of caffeine and/or nasal CPAP treatment on laryngeal chemoreflexes in preterm lambs.
Topics: Animals; Animals, Newborn; Apnea; Arterial Pressure; Bradycardia; Caffeine; Continuous Positive Airw | 2013 |
Adenosine A1 receptor down-regulation in mothers and fetal brain after caffeine and theophylline treatments to pregnant rats.
Topics: Animals; Binding, Competitive; Brain; Caffeine; Down-Regulation; Female; Gestational Age; Pregnancy; | 2002 |
Pregnancy hormone metabolite patterns, pregnancy symptoms, and coffee consumption.
Topics: Adult; Caffeine; Chorionic Gonadotropin; Coffee; Estrone; Female; Humans; Nausea; Pregnancy; Pregnan | 2002 |
Interactions of caffeine and restraint stress during pregnancy in mice.
Topics: Animals; Body Weight; Caffeine; Embryonic and Fetal Development; Female; Fetal Resorption; Fetus; Hu | 2002 |
Consequences of in utero caffeine exposure on respiratory output in normoxic and hypoxic conditions and related changes of Fos expression: a study on brainstem-spinal cord preparations isolated from newborn rats.
Topics: Animals; Animals, Newborn; Brain Stem; Caffeine; Carbon Dioxide; Electrophysiology; Female; Hypoxia, | 2003 |
Association of maternal caffeine consumption with decrements in fetal growth.
Topics: Adult; Birth Weight; Caffeine; Confounding Factors, Epidemiologic; Connecticut; Female; Fetal Growth | 2003 |
Cigarette, alcohol, and caffeine consumption: risk factors for spontaneous abortion.
Topics: Abortion, Spontaneous; Adolescent; Adult; Alcohol Drinking; Caffeine; Case-Control Studies; Coffee; | 2003 |
The effect of smoking and caffeine on the fetus and placenta in pregnancy.
Topics: Anthropometry; Birth Weight; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship | 2003 |
High dose of caffeine administered to pregnant rats causes histopathological changes in the cornea of newborn pups.
Topics: Animals; Animals, Newborn; Caffeine; Cornea; Dose-Response Relationship, Drug; Endothelium, Corneal; | 2003 |
Oxidative DNA damage in human sperm influences time to pregnancy.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Alcohol Drinking; Caffeine; Deoxyguanosine; DNA; DNA Damage; Fem | 2003 |
Consumption of coffee during pregnancy: article raises more questions than it answers.
Topics: Caffeine; Coffee; Female; Fetal Death; Humans; Infant Mortality; Infant, Newborn; Pregnancy; Prenata | 2003 |
Caffeine enhances the expression of the angiotensin II Type 2 receptor mRNA in BeWo cell culture and in the rat placenta.
Topics: Animals; Caffeine; Cell Line; Diet; Female; Gene Expression Regulation, Developmental; Gestational A | 2003 |
[Coffee and stillbirth].
Topics: Caffeine; Coffee; Female; Fetal Death; Humans; Infant, Newborn; Pregnancy; Risk Factors; Sudden Infa | 2003 |
Tobacco, alcohol and caffeine use in a low-income, pregnant population.
Topics: Adult; Age Factors; Alcohol Drinking; Caffeine; Ethnicity; Female; Humans; Logistic Models; Mass Scr | 2003 |
Caffeine intake and the risk of spontaneous abortion.
Topics: Abortion, Spontaneous; Adult; Caffeine; Case-Control Studies; Female; Humans; Odds Ratio; Pregnancy; | 2003 |
[Use of caffeine and bromides in vomiting in pregnancy].
Topics: Bromides; Caffeine; Female; Humans; Pregnancy; Pregnancy Complications; Vomiting | 1953 |
[Treatment of hypermesis gravidarum with bromides and caffeine with EEG control].
Topics: Bromides; Caffeine; Electroencephalography; Female; Humans; Pregnancy; Pregnancy Complications; Vomi | 1953 |
Intravenous caffeine in prevention of neonatal asphyxia and narcosis.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Asphyxia; Asphyxia Neonatorum; Caffeine; Female; Hu | 1954 |
Saddle block anesthesia in obstetrics; treatment of postpartum spinal headache.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Spinal; Caffeine; Ergot Alkaloids; Fema | 1955 |
[The treatment of uncontrollable vomiting in children by a combination of dramamine and vitamin B6].
Topics: Caffeine; Child; Dimenhydrinate; Female; Humans; Pregnancy; Vitamin B 6; Vomiting | 1955 |
[Treatment of threatened abortion with bromides, caffeine and psychotherapy].
Topics: Abortion, Induced; Abortion, Threatened; Bromides; Caffeine; Female; Humans; Pregnancy; Psychotherap | 1955 |
[Distribution of labeled caffeine in animal organism and its penetration from mother to fetus].
Topics: Animal Structures; Animals; Caffeine; Female; Fetus; Humans; Mothers; Placenta; Pregnancy | 1955 |
[Formation of gastric ulcers in pregnant and nonpregnant rats in the light of data on dominance of gestation].
Topics: Animals; Caffeine; Female; Light; Peptic Ulcer; Pregnancy; Rats; Stomach Ulcer | 1961 |
[On experiences with neural therapy in gynecology and obstetrics].
Topics: Caffeine; Female; Gynecology; Obstetrics; Pregnancy; Pregnancy Complications; Procaine | 1962 |
Passage of caffeine into human gonadal and fetal tissue.
Topics: Caffeine; Female; Fetus; Gonads; Humans; Placenta; Pregnancy | 1962 |
[SOME FEATURES OF THE ETIOLOGY, CLINICAL PICTURE AND THERAPY OF SPONTANEOUS AND HABITUAL ABORTION].
Topics: Abortion, Habitual; Abortion, Induced; Abortion, Spontaneous; Bromides; Caffeine; Central Nervous Sy | 1963 |
[DIAGNOSIS AND THERAPY OF RESPIRATORY DISORDERS IN THE NEWBORN].
Topics: Asphyxia Neonatorum; Caffeine; Cerebral Hemorrhage; Cyanosis; Diagnosis; Exchange Transfusion, Whole | 1963 |
[ANALYSIS OF THE POSSIBLE RELATION OF FETAL DAMAGE AND DRUGS. V. PRELIMINARY STUDY ON THE INFLUENCE OF 4 ANTIEMETICS ON FETAL DEVELOPMENT].
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Abortion, Spontaneous; Antiemetics; Birth Weight; Ca | 1964 |
TREATMENT OF POSTPARTUM PAIN WITH FIORINAL.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Barbiturates; Biomedical Research; Caff | 1964 |
FURTHER STUDIES ON THE EFFECTS OF INTRAUTERINE VASOCONSTRICTORS ON THE FETAL RAT LENS.
Topics: Animals; Caffeine; Carbohydrate Metabolism; Citric Acid Cycle; Ergotamine; Female; Fetus; Histocytoc | 1964 |
[BIOCHEMICAL STUDIES ON THE MATURATION OF FETAL CONNECTIVE TISSUE UNDER THE INFLUENCE OF DIPHENYLPYRALINE-8-CHLOROTHEOPHYLLINATE AND CAFFEINE].
Topics: Anti-Allergic Agents; Caffeine; Connective Tissue; Elastin; Fetus; Glycosaminoglycans; Hexosamines; | 1964 |
[ON THE PRENATAL TOXICITY OF DIPHENYLPYRALINE 8-CHLOROTHEOPHYLLINATE WITH REFERENCE TO EXPERIENCES WITH THALIDOMIDE AND CAFFEINE].
Topics: Abnormalities, Drug-Induced; Anti-Allergic Agents; Caffeine; Fetal Death; Histamine H1 Antagonists; | 1964 |
[THE PROCEDURES FOR THE TESTING OF TERATOGENIC EFFECTS TAKE SHAPE].
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Female; Haplorhini; Humans; Pregnancy; Sodium Chlori | 1965 |
URINARY VOLUME AND EXCRETION OF OESTROGENS IN LATE PREGNANCY.
Topics: Body Fluids; Caffeine; Diuresis; Estradiol; Estriol; Estrogens; Estrone; Female; Glucose Tolerance T | 1965 |
[Comparative results in the treatment of early pregnancy toxemias with bromine, caffeine and aminazin].
Topics: Bromides; Bromine; Caffeine; Chlorpromazine; Female; Pre-Eclampsia; Pregnancy; Toxemia | 1962 |
The effect of caffeine consumption and nausea on the risk of miscarriage.
Topics: Abortion, Spontaneous; Adult; Beverages; Caffeine; Case-Control Studies; Coffee; Dose-Response Relat | 2003 |
High caffeine consumption in the third trimester of pregnancy: gender-specific effects on fetal growth.
Topics: Adult; Beverages; Caffeine; Case-Control Studies; Female; Fetal Growth Retardation; Humans; Infant, | 2003 |
Capillary electrophoretic determination of theanine, caffeine, and catechins in fresh tea leaves and oolong tea and their effects on rat neurosphere adhesion and migration.
Topics: Animals; Caffeine; Camellia sinensis; Catechin; Cell Adhesion; Cell Differentiation; Cell Movement; | 2003 |
Does caffeine and alcohol intake before pregnancy predict the occurrence of spontaneous abortion?
Topics: Abortion, Spontaneous; Adult; Caffeine; Case-Control Studies; Cohort Studies; Ethanol; Female; Human | 2003 |
Regarding "An unexpected distribution of sodium concentration in serum specimens stored for more than 30 years".
Topics: Abortion, Spontaneous; Adult; Bias; Caffeine; Female; Humans; Pregnancy; Risk Factors; Sodium; Speci | 2004 |
[Pregnancy and caffeine].
Topics: Abnormalities, Drug-Induced; Caffeine; Central Nervous System Stimulants; Coffee; Embryonic and Feta | 2003 |
[Use of bromides and caffeine in the treatment of pregnancy toxemias].
Topics: Bromides; Caffeine; Female; Humans; Pre-Eclampsia; Pregnancy | 1952 |
Maternal atopic disease modifies effects of prenatal risk factors on exhaled nitric oxide in infants.
Topics: Anthropometry; Asthma; Breath Tests; Caffeine; Coffee; Cohort Studies; Environmental Exposure; Fathe | 2004 |
Synopsis of the North American Diabetes in Pregnancy Study Group Conference in Little Rock, Arkansas, May 2003.
Topics: Blood Glucose; Caffeine; Cesarean Section; Congenital Abnormalities; Delivery, Obstetric; Diabetes, | 2004 |
Consequences of smoking and caffeine consumption during pregnancy in women with type 1 diabetes.
Topics: Abortion, Spontaneous; Adult; Birth Weight; Caffeine; Diabetes Mellitus, Type 1; Female; Humans; Pre | 2004 |
Caffeine suppresses the expression of the Bcl-2 mRNA in BeWo cell culture and rat placenta.
Topics: Animals; Base Sequence; Caffeine; Cell Line; DNA Primers; Female; Gene Expression Regulation; Placen | 2004 |
Changes in caffeine consumption as a signal of pregnancy.
Topics: Adolescent; Adult; Asian People; Black or African American; Caffeine; Chorionic Gonadotropin; Coffee | 2004 |
Developmental effects of propyphenazone in analgesic and antipyretic combination with caffeine or paracetamol.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Antipyrine; Caffeine; Dose-R | 2004 |
Involvement of adenosinergic A1 systems in the occurrence of respiratory perturbations encountered in newborns following an in utero caffeine exposure. a study on brainstem-spinal cord preparations isolated from newborn rats.
Topics: Adenosine; Animals; Animals, Newborn; Caffeine; Female; In Vitro Techniques; Medulla Oblongata; Neur | 2004 |
Caffeine and spontaneous abortion.
Topics: Abortion, Spontaneous; Caffeine; Chorionic Gonadotropin; Estrone; Female; Humans; Pregnancy; Pregnan | 2004 |
Coffee: for most, it's safe. Coffee has been blamed for everything from moral turpitude to cancer. But none of the bad raps have stuck. Coffee may even be good for you.
Topics: Caffeine; Cardiovascular System; Coffee; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Li | 2004 |
Excessive maternal caffeine exposure during pregnancy is cataractogenic for neonatal crystalline lenses in rats: a biomicroscopic and histopathologic study.
Topics: Animals; Animals, Newborn; Caffeine; Cataract; Dose-Response Relationship, Drug; Female; Lens, Cryst | 2004 |
Beverage caffeine intake in US consumers and subpopulations of interest: estimates from the Share of Intake Panel survey.
Topics: Adolescent; Adult; Age Factors; Aged; Beverages; Caffeine; Central Nervous System Stimulants; Child; | 2004 |
Food sources and intakes of caffeine in the diets of persons in the United States.
Topics: Adolescent; Adult; Age Factors; Aged; Beverages; Caffeine; Carbonated Beverages; Central Nervous Sys | 2005 |
Temporal changes in drug metabolism (CYP1A2, CYP2D6 and CYP3A Activity) during pregnancy.
Topics: Adolescent; Adult; Aryl Hydrocarbon Hydroxylases; Caffeine; Cytochrome P-450 CYP1A2; Cytochrome P-45 | 2005 |
Chronic caffeine or theophylline intake during pregnancy inhibits A1 receptor function in the rat brain.
Topics: Adenosine A1 Receptor Antagonists; Adenylyl Cyclases; Animals; Brain; Caffeine; Female; Pregnancy; P | 2005 |
Maternal caffeine intake impairs MK-801-induced hyperlocomotion in young rats.
Topics: Animals; Animals, Newborn; Caffeine; Central Nervous System Stimulants; Dizocilpine Maleate; Female; | 2005 |
Caffeine intake, CYP1A2 polymorphism and the risk of recurrent pregnancy loss.
Topics: Abortion, Habitual; Adult; Alleles; Caffeine; Case-Control Studies; Cytochrome P-450 CYP1A2; Female; | 2005 |
Effect of chronic gestational treatment with caffeine or theophylline on Group I metabotropic glutamate receptors in maternal and fetal brain.
Topics: Animals; Blotting, Western; Brain; Caffeine; Cell Membrane; Dose-Response Relationship, Drug; Drug I | 2005 |
Caffeine promotes premature chromosome condensation formation and in vitro development in porcine reconstructed embryos via a high level of maturation promoting factor activity during nuclear transfer.
Topics: Animals; Caffeine; Chromatin Assembly and Disassembly; Cloning, Organism; Embryo Culture Techniques; | 2005 |
N-acetyl-transferase phenotype and risk for preeclampsia.
Topics: Adult; Arylamine N-Acetyltransferase; Caffeine; Female; Genetic Predisposition to Disease; HELLP Syn | 2005 |
Coffee and fetal death: a cohort study with prospective data.
Topics: Abortion, Spontaneous; Adult; Age Distribution; Alcohol Drinking; Caffeine; Causality; Coffee; Cohor | 2005 |
In pregnant women who smoke, caffeine consumption is associated with an increased level of homocysteine.
Topics: Caffeine; Central Nervous System Stimulants; Coffee; Female; Homocysteine; Humans; Pregnancy; Prospe | 2005 |
Effect of coffee intake on blood flow and maternal stress during the third trimester of pregnancy.
Topics: Arteries; Caffeine; Case-Control Studies; Chromogranin A; Female; Fetus; Humans; Hydrocortisone; Mid | 2006 |
Intracellular Ca2+ regulation in rat motoneurons during development.
Topics: Animals; Caffeine; Calcium; Calcium Channels; Calcium Channels, L-Type; Calcium Signaling; Female; I | 2006 |
Caffeine dependence in combination with a family history of alcoholism as a predictor of continued use of caffeine during pregnancy.
Topics: Adult; Alcoholism; Behavior, Addictive; Caffeine; Coffee; Comorbidity; Family Health; Female; Humans | 2005 |
Secretion of brain-derived neurotrophic factor from PC12 cells in response to oxidative stress requires autocrine dopamine signaling.
