caffeine has been researched along with Postoperative Complications in 35 studies
Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The incidence of atrial fibrillation was similar in the caffeine and in the placebo group during hospital stay (33 vs." | 9.27 | Peri-operative oral caffeine does not prevent postoperative atrial fibrillation after heart valve surgery with cardiopulmonary bypass: A randomised controlled clinical trial. ( Bruder, N; Collart, F; Fenouillet, E; Gariboldi, V; Giorgi, R; Grisoli, D; Guidon, C; Guieu, R; Kerbaul, F; Lagier, D; Nee, L; Roux, N; Theron, A; Velly, L, 2018) |
| "To investigate the effects of different doses of oral caffeine-paracetamol combinations in postdural puncture headache (PDPH) prophylaxis." | 9.11 | Oral multidose caffeine-paracetamol combination is not effective for the prophylaxis of postdural puncture headache. ( Akpinar, H; Esmaoglu, A; Uğur, F, 2005) |
| "Interruption of daily caffeine consumption can cause caffeine withdrawal headache." | 9.08 | Perioperative administration of caffeine tablets for prevention of postoperative headaches. ( Drewe, J; Hampl, KF; Rüttimann, U; Schneider, MC; Ummenhofer, W, 1995) |
| " Tracings were analyzed for evidence of apnea, periodic breathing, and/or bradycardia by a pulmonologist unaware of the drug given." | 9.06 | High-dose caffeine suppresses postoperative apnea in former preterm infants. ( Fink, R; Hannallah, RS; Hicks, JM; Ruttimann, UE; Welborn, LG, 1989) |
| "This study examined the hypothesis that headache after general anesthesia is related to a caffeine withdrawal state." | 7.68 | Is caffeine withdrawal the mechanism of postoperative headache? ( Fennelly, M; Galletly, DC; Purdie, GI, 1991) |
| " The incidence of atrial fibrillation was similar in the caffeine and in the placebo group during hospital stay (33 vs." | 5.27 | Peri-operative oral caffeine does not prevent postoperative atrial fibrillation after heart valve surgery with cardiopulmonary bypass: A randomised controlled clinical trial. ( Bruder, N; Collart, F; Fenouillet, E; Gariboldi, V; Giorgi, R; Grisoli, D; Guidon, C; Guieu, R; Kerbaul, F; Lagier, D; Nee, L; Roux, N; Theron, A; Velly, L, 2018) |
| "To investigate the effects of different doses of oral caffeine-paracetamol combinations in postdural puncture headache (PDPH) prophylaxis." | 5.11 | Oral multidose caffeine-paracetamol combination is not effective for the prophylaxis of postdural puncture headache. ( Akpinar, H; Esmaoglu, A; Uğur, F, 2005) |
| "Interruption of daily caffeine consumption can cause caffeine withdrawal headache." | 5.08 | Perioperative administration of caffeine tablets for prevention of postoperative headaches. ( Drewe, J; Hampl, KF; Rüttimann, U; Schneider, MC; Ummenhofer, W, 1995) |
| "To determine whether prophylactic intravenous administration of caffeine, to daily caffeine users, decreases the frequency of postoperative headache and shortens recovery time." | 5.08 | Prophylactic intravenous administration of caffeine and recovery after ambulatory surgical procedures. ( Arnold, JJ; Danielson, DR; Ereth, MH; Klindworth, JT; Weber, JG, 1997) |