Topics: Animals; Autocrine Communication; Boron Compounds; Brain; Brain-Derived Neurotrophic Factor; Butacla | 2006 |
Coffee drinking and risk of preterm birth.
Topics: Adolescent; Adult; Birth Weight; Caffeine; Case-Control Studies; Coffee; Female; Humans; Infant, New | 2006 |
Regarding "caffeine metabolism, genetics, and perinatal outcomes: a review of exposure assessment considerations during pregnancy".
Topics: Caffeine; Female; Fetal Development; Humans; Maternal Exposure; Pregnancy; Pregnancy Outcome | 2006 |
Reversal of neuronal migration in a mouse model of fetal alcohol syndrome by controlling second-messenger signalings.
Topics: Animals; Animals, Newborn; Caffeine; Cell Migration Inhibition; Cells, Cultured; Cerebellum; Disease | 2006 |
Caffeine in the milk prevents respiratory disorders caused by in utero caffeine exposure in rats.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Female; Hypoxia; Milk; Pregnancy; Prenatal Exp | 2006 |
Maternal caffeine consumption and fetal death: a case-control study in Uruguay.
Topics: Abortion, Spontaneous; Adult; Beverages; Caffeine; Case-Control Studies; Educational Status; Female; | 2006 |
Risks of repeated miscarriage.
Topics: Abortion, Spontaneous; Adult; Caffeine; Case-Control Studies; Cotinine; Dietary Supplements; Female; | 2006 |
Chronic intake of caffeine during gestation down regulates metabotropic glutamate receptors in maternal and fetal rat heart.
Topics: Animals; Brain; Caffeine; Central Nervous System Stimulants; Down-Regulation; Female; Fetal Heart; G | 2006 |
Caffeine metabolites in umbilical cord blood, cytochrome P-450 1A2 activity, and intrauterine growth restriction.
Topics: Adult; Biomarkers; Caffeine; Chi-Square Distribution; Connecticut; Cytochrome P-450 Enzyme System; F | 2006 |
Effect of postnatal exposure to caffeine on the pattern of adenosine A1 receptor distribution in respiration-related nuclei of the rat brainstem.
Topics: Age Factors; Animals; Animals, Newborn; Brain Stem; Caffeine; Central Nervous System Stimulants; Fem | 2006 |
Comparing attitudes about legal sanctions and teratogenic effects for cocaine, alcohol, tobacco and caffeine: a randomized, independent samples design.
Topics: Alcoholic Beverages; Attitude; Caffeine; Cocaine; Female; Humans; Illicit Drugs; Male; Mass Media; M | 2006 |
Stillbirth and slow metabolizers of caffeine: comparison by genotypes.
Topics: Acetyltransferases; Caffeine; Case-Control Studies; Cytochrome P-450 CYP1A2; Female; Genotype; Gluta | 2006 |
Environmental tobacco smoke and risk of spontaneous abortion.
Topics: Abortion, Spontaneous; Adult; Biomarkers; Caffeine; Case-Control Studies; Chromosome Aberrations; Co | 2006 |
Does caffeine in pregnancy cause birth defects?
Topics: Abnormalities, Drug-Induced; Caffeine; Central Nervous System Stimulants; Female; Humans; Pregnancy | 2006 |
Characteristics of thiamine uptake by the BeWo human trophoblast cell line.
Topics: Biological Transport; Caffeine; Cell Line, Tumor; Cell Membrane Structures; Ethanol; Female; Flavono | 2006 |
Neonatal caffeine administration causes a permanent increase in the dendritic length of prefrontal cortical neurons of rats.
Topics: Animals; Animals, Newborn; Caffeine; Central Nervous System Stimulants; Dendrites; Female; Motor Act | 2006 |
[Apnea of prematurity: risk factors and ambulatory treatment with caffeine citrate].
Topics: Ambulatory Care; Apnea; Birth Weight; Caffeine; Central Nervous System Stimulants; Citrates; Continu | 2006 |
Protective effects of caffeine on chronic hypoxia-induced perinatal white matter injury.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Animals, Newborn; Asphyxia Neonatorum; Brain; | 2006 |
[Blood patch in a patient with postdural puncture headache].
Topics: Accidents; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Bed Rest; Betamet | 2006 |
Neonatal withdrawal syndrome after chronic maternal drinking of mate.
Topics: Beverages; Breast Feeding; Caffeine; Female; Humans; Ilex paraguariensis; Infant, Newborn; Neonatal | 2007 |
Coffee and pregnancy.
Topics: Birth Weight; Caffeine; Coffee; Female; Humans; Pregnancy; Pregnancy Complications | 2007 |
Lifestyle during pregnancy and evidence based information.
Topics: Caffeine; Coffee; Diabetes, Gestational; Female; Humans; Life Style; Pregnancy | 2007 |
Coffee consumption and the risk of gestational diabetes mellitus.
Topics: Adult; Caffeine; Central Nervous System Stimulants; Coffee; Diabetes, Gestational; Dose-Response Rel | 2007 |
Diet & nutrition. Good news: caffeine in pregnancy doesn't affect the baby's growth...and folic acid seems to prevent cleft lip.
Topics: Birth Weight; Caffeine; Central Nervous System Stimulants; Cleft Lip; Coffee; Female; Fetal Developm | 2007 |
[The treatment of hyperemesis gravidarum with chlorobutanol-caffeine rectal suppositories in Denmark: practice and evidence].
Topics: Antiemetics; Caffeine; Chlorobutanol; Drug Combinations; Drug Utilization; Evidence-Based Medicine; | 2007 |
Maternal alcohol and coffee drinking, parental smoking and childhood leukaemia: a French population-based case-control study.
Topics: Adolescent; Alcohol Drinking; Caffeine; Case-Control Studies; Central Nervous System Stimulants; Chi | 2007 |
Caffeine intake and small-for-gestational-age birth: modifying effects of xenobiotic-metabolising genes and smoking.
Topics: Caffeine; Case-Control Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Female; Humans; In | 2007 |
Role of RYR3 splice variants in calcium signaling in mouse nonpregnant and pregnant myometrium.
Topics: Alternative Splicing; Animals; Caffeine; Calcium; Calcium Signaling; Cyclic ADP-Ribose; Female; Gene | 2007 |
The effects of caffeine on the preterm sheep ductus arteriosus.
Topics: Animals; Caffeine; Cardiovascular Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Dru | 2007 |
Perinatal dioxin exposure, cytochrome P-450 activity, liver functions and thyroid hormones at follow-up after 7-12 years.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Caffeine; Child; Cytochrome P-450 CYP1A2; Dioxins | 2008 |
The effects of methylmercury on motor activity are sex- and age-dependent, and modulated by genetic deletion of adenosine receptors and caffeine administration.
Topics: Aging; Animals; Brain; Caffeine; Environmental Pollutants; Female; Gene Deletion; Lactation; Male; M | 2007 |
Intrauterine exposures and risk of endometriosis.
Topics: Adolescent; Adult; Alcohol Drinking; Caffeine; Cimicifuga; Endometriosis; Female; Humans; Laparoscop | 2007 |
Maternal caffeine administration and cerebral oxygenation in near-term fetal sheep.
Topics: Animals; Blood Flow Velocity; Brain; Caffeine; Central Nervous System Stimulants; Cerebrovascular Ci | 2007 |
Maternal smoking, alcohol consumption, and caffeine consumption during pregnancy in relation to a son's risk of persistent cryptorchidism: a prospective study in the Child Health and Development Studies cohort, 1959-1967.
Topics: Alcohol Drinking; Analysis of Variance; Caffeine; Coffee; Cryptorchidism; Ethanol; Female; Humans; I | 2008 |
Prenatal caffeine assessment: fetal and maternal biomarkers or self-reported intake?
Topics: Adult; Biomarkers; Caffeine; Connecticut; Female; Fetal Blood; Humans; Massachusetts; Maternal-Fetal | 2008 |
Caffeine and miscarriage risk.
Topics: Abortion, Spontaneous; Adolescent; Adult; Caffeine; Coffee; Female; Humans; Interviews as Topic; Mid | 2008 |
Maternal caffeine consumption during pregnancy and the risk of miscarriage: a prospective cohort study.
Topics: Abortion, Spontaneous; Adult; Beverages; Caffeine; Female; Humans; Pregnancy; Prospective Studies; R | 2008 |
Assessing caffeine exposure in pregnant women.
Topics: Adult; Biomarkers; Caffeine; Diet Records; Feeding Behavior; Female; Humans; Pregnancy; Pregnancy Ou | 2008 |
Modest maternal caffeine exposure affects developing embryonic cardiovascular function and growth.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Aorta; Blood Flow Vel | 2008 |
Control of nuclear remodelling and subsequent in vitro development and methylation status of porcine nuclear transfer embryos.
Topics: Animals; Apoptosis; Caffeine; Cell Nucleus; Cellular Reprogramming; Cleavage Stage, Ovum; DNA Methyl | 2008 |
Protein-energy malnutrition during pregnancy alters caffeine's effect on brain tissue of neonate rats.
Topics: Adult; Animals; Animals, Newborn; Body Weight; Brain; Brain Chemistry; Caffeine; DNA; Female; Guinea | 1984 |
Central adenosine receptors: possible involvement in the chronic effects of caffeine.
Topics: Animals; Brain; Caffeine; Diet; Female; Mice; Pregnancy; Receptors, Cell Surface; Receptors, Puriner | 1984 |
Coffee in pregnancy.
Topics: Caffeine; Coffee; Congenital Abnormalities; Female; Humans; Maternal-Fetal Exchange; Pregnancy; Smok | 1981 |
Effects of methylxanthines on lipid synthesis in developing neural systems.
Topics: Acetyl-CoA Carboxylase; Aging; Aminophylline; Brain; Caffeine; Cell Division; Cell Line; Cholesterol | 1981 |
Caffeine in pregnancy.
Topics: Caffeine; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy | 1982 |
Effect of some drugs, experimental stress and estrus on unstable and fixed conditioned alimentary motor reflexes in cats. Part II.
Topics: Amphetamine; Animals; Barbiturates; Caffeine; Cats; Chlorprothixene; Conditioning, Classical; Diazep | 1983 |
Changing trends in drug use during pregnancy.
Topics: Adolescent; Adult; Alcohol Drinking; Analgesics; Antacids; Antiemetics; Appetite Depressants; Caffei | 1982 |
Adverse effect of maternal caffeine ingestion on fetal cerebrum in rat.
Topics: Animals; Brain; Brain Chemistry; Caffeine; DNA; Female; Fetal Proteins; Maternal-Fetal Exchange; Ner | 1983 |
Effect of some drugs, experimental stress and estrus on unstable and fixed conditioned alimentary motor reflexes in cats.
Topics: Amphetamine; Animals; Barbiturates; Behavior, Animal; Caffeine; Cats; Chlorprothixene; Conditioning, | 1982 |
Participation of the sarcolemma in the control of relaxation of the mammalian heart during perinatal development.
Topics: Animals; Caffeine; Calcium; Cell Differentiation; Female; Ion Channels; Muscle Contraction; Muscle R | 1982 |
Effects of chronic caffeine on brain adenosine receptors: regional and ontogenetic studies.
Topics: Adenosine; Animals; Brain; Brain Stem; Caffeine; Cerebellum; Female; Male; Mice; Pregnancy; Prenatal | 1984 |
In vitro and in vivo displacement of [3H]-diazepam binding by purine derivatives in developing rat brain.
Topics: Animals; Binding, Competitive; Brain; Caffeine; Diazepam; Female; In Vitro Techniques; Kinetics; Mal | 1984 |
The synergistic effects of radiation and caffeine on embryonic development in mice.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Caffeine; Embryonic and Feta | 1984 |
The treatment of the asthmatic mother during pregnancy and lactation.
Topics: Adrenal Cortex Hormones; Asthma; Bronchodilator Agents; Caffeine; Cromolyn Sodium; Ethanol; Female; | 1983 |
Antiteratogenic effects of tumor inhibitors, caffeine, antipain, and retinoic acid in mice.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antipain; Caffeine; Carcinogens; Ethylnitrosourea; Female; Fetus; | 1983 |
Potentiating effects of caffeine on teratogenicity of alkylating agents in mice.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Alkylating Agents; Animals; Antibioti | 1983 |
Influences of maternal caffeine on the neonatal rat brains vary with the nutritional states.
Topics: Animals; Animals, Newborn; Brain; Caffeine; Dietary Proteins; Female; Lactation; Nerve Tissue Protei | 1983 |
Potentiating effects of methylxanthines on teratogenicity of mitomycin C in mice.
Topics: Abnormalities, Drug-Induced; Animals; Antibiotics, Antineoplastic; Caffeine; Drug Synergism; Female; | 1983 |
Six-hydroxydopamine induced hyperactivity: neither sex differences nor caffeine stimulation are found.
Topics: Aging; alpha-Methyltyrosine; Animals; Body Weight; Brain; Brain Chemistry; Caffeine; Catecholamines; | 1984 |
Effects of caffeine on the growth of mandible and long bone in protein-energy malnourished newborn rats.
Topics: Animals; Body Weight; Bone and Bones; Caffeine; Calcium; Collagen; Female; Hydroxyproline; Organ Siz | 1984 |
Long-lasting tolerance to stimulatory effects of perinatal caffeine treatment.
Topics: Animals; Caffeine; Drug Tolerance; Female; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effe | 1984 |
Potentiative interactions between caffeine and various teratogenic agents.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Animals; Caffeine; Cycloheximide; Dactinomycin; Dose-Res | 1982 |
Infant size at 8 months of age: relationship to maternal use of alcohol, nicotine, and caffeine during pregnancy.
Topics: Alcohol Drinking; Body Weight; Caffeine; Cannabis; Female; Head; Humans; Infant; Male; Maternal-Feta | 1984 |
Caffeine and its dimethylxanthines and fetal cerebral development in rat.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Caffeine; Female; Fetus; Maternal-Fetal Exchange; Pregn | 1984 |
Caffeine, theophylline and theobromine in pregnancy.
Topics: Caffeine; Female; Humans; Pregnancy; Theobromine; Theophylline | 1984 |
Improved micro-method for the high-performance liquid chromatographic determination of caffeine and paraxanthine in biological fluids.
Topics: Animals; Body Fluids; Caffeine; Chromatography, High Pressure Liquid; Female; Fetal Blood; Pregnancy | 1984 |
Maternal coffee drinking and unusually high concentrations of caffeine in the newborn.
Topics: Apnea; Caffeine; Coffee; Female; Half-Life; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; | 1984 |
Effect of aminophylline and caffeine on total and surfactant phospholipid in fetal rabbit lung.
Topics: Aminophylline; Animals; Caffeine; Female; Fetal Blood; Lung; Organ Size; Phosphatidylcholines; Phosp | 1984 |
[Interference between fetal distress and administration of drugs].
Topics: Alcohol Drinking; Caffeine; Drug-Related Side Effects and Adverse Reactions; Female; Fetal Distress; | 1983 |
Pharmacokinetics of caffeine during and after pregnancy.
Topics: Adult; Caffeine; Female; Humans; Kinetics; Postpartum Period; Pregnancy; Regression Analysis | 1983 |
Coffee consumption during pregnancy and selected congenital malformations: a nationwide case-control study.
Topics: Abnormalities, Drug-Induced; Caffeine; Coffee; Female; Finland; Humans; Pilot Projects; Pregnancy; R | 1983 |
The effect of caffeine on placental and fetal blood flow in human pregnancy.
Topics: Blood Pressure; Caffeine; Epinephrine; Female; Fetal Blood; Humans; Hypertension; Placenta; Pregnanc | 1983 |
[Relationship between the placental-fetal index (PFI) and the toxic and teratogenic effect in the fetuses of mothers treated with sedalgin during pregnancy].
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Caffeine; Codeine; Drug Combinations; Female; Fetus; | 1983 |
Caffeine-induced limb malformations: description of malformations and quantitation of placental transfer.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Dose-Response Relationship, Drug; Female; Limb Defor | 1983 |
Fetal breathing movements. An update for the pediatrician.
Topics: Anesthesia, General; Animals; Barbiturates; Caffeine; Central Nervous System; Circadian Rhythm; Fema | 1983 |
A study of the teratogenic potential of caffeine ingested in drinking-water.
Topics: Animals; Body Weight; Bone and Bones; Caffeine; Dose-Response Relationship, Drug; Female; Fetal Reso | 1983 |
Drugs in the food supply.
Topics: Abnormalities, Drug-Induced; Animals; Behavior; Caffeine; Female; Food Additives; Food Supply; Human | 1983 |
Disposition of dietary caffeine in milk, saliva, and plasma of lactating women.
Topics: Adult; Caffeine; Female; Humans; Infant; Infant, Newborn; Intestinal Absorption; Lactation; Milk, Hu | 1984 |
Behavioral and physical development of rats chronically exposed to caffeinated fluids.
Topics: Animals; Behavior, Animal; Caffeine; Coffee; Female; Growth; Male; Pregnancy; Prenatal Exposure Dela | 1984 |
The toxicology of chemical interactions during pregnancy in the mouse: caffeine and phenytoin.
Topics: Animals; Caffeine; Drug Interactions; Female; Fetal Death; Fetal Resorption; Mice; Mice, Inbred ICR; | 1984 |
Effects of ethanol and/or caffeine on fetal development and placental amino acid uptake in rats.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Birth Weight; Body Weight; Caffeine; Diet; Ethanol; Fem | 1984 |
Blood flow changes and conceptal development in pregnant rats in response to caffeine.
Topics: Animals; Caffeine; Embryo, Mammalian; Female; Fetus; Organ Size; Ovary; Placenta; Pregnancy; Rats; R | 1984 |
Maternal-fetal transfer of aminophylline.
Topics: Aminophylline; Amniotic Fluid; Caffeine; Cesarean Section; Chromatography, High Pressure Liquid; Fem | 1984 |
Two-year toxicity/carcinogenicity study of fresh-brewed coffee in rats initially exposed in utero.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Bone and Bones; Caffeine; Calcium; Carcinogens; F | 1984 |
Estimation of creatine kinase isoenzymes: the effects of caffeine and retinoic acid on CK levels in fetal mouse limbs.
Topics: Animals; Caffeine; Chromatography, DEAE-Cellulose; Creatine Kinase; Electrophoresis, Cellulose Aceta | 1984 |
Caffeine labeling. Council on Scientific Affairs. American Medical Association.
Topics: Abnormalities, Drug-Induced; Behavior; Cacao; Caffeine; Carbonated Beverages; Coffee; Female; Fibroc | 1984 |
Maternal drinking behavior and decreased intrauterine growth.
Topics: Adult; Alcohol Drinking; Birth Weight; Caffeine; Female; Fetal Growth Retardation; Humans; Maternal- | 1982 |
The effect of maternal caffeine ingestion on pancreatic function in the neonatal rat.
Topics: Animals; Animals, Newborn; Caffeine; Dose-Response Relationship, Drug; Female; Glucose; In Vitro Tec | 1982 |
Timing of chemically induced neoplasia in mice revealed by the antineoplastic action of caffeine.
Topics: 4-Nitroquinoline-1-oxide; Animals; Caffeine; DNA Repair; Ethylnitrosourea; Female; Hydroxamic Acids; | 1980 |
Gestational caffeine modifies offspring behaviour in mice.
Topics: Animals; Avoidance Learning; Behavior, Animal; Caffeine; Dextroamphetamine; Dopamine; Female; Male; | 1981 |
Jejunal atresia associated with Cafergot ingestion during pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Caffeine; Drug Combinations; Ergotamine; Female; Humans; Infant, | 1983 |
Pharmacokinetic and hemodynamic effects of caffeine in the pregnant sheep.
Topics: Acid-Base Equilibrium; Animals; Caffeine; Female; Fetus; Hemodynamics; Hydrogen-Ion Concentration; K | 1983 |
Rescue from disproportionate dwarfism in mice by means of caffeine modulation of the 4-hour early effect of excessive vitamin A.
Topics: Animals; Caffeine; Cell Aggregation; DNA; Dwarfism; Extremities; Female; Glycolipids; Mice; Pregnanc | 1983 |
Maternal cardiovascular response to caffeine infusion in the pregnant ewe.
Topics: Animals; Blood Flow Velocity; Caffeine; Female; Fetal Blood; Fetal Hypoxia; Oxygen; Pregnancy; Sheep | 1983 |
The interaction of chemicals during pregnancy: an update.
Topics: Abnormalities, Drug-Induced; Animals; Bromodeoxyuridine; Caffeine; Drug Interactions; Female; Fetus; | 1983 |
Placental transfer of the major caffeine metabolite in the rat using 6-amino-5[N-formylmethylamino]1,3[Me-14C]-dimethyluracil administered orally or intravenously to the pregnant rat.
Topics: Administration, Oral; Animals; Autoradiography; Caffeine; Feces; Female; Injections, Intravenous; Ma | 1983 |
Drug-induced changes in fetal breathing activity and sleep state.
Topics: Animals; Caffeine; Doxapram; Female; Fetus; Indomethacin; Pilocarpine; Pregnancy; Respiration; Sheep | 1983 |
Pre- and postnatal effects of caffeine on brain biogenic amines, cyclic nucleotides and behavior in developing rats.
Topics: Animals; Animals, Newborn; Behavior, Animal; Biogenic Amines; Body Weight; Brain Chemistry; Caffeine | 1983 |
Food and malformation.
Topics: Abnormalities, Drug-Induced; Caffeine; Congenital Abnormalities; Female; Fetal Alcohol Spectrum Diso | 1982 |
Caffeine and pregnancy: answers to common questions.
Topics: Animals; Caffeine; Coffee; Female; Fetus; Humans; Pregnancy; Rats | 1981 |
Caffeine: how serious a health menace?
Topics: Caffeine; Female; Humans; Pregnancy; United States; United States Food and Drug Administration | 1981 |
The effect of pregnancy on the pharmacokinetics of caffeine.
Topics: Caffeine; Female; Half-Life; Humans; Kinetics; Male; Pregnancy | 1982 |
Effects of maternal alcohol, nicotine, and caffeine use during pregnancy on infant mental and motor development at eight months.
Topics: Adolescent; Adult; Alcohol Drinking; Alcoholism; Caffeine; Child Development; Ethanol; Female; Human | 1980 |
Apnea associated with theophylline withdrawal in a term neonate.
Topics: Apnea; Caffeine; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange | 1982 |
Placental theophylline transfer in pregnant asthmatics.
Topics: Adolescent; Adult; Asthma; Caffeine; Female; Fetal Blood; Fetus; Half-Life; Heart; Hemodynamics; Hum | 1982 |
Metabolism and distribution of labeled theophylline in the pregnant rat. Impairment of theophylline metabolism by pregnancy and absence of a blood-brain barrier in the fetus.
Topics: Animals; Blood-Brain Barrier; Brain Chemistry; Caffeine; Female; Fetus; Maternal-Fetal Exchange; Pre | 1982 |
Coffee consumption during pregnancy: subsequent behavioral abnormalities of the offspring.
Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Caffeine; Coffee; Female; Fetus; Male; Org | 1982 |
Coffee consumption during pregnancy.
Topics: Caffeine; Carbonated Beverages; Coffee; Congenital Abnormalities; Female; Humans; Infant, Newborn; P | 1982 |
An alternative treatment for spinal headache.
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Benzoates; Caffeine; Drug Combinations; Female; | 1982 |
Studies on the teratogenic effects of different oral preparations of caffeine in mice.
Topics: Animals; Bone and Bones; Caffeine; Delayed-Action Preparations; Female; Mice; Pregnancy; Pregnancy, | 1982 |
Seizures associated with a new combination "pick-me-up" pill.
Topics: Adolescent; Caffeine; Drug Combinations; Ephedrine; Female; Humans; Phenylpropanolamine; Pregnancy; | 1982 |
Delayed elimination of caffeine by women in the last 2 weeks of pregnancy.
Topics: Adult; Caffeine; Female; Humans; Infant, Newborn; Kinetics; Maternal-Fetal Exchange; Postpartum Peri | 1982 |
Offspring effects and pregnancy complications related to self-reported maternal alcohol use.
Topics: Abnormalities, Drug-Induced; Alcohol Drinking; Apgar Score; Caffeine; Female; Fetus; Heart Rate; Hum | 1982 |
In vivo fertilization after initiation of sperm motility in the hamster epididymis.
Topics: Animals; Caffeine; Cricetinae; Epididymis; Female; Fertilization; Insemination, Artificial; Male; Pr | 1982 |
Activation and odor conditioning of suckling behavior in 3-day-old albino rats.
Topics: Animals; Animals, Newborn; Association Learning; Body Temperature Regulation; Caffeine; Conditioning | 1982 |
Blood levels of caffeine and results of fetal examination after oral administration of caffeine to pregnant rats.
Topics: Administration, Oral; Animals; Caffeine; Female; Fetus; Maternal-Fetal Exchange; Pregnancy; Rats; Ra | 1982 |
The effect of brewed and instant coffee on reproduction and teratogenesis in the rat.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Bone and Bones; Caffeine; Coffee; Female; Fetal D | 1981 |
Increased sleep time in the offspring of caffeine-treated dams from two inbred strains of mice.
Topics: Animals; Caffeine; Female; Gestational Age; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred Strain | 1981 |
Caffeine and the fetus: is trouble brewing?
Topics: Animals; Caffeine; Female; Fetus; Humans; Maternal-Fetal Exchange; Pregnancy; Rats | 1981 |
Adverse effects of caffeine.
Topics: Caffeine; Carcinogens; Female; Heart; Humans; Pregnancy; Psychology | 1981 |
The effects of maternal carbohydrate (sucrose) supplementation on the growth of offspring of pregnancies with habitual caffeine consumption.
Topics: Animals; Animals, Newborn; Blood Glucose; Body Weight; Caffeine; Dietary Carbohydrates; Female; Male | 1981 |
Effect of caffeine on rat offspring from treated dams.
Topics: Animals; Birth Weight; Caffeine; Female; Fetus; Milk; Pregnancy; Rats; Rats, Inbred Strains | 1980 |
Effects of maternal caffeine ingestion on neonatal growth in rats.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Birth Weight; Body Weight; Caffeine; Female; | 1981 |
Caffeine ingestion during pregnancy: in utero exposure and possible effects.
Topics: Aminophylline; Animals; Beverages; Caffeine; Carcinogens; Delivery, Obstetric; Female; Fetus; Humans | 1981 |
The disposition of caffeine during and after pregnancy.
Topics: Adult; Caffeine; Female; Humans; Kinetics; Postpartum Period; Pregnancy; Pregnancy Trimester, First; | 1981 |
Conversion of theophylline to caffeine by the human fetus.
Topics: Amniotic Fluid; Caffeine; Female; Fetal Blood; Fetus; Humans; Infant, Newborn; Infant, Premature; Ma | 1981 |
Excretion of methylxanthines in human milk.
Topics: Adult; Beverages; Caffeine; Child, Preschool; Chromatography, High Pressure Liquid; Female; Humans; | 1981 |
Effect of pregnancy on the pharmacokinetics of caffeine.
Topics: Adult; Caffeine; Female; Half-Life; Humans; Kinetics; Male; Pregnancy; Smoking | 1981 |
Caffeine: an update.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Animals; Behavior; Caffeine; Child; Child, Preschool | 1981 |
Acute studies to investigate the mechanism of action of caffeine as a teratogen in mice.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex; Amniotic Fluid; Animals; Caffeine; Cleft Palate; Cortic | 1981 |
Caffeine study.
Topics: Abnormalities, Drug-Induced; Caffeine; Female; Humans; Infant, Newborn; Pregnancy; Teratogens | 1980 |
Brain catecholamines and sleep states in offspring of caffeine-treated rats.
Topics: Animals; Brain; Caffeine; Dopamine; Female; Locus Coeruleus; Male; Maternal-Fetal Exchange; Norepine | 1980 |
Caffeine and pregnancy.
Topics: Caffeine; Female; Humans; Pregnancy; United States; United States Food and Drug Administration | 1980 |
The effect of long term caffeine treatment on hypoxic-ischemic brain damage in the neonate.
Topics: Animals; Animals, Newborn; Brain; Brain Ischemia; Caffeine; Central Nervous System Stimulants; Femal | 1995 |
Effects of caffeine consumption on delayed conception.
Topics: Adult; Caffeine; Coffee; Female; Fertilization; Humans; New York; Odds Ratio; Pregnancy; Proportiona | 1995 |
The effect of caffeine on mammary gland development and milk yield in primiparous sows.
Topics: Aging; Animals; Animals, Suckling; Birth Weight; Caffeine; DNA; Eating; Female; Lactation; Mammary G | 1995 |
Isolation and partial cloning of ryanodine-sensitive Ca2+ release channel protein isoforms from human myometrial smooth muscle.
Topics: Amino Acid Sequence; Animals; Base Sequence; Caffeine; Calcium; Calcium Channels; Calmodulin-Binding | 1995 |
Correlation of prenatal events with the development of polymicrogyria.
Topics: Abnormalities, Drug-Induced; Brain; Caffeine; Cerebral Cortex; Child; Child, Preschool; Ergotamine; | 1995 |
Effects of caffeine intake during gestation and lactation on the acid solubility of enamel in weanling rats.
Topics: Animals; Animals, Newborn; Caffeine; Calcium; Dental Enamel; Dental Enamel Solubility; Female; Lacta | 1995 |
Preterm delivery: effects of socioeconomic factors, psychological stress, smoking, alcohol, and caffeine.
Topics: Alcohol Drinking; Body Height; Caffeine; Cluster Analysis; Coffee; Educational Status; Female; Follo | 1995 |
Caffeine, health and commercial interests.
Topics: Caffeine; Female; Humans; Infant, Newborn; Peer Review; Pregnancy; Prenatal Exposure Delayed Effects | 1995 |
Spontaneous abortion in a hospital population: are tobacco and coffee intake risk factors?
Topics: Abortion, Spontaneous; Adult; Age Factors; Alcohol Drinking; Caffeine; Case-Control Studies; Coffee; | 1994 |
Maternal smoking, alcohol drinking, caffeine consumption, and fetal growth: results from a prospective study.
Topics: Adult; Alcohol Drinking; Birth Weight; Caffeine; Coffee; Embryonic and Fetal Development; Ethanol; F | 1995 |
Role of nitric oxide on vasorelaxation in human umbilical artery.
Topics: Caffeine; Calcimycin; Calcium; Cyclic GMP; Female; Histamine; Humans; In Vitro Techniques; Nitric Ox | 1995 |
Effects of prenatal exposure to alcohol plus caffeine in rats: pregnancy outcome and early offspring development.
Topics: Animals; Body Weight; Caffeine; Drug Synergism; Ethanol; Female; Fetal Alcohol Spectrum Disorders; G | 1995 |
Panic disorder in pregnancy.
Topics: Adult; Breast Feeding; Caffeine; Female; Humans; Middle Aged; Panic Disorder; Parity; Pregnancy; Pre | 1994 |
Immature maxi-K channels exhibit heterogeneous properties in the embryonic rat telencephalon.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arachidonic Acid; Caffeine; Calcimycin; Cyclic GMP; | 1994 |
Hypokalemia in a pregnant woman with long-term heavy cola consumption.