| " Tracings were analyzed for evidence of apnea, periodic breathing, and/or bradycardia by a pulmonologist unaware of the drug given." | 5.06 | High-dose caffeine suppresses postoperative apnea in former preterm infants. ( Fink, R; Hannallah, RS; Hicks, JM; Ruttimann, UE; Welborn, LG, 1989) |
| "This study examined the hypothesis that headache after general anesthesia is related to a caffeine withdrawal state." | 3.68 | Is caffeine withdrawal the mechanism of postoperative headache? ( Fennelly, M; Galletly, DC; Purdie, GI, 1991) |
| "Postoperative ileus is a common condition following abdominal surgery." | 3.01 | Does caffeine enhance bowel recovery after elective colorectal resection? A prospective double-blinded randomized clinical trial. ( Abu-Gazala, M; Bdolah-Abram, T; Gefen, R; Luques, L; Marom, G; Michael, S; Mintz, Y; Mizrahi, I; Parnasa, SY; Pikarsky, AJ; Rivkind, AI; Shussman, N, 2021) |
| "Caffeine citrate has been shown to be effective in treating apnea of prematurity." | 2.73 | Caffeine in children with obstructive sleep apnea. ( Chuang, AZ; Ganesan, BA; Ghelber, O; Khalil, SN; Maposa, D; Matuszczak, M; Rabb, MF; Tabrizi, HK, 2008) |
| "Hypoglycemia is increasingly recognized as a complication of bariatric surgery." | 2.55 | Medical nutrition therapy for post-bariatric hypoglycemia: practical insights. ( Anderson-Haynes, SE; Mulla, C; Patti, ME; Suhl, E, 2017) |
| "We report a case of aneurysmal subarachnoid hemorrhage (SAH) and severe, catheter-induced vasospasm during attempted endovascular repair of a ruptured anterior communicating artery (AComA) aneurysm in the setting of excessive energy drink consumption." | 2.53 | Aneurysmal subarachnoid hemorrhage and severe, catheter-induced vasospasm associated with excessive consumption of a caffeinated energy drink. ( Cord, BJ; Gilmore, E; Grant, RA; Kuzomunhu, L; Matouk, CC; Sheth, K, 2016) |
| "Headache is a common and distressing morbidity associated with day case surgery." | 1.32 | Perioperative headache and day case surgery. ( Buggy, DJ; Gill, PS; Guest, C; Rabey, PG, 2003) |
| " Compared with controls (n = 15), a significantly slowed caffeine absorption was found in gastric stasis (n = 8) by means of a lower absorption rate constant KA (0." | 1.27 | Effect of altered gastric emptying on caffeine absorption. ( Brachtel, D; Richter, E, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (14.29) | 18.7374 |
| 1990's | 8 (22.86) | 18.2507 |
| 2000's | 8 (22.86) | 29.6817 |
| 2010's | 10 (28.57) | 24.3611 |
| 2020's | 4 (11.43) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, TW | 1 |
| Wang, CC | 1 |
| Sung, WW | 1 |
| Ting, WC | 1 |
| Lin, CC | 1 |
| Tsai, MC | 1 |
| Lin, X | 1 |
| Li, XX | 1 |
| Dong, R | 1 |
| Wang, B | 1 |
| Bi, YL | 1 |
| Nasseri, Y | 1 |
| Kasheri, E | 1 |
| Oka, K | 1 |
| Zhu, R | 1 |
| Smiley, A | 1 |
| Cohen, J | 1 |
| Ellenhorn, J | 1 |
| Barnajian, M | 1 |
| Parnasa, SY | 1 |
| Marom, G | 1 |
| Bdolah-Abram, T | 1 |
| Gefen, R | 1 |
| Luques, L | 1 |
| Michael, S | 1 |
| Mizrahi, I | 1 |
| Abu-Gazala, M | 1 |
| Rivkind, AI | 1 |