Topics: Adult; Beverages; Caffeine; Female; Humans; Hypokalemia; Pregnancy; Pregnancy Complications; Time Fa | 1994 |
Re: "Association of delayed conception with caffeine consumption".
Topics: Caffeine; Female; Fertilization; Humans; Pregnancy; Time Factors | 1994 |
In vitro study of teratogenic effects of caffeine on cultured rat embryos and embryonic cells.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Cell Differentiation; Cell Division; Cells, Cultured | 1994 |
Some mechanical properties of skinned fibres of pregnant human myometrium.
Topics: Adult; Biomechanical Phenomena; Caffeine; Calcium; Calmodulin; Cell Membrane Permeability; Dinoprost | 1994 |
Fetal loss and caffeine intake.
Topics: Abortion, Spontaneous; Caffeine; Female; Humans; Pregnancy | 1994 |
Fetal loss and caffeine intake.
Topics: Abortion, Spontaneous; Caffeine; Female; Humans; Pregnancy | 1994 |
Fetal loss and caffeine intake.
Topics: Abortion, Spontaneous; Caffeine; Case-Control Studies; Female; Humans; Pregnancy | 1994 |
Interaction of dimethylsulfoxide and arachidonic acid with the teratogenic effects of caffeine in mice.
Topics: Abnormalities, Drug-Induced; Animals; Arachidonic Acid; Caffeine; Cleft Palate; Corticosterone; Dime | 1994 |
Alteration of femoral structure in later life by chronically feeding caffeine during rapid growing period in newborn female rats.
Topics: Animals; Bone and Bones; Bone Density; Bone Development; Caffeine; Female; Femur; Mandible; Pregnanc | 1994 |
Symptoms and health problems in pregnancy: their association with social factors, smoking, alcohol, caffeine and attitude to pregnancy.
Topics: Alcohol Drinking; Attitude; Caffeine; Female; Humans; London; Pregnancy; Pregnancy Complications; Pr | 1994 |
Cigarette smoking, alcohol consumption, and caffeine intake and fecundability.
Topics: Adolescent; Adult; Alcohol Drinking; Caffeine; Female; Fertility; Health Behavior; Humans; Life Styl | 1994 |
Coffee, cardiac disease, cancer and common sense.
Topics: Animals; Caffeine; Coffee; Coronary Disease; Female; Humans; Neoplasms; Pregnancy; Pregnancy Complic | 1994 |
Combined effects of caffeine and malnutrition during pregnancy on suckling behavior in newborn rats.
Topics: Animals; Body Weight; Caffeine; Dose-Response Relationship, Drug; Female; Fetal Movement; Gestationa | 1994 |
Several genetic and environmental factors influence cord blood IgE concentration.
Topics: Alcohol Drinking; Birth Weight; Caffeine; Female; Fetal Blood; Humans; Hypersensitivity, Immediate; | 1994 |
In utero caffeine exposure affects feeding pattern and variable ratio performance in infant monkeys.
Topics: Animals; Animals, Newborn; Caffeine; Feeding Behavior; Female; Macaca fascicularis; Pregnancy; Prena | 1994 |
Seventh International Caffeine Workshop, Santorini, Greece 13-17 June 1993.
Topics: Adolescent; Adult; Bone Density; Caffeine; Calcium; Carbonated Beverages; Cardiovascular Diseases; C | 1994 |
Alteration in the tissue retention of [14C]-caffeine in pregnant mice by dimethylsulfoxide.
Topics: Animals; Caffeine; Dimethyl Sulfoxide; Female; Mice; Pregnancy; Pregnancy, Animal; Tissue Distributi | 1993 |
Effects of chronic caffeine feeding on the activities of oxygen free radical defense enzymes in the growing rat heart and liver.
Topics: Aging; Animals; Caffeine; Catalase; Copper; Female; Glutathione Peroxidase; Heart; Iron; Liver; Myoc | 1994 |
Acute maternal and fetal cardiovascular effects of caffeine ingestion.
Topics: Adult; Aorta; Blood Flow Velocity; Blood Pressure; Caffeine; Female; Fetal Heart; Heart Rate; Heart | 1994 |
Relation between rate of cell proliferation and formation of micronuclei after combined treatment with X-rays and caffeine.
Topics: Animals; Blastocyst; Caffeine; Cell Division; Female; Mice; Micronuclei, Chromosome-Defective; Micro | 1993 |
Use of chaos theory and complex systems modeling to study alcohol effects on fetal condition.
Topics: Alcohol Drinking; Caffeine; Cannabis; Cocaine; Computer Simulation; Female; Fetus; Heroin; Humans; M | 1993 |
Accumulation of theophylline, theobromine and paraxanthine in the fetal rat brain following a single oral dose of caffeine.
Topics: Animals; Biotransformation; Brain; Caffeine; Chromatography, High Pressure Liquid; Female; Pregnancy | 1993 |
Association of delayed conception with caffeine consumption.
Topics: Beverages; Caffeine; Cross-Sectional Studies; Female; Fertilization; Humans; Pregnancy; Statistics a | 1993 |
Immunohistochemical localisation of the 90, 70 and 25 kDa heat shock proteins in control and caffeine treated rat embryos.
Topics: Animals; Caffeine; Embryo, Mammalian; Female; Heart; Heat-Shock Proteins; Immunohistochemistry; Mate | 1993 |
Effects of birth weight of alcohol and caffeine consumption during pregnancy.
Topics: Birth Weight; Caffeine; Ethanol; Female; Gestational Age; Humans; Infant, Newborn; Maternal Age; Mat | 1993 |
Relation of caffeine intake during pregnancy to intrauterine growth retardation and preterm birth.
Topics: Adult; Birth Weight; Cacao; Caffeine; Coffee; Educational Status; Female; Fetal Growth Retardation; | 1993 |
Invited commentary: caffeine and birth outcomes.
Topics: Birth Weight; Caffeine; Confounding Factors, Epidemiologic; Female; Fetal Growth Retardation; Gestat | 1993 |
The effect of prenatal caffeine exposure on the enamel surface of the first molars of newborn rats.
Topics: Animals; Animals, Newborn; Caffeine; Calcium; Dental Enamel; Dental Enamel Solubility; Drug Implants | 1993 |
Placental transfer and foetal disposition of caffeine and its immediate metabolites in the 20-day pregnant rat: function of dose.
Topics: Amniotic Fluid; Animals; Biotransformation; Caffeine; Female; Fetus; Half-Life; Maternal-Fetal Excha | 1993 |
Caffeine use during pregnancy: how much is safe?
Topics: Caffeine; Coffee; Embryonic and Fetal Development; Female; Humans; Pregnancy; Pregnancy Outcome | 1993 |
Java jive.
Topics: Bias; Caffeine; Chromosome Aberrations; Chromosome Disorders; Female; Humans; Pregnancy; Pregnancy O | 1993 |
Modulation of sarcoplasmic reticulum Ca(2+)-release channels by caffeine, Ca2+, and Mg2+ in skinned myocardial fibers of fetal and adult rats.
Topics: Animals; Caffeine; Calcium; Calcium Channels; Dose-Response Relationship, Drug; Female; Heart; Magne | 1993 |
Newborn cardiac arrhythmias associated with maternal caffeine use during pregnancy.
Topics: Arrhythmias, Cardiac; Caffeine; Coffee; Female; Humans; Infant, Newborn; Pregnancy; Prenatal Exposur | 1993 |
Moderate caffeine use and the risk of spontaneous abortion and intrauterine growth retardation.
Topics: Abortion, Spontaneous; Adult; Caffeine; Cohort Studies; Embryonic and Fetal Development; Female; Fet | 1993 |
Proliferation-associated increase in sensitivity of mammary epithelial cells to inositol-1,4,5-trisphosphate.
Topics: Animals; Caffeine; Calcium; Cell Division; Cells, Cultured; Drug Resistance; Epidermal Growth Factor | 1993 |
Maternal caffeine consumption and fetal behavior in normal third-trimester pregnancy.
Topics: Adult; Caffeine; Eye Movements; Female; Fetal Movement; Fetus; Health Behavior; Heart Rate, Fetal; H | 1993 |
Acetazolamide with caffeine causes exencephaly in "resistant" SWV mice.
Topics: Acetazolamide; Animals; Birth Weight; Brain; Caffeine; Cervical Vertebrae; Embryo, Mammalian; Female | 1993 |
Caffeine effects on meiotic maturation in hamster oocytes in vitro.
Topics: Animals; Caffeine; Cricetinae; Female; Meiosis; Oocytes; Pregnancy | 1993 |
Caffeine use during pregnancy: how much is safe?
Topics: Caffeine; Coffee; Female; Humans; Pregnancy; Pregnancy Outcome | 1993 |
Combined effects of caffeine and malnutrition on the development of the trigeminal nuclear center: autoradiographic and biochemical studies.
Topics: Animals; Autoradiography; Caffeine; Cholesterol; DNA Replication; Dose-Response Relationship, Drug; | 1995 |
Effects of diazepam and cyclohexyladenosine on open-field behavior in rats perinatally exposed to caffeine.
Topics: Adenosine; Animals; Caffeine; Diazepam; Eliminative Behavior, Animal; Emotions; Female; Grooming; Lo | 1996 |
Identification of three isoforms of the InsP3 receptor in human myometrial smooth muscle.
Topics: Base Sequence; Caffeine; Calcium; Calcium Channels; Cells, Cultured; Female; Heparin; Humans; Inosit | 1996 |
Comet assay studies indicate that caffeine-mediated increase in radiation risk of embryos is due to inhibition of DNA repair.
Topics: Animals; Caffeine; Central Nervous System Stimulants; DNA; DNA Damage; DNA Repair; Embryo, Mammalian | 1996 |
Endothelin-induced contractions in human placental blood vessels are enhanced in intrauterine growth retardation, and modulated by agents that regulate levels of intracellular calcium.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Lifestyle and risk of premature sexual activity in a high school population of Seventh-Day Adventists: Valuegenesis 1989.
Topics: Adolescent; Adolescent Behavior; Age Distribution; Alcohol Drinking; Caffeine; Christianity; Databas | 1996 |
Maternal caffeine consumption and spontaneous abortion: a prospective cohort study.
Topics: Abortion, Spontaneous; Adult; Caffeine; Causality; Connecticut; Cross-Sectional Studies; Dose-Respon | 1996 |
Smoking during pregnancy and preterm birth.
Topics: Adolescent; Adult; Body Height; Body Weight; Caffeine; Female; Follow-Up Studies; Gestational Age; H | 1996 |
Assays for CYP1A2 by testing in vivo metabolism of caffeine in humans.
Topics: Adolescent; Adult; Aged; Caffeine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cy | 1996 |
Motility, acrosome integrity and fertility of frozen ram spermatozoa treated with caffeine, pentoxifylline, cAMP, 2-deoxyadenosine and kallikrein.
Topics: Acrosome; Animals; Caffeine; Cryopreservation; Cyclic AMP; Deoxyadenosines; Female; Fertilization; K | 1995 |
Combined effects of caffeine and alcohol during pregnancy on bones in newborn rats.
Topics: Animals; Animals, Newborn; Caffeine; Calcium; Central Nervous System Depressants; Central Nervous Sy | 1996 |
Autism, Asperger's syndrome and the Crick-Mitchison theory of the biological function of REM sleep.
Topics: Autistic Disorder; Brain; Caffeine; Female; Fetus; Humans; Infant; Infant, Newborn; Models, Neurolog | 1996 |
Relation of caffeine intake and blood caffeine concentrations during pregnancy to fetal growth: prospective population based study.
Topics: Beverages; Birth Weight; Cacao; Caffeine; Carbonated Beverages; Coffee; Drinking; Embryonic and Feta | 1996 |
Effect of dietary caffeine and zinc on the activity of antioxidant enzymes, zinc, and copper concentration of the heart and liver in fast-growing rats.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Copper; Diet; Female; Glutathione Peroxidase; | 1995 |
Demonstration of congenital anomalies in the joints of the forelimbs and hindlimbs caused by several pharmacological agents.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agen | 1996 |
Neonatal caffeine alters passive avoidance retention in rats in an age- and gender-related manner.
Topics: Age Factors; Animals; Animals, Newborn; Avoidance Learning; Caffeine; Central Nervous System Stimula | 1997 |
Caffeine intake and delayed conception: a European multicenter study on infertility and subfecundity. European Study Group on Infertility Subfecundity.
Topics: Adult; Caffeine; Central Nervous System Stimulants; Coffee; Diet Surveys; Europe; Female; Humans; In | 1997 |
Effect of caffeine intake during pregnancy on birth weight.
Topics: Birth Weight; Caffeine; Case-Control Studies; Central Nervous System Stimulants; Coffee; Confounding | 1997 |
Reproductive toxicology. Caffeine.
Topics: Alopecia; Animals; Caffeine; Dose-Response Relationship, Drug; Female; Litter Size; Liver; Male; Mic | 1997 |
Reproductive toxicology. Caffeine.
Topics: Animals; Birth Weight; Body Weight; Caffeine; Dose-Response Relationship, Drug; Female; Litter Size; | 1997 |
[Maternal environment and developmental brain damages].
Topics: Animals; Brain; Brain Damage, Chronic; Caffeine; Dogs; Female; Fetal Alcohol Spectrum Disorders; Hum | 1997 |
Comparative effects of age and chronic low-level lead exposure on calcium mobilization from intracellular calcium stores in brain samples obtained from the neonatal and the adult rats.
Topics: Age Factors; Animals; Animals, Newborn; Binding Sites; Brain Chemistry; Caffeine; Calcium; Cell Memb | 1997 |
Postnatal caffeine effects on copper, zinc, and iron concentrations in mammary gland, milk, and plasma of lactating dams and their offspring.
Topics: Animals; Animals, Newborn; Caffeine; Cations; Copper; Female; Iron; Mammary Glands, Animal; Milk; Po | 1997 |
[Caffeine and children].
Topics: Adolescent; Adult; Beverages; Cacao; Caffeine; Child; Child, Preschool; Dose-Response Relationship, | 1997 |
Effects of cigarette smoking, caffeine consumption, and alcohol intake on fecundability.
Topics: Adult; Alcohol Drinking; Caffeine; Female; Humans; Infertility, Female; Male; Ontario; Pregnancy; Re | 1997 |
Caffeinated beverages, decaffeinated coffee, and spontaneous abortion.
Topics: Abortion, Spontaneous; Adult; Beverages; Bias; Caffeine; California; Coffee; Female; Humans; Odds Ra | 1997 |
Nicotine and caffeine. Influence on prenatal hemodynamics and behavior in early twin pregnancy.
Topics: Adult; Caffeine; Female; Fetal Movement; Heart Rate, Fetal; Hemodynamics; Humans; Male; Nicotine; Pi | 1997 |
Caffeine-induced disturbances of early neurogenesis in whole mouse embryo cultures.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Embryo, Mammalian; Embryonic and Fetal Development; | 1997 |
[The effect of mothers' occupation on body mass of newborns born at term].
Topics: Abortion, Spontaneous; Adult; Birth Weight; Caffeine; Female; Health Status; Humans; Incidence; Infa | 1997 |
[Smoking during pregnancy and preterm delivery].
Topics: Adolescent; Adult; Caffeine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; In | 1998 |
Serum caffeine and paraxanthine as markers for reported caffeine intake in pregnancy.
Topics: Biomarkers; Blood Specimen Collection; Caffeine; Cohort Studies; Diet; Female; Humans; Mental Recall | 1998 |
Rate of caffeine metabolism and risk of spontaneous abortion.
Topics: Abortion, Spontaneous; Adult; Arylamine N-Acetyltransferase; Caffeine; Case-Control Studies; Cytochr | 1998 |
Heavy caffeine intake in pregnancy and sudden infant death syndrome. New Zealand Cot Death Study Group.
Topics: Caffeine; Carbonated Beverages; Case-Control Studies; Coffee; Female; Humans; Infant; Pregnancy; Pre | 1998 |
Differences in preconceptional and prenatal behaviors in women with intended and unintended pregnancies.
Topics: Adult; Alcohol Drinking; Caffeine; Diet; Female; Health Behavior; Humans; Mothers; Preconception Car | 1998 |
Caffeine intake and low birth weight: a population-based case-control study.
Topics: Beverages; Birth Weight; Caffeine; Case-Control Studies; Coffee; Female; Fetal Growth Retardation; G | 1998 |
Determination of nicotine, cotinine and caffeine in meconium using high-performance liquid chromatography.
Topics: Adult; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Cotinine; | 1998 |
Contribution of sarcoplasmic reticular calcium to smooth muscle contractile activation: gestational dependence in isolated rat uterus.
Topics: Animals; Caffeine; Calcium; Calcium-Transporting ATPases; Cytosol; Enzyme Inhibitors; Female; In Vit | 1998 |
Does moderate alcohol consumption affect fertility? Follow up study among couples planning first pregnancy.
Topics: Adult; Alcohol Drinking; Caffeine; Female; Follow-Up Studies; Humans; Infertility, Female; Male; Men | 1998 |
Maternal alcohol and caffeine consumption and spontaneous abortion.
Topics: Abortion, Spontaneous; Alcohol Drinking; Beverages; Caffeine; California; Epidemiologic Methods; Fem | 1998 |
Smoking habits among Danish pregnant women from 1989 to 1996 in relation to sociodemographic and lifestyle factors.
Topics: Caffeine; Demography; Denmark; Female; Humans; Life Style; Pregnancy; Prenatal Care; Smoking; Socioe | 1998 |
Effects of amiloride on gustatory quality descriptions and temporal patterns produced by NaCl.
Topics: Adolescent; Adult; Amiloride; Caffeine; Female; Humans; Male; Pregnancy; Sodium Chloride; Taste; Tim | 1998 |
The probable role of nitric oxide on the relaxations obtained by caffeine and aminophylline in rat uterus.
Topics: Aminophylline; Animals; Caffeine; Female; In Vitro Techniques; Muscle Relaxation; Myometrium; Nitric | 1998 |
Unilateral trigeminal and facial nerve palsies associated with epidural analgesia in labour.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Anti-Inflammatory Agents, No | 1998 |
Heavy caffeine consumption in pregnancy, smoking, and sudden infant death syndrome.
Topics: Caffeine; Female; Humans; Infant; Pregnancy; Prenatal Exposure Delayed Effects; Smoking; Sudden Infa | 1998 |
Exposure to environmental and mainstream tobacco smoke and risk of spontaneous abortion.
Topics: Abortion, Spontaneous; Adult; Alcohol Drinking; Caffeine; Female; Humans; Logistic Models; Pregnancy | 1999 |
Prenatal effects of caffeine and restraint stress in mice.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Congenital Abnormalities; Eating; Embryonic and Feta | 1999 |
Associations between maternal decaffeinated and caffeinated coffee consumption and fetal growth and gestational duration.
Topics: Adult; Birth Weight; Caffeine; California; Coffee; Diet Surveys; Embryonic and Fetal Development; Fe | 1999 |
Is caffeine treatment given to preterm babies a risk factor for SIDS?
Topics: Caffeine; Central Nervous System Stimulants; Female; Humans; Infant, Newborn; Infant, Premature; Pre | 1999 |
Treatment for postdural puncture headache associated with late postpartum eclampsia.
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Benzoat | 1999 |
Pregnant rat myometrial cells show heterogeneous ryanodine- and caffeine-sensitive calcium stores.
Topics: Animals; Caffeine; Calcium; DNA, Complementary; Female; Intracellular Membranes; Molecular Sequence | 1999 |
Caffeine and alcohol as risk factors for sudden infant death syndrome. Nordic Epidemiological SIDS Study.
Topics: Alcohol Drinking; Caffeine; Dose-Response Relationship, Drug; Female; Humans; Infant; Infant, Newbor | 1999 |
Anti-genotoxicity and glutathione S-transferase activity in mice pretreated with caffeinated and decaffeinated coffee.
Topics: Animals; Antimutagenic Agents; Caffeine; Central Nervous System Stimulants; Coffee; Female; Glutathi | 1999 |
Maternal serum paraxanthine, a caffeine metabolite, and the risk of spontaneous abortion.
Topics: Abortion, Spontaneous; Adult; Caffeine; Case-Control Studies; Female; Humans; Odds Ratio; Pregnancy; | 1999 |
Caffeine--filtering the facts.
Topics: Abortion, Spontaneous; Breast Feeding; Caffeine; Child Development; Female; Fetus; Humans; Infant; P | 1999 |
[Behavioral-teratological effects of caffeine on mice].
Topics: Animals; Caffeine; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Female; Matern | 1998 |
Effects of added caffeine on results following artificial insemination with fresh and refrigerated rabbit semen.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Female; Fertility; Insemination, Artificial; L | 2000 |
Caffeine consumption and the risk of spontaneous abortions.
Topics: Abortion, Spontaneous; Caffeine; Case-Control Studies; Female; Humans; Pregnancy; Reproducibility of | 2000 |
Caffeine during pregnancy? In moderation.
Topics: Abortion, Spontaneous; Animals; Caffeine; Case-Control Studies; Coffee; Cohort Studies; Female; Feta | 2000 |
Tobacco, alcohol, and caffeine use and cessation in early pregnancy.
Topics: Adult; Alcohol Drinking; Caffeine; Female; Health Behavior; Humans; Logistic Models; Minnesota; Mult | 2000 |
Sex-specific triggers for right ventricular outflow tract tachycardia.
Topics: Adult; Aged; Bundle-Branch Block; Caffeine; Central Nervous System Stimulants; Contraceptive Agents, | 2000 |
The effects of short-time caffeine administration on skeleton development in Wistar rats.
Topics: Animals; Bone and Bones; Bone Development; Caffeine; Central Nervous System Stimulants; Female; Preg | 2000 |
Caffeine induces in vivo premature appearance of telencephalic vesicles.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Embryonic an | 2000 |
Maternal caffeine consumption during pregnancy does not affect preimplantation development but delays early postimplantation growth in rat embryos.
Topics: Animals; Blastocyst; Caffeine; Embryonic and Fetal Development; Embryonic Development; Female; Fetal | 1999 |
Maternal caffeine and its effect on the fetus.
Topics: Abortion, Spontaneous; Animals; Aorta; Caffeine; Chick Embryo; Female; Humans; Microscopy, Electron; | 2000 |
Maternal caffeine intake has minor effects on adenosine receptor ontogeny in the rat brain.
Topics: Adenosine; Animals; Animals, Newborn; Autoradiography; Brain; Caffeine; Female; Gene Expression Regu | 2000 |
Caffeine during pregnancy? Correction.
Topics: Abortion, Spontaneous; Caffeine; Dose-Response Relationship, Drug; Female; Fetal Growth Retardation; | 2000 |
Cerebral artery sarcoplasmic reticulum Ca(2+) stores and contractility: changes with development.
Topics: Age Factors; Animals; Caffeine; Calcium; Calcium Channels, L-Type; Calcium-Transporting ATPases; Cer | 2000 |
Caffeine decreases the occurrence of cadmium-induced forelimb ectrodactyly in C57BL/6J mice.
Topics: Abnormalities, Drug-Induced; Animals; Cadmium; Caffeine; Central Nervous System Stimulants; Crosses, | 2000 |
Caffeine intake and the risk of first-trimester spontaneous abortion.
Topics: Abortion, Spontaneous; Adolescent; Adult; Caffeine; Case-Control Studies; Chromosome Aberrations; Ch | 2000 |
[Ca(2+)](i) signaling in renal arterial smooth muscle cells of pregnant rat is enhanced during inhibition of NOS.
Topics: Animals; Arginine; Caffeine; Calcium; Calcium Signaling; Enzyme Inhibitors; Female; Fluorescent Dyes | 2001 |
The associations of maternal caffeine consumption and nausea with spontaneous abortion.
Topics: Abortion, Spontaneous; Adult; Caffeine; Female; Humans; Minnesota; Nausea; Odds Ratio; Pregnancy; Pr | 2001 |
Embryotoxic effect of low doses of caffeine.
Topics: Animals; Caffeine; Ecchymosis; Embryonic and Fetal Development; Female; Fetal Diseases; Fetus; In Vi | 1999 |
[Should we advice pregnant women not to intake coffee and other products containing caffeine?].
Topics: Abortion, Spontaneous; Caffeine; Coffee; Female; Humans; Pregnancy; Risk Factors | 2001 |
Caffeine-induced telencephalic vesicle evagination in early post-implantation mouse embryos involves cAMP-dependent protein kinase (PKA) inhibition.
Topics: Animals; Base Sequence; Caffeine; Carrier Proteins; Cyclic AMP-Dependent Protein Kinases; Female; Ge | 2001 |
Interactions in developmental toxicology: combined action of restraint stress, caffeine, and aspirin in pregnant mice.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Caffeine; Embryonic and Fetal Development; Female; Ma | 2001 |
Caffeine-induced hypokalemic paralysis in pregnancy.
Topics: Adult; Caffeine; Carbonated Beverages; Female; Humans; Hypokalemia; Paralysis; Pregnancy; Pregnancy | 2001 |
Maternal caffeine intake and intrauterine growth retardation.
Topics: Adult; Birth Weight; Caffeine; Central Nervous System Stimulants; Cohort Studies; Female; Fetal Grow | 2001 |
A simple high-pressure liquid chromatography cotinine assay: validation of smoking status in pregnant women.
Topics: Biomarkers; Caffeine; Chromatography, High Pressure Liquid; Coffee; Cotinine; Creatinine; Female; Hu | 2001 |
The effect of pregnancy on cytochrome P4501A2, xanthine oxidase, and N-acetyltransferase activities in humans.
Topics: Adult; Analysis of Variance; Arylamine N-Acetyltransferase; Caffeine; Cytochrome P-450 CYP1A2; Femal | 2001 |
Caffeine does not affect excitotoxic brain lesions in newborn mice.
Topics: Animals; Animals, Newborn; Caffeine; Cerebral Ventricles; Female; Humans; Infant, Newborn; Infant, P | 2001 |
Another case of excessive caffeine and hypokalemia in pregnancy.
Topics: Caffeine; Female; Humans; Hypokalemia; Pregnancy; Pregnancy Complications | 2001 |
Caffeine metabolism and the risk of spontaneous abortion of normal karyotype fetuses.
Topics: Abortion, Spontaneous; Adult; Arylamine N-Acetyltransferase; Caffeine; Case-Control Studies; Central | 2001 |
Perinatal respiratory control and its modulation by adenosine and caffeine in the rat.
Topics: Adenosine; Animals; Animals, Newborn; Autoradiography; Brain Stem; Caffeine; Female; In Situ Hybridi | 2002 |
Distinct pharmacological mechanisms leading to c-fos gene expression in the fetal suprachiasmatic nucleus.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenosine; Animals; Caffeine; Central Ne | 2001 |
Bayesian modeling of the level and duration of fertility in the menstrual cycle.
Topics: Algorithms; Bayes Theorem; Biometry; Caffeine; Female; Fertility; Humans; Markov Chains; Menstrual C | 2001 |
Maternal serum caffeine metabolites and small-for-gestational age birth.
Topics: Adult; Analysis of Variance; Caffeine; Chi-Square Distribution; Female; Humans; Infant, Newborn; Inf | 2002 |
Effects of caffeine and its reactive metabolites theophylline and theobromine on the differentiating testis.
Topics: Animals; Caffeine; Cell Differentiation; Female; Gestational Age; Leydig Cells; Male; Maternal-Fetal | 2001 |
Effect of caffeine exposure during pregnancy on birth weight and gestational age.
Topics: Adult; Birth Weight; Caffeine; Central Nervous System Stimulants; Cohort Studies; Female; Fetal Grow | 2002 |
Heterogeneity in assessing self-reports of caffeine exposure: implications for studies of health effects.
Topics: Beverages; Cacao; Caffeine; Carbonated Beverages; Coffee; Female; Humans; Medical Records; Pregnancy | 2002 |
Combined effects of acetaminophen, isopropylantipyrine and caffeine on pregnant and nonpregnant liver.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrin | 2001 |
Effect of inhibiting the sarcoplasmic reticulum on spontaneous and oxytocin-induced contractions of human myometrium.
Topics: Adult; Caffeine; Calcium; Calcium Channels; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fem | 2002 |
[Treatment of post-dural-puncture headache with intravenous cortisone].
Topics: Acetaminophen; Adult; Analgesics; Anesthesia, Epidural; Anesthesia, Obstetrical; Anti-Inflammatory A | 2002 |
[Birthweight and caffeine consumption].
Topics: Adult; Birth Weight; Caffeine; Case-Control Studies; Female; Fetal Growth Retardation; Gestational A | 2002 |
Effects of prenatal exposure to combination of acetaminophen, isopropylantipyrine and caffeine on intrauterine development in rats.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, No | 2002 |
A prospective study of the effects of female and male caffeine consumption on the reproductive endpoints of IVF and gamete intra-Fallopian transfer.
Topics: Abortion, Spontaneous; Adult; Caffeine; Central Nervous System Stimulants; Coffee; Delivery, Obstetr | 2002 |
Accumulation of nicotine in the uterine fluid of the six-day pregnant rabbit.
Topics: Animals; Blastocyst; Blood Proteins; Body Fluids; Caffeine; Cotinine; DDT; Embryonic Development; Es | 1976 |
Fetal breathing: a review.
Topics: Amniocentesis; Animals; Barbiturates; Benzodiazepines; Betamethasone; Blood Glucose; Blood Pressure; | 1979 |
Human placental cAMP phosphodiesterase activity kinetic properties and sensitivity to some drugs and hormones.
Topics: Caffeine; Cyclic AMP; Epinephrine; Estradiol; Female; Flufenamic Acid; Hormones; Humans; Imidazoles; | 1975 |
The effect of pregnancy on the control of lipolysis in fat cells isolated from human adipose tissue.
Topics: Adipose Tissue; Adult; Bucladesine; Caffeine; Cyclic AMP; Epinephrine; Female; Glycerol; Humans; Lip | 1975 |
Cyclic AMP phosphodiesterase activity in fetal and adult muscle of the rhesus monkey.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffei | 1976 |
Effect of Indomethacin on cyclic AMP phosphodiesterase activity in myometrium from pregnant rhesus monkeys.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Caffeine; Drug Synergism; Epinephrine; Female; Haplorh | 1976 |
[3'5'-Cyclic AMP phosphodiesterase activity in the internal and external layers of human myometrium at the end of pregnancy].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Caffeine; Female; Humans; Imidazoles; Indomethacin; Kinetics; M | 1977 |
[Human chorionic thyrotropin and cyclic AMP in the thyroid gland (author's transl)].
Topics: Adsorption; Animals; Caffeine; Chorionic Gonadotropin; Cyclic AMP; Female; Guinea Pigs; Humans; In V | 1977 |
The hormonal regulation of fetal lung maturation.
Topics: Adrenal Cortex Hormones; Aminophylline; Animals; Caffeine; Cyclic AMP; Estrogens; Female; Fetus; Hor | 1979 |
Nutrition during pregnancy, lactation, and oral contraception.
Topics: Body Weight; Caffeine; Contraceptives, Oral; Dietary Proteins; Ethanol; Feeding Behavior; Female; Fo | 1979 |
Measurement of mutagenesis in mammalian cells.
Topics: Amniotic Fluid; Animals; Caffeine; Cell Line; Cell Survival; Chromosomes; Cricetinae; Dose-Response | 1979 |
Testing for behavioral effects of agents.