| Mintz, Y | 1 |
| Pikarsky, AJ | 1 |
| Shussman, N | 1 |
| Suhl, E | 1 |
| Anderson-Haynes, SE | 1 |
| Mulla, C | 1 |
| Patti, ME | 1 |
| Evans, M | 1 |
| Lam, H | 1 |
| Austin, T | 1 |
| Samieirad, S | 1 |
| Afrasiabi, H | 1 |
| Tohidi, E | 1 |
| Qolizade, M | 1 |
| Shaban, B | 1 |
| Hashemipour, MA | 1 |
| Doaltian Shirvan, I | 1 |
| Lagier, D | 1 |
| Nee, L | 1 |
| Guieu, R | 1 |
| Kerbaul, F | 1 |
| Fenouillet, E | 1 |
| Roux, N | 1 |
| Giorgi, R | 1 |
| Theron, A | 1 |
| Grisoli, D | 1 |
| Gariboldi, V | 1 |
| Collart, F | 1 |
| Bruder, N | 1 |
| Velly, L | 1 |
| Guidon, C | 1 |
| Kuo, SC | 1 |
| Mu, PF | 1 |
| Chang, LY | 1 |
| Chou, SS | 1 |
| Lee, MY | 1 |
| Su, JY | 1 |
| Shih, CF | 1 |
| Curia, M | 1 |
| Kumar, M | 1 |
| Chawla, R | 1 |
| Haloi, P | 1 |
| Singh, M | 1 |
| Zelken, JA | 1 |
| Berli, JU | 1 |
| Grant, RA | 1 |
| Cord, BJ | 1 |
| Kuzomunhu, L | 1 |
| Sheth, K | 1 |
| Gilmore, E | 1 |
| Matouk, CC | 1 |
| Khalil, SN | 1 |
| Maposa, D | 1 |
| Ghelber, O | 1 |
| Rabb, MF | 1 |
| Matuszczak, M | 1 |
| Ganesan, BA | 1 |
| Tabrizi, HK | 1 |
| Chuang, AZ | 1 |
| Mitchell, A | 1 |
| McCrea, P | 1 |
| Inglis, K | 1 |
| Porter, G | 1 |
| Müller, SA | 1 |
| Rahbari, NN | 1 |
| Schmied, BM | 1 |
| Büchler, MW | 1 |
| Gill, PS | 1 |
| Guest, C | 1 |
| Rabey, PG | 1 |
| Buggy, DJ | 1 |
| Esmaoglu, A | 1 |
| Akpinar, H | 1 |
| Uğur, F | 1 |
| Hampl, KF | 2 |
| Schneider, MC | 2 |
| Rüttimann, U | 1 |
| Ummenhofer, W | 1 |
| Drewe, J | 1 |
| Nikolajsen, L | 1 |
| Larsen, KM | 1 |
| Kierkegaard, O | 1 |
| Stotz, G | 1 |
| Weber, JG | 1 |
| Klindworth, JT | 1 |
| Arnold, JJ | 1 |
| Danielson, DR | 1 |
| Ereth, MH | 1 |
| Hamill, NJ | 1 |
| Levin, RJ | 1 |
| Henderson-Smart, DJ | 2 |
| Steer, P | 2 |
| Carrera González, A | 1 |
| Sanz, F | 1 |
| de la Calle, B | 1 |
| Laustalet de la Fuente, J | 1 |
| Choi, DM | 1 |
| Davis, L | 1 |
| Moral Turiel, M | 1 |
| Rodríguez Simón, MO | 1 |
| Sahagún de la Lastra, J | 1 |
| Yuste Pascual, JA | 1 |
| Verhoeff, FH | 1 |
| Millar, JM | 1 |
| Fennelly, M | 1 |
| Galletly, DC | 1 |
| Purdie, GI | 1 |
| Bayless, TM | 1 |
| Harris, ML | 1 |
| Welborn, LG | 2 |
| Hannallah, RS | 2 |
| Fink, R | 2 |
| Ruttimann, UE | 2 |
| Hicks, JM | 1 |
| de Soto, H | 1 |
| Boeckx, R | 1 |
| Brachtel, D | 1 |
| Richter, E | 1 |
| Neumann, H | 1 |
| Scheiber, V | 1 |
| Nelson, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Does Caffeine Enhance Bowel Recovery After Colorectal Surgery?[NCT03097900] | Phase 2 | 70 participants (Actual) | Interventional | 2017-11-02 | Completed | ||
| Hypoglycemia and the Gut Microbiome[NCT03385707] | 28 participants (Anticipated) | Observational | 2019-02-07 | Recruiting | |||
| Demonstration of OTC Naproxen Sodium's (Aleve's) Anti-inflammatory Action in Dental Implant Surgery Patients[NCT04694300] | Phase 4 | 32 participants (Actual) | Interventional | 2021-02-07 | Completed | ||
| Prevention of Atrial Fibrillation Following Valvular Replacement With Cardiopulmonary Bypass: a Prospective, Randomized Clinical Study Comparing Oral Caffeine With Placebo[NCT01999829] | Phase 3 | 110 participants (Actual) | Interventional | 2013-10-31 | Completed | ||