Topics: Animals; Atropine; Behavior, Animal; Brain; Caffeine; Conditioning, Operant; Female; Mice; Motor Act | 1979 |
Similarity of the mechanism of chemical carcinogen-initiated teratogenesis and carcinogenesis in mice.
Topics: 4-Nitroquinoline-1-oxide; Abnormalities, Drug-Induced; Animals; Caffeine; Carcinogens; Congenital Ab | 1977 |
Alcohol, caffeine, and nicotine as factors in pregnancy.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Alcohol Drinking; Animals; Birth Weight; Caffe | 1979 |
The effect of 5-bromodeoxyuridine on mouse limb development: a scanning electron microscope study.
Topics: Abnormalities, Drug-Induced; Animals; Bromodeoxyuridine; Caffeine; Extremities; Female; Limb Deformi | 1977 |
Glucagon, insulin and glucose homeostasis in the fetal lamb.
Topics: Amino Acids; Animals; Caffeine; Epinephrine; Female; Fetus; Glucagon; Glucose; Insulin; Liver Glycog | 1977 |
Effect of maternal glucose ingestion on fetal breathing and body movements in late pregnancy.
Topics: Blood Glucose; Caffeine; Female; Fetus; Glucose; Humans; Movement; Pregnancy; Pregnancy Trimester, T | 1978 |
More on caffeine and pregnancy.
Topics: Caffeine; Canada; Female; Humans; Indians, North American; Infant; Infant Mortality; Infant, Newborn | 1978 |
Further developed device for human sperm freezing by the twenty-minute method.
Topics: Caffeine; Female; Humans; Insemination, Artificial; Male; Pregnancy; Semen Preservation; Sperm Motil | 1978 |
Insemination of husband's semen with and without the addition of caffeine.
Topics: Caffeine; Female; Humans; Insemination, Artificial; Insemination, Artificial, Homologous; Male; Preg | 1978 |
In vitro fertilizing ability of testicular, epididymal, and ejaculated rabbit spermatozoa.
Topics: Animals; Caffeine; Ejaculation; Epididymis; Female; Fertilization; Male; Ovum; Pregnancy; Rabbits; S | 1978 |
Evaluation of the teratogenic potential of fresh-brewed coffee and caffeine in the rat.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Body Weight; Caffeine; Coffee; Cricetinae; Female; Le | 1978 |
More effects of caffeine.
Topics: Animals; Caffeine; Dose-Response Relationship, Drug; Female; Humans; Pregnancy; Pregnancy Complicati | 1978 |
Alteration of ovine fetal respiratory-like activity by diazepam, caffeine, and doxapram.
Topics: Animals; Blood Gas Analysis; Caffeine; Depression, Chemical; Diazepam; Doxapram; Female; Fetal Blood | 1977 |
[Failure of oral contraception--probably because of interaction with phenemal].
Topics: Adult; Appetite Depressants; Ascorbic Acid; Caffeine; Drug Interactions; Ephedrine; Estrenes; Ethiny | 1977 |
Caffeine and pregnancy. A retrospective survey.
Topics: Abortion, Spontaneous; Adult; Caffeine; Coffee; Female; Fetal Death; Humans; Male; Pregnancy; Pregna | 1977 |
[Caffeine-stimulated lipolysis in relation to pathologic pregnancy].
Topics: Adult; Caffeine; Fatty Acids, Nonesterified; Female; Glycerol; Humans; Labor, Obstetric; Pregnancy | 1976 |
Mitigation of caffeine-induced fetopathy in mice by pretreatment with beta-adrenergic blocking agents.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Female; Fetus; Mice; Mice, Inbred ICR; Pregnancy; Pr | 1976 |
Accumulation of caffeine and its metabolites in rat fetal brain and liver.
Topics: Animals; Brain; Caffeine; Carbon Radioisotopes; Female; Fetus; Gestational Age; Injections, Intramus | 1975 |
Clinical applications of gas chromatograph/mass spectrometer/computer systems.
Topics: Autoanalysis; Caffeine; Chromatography, Gas; Computers; Diazepam; Evaluation Studies as Topic; Femal | 1975 |
Mitigation of caffeine-induced teratogenicity in mice by prior chronic caffeine ingestion.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Female; Fetal Death; Gestational Age; Mice; Mice, In | 1975 |
Caffeine-mediated changes of sex ratio in Chinese hamsters, Cricetulus griseus.
Topics: Administration, Oral; Animals; Caffeine; Cricetinae; Female; Humans; Male; Pregnancy; Sex Determinat | 1975 |
Identification and quantification of drugs in human amniotic fluid.
Topics: Amniotic Fluid; Caffeine; Chromatography, Gas; Computers; Female; Fetal Blood; Humans; Mass Spectrom | 1975 |
Prevention of caffeine-induced cleft palate by L-glutamic acid.
Topics: Animals; Body Weight; Caffeine; Cleft Palate; Diet; Feeding Behavior; Female; Fetus; Glutamates; Mic | 1976 |
Caffeine-mediated effects on reproductive health over two generations in rats.
Topics: Animals; Birth Weight; Caffeine; Cohort Effect; Dose-Response Relationship, Drug; Female; Labor, Obs | 1992 |
Changes in secondary structure of DNA of rat embryos following treatment with diethylnitrosamine and methylazoxymethanol acetate in vivo.
Topics: Analysis of Variance; Animals; Caffeine; Chromatography, DEAE-Cellulose; Diethylnitrosamine; DNA; DN | 1992 |
Fish consumption and reproductive outcomes in Green Bay, Wisconsin.
Topics: Adolescent; Adult; Alcohol Drinking; Animals; Birth Weight; Caffeine; Female; Fish Products; Fishes; | 1992 |
[Effects of coffee on the respiratory system].
Topics: Adult; Apnea; Bronchial Neoplasms; Caffeine; Coffee; Female; Humans; Infant, Newborn; Infant, Newbor | 1992 |
Relationship of prenatal caffeine exposure and zinc supplementation on fetal rat brain growth.
Topics: Administration, Oral; Alkaline Phosphatase; Animals; Body Weight; Brain Chemistry; Caffeine; Diet; F | 1992 |
Effects of caffeine on the DNA and protein synthesis of the protein-energy malnourished neonatal cardiac muscle cells in culture.
Topics: Animals; Animals, Newborn; Caffeine; Cells, Cultured; DNA; Female; Heart; Leucine; Muscle Proteins; | 1992 |
Acetylcholine enhances NMDA-evoked calcium rise in hippocampal neurons.
Topics: Acetylcholine; Animals; Atropine; Caffeine; Calcium; Cells, Cultured; Female; Hippocampus; N-Methyla | 1992 |
The effects of caffeine on the maxillary composition in the newborn rat.
Topics: Animals; Animals, Newborn; Animals, Suckling; Bone Density; Caffeine; Female; Male; Maternal-Fetal E | 1992 |
Smoking and caffeine and alcohol intake during pregnancy in a northern population: effect on fetal growth.
Topics: Adolescent; Adult; Alcohol Drinking; Analysis of Variance; Birth Weight; Body Height; Caffeine; Ceph | 1992 |
Gestational exposure to diazepam increases sensitivity to convulsants that act at the GABA/benzodiazepine receptor complex.
Topics: Animals; Bicuculline; Caffeine; Carbolines; Cerebral Cortex; Chlorides; Convulsants; Diazepam; Femal | 1991 |
Caffeine administered during pregnancy augments subsequent lactation in mice.
Topics: Animals; Birth Weight; Caffeine; Cell Count; DNA; Female; Lactation; Litter Size; Mammary Glands, An | 1991 |
Exploring the role of an endogenous caffeine-like substance in the pathogenesis of schizophrenia.
Topics: Brain; Caffeine; Female; gamma-Aminobutyric Acid; Humans; Pregnancy; Pregnancy Complications; Recept | 1991 |
Caffeine and spontaneous abortion of known karyotype.
Topics: Abortion, Spontaneous; Adult; Caffeine; Case-Control Studies; Chromosome Aberrations; Female; Humans | 1991 |
Somatic development of the infant monkey following in utero exposure to caffeine.
Topics: Animals; Body Weight; Caffeine; Female; Half-Life; Humans; Infant, Newborn; Macaca fascicularis; Mal | 1991 |
Lasting effects of early chronic caffeine feeding on rats' behavior and brain in later life.
Topics: Animals; Behavior, Animal; Body Weight; Brain; Caffeine; DNA Replication; Female; Motor Activity; Or | 1991 |
Dissociation between the effects of theophylline and caffeine on premature airway smooth muscles.
Topics: Acetylcholine; Animals; Animals, Newborn; Caffeine; Disease Models, Animal; Female; Humans; Infant, | 1991 |
Potentiation by caffeine of the frequencies of micronuclei induced by mitomycin C and cyclophosphamide in young mice.
Topics: Alkylating Agents; Animals; Caffeine; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Syner | 1991 |
Miscarriage, caffeine, and the epiphenomena of pregnancy: the causal model.
Topics: Abortion, Spontaneous; Caffeine; Female; Humans; Nausea; Pregnancy; Pregnancy Complications | 1991 |
Interaction between caffeine and zinc on brain in newborn rats.
Topics: Alkaline Phosphatase; Animals; Animals, Newborn; Brain; Caffeine; Drug Interactions; Female; Lactati | 1991 |
Assessment of reporting consistency in a case-control study of spontaneous abortions.
Topics: Abortion, Spontaneous; Adult; Caffeine; California; Case-Control Studies; Drinking; Educational Stat | 1991 |
Caffeine consumption during pregnancy and fetal growth.
Topics: Adult; Birth Weight; Caffeine; Case-Control Studies; Female; Fetal Growth Retardation; Humans; Infan | 1991 |
Cigarette smoking, tea and coffee drinking, and subfecundity.
Topics: Adult; Caffeine; Coffee; Denmark; Epidemiologic Methods; Female; Fertility; Humans; Male; Pregnancy; | 1991 |
Pregnancy-induced changes in drug metabolism in epileptic women.
Topics: Adult; Anticonvulsants; Biological Availability; Blood Proteins; Caffeine; Chromatography, High Pres | 1991 |
Miscarriage, caffeine, and the epiphenomena of pregnancy: the causal model.
Topics: Abortion, Spontaneous; Beverages; Caffeine; Female; Humans; Nausea; Pregnancy; Pregnancy Complicatio | 1991 |
Caffeine consumption during pregnancy and spontaneous abortion.
Topics: Abortion, Spontaneous; Adult; Beverages; Caffeine; California; Case-Control Studies; Demography; Fem | 1991 |
Effects of chronic caffeine consumption in pregnant monkeys (Macaca fascicularis) on blood and urine clinical chemistry parameters.
Topics: Animals; Blood Glucose; Caffeine; Cholesterol; Creatinine; Estrogens; Female; Macaca fascicularis; P | 1991 |
Interactive effects of ethanol and caffeine on rat fetal hepatocyte replication and EGF receptor expression.
Topics: Animals; Caffeine; Cell Differentiation; Cell Division; Cells, Cultured; DNA Replication; Dose-Respo | 1991 |
Cytochrome P450 IA2 activity in man measured by caffeine metabolism: effect of smoking, broccoli and exercise.
Topics: Arylamine N-Acetyltransferase; Caffeine; Contraceptives, Oral; Cytochrome P-450 CYP1A2; Cytochrome P | 1991 |
Effects on birthweight of alcohol and caffeine consumption in smoking women.
Topics: Alcohol Drinking; Birth Weight; Caffeine; Embryonic and Fetal Development; Ethanol; Female; Humans; | 1991 |
Risk factors for early pregnancy loss.
Topics: Abortion, Spontaneous; Adult; Caffeine; Diethylstilbestrol; Female; Humans; Maternal Age; North Caro | 1990 |
Fetal and newborn lambs differ in their cardiopulmonary responsiveness to adenosine agonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Animals, Newborn; Blood Pressure; Bradycardia | 1990 |
Maternal-fetal electrocardiographic effects and pharmacokinetics after an acute i.v. administration of caffeine to the pregnant rat.
Topics: Animals; Caffeine; Electrocardiography; Female; Fetus; Maternal-Fetal Exchange; Pregnancy; Pregnancy | 1990 |
Interaction between caffeine intake and heart zinc concentrations in the rat.
Topics: Animals; Caffeine; Calcium; Calcium-Transporting ATPases; Female; Fetal Heart; Heart; Magnesium; Mal | 1990 |
The effect of methylxanthines on milk volume and composition, and growth of rat pups.
Topics: Animals; Animals, Newborn; Body Weight; Caffeine; Fatty Acids; Female; Lactation; Milk; Pregnancy; R | 1990 |
Effect of methylxanthines on lactational performance of rats.
Topics: Animals; Animals, Newborn; Body Weight; Caffeine; Drinking; Eating; Female; Lactation; Pregnancy; Ra | 1990 |
Sex-and age-dependent effects of prenatal exposure to caffeine on open-field behavior, emergence latency and adrenal weights in rats.
Topics: Adrenal Glands; Aging; Animals; Behavior, Animal; Caffeine; Exploratory Behavior; Female; Male; Moto | 1990 |
Influence of caffeine administered during pregnancy on the early differentiation of fetal rat ovaries and testes.
Topics: 3-Hydroxysteroid Dehydrogenases; Administration, Oral; Animals; Caffeine; Cell Differentiation; Fema | 1990 |
Caffeine: how much is too much?
Topics: Abnormalities, Drug-Induced; Adult; Caffeine; Cardiovascular System; Female; Humans; Infant, Newborn | 1990 |
Craniofacial and limb development in early rat embryos following in utero exposure to ethanol and caffeine.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Ethanol; Extremities; Facial Bones; Female; Limb Def | 1990 |
Maternal caffeine ingestion increases the tyrosine level in neonatal rat cerebrum.
Topics: Amino Acids; Animals; Animals, Newborn; Animals, Suckling; Brain; Caffeine; Female; Liver; Maternal- | 1990 |
Various levels of maternal caffeine ingestion during gestation affects biochemical parameters of fetal rat brain differently.
Topics: Animals; Brain; Brain Chemistry; Caffeine; Dose-Response Relationship, Drug; Female; Fetus; Maternal | 1990 |
Coffee consumption as trigger for insulin dependent diabetes mellitus in childhood.
Topics: Caffeine; Coffee; Diabetes Mellitus, Type 1; Female; Finland; Humans; Maternal-Fetal Exchange; Pregn | 1990 |
Caffeine acting on pregnant rat myometrium: analysis of its relaxant action and its failure to release Ca2+ from intracellular stores.
Topics: Animals; Caffeine; Calcium; Female; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth; Myometri | 1990 |
Prenatal effects of maternal caffeine intake and dietary high protein on mandibular development in fetal rats.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Caffeine; Dietary Proteins; Female; Fetal Blood; Ma | 1990 |
Effects of caffeine intake during gestation and lactation on bones of young growing rats.
Topics: Animals; Bone Development; Caffeine; Female; Femur; Hardness; Lactation; Male; Mandible; Organ Size; | 1990 |
Sixth International Caffeine Workshop, Hong Kong, 7-10 August 1989.
Topics: Adenosine; Animals; Arrhythmias, Cardiac; Bone Development; Caffeine; DNA Replication; Female; Human | 1990 |
Effects of maternal caffeine with zinc intake during gestation and lactation on bone development in newborn rats.
Topics: Animals; Bone Development; Caffeine; Diet; Embryonic and Fetal Development; Female; Femur; Lactation | 1990 |
Effects of combinations of maternal agents on the fetal cerebrum in rat--ethanol or caffeine with X-irradiation in utero.
Topics: Animals; Body Weight; Brain; Caffeine; DNA; Ethanol; Female; Fetus; Lipid Peroxides; Organ Size; Pre | 1985 |
Chronic caffeine intake by rat dams during gestation and lactation affects various parts of the neonatal brain.
Topics: Animals; Brain; Brain Chemistry; Caffeine; Cholesterol; DNA; Embryonic and Fetal Development; Female | 1986 |
Inhibitory effect of caffeine on 5-azacytidine-induced digital malformations in the rat.
Topics: Abnormalities, Drug-Induced; Animals; Azacitidine; Caffeine; Dose-Response Relationship, Drug; Femal | 1987 |
Caffeine and reduction of fetal ossification in the rat: fact or artifact?
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Dose-Response Relationship, Drug; Female; Gestationa | 1988 |
Chronic caffeine intake alters the composition of various parts of the brain in young growing rats.
Topics: Animals; Animals, Newborn; Brain Chemistry; Caffeine; Cholesterol; DNA; Female; Lactation; Pregnancy | 1988 |
Effects of caffeine and 3-isobutyl 1-methyl xanthine on caprine milk secretion.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Caffeine; Fats; Female; Goats; Infusions, Intravenous; Injecti | 1988 |
Fetal arrhythmia caused by excessive intake of caffeine by pregnant women.
Topics: Adult; Arrhythmias, Cardiac; Caffeine; Female; Fetal Blood; Fetal Diseases; Humans; Infant, Newborn; | 1989 |
Effects on birth weight of smoking, alcohol, caffeine, socioeconomic factors, and psychosocial stress.
Topics: Adolescent; Adult; Alcohol Drinking; Birth Weight; Caffeine; Coffee; Female; Gestational Age; Humans | 1989 |
Caffeine-induced inhibition of calcium channel current in cultured smooth cells from pregnant rat myometrium.
Topics: Animals; Binding, Competitive; Caffeine; Calcium Channels; Electrophysiology; Female; In Vitro Techn | 1989 |
Caffeinated beverages and decreased fertility.
Topics: Beverages; Caffeine; Female; Humans; Infertility, Female; Pregnancy; Pregnancy Trimester, First | 1989 |
Effects of orally administered caffeine on cellular response in protein energy-malnourished neonatal rat brain.
Topics: Administration, Oral; Animals; Animals, Newborn; Body Weight; Brain; Caffeine; Cholesterol; DNA; Fem | 1985 |
Neural tube defects in early rat embryos following maternal treatment with ethanol and caffeine.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Central Nervous System; Ethanol; Female; Neural Tube | 1989 |
Influence of nicotine and caffeine on skeletal development in the rat.
Topics: Animals; Bone Development; Caffeine; Female; Infusion Pumps; Nicotine; Osteogenesis; Pregnancy; Rats | 1989 |
Caffeinated beverages and low birthweight: a case-control study.
Topics: Adult; Caffeine; Embryonic and Fetal Development; Epidemiologic Methods; Female; Humans; Infant, Low | 1989 |
Alteration of the effects of caffeine by prenatal stress.
Topics: Animals; Body Temperature; Caffeine; Corticosterone; Defecation; Female; Male; Motor Activity; Pregn | 1989 |
[Caffeine and pregnancy].
Topics: Animals; Caffeine; Female; Humans; Pregnancy | 1989 |
Transplacentally acquired caffeine and the occurrence of apnea, bradycardia, and periodic breathing in preterm infants: preliminary communication.
Topics: Apnea; Bradycardia; Caffeine; Cheyne-Stokes Respiration; Chromatography, High Pressure Liquid; Femal | 1989 |
The effects of maternal caffeine intake during pregnancy on mineral contents of fetal rat bone.
Topics: Animals; Caffeine; Embryonic and Fetal Development; Female; Mandible; Minerals; Pregnancy; Random Al | 1989 |
Agreement between laboratory tests and self-reports of alcohol, tobacco, caffeine, marijuana and other drug use in post-partum women.
Topics: Adult; Alanine Transaminase; Alcohol Drinking; Aspartate Aminotransferases; Blood Cell Count; Caffei | 1986 |
Induction of sister chromatid exchange in preimplantation mouse embryos in vitro by 3H-thymidine or ultraviolet light in combination with caffeine.
Topics: Animals; Caffeine; Embryonic Development; Female; In Vitro Techniques; Mice; Mutagenicity Tests; Pre | 1986 |
Potentiating effect of caffeine on embryotoxicity of cyclophosphamide treatment in vivo during the preimplantation period.
Topics: Animals; Caffeine; Cell Differentiation; Chromosome Aberrations; Cyclophosphamide; Depression, Chemi | 1987 |
Caffeine cubes.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Female; Humans; Mice; Pregnancy | 1988 |
Postpartum seizure after epidural blood patch and intravenous caffeine sodium benzoate.
Topics: Adult; Analgesia, Epidural; Anesthesia, Obstetrical; Benzoates; Blood; Caffeine; Drug Combinations; | 1989 |
Combined effects of radiation and caffeine on embryonic development in mice.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Body Weight; Caffeine; Embry | 1989 |
[Antagonistic effects of ascorbic acid on caffeine-induced embryotoxic and teratogenic activities in rats].
Topics: Abnormalities, Drug-Induced; Animals; Ascorbic Acid; Caffeine; Female; Pregnancy; Rats; Rats, Inbred | 1986 |
Influence of nicotine and caffeine on rat embryonic development.
Topics: Animals; Caffeine; Embryonic and Fetal Development; Female; Nicotine; Pregnancy; Rats; Rats, Inbred | 1988 |
Behavioural similarities between mother rats and benzodiazepine-treated non-maternal animals.
Topics: Aggression; Animals; Benzodiazepines; Caffeine; Carbolines; Fear; Feeding Behavior; Female; Humans; | 1985 |
Caffeine: is it hazardous to your patients' health?
Topics: Cacao; Caffeine; Cardiovascular System; Central Nervous System; Female; Food Analysis; Gastric Acid; | 1986 |
Protein-energy malnutrition in rats during pregnancy modifies the effects of caffeine on fetal bones.
Topics: Animals; Body Weight; Bone and Bones; Caffeine; Female; Fetus; Gestational Age; Pregnancy; Pregnancy | 1986 |
Teratogenicity of di(2-ethylhexyl) phthalate, 2-ethylhexanol, 2-ethylhexanoic acid, and valproic acid, and potentiation by caffeine.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Caproates; Diethylhexyl Phthalate; Drug Synergism; F | 1987 |
Contributions of maternal alcohol, caffeine, and cigarette use to neonatal status.
Topics: Abnormalities, Drug-Induced; Caffeine; Ethanol; Female; Humans; Infant, Newborn; Pregnancy; Smoking | 1987 |
Caffeine induces cardiac and other malformations in the rat.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Caffeine; Female; Heart Defects, Congenital; L | 1987 |
Caffeine does not contract skinned uterine fibers with a functional Ca store.
Topics: Animals; Caffeine; Calcimycin; Calcium; Egtazic Acid; Female; In Vitro Techniques; Inosine Triphosph | 1988 |
Properties of intracellular calcium stores in pregnant rat myometrium.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Caffeine; Calcimycin; Calcium; Female; Guanosine Triph | 1988 |
Caffeine, an exquisitely specific inhibitor of osteogenic differentiation.
Topics: Animals; Caffeine; Cell Differentiation; Female; Fetus; Growth Inhibitors; Mice; Ossification, Heter | 1988 |
Effects of different levels of caffeine supplemented to the maternal diet on the brains of newborn rats and their dams.
Topics: Alkaline Phosphatase; Animals; Animals, Newborn; Body Weight; Brain; Caffeine; Cholesterol; Chromato | 1988 |
Male mediated caffeine effects over two generations of rats.
Topics: Animals; Caffeine; Corticosterone; Female; Fetal Death; Litter Size; Male; Pregnancy; Rats; Rats, In | 1988 |
[Pharmacokinetics of caffeine and dimethylxanthines in plasma and saliva].
Topics: Adult; Caffeine; Female; Humans; Male; Middle Aged; Models, Biological; Pregnancy; Saliva; Theophyll | 1988 |
Prenatal microwave exposure and behavior.
Topics: Animals; Behavior, Animal; Body Temperature Regulation; Caffeine; Female; Fetus; Microwaves; Pregnan | 1988 |
Caffeine and health risk.
Topics: Caffeine; Cardiovascular System; Coffee; Female; Fetus; Humans; Male; Pregnancy; Risk Factors | 1988 |
Developmental hemodynamic changes in rat embryos at 11 to 15 days of gestation: normal data of blood pressure and the effect of caffeine compared to data from chick embryo.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Caffeine; Chick Embryo; Female; Heart Rate; Hemodynami | 1988 |
Caffeine disposition in the pregnant rabbit. I. Pharmacokinetics following administration by intravenous bolus and continuous zero-order infusion.
Topics: Animals; Caffeine; Female; Infusion Pumps; Infusions, Intravenous; Kinetics; Male; Pregnancy; Pregna | 1988 |
Caffeine disposition in the pregnant rabbit. II. Fetal distribution of caffeine and paraxanthine during chronic maternal caffeine administration.
Topics: Albumins; Amniotic Fluid; Animals; Caffeine; Female; Fetal Proteins; Fetus; Infusions, Intravenous; | 1988 |
Adverse pregnancy outcome in the monkey (Macaca fascicularis) after chronic caffeine exposure.
Topics: Abortion, Veterinary; Animals; Birth Weight; Body Weight; Caffeine; Female; Fetal Death; Macaca fasc | 1988 |
Birth defects following maternal exposure to ergotamine, beta blockers, and caffeine.
Topics: Abnormalities, Drug-Induced; Caffeine; Ergotamine; Female; Humans; Infant, Newborn; Migraine Disorde | 1988 |
Prenatal caffeine causes long lasting behavioral and neurochemical changes.
Topics: Animals; Avoidance Learning; Behavior, Animal; Brain; Caffeine; Cerebral Cortex; Choline; Discrimina | 1988 |
Interactions between caffeine and adenosine agonists in producing embryo resorptions and malformations in mice.
Topics: 2-Chloroadenosine; Abnormalities, Drug-Induced; Adenosine; Animals; Body Weight; Caffeine; Drug Admi | 1987 |
The mechanical response of the isolated longitudinal muscle of pregnant rat myometrium to adenosine triphosphate in the Ca-free solution containing various polyvalent cations.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Caffeine; Electric Stimulation; Female; In Vitro | 1987 |
Effects of caffeine administered during pregnancy on fetal development and subsequent function in the adult rat: prolonged effects on a second generation.
Topics: 3-Hydroxysteroid Dehydrogenases; Abnormalities, Drug-Induced; Animals; Birth Weight; Caffeine; Embry | 1987 |
Effects of administering caffeine to pregnant rats either as a single daily dose or as divided doses four times a day.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Caffeine; Dose-Response Relationship, Drug; Femal | 1987 |
Teratogenic effects in mice exposed to single dose of X-rays and prolonged administration of caffeine during pregnancy.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Caffeine; Female; Maternal-F | 1986 |
Alteration of effective exposure of dam and embryo to caffeine and its metabolites by treatment of mice with beta-naphthoflavone.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Caffeine; Drug Interactions; Embryo, | 1987 |
Effect of chronic caffeine intake on myocardial function during early growth.
Topics: Adipose Tissue; Animals; Caffeine; Coronary Circulation; Female; Heart; Hemodynamics; Lactation; Org | 1987 |
Caffeine and the benign encephalopathy of pregnancy.
Topics: Brain Diseases; Caffeine; Female; Humans; Pregnancy; Pregnancy Complications; Substance Withdrawal S | 1987 |
Effects of maternal caffeine ingestion on the perinatal cerebrum.
Topics: Animals; Body Weight; Brain; Caffeine; Female; Fetus; Maternal-Fetal Exchange; Organ Size; Placenta; | 1987 |
[Caffeine and pregnancy].
Topics: Caffeine; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange | 1987 |
The effects of long- and short-term maternal caffeine ingestion on human fetal breathing and body movements in term gestations.
Topics: Caffeine; Female; Fetal Movement; Fetus; Humans; Maternal-Fetal Exchange; Pregnancy; Respiration; Ti | 1987 |
Effect of protein malnutrition and maternal caffeine intake on the growth of fetal rat brain.
Topics: Animals; Brain; Brain Chemistry; Caffeine; Dietary Proteins; DNA Replication; Female; Maternal-Fetal | 1987 |
Potential reversibility of skeletal effects in rats exposed in utero to caffeine.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Body Weight; Bone and Bones; Caffeine; Drink | 1987 |
The association between low birth weight and caffeine consumption during pregnancy.
Topics: Adult; Birth Weight; Caffeine; Female; Fetal Growth Retardation; Gestational Age; Humans; Infant, Lo | 1987 |
[The effect of intrahepatic cholestasis in pregnancy on various forms of cytochrome P-450-dependent biotransformation reactions].
Topics: Biotransformation; Caffeine; Cholestasis, Intrahepatic; Cytochrome P-450 Enzyme System; Female; Huma | 1987 |
[Effect of caffeine on the contractility of the fetal heart muscle].
Topics: Caffeine; Dose-Response Relationship, Drug; Female; Fetal Heart; Gestational Age; Humans; Myocardial | 1987 |
Studies on the embryotoxic risk of exposure to caffeine and ethanol during the preimplantation period in the mouse.
Topics: Animals; Blastocyst; Caffeine; Ethanol; Female; Mice; Pregnancy; Risk Factors | 1987 |
Caffeine-cigarette interaction on fetal growth.
Topics: Birth Weight; Caffeine; Embryonic and Fetal Development; Female; Gestational Age; Humans; Infant, Ne | 1987 |
Effects of maternal smoking and caffeine habits on infantile apnea: a retrospective study.
Topics: Apnea; Birth Weight; Caffeine; Female; Humans; Infant, Newborn; Maternal Age; Pregnancy; Prenatal Ex | 1986 |
Reproduction study of caffeine administration to male Osborne-Mendel rats.
Topics: Administration, Oral; Animals; Body Weight; Caffeine; Copulation; Female; Fetal Death; Male; Pregnan | 1986 |
Prevention of caffeine-induced limb malformations by maternal adrenalectomy.
Topics: Adrenal Glands; Adrenalectomy; Animals; Caffeine; Catecholamines; Congenital Abnormalities; Female; | 1986 |
Alcohol use in primiparous women older than 30 years of age: relation to infant development.
Topics: Adult; Alcohol Drinking; Caffeine; Child Development; Educational Status; Female; Humans; Infant; In | 1986 |
Effect of chronic exposure to methylxanthines on diazepam cerebral binding in female rats and their offsprings.
Topics: Animals; Brain; Caffeine; Diazepam; Female; Lactation; Pregnancy; Pregnancy, Animal; Rats; Rats, Inb | 1986 |
Urinary metabolites of caffeine in pregnant women.
Topics: Caffeine; Female; Humans; Pregnancy; Theophylline; Uric Acid; Xanthines | 1986 |
Caffeine consumption during pregnancy and association with late spontaneous abortion.
Topics: Abortion, Incomplete; Caffeine; Female; Humans; Pregnancy; Risk; Time Factors | 1986 |
Fetal health locus of control scale: development and validation.
Topics: Adolescent; Adult; Caffeine; Female; Fetus; Health; Humans; Internal-External Control; Natural Child | 1986 |
Elimination of chronically consumed caffeine in the pregnant monkey (Macaca fascicularis).
Topics: Animals; Caffeine; Chromatography, High Pressure Liquid; Drinking; Eating; Female; Macaca fascicular | 1986 |
[Effect of caffeine on the fetal heart].