| Post-operative Analgesia in Elective, Soft-tissue Hand Surgery: A Randomized, Double Blind Comparison of Acetaminophen/Ibuprofen Versus Acetaminophen/Hydrocodone[NCT02029235] | Phase 4 | 72 participants (Actual) | Interventional | 2015-02-10 | Terminated (stopped due to Early termination due to slower than anticipated recruitment.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Subjects asked to fill out a patient diary recording their pain intensity level (on 100mm Visual Analog Scale) prior to taking study medication every 4 hours.~The daily average pain intensity levels are reported as a score on a scale of 0-100, with higher score meaning worse outcome.~The daily average pain levels were assessed daily for 1 week post-operatively, then compared between the 2 groups using a two-group Student's t-test." (NCT02029235)
Timeframe: 1 week post-operatively
| Intervention | score on a scale (0-100, higher = worse) (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Daily average pain intensity level on PostOp Day 1 | Daily average pain intensity level on PostOp Day 2 | Daily average pain intensity level on PostOp Day 3 | Daily average pain intensity levelon PostOp Day 4 | Daily average pain intensity level on PostOp Day 5 | Daily average pain intensity level on PostOp Day 6 | Daily average pain intensity level on PostOp Day 7 | |
| Acetaminophen/Hydrocodone (AH) Group | 24.07 | 30.16 | 22.11 | 18.53 | 16.61 | 13.58 | 13.00 |
| Acetaminophen/Ibuprofen (AIBU) Group | 22.17 | 22.22 | 15.67 | 13.17 | 14.03 | 13.44 | 12.67 |
"Subjects asked to fill out a patient diary recording their pain relief (on a Likert scale) one hour after taking study medication every 4 hours.~Daily average pain relief scores are reported as a score on a scale of 0-3, with higher score meaning better outcome.~The daily average pain relief scores were assessed daily for 1 week post-operatively, then compared using generalized linear mixed-effects models" (NCT02029235)
Timeframe: 1 week postoperatively
| Intervention | score on a scale (0-3, higher = better) (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Daily average pain relief on PostOp Day 1 | Daily average pain relief on PostOp Day 2 | Daily average pain relief on PostOp Day 3 | Daily average pain relief on PostOp Day 4 | Daily average pain relief on PostOp Day 5 | Daily average pain relief on PostOp Day 6 | Daily average pain relief on PostOp Day 7 | |
| Acetaminophen/Hydrocodone (AH) Group | 1.53 | 1.76 | 2.33 | 2.46 | 2.54 | 2.84 | 2.88 |
| Acetaminophen/Ibuprofen (AIBU) Group | 1.84 | 2.27 | 2.63 | 2.91 | 2.88 | 2.87 | 2.96 |
6 reviews available for caffeine and Postoperative Complications
| Article | Year |
|---|---|
The effect of coffee/caffeine on postoperative ileus following elective colorectal surgery: a meta-analysis of randomized controlled trials.
Topics: Caffeine; Coffee; Colectomy; Colorectal Surgery; Humans; Ileus; Postoperative Complications; Randomi | 2022 |
Medical nutrition therapy for post-bariatric hypoglycemia: practical insights.