Topics: Caffeine; Female; Fetal Heart; Humans; Maternal-Fetal Exchange; Pregnancy | 1986 |
Teratogenicity of paraxanthine (1,7-dimethylxanthine) in C57BL/6J mice.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Cleft Palate; Dose-Response Relationship, Drug; Fema | 1986 |
[Profile of the consumption of caffeine, cigarettes and alcohol by women in Quebec during pregnancy].
Topics: Adult; Alcohol Drinking; Caffeine; Female; Humans; Pregnancy; Quebec; Smoking | 1986 |
Environmental factors affecting fetal growth.
Topics: Animals; Birth Weight; Body Weight; Caffeine; Coffee; Embryonic and Fetal Development; Ethanol; Fema | 1985 |
Variability of caffeine metabolism in humans.
Topics: Acetylation; Biotransformation; Caffeine; Dealkylation; Female; Half-Life; Humans; Kinetics; Liver D | 1985 |
[Coffee, tea and cola drinks: are they harmful?].
Topics: Adult; Caffeine; Carbonated Beverages; Child; Coca; Coffee; Female; Humans; Plants, Medicinal; Pregn | 1985 |
[Detection of caffeine, theophylline and theobromine in the umbilical cord blood and breast milk].
Topics: Caffeine; Female; Fetal Blood; Humans; Infant, Premature; Kinetics; Maternal-Fetal Exchange; Milk, H | 1985 |
Substance use in pregnancy among two groups of urban women in Papua New Guinea.
Topics: Adolescent; Adult; Alcohol Drinking; Areca; Attitude to Health; Beverages; Caffeine; Female; Humans; | 1985 |
Prenatal protein-calorie malnutrition and brain development.
Topics: Animals; Brain; Caffeine; Female; Fetal Growth Retardation; Growth Disorders; Humans; Infant, Newbor | 1985 |
Intrauterine death from ergotamine overdosage.
Topics: Adolescent; Caffeine; Cyclizine; Drug Combinations; Ergotamine; Ergotamines; Female; Fetal Death; Hu | 1985 |
Effects of orally-administered caffeine on the growth of tooth germs in protein-energy malnourished newborn rats.
Topics: Administration, Oral; Animals; Caffeine; Collagen; Dietary Proteins; Female; Hydroxyproline; Incisor | 1985 |
Applicability of the simple independent action model to epidemiologic studies involving two factors and a dichotomous outcome.
Topics: Abortion, Spontaneous; Acquired Immunodeficiency Syndrome; Biometry; Caffeine; Epidemiologic Methods | 1986 |
Caffeine consumption during pregnancy and association with late spontaneous abortion.
Topics: Abortion, Spontaneous; Adult; Beverages; Caffeine; Demography; Female; Food; Gestational Age; Humans | 1986 |
Behavioral effects of prenatal exposure to caffeine in rats.
Topics: Aging; Animals; Behavior, Animal; Caffeine; Emotions; Female; Male; Motor Activity; Pregnancy; Prena | 1986 |
[Ergotism with cerebral complications. Case report and review of the literature].
Topics: Adult; Brain; Brain Diseases; Caffeine; Drug Combinations; Ergotamine; Ergotism; Female; Humans; Mig | 1986 |
Nutritional teratogens: a survey of epidemiological literature.
Topics: Caffeine; Coffee; Congenital Abnormalities; Deficiency Diseases; Diet; Ethanol; Female; Fetal Alcoho | 1985 |
[The course of pregnancy in a representative Swiss sample (Aarau Pregnancy and Newborn Infant Study). II. Stimulants in pregnancy].
Topics: Adult; Alcohol Drinking; Caffeine; Child Behavior; Female; Humans; Infant, Newborn; Pregnancy; Sampl | 1985 |
Acute abstinence syndrome after epidural injection of butorphanol.
Topics: Adult; Anesthesia, Epidural; Aspirin; Blood Pressure; Butorphanol; Caffeine; Cesarean Section; Codei | 1985 |
Effects of common environmental exposures on spontaneous abortion of defined karyotype.
Topics: Abortion, Spontaneous; Alcohol Drinking; Caffeine; Contraceptives, Oral; Environmental Exposure; Fem | 1985 |
Reduction of caffeine teratogenicity in mice by inducing maternal drug metabolism with beta-naphthoflavone.
Topics: Abnormalities, Drug-Induced; Animals; Benzoflavones; beta-Naphthoflavone; Caffeine; Cytochrome P-450 | 1985 |
[Determination of theophylline and caffeine in blood serum by thin-layer chromatography-densitometry].
Topics: Caffeine; Chromatography, Thin Layer; Densitometry; Evaluation Studies as Topic; Female; Fetal Blood | 1985 |
Theophylline and fibrocystic breast disease.
Topics: Adult; Age Factors; Asthma; Caffeine; Estrogens; Female; Fibrocystic Breast Disease; Humans; Menopau | 1985 |
The effect of caffeine ingestion on pharmacokinetics of caffeine and its metabolites after a single administration in pregnant rats.
Topics: Administration, Oral; Animals; Caffeine; Female; Injections, Intravenous; Kinetics; Pregnancy; Rats; | 1985 |
Effects of caffeine ingestion during pregnancy.
Topics: Abnormalities, Multiple; Abortion, Spontaneous; Adult; Anemia; Caffeine; Chromosome Aberrations; Chr | 1985 |
Developmental and cytogenetic effects of caffeine on mouse blastocysts, alone or in combination with benzo(a)pyrene.
Topics: Animals; Benzo(a)pyrene; Blastocyst; Caffeine; Cells, Cultured; Dose-Response Relationship, Drug; Dr | 1985 |
[Effect of caffeine on fetal heart rate and caffeine consumption habits in pregnant patients].
Topics: Caffeine; Female; Fetal Heart; Heart Rate; Humans; Myocardial Contraction; Pregnancy; Pregnancy Trim | 1985 |
[Determination of caffeine and metamizole elimination in pregnancy and after delivery as an in vivo method for characterization of various cytochrome p-450 dependent biotransformation reactions].
Topics: Adolescent; Adult; Aminopyrine; Biotransformation; Caffeine; Cytochrome P-450 Enzyme System; Dipyron | 1985 |
Caffeine disposition after oral administration to pregnant rats.
Topics: Administration, Oral; Amniotic Fluid; Animals; Caffeine; Female; Fetus; Pregnancy; Rats; Theobromine | 1985 |
[Determination of caffeine and dimethylxanthines in biological fluids and tissues by high performance liquid chromatography].
Topics: Animals; Body Fluids; Caffeine; Chromatography, High Pressure Liquid; Female; Pregnancy; Rats; Theop | 1985 |
Genetic control of dicumarol levels in man.
Topics: Adult; Antipyrine; Caffeine; Centrifugation; Coffee; Dicumarol; Female; Genetics, Medical; Humans; M | 1968 |
Effect of oxytocin and epinephrine on the adenylate cyclase activity of myometrium from pregnant Rhesus monkeys.
Topics: Adenylyl Cyclases; Animals; Caffeine; Carbon Isotopes; Epinephrine; Female; Haplorhini; Macaca; Oxyt | 1973 |
Adenyl cyclase activity in the rabbit ovary.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals | 1969 |
Organ culture of fetal rat pancreas. I. Insulin release induced by caffeine and by sugars and some derivatives.
Topics: Alcohols; Animals; Biological Transport; Caffeine; Carbohydrates; Culture Media; Culture Techniques; | 1969 |
The stimulatory effect of luteinizing hormone on adenyl cyclase in the bovine corpus luteum.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals | 1970 |
Adenosine 3',5'-cyclic phosphate phosphodiesterase of corpus luteum.
Topics: Animals; Caffeine; Cattle; Corpus Luteum; Cyclic AMP; Estrus; Female; Humans; Hydrogen-Ion Concentra | 1971 |
[Biological properties of human placental lactogen (HPL; human chorionic somatomammotropin)].
Topics: Adipose Tissue; Animals; Blood Glucose; Caffeine; Cyclic AMP; Enzyme Induction; Epididymis; Epinephr | 1972 |
[Demonstration of 3'5'-cyclic AMP phosphodiesterase activity in the human placenta at term].
Topics: Caffeine; Cyclic AMP; Epinephrine; Female; Fluorides; Humans; Imidazoles; Luteinizing Hormone; Norep | 1972 |
A micro-method for the measurement of pharmacologically induced changes in purine derivatives.
Topics: Adenine; Animals; Caffeine; Chromatography, Thin Layer; Cricetinae; Cyclic AMP; Estrogens, Conjugate | 1973 |
Effect of prostaglandins and epinephrine on the level of cyclic AMP-14C of smooth muscle from the rhesus monkey.
Topics: Adenylyl Cyclases; Animals; Caffeine; Carbon Radioisotopes; Colon; Cyclic AMP; Depression, Chemical; | 1973 |
Effects of small intravenous doses of epinephrine on serum insulin, glucose tolerance and serum free fatty acids.
Topics: Adolescent; Adult; Anxiety Disorders; Biological Assay; Blood Glucose; Caffeine; Epinephrine; Fatty | 1974 |
[Are coffee and alcohol consumption risk factors in pregnancy? (author's transl)].
Topics: Age Factors; Alcohol Drinking; Birth Weight; Body Weight; Caffeine; Coffee; Ethanol; Female; Fetal D | 1974 |
Reduction in frequency of fetopathic effects of caffeine in mice by pretreatment with propranolol.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Catecholamines; Female; Fetus; Humans; Maternal-Feta | 1974 |
[Histological studies on the effects of caffeine on the embryonic development of limbs in mice].
Topics: Animals; Caffeine; Extremities; Female; Fetus; Maternal-Fetal Exchange; Mice; Pregnancy | 1972 |
The inhibitory action of caffeine on the smooth muscles of mouse myometrium and guinea pig ileum.
Topics: Animals; Caffeine; Calcium; Evoked Potentials; Female; Guinea Pigs; Ileum; Membrane Potentials; Mice | 1973 |
Fetal hypoproteinemia associated with generalized edema caused by administration of methyl xanthines to the rat during late pregnancy.
Topics: Animals; Blood Proteins; Body Water; Body Weight; Caffeine; Edema; Female; Fetal Diseases; Fetus; Ge | 1973 |
Proceedings: Prevention of embryopathic effects of caffeine in mice by pretreatment with propranolol.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Embryo, Mammalian; Female; Humans; Mice; Pregnancy; | 1974 |
[Clinical experiences with Fortalidon in painful conditions in gynecology and obstetrics].
Topics: Aminopyrine; Analgesics; Aspirin; Barbiturates; Caffeine; Codeine; Drug Combinations; Female; Genita | 1972 |
[Teratogenic effect of caffeine on the development of extremities in mice].
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Female; Gestational Age; Limb Deformities, Congenita | 1973 |
Genetic tests in mice of caffeine alone and in combination with mutagens.
Topics: Animals; Body Weight; Caffeine; Cobalt Isotopes; Embryo Implantation; Embryo, Mammalian; Female; Gen | 1973 |
Exposure of four generations of mice to caffeine in drinking water.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Breeding; Caffeine; Dose-Response Relationship, D | 1973 |
Use of stable isotopes in measuring low concentrations of drugs and drug metabolites by GC-MS-COM procedures.
Topics: Amniotic Fluid; Barbiturates; Caffeine; Carbon Isotopes; Child; Chromatography, Gas; Colostrum; Comp | 1973 |
[Caffeine, coffee, headache and migraine].
Topics: Adrenal Glands; Animals; Caffeine; Female; Glucose; Headache; Hemodynamics; Humans; Hypertension; Ma | 1973 |
A suggestion for reducing the incidence of habitual analgesic consumption.
Topics: Analgesics; Caffeine; Female; Humans; Pregnancy; Substance-Related Disorders | 1973 |
Caffeine as teratogen and mutagen.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Chromosome Aberrations; Female; Fetal Death; Fetus; | 1973 |
Effect on the offspring of repeated caffeine administration to pregnant rats.
Topics: Animals; Birth Weight; Caffeine; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Fetal | 1973 |
The use of gass chromatography-mass spectrometry methods in perinatal pharmacology.
Topics: Barbiturates; Caffeine; Chromatography, Gas; Female; Fetus; Humans; Infant, Newborn; Mass Spectromet | 1973 |
Physicochemical factors in maternal-fetal distribution of drugs.
Topics: Amphetamine; Aniline Compounds; Animals; Antipyrine; Aspirin; Atropine; Benzoates; Caffeine; Carbon | 1973 |
[Pharmacological studies on the vascular system of the human placenta].
Topics: Acetylcholine; Atropine; Blood Vessels; Caffeine; Carbon Dioxide; Ephedrine; Epinephrine; Ergotamine | 1974 |
Organ culture of fetal rat pancreas. IV. Effects of metabolic inhibitors on insulin release.
Topics: Animals; Binding Sites; Biological Transport, Active; Caffeine; Citrates; Female; Glucose; Heptoses; | 1971 |
Identification of drugs in the preimplantation blastocyst and in the plasma, uterine secretion and urine of the pregnant rabbit.
Topics: Animals; Barbiturates; Caffeine; Carbon Isotopes; DDT; Embryo Implantation; Endometrium; Female; Iso | 1971 |
Use of a tannic acid-caffeine concentration procedure for detecting urinary proteins and hemagglutinins.
Topics: Antibodies; Blood Group Antigens; Caffeine; Electrophoresis; Erythroblastosis, Fetal; Female; Humans | 1968 |
Adverse effects of prolonged administration of caffeine on rat fetus.
Topics: Abnormalities, Drug-Induced; Animals; Blood Cell Count; Body Weight; Caffeine; Diet; Edema; Esophagu | 1972 |
[Iatrogenic damage in pediatrics].
Topics: Anti-Bacterial Agents; Bismuth; Caffeine; Child; Child, Preschool; Digitalis Glycosides; Diuretics; | 1971 |
[The pharmacodynamic action of caffeine. Deductions in clinical obstetrics].
Topics: Abortion, Threatened; Animals; Caffeine; Drug Synergism; Female; Humans; Pregnancy; Progesterone; Ra | 1971 |
[Studies on the teratogenic influence of caffeine on the fetuses of white mice].
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Caffeine; Female; Limb Deformities, Congenit | 1970 |
Caffeine and nicotine penetrate the pre-implantation blastocyst.
Topics: Animals; Caffeine; Carbon Isotopes; Female; Gestational Age; Maternal-Fetal Exchange; Nicotine; Preg | 1969 |
Teratogenic actions of some methylated xanthines in mice.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Female; Fetus; Injections, Intraperitoneal; Male; Mi | 1969 |
Changes in plasma free fatty acids and triglycerides in dairy cattle after dosing with coffee or caffeine.
Topics: Animals; Caffeine; Cattle; Coffee; Fatty Acids, Nonesterified; Female; Lactation; Pregnancy; Triglyc | 1970 |
Goldenhar's syndrome and phocomelia. Case report and etiologic considerations.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Abortion, Threatened; Aspirin; Caffeine; Child | 1971 |
[Further studies on the growth inhibitory effect of hypnotics in embryos of Sinapis alba].
Topics: Caffeine; Chloral Hydrate; Chlorophyll; Depression, Chemical; Embryo, Mammalian; Embryo, Nonmammalia | 1967 |
[Obstetric practice].
Topics: Animals; Benzoates; Caffeine; Calcium Chloride; Cattle; Cattle Diseases; Female; Glucose; Injections | 1968 |
The effect of coffee on glucose tolerance in normal and prediabetic pregnant women.
Topics: Adult; Blood Glucose; Caffeine; Coffee; Female; Glucose Tolerance Test; Humans; Prediabetic State; P | 1969 |
Organ culture of fetal rat pancreas. II. Insulin release induced by amino and organic acids, by hormonal peptides, by cationic alterations of the medium and by other agents.
Topics: Acids; Adenylyl Cyclases; Amino Acids; Animals; Caffeine; Calcium; Culture Media; Culture Techniques | 1969 |