Topics: Alcohol Drinking; Bariatric Surgery; Caffeine; Central Nervous System Stimulants; Diet, Healthy; Die | 2017 |
Aneurysmal subarachnoid hemorrhage and severe, catheter-induced vasospasm associated with excessive consumption of a caffeinated energy drink.
Topics: Adult; Anterior Cerebral Artery; Caffeine; Catheters; Central Nervous System Stimulants; Cerebral An | 2016 |
Postoperative caffeine for preventing apnea in preterm infants.
Topics: Anesthesia, General; Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; In | 2000 |
Prophylactic caffeine to prevent postoperative apnea following general anesthesia in preterm infants.
Topics: Anesthesia, General; Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; In | 2001 |
Inflammatory bowel disease and irritable bowel syndrome.
Topics: Caffeine; Cholecystectomy; Colon; Colonic Diseases, Functional; Diarrhea; Humans; Ileum; Incidence; | 1990 |
13 trials available for caffeine and Postoperative Complications
| Article | Year |
|---|---|
Does coffee affect bowel recovery following minimally invasive colorectal operations? A three-armed randomized controlled trial.
Topics: Caffeine; Coffee; Colectomy; Colorectal Neoplasms; Humans; Ileus; Postoperative Complications; Time | 2023 |
Does caffeine enhance bowel recovery after elective colorectal resection? A prospective double-blinded randomized clinical trial.
Topics: Adult; Aged; Caffeine; Colorectal Neoplasms; Gastrointestinal Motility; Humans; Ileus; Length of Sta | 2021 |
Evaluation of caffeine versus codeine for pain and swelling management after implant surgeries: A triple blind clinical trial.
Topics: Adult; Analgesics, Opioid; Caffeine; Codeine; Dental Implantation; Double-Blind Method; Edema; Femal | 2017 |
Peri-operative oral caffeine does not prevent postoperative atrial fibrillation after heart valve surgery with cardiopulmonary bypass: A randomised controlled clinical trial.
Topics: Administration, Oral; Aged; Atrial Fibrillation; Caffeine; Cardiopulmonary Bypass; Central Nervous S | 2018 |
Caffeine in children with obstructive sleep apnea.
Topics: Caffeine; Central Nervous System Stimulants; Child; Child, Preschool; Double-Blind Method; Electrodi | 2008 |
A randomized, controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine (Tylenol 3) after outpatient breast surgery.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Breast Neoplasms; Ca | 2012 |
Can postoperative coffee perk up recovery time after colon surgery?
Topics: Caffeine; Central Nervous System Stimulants; Coffee; Colectomy; Defecation; Gastrointestinal Motilit | 2013 |
Oral multidose caffeine-paracetamol combination is not effective for the prophylaxis of postdural puncture headache.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthesia, Spinal; Caffeine; Central Nervous System | 2005 |
Perioperative administration of caffeine tablets for prevention of postoperative headaches.
Topics: Adult; Aged; Caffeine; Double-Blind Method; Female; Headache; Humans; Male; Middle Aged; Postoperati | 1995 |
Prophylactic intravenous administration of caffeine and recovery after ambulatory surgical procedures.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Caffeine; Central Nervous System Stimulants; Coffee; Dou | 1997 |
High-dose caffeine suppresses postoperative apnea in former preterm infants.
Topics: Anesthesia, General; Apnea; Bradycardia; Caffeine; Clinical Trials as Topic; Double-Blind Method; He | 1989 |
The use of caffeine in the control of post-anesthetic apnea in former premature infants.
Topics: Anesthesia, Inhalation; Apnea; Caffeine; Clinical Trials as Topic; Double-Blind Method; Hernia, Ingu | 1988 |
Fiorinal with codeine as a postoperative analgesic in dental surgery.
Topics: Adolescent; Adult; Anesthesia, Dental; Aspirin; Barbiturates; Caffeine; Child; Clinical Trials as To | 1971 |
16 other studies available for caffeine and Postoperative Complications
| Article | Year |
|---|---|
Habitual tea consumption and postoperative delirium after total hip/knee arthroplasty in elderly patients: The PNDABLE study.
Topics: Aged; Arthroplasty, Replacement, Knee; Biomarkers; Caffeine; Delirium; Humans; Life Style; Polypheno | 2022 |
Intravenous Caffeine Rescue for Postoperative Hypoventilation in a 16-Year-Old With Trisomy 10: A Case Report.
Topics: Administration, Intravenous; Adolescent; Anesthesia, Dental; Autistic Disorder; Caffeine; Central Ne | 2017 |
Effectiveness of coffee for postoperative ileus in patients following abdominal surgery: a systematic review protocol.
Topics: Abdomen; Caffeine; Coffee; Defecation; Digestive System Surgical Procedures; Humans; Ileus; Length o | 2018 |
The use of caffeine for the treatment of apnea of prematurity and bradycardia in a holoprosencephalic child with cleft lip and palate.
Topics: Apnea; Bradycardia; Caffeine; Central Nervous System Stimulants; Citrates; Cleft Lip; Cleft Palate; | 2013 |
Coffee, tea, and chocolate after microsurgery: why not?
Topics: Cacao; Caffeine; Coffee; Free Tissue Flaps; Humans; Ischemia; Microsurgery; Postoperative Care; Post | 2015 |
Perioperative headache and day case surgery.
Topics: Adult; Alcohol Drinking; Ambulatory Surgical Procedures; Caffeine; Female; Headache; Humans; Logisti | 2003 |
Effect of previous frequency of headache, duration of fasting and caffeine abstinence on perioperative headache.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Analgesics; Beverages; C | 1994 |
Postoperative transient hemihypaesthesia and severe headache associated with caffeine withdrawal.
Topics: Adult; Caffeine; Coffee; Female; Headache; Humans; Hypesthesia; Postoperative Complications; Substan | 1994 |
Caffeine withdrawal after head and neck surgery.
Topics: Caffeine; Carcinoma, Squamous Cell; Humans; Male; Middle Aged; Pharyngeal Neoplasms; Postoperative C | 1997 |
[Headache following dural puncture refractory to caffeine].
Topics: Adult; Anesthesia, Spinal; Arthroscopy; Caffeine; Drug Resistance; Dura Mater; Female; Headache; Hum | 2000 |
Postoperative recovery after inguinal herniotomy in ex-premature infants and the use of caffeine.
Topics: Apnea; Caffeine; Central Nervous System Stimulants; Hernia, Inguinal; Humans; Infant; Infant, Newbor | 2002 |
[Treatment of post-dural-puncture headache with intravenous cortisone].
Topics: Acetaminophen; Adult; Analgesics; Anesthesia, Epidural; Anesthesia, Obstetrical; Anti-Inflammatory A | 2002 |
Does caffeine contribute to postoperative morbidity?
Topics: Adult; Caffeine; Female; Headache; Humans; Male; Postoperative Complications | 1990 |
Is caffeine withdrawal the mechanism of postoperative headache?
Topics: Adult; Aged; Anesthesia, General; Caffeine; Female; Headache; Humans; Male; Middle Aged; Postoperati | 1991 |
Effect of altered gastric emptying on caffeine absorption.
Topics: Caffeine; Gastrectomy; Gastric Emptying; Humans; Intestinal Absorption; Postoperative Complications; | 1988 |
[Comparative studies on the analgesic effect of diphenyl-methoxy-benzylaminopropane-hydrochloride (ST 4250)].
Topics: Analgesics; Benzhydryl Compounds; Benzyl Compounds; Caffeine; Humans; Methyl Ethers; Pain; Phenaceti | 1973 